Cell SurvivalSurvival RateMammalsCell LineApoptosisMolecular Sequence DataDisease-Free SurvivalSignal TransductionSurvivalAmino Acid SequenceCricetinaeCells, CulturedHeLa CellsTransfectionSurvival AnalysisBase SequenceGraft SurvivalCell Line, TumorTime FactorsMutationPhosphorylationProtein-Serine-Threonine KinasesCHO CellsProtein BindingRNA, MessengerRNA, Small InterferingDNA-Binding ProteinsCell ProliferationRecombinant ProteinsGene Expression RegulationCricetulusBlotting, WesternModels, BiologicalCloning, MolecularDNARecombinant Fusion ProteinsCell DeathRNA InterferenceTranscription FactorsCarrier ProteinsCOS CellsSequence Homology, Amino AcidProto-Oncogene ProteinsDNA DamageTreatment OutcomeGene ExpressionNuclear ProteinsMembrane ProteinsCercopithecus aethiopsCell CycleEmbryo, MammalianProto-Oncogene Proteins c-aktCell NucleusTranscription, GeneticTumor Cells, CulturedEnzyme ActivationMice, KnockoutPhosphatidylinositol 3-KinasesMice, Inbred C57BLPlasmidsFibroblastsProtein Structure, TertiaryTOR Serine-Threonine KinasesDNA RepairGenetic VectorsAntineoplastic AgentsProteinsImmunohistochemistryKaplan-Meier EstimateHEK293 CellsGreen Fluorescent ProteinsMicroscopy, FluorescenceAutophagyKineticsDNA, ComplementaryReverse Transcriptase Polymerase Chain ReactionRetrospective StudiesCell DivisionCell Cycle ProteinsDose-Response Relationship, DrugEnzyme InhibitorsProtein TransportProto-Oncogene Proteins c-bcl-2DNA PrimersMitochondriaSaccharomyces cerevisiaeMice, TransgenicNeoplasm Stagingbcl-X ProteinBinding SitesNIH 3T3 CellsNeuronsPromoter Regions, GeneticNeoplasmsCell MembraneCaspase 3CaspasesGene Knockdown TechniquesBreast NeoplasmsImmunoblotting