Cell CycleCell Cycle ProteinsCheckpoint Kinase 2DNA DamageS PhaseG2 PhaseGenes, cdcCell Cycle CheckpointsMitosisG1 PhaseAtaxia Telangiectasia Mutated ProteinsProtein-Serine-Threonine KinasesProtein KinasesCyclin-Dependent KinasesDNA RepairCyclinsDNA ReplicationPhosphorylationRetinoblastoma ProteinMammalsDNA-Binding ProteinsHydroxyureaCyclin-Dependent Kinase 2G2 Phase Cell Cycle CheckpointsTumor Suppressor Protein p53Cell Linecdc25 PhosphatasesNuclear ProteinsTumor Suppressor ProteinsE2F Transcription FactorsSaccharomyces cerevisiae ProteinsHeLa CellsCell DivisionSpindle ApparatusSaccharomyces cerevisiaeGamma RaysMutationS Phase Cell Cycle CheckpointsCDC2 Protein KinaseCyclin ESchizosaccharomycesModels, BiologicalCyclin BCyclin-Dependent Kinase Inhibitor p21Schizosaccharomyces pombe ProteinsM Phase Cell Cycle CheckpointsGenomic InstabilityMolecular Sequence DataAtaxia TelangiectasiaCDC2-CDC28 KinasesRadiation, IonizingUltraviolet RaysFungal ProteinsFibroblastsSignal TransductionNocodazoleApoptosisCyclin-Dependent Kinase 4Cyclin-Dependent Kinase Inhibitor p27Methyl MethanesulfonateCell Line, TumorIntracellular Signaling Peptides and ProteinsAmino Acid SequenceRadiation ToleranceTranscription FactorsCells, CulturedDNA, FungalG1 Phase Cell Cycle CheckpointsTranscription Factor DP1Retinoblastoma-Binding Protein 1DNAE2F1 Transcription FactorCyclin B1HistonesBase SequenceProtein BindingFlow CytometryKinetochoresDNA Breaks, Double-StrandedCell NucleusChromosomal InstabilityNucleic Acid Synthesis InhibitorsCarrier ProteinsExodeoxyribonucleasesCaffeineTransfectionGenes, FungalTumor Cells, CulturedBRCA1 ProteinCell SurvivalGene DeletionHCT116 CellsAnaphaseDose-Response Relationship, RadiationCell ProliferationRNA, Small InterferingTelomereSecurinChromatinGenes, p53