G(M2) Activator ProteinSphingolipid Activator ProteinsEnzyme ActivationMolecular Sequence DataAmino Acid SequenceSignal TransductionSaposinsG(M2) GangliosideTranscription Factor AP-1Base SequenceTissue Plasminogen ActivatorTranscription FactorsPromoter Regions, GeneticDNA-Binding ProteinsB-Lymphocyte SubsetsCyclic AMP Receptor ProteinB-Cell-Specific Activator ProteinPlasminogen Activator Inhibitor 1Transcription, GeneticUrokinase-Type Plasminogen ActivatorB-LymphocytesProto-Oncogene Proteins c-junbeta-N-AcetylhexosaminidasesCell LineHexosaminidase ACells, CulturedTrans-ActivatorsMammalsProtein BindingBinding SitesTranscription Factor AP-2RNA, MessengerGene Expression RegulationGangliosidosesMutationGangliosidoses, GM2Transcriptional ActivationProto-Oncogene Proteins c-fosMonoglyceridesTransfectionDNAMice, Inbred C57BLLymphocyte ActivationEscherichia coliCloning, MolecularProteinsGerminal CenterSpleenTay-Sachs DiseaseRecombinant ProteinsImmunoglobulin MMice, KnockoutPhosphorylationReceptors, Urokinase Plasminogen ActivatorCell DifferentiationKineticsRecombinant Fusion ProteinsPlasminogen ActivatorsNuclear ProteinsRepressor ProteinsImmunoglobulin DPlasmidsHexosaminidase BGlycoproteinsReceptors, Cyclic AMPMice, TransgenicSequence Homology, Amino AcidGlycosphingolipidsBacterial ProteinsHeLa CellsNF-kappa BGene ExpressionMice, Inbred BALB CFlow CytometryBlotting, WesternDNA PrimersAntigens, CD19Saccharomyces cerevisiae ProteinsSaccharomyces cerevisiaeLeukodystrophy, MetachromaticRNA Polymerase Sigma 54Fos-Related Antigen-2Fungal ProteinsCarrier ProteinsJNK Mitogen-Activated Protein KinasesGenes, ReporterB-Cell Activating FactorImmunoglobulin Heavy ChainsTumor Cells, CulturedProtein Structure, TertiaryGene Expression Regulation, BacterialMitogen-Activated Protein KinasesSphingolipidosesReverse Transcriptase Polymerase Chain ReactionApoptosisLymphocyte CooperationCell Line, TumorElectrophoretic Mobility Shift AssayMembrane ProteinsUp-Regulation