• Feschotte's work on the hAT transposon is the first time that a "jumping gene" has been shown to have entered mammalian genomes, and the first time it has been shown to do so in at around the same time, in a range of unrelated species, in different parts of the world. (newscientist.com)
  • A research team led by biophysical chemist Professor Edward Lemke has engineered a designer organelle in a living mammalian cell in a new complex biological translation process. (news-medical.net)
  • Mammalian Chromosome Engineering: Methods and Protocols provides the reader with up-to date information on this rapidly evolving field and strives to take the reader into the exciting realm of chromosomal engineering from the basic principles to the practical applications of these new technologies. (springer.com)
  • Authoritative and cutting-edge, Mammalian Chromosome Engineering: Methods and Protocols serves as a bench-side resource for current protocols and aims to help scientists to explore the many prospects for future research and vital applications. (springer.com)
  • Does anyone know of any mammalian expression vectors which produces a tag which can be used for co-immunoprecipitation studies and allows blue/ white selection in E.coli? (bio.net)
  • This is the most exciting development to come out of my laboratory since we cloned the mammalian circadian gene, Clock, in 1997. (eurekalert.org)
  • The generation of an excitatory receptor current in mammalian olfactory sensory neurons (OSNs) involves the sequential activation of two distinct types of ion channels: cAMP-gated Ca 2+ -permeable cation channels and Ca 2+ -gated Cl - channels, which conduct a depolarizing Cl - efflux. (jneurosci.org)
  • Our results provide a basis for translating odorants into receptor neuron responses and for unraveling mammalian odor coding. (sciencemag.org)
  • Identification of mammalian olfactory receptor agonists enables development of a predictive model of receptor activation. (sciencemag.org)
  • An in-depth understanding of the molecular role that autophagy plays in pathological settings is vital for both the diagnosis and treatment of mammalian diseases and will aid in the search for novel targets for therapeutic drug intervention. (royalsocietypublishing.org)
  • mTOR Complex 1 (mTORC1) is composed of mTOR, regulatory associated protein of mTOR (Raptor), and mammalian LST8/G-protein β-subunit like protein (mLST8/GβL). (bionity.com)
  • Genetic and phylogenetic analyses of two MRV3 isolates revealed that they differed significantly from non-pathogenic mammalian orthoreoviruses circulating in the USA. (cabi.org)
  • They suggest that the incorporation of the bones of the primary jaw joint into the ear has considerably increased the genetic, regulatory, and developmental complexity of the mammalian ear, which, in turn, has increased the degrees of freedom for an independent adaptation of the different functional ear units. (newswise.com)
  • The incorporation of the bones of the primary jaw joint into the ear has considerably increased the genetic, regulatory, and developmental complexity of the mammalian ear. (newswise.com)
  • Writing in Monday's edition of Proceedings of the National Academy of Sciences (PNAS) , organismal biology and anatomy professor Dr. Neil Shubin and his colleagues explained that the found the basic genetic machinery for mammalian limb development in a non-model fish known as the spotted gar. (redorbit.com)
  • We develop algorithms, systems and software architectures for automating reconstruction of accurate representations of neural tissue structures, such as nanometer-scale neurons' morphology and synaptic connections in the mammalian cortex. (mit.edu)
  • In mammalian systems, however, ligands are known for fewer than 50 of more than 1400 human and mouse ORs, greatly limiting our understanding of olfactory coding. (sciencemag.org)
  • Since hybrid information is so important to help identify biblical kinds, Mammalian Hybrids (Gray 1972) was used extensively. (answersingenesis.org)
  • This evolutionary transformation of the primary jaw joint into the mammalian ear ossicles is one of the most iconic transitions in vertebrate evolution, but it is not clear why this complex transition has happened. (newswise.com)
  • The Austrian research team proposed that this substantial evolutionary change of mammalian ear anatomy has - in addition to any direct enhancements of mastication and hearing - also increased the "evolvability" (capacity for adaptive evolution) of the ear and its associated sensory functions. (newswise.com)
  • The evolution of mammalian auditory ossicles was an evolutionary event in which bones in the jaw of reptiles were co-opted to form part of the hearing apparatus in mammals . (wikipedia.org)
  • The rhesus macaque was one of 19 mammals included in a study reconstructing chromosome rearrangements during 105 million years of mammalian evolution. (rvc.ac.uk)
  • The Evolution of Lactation in Mammalian Species. (bioportfolio.com)
  • The purpose of this brief review is not to examine all past theories of mammary evolution but to consider the evolution of the mammary gland in relation to (1) modern paleobiology, giving special attention to the mammaliaforms which had many mammalian features, including delayed tooth development suggestive of milk intake. (bioportfolio.com)
  • The development of the mammary glands and the process of lactation is an integral component of mammalian evolution, and suckling has been essential for the survival of the neonates of most mammalian s. (bioportfolio.com)
  • This is the first study that has successfully identified the factors responsible for the onset of heart formation in the mammalian embryo. (newswise.com)
  • Mammalian embryogenesis is the process of cell division and cellular differentiation during early prenatal development which leads to the development of a mammalian embryo . (bionity.com)
  • These methods draw attention to mammalian synthetic biology and can even spark collaboration at workshops such as the SBE International Mammalian Synthetic Biology Workshop (May 5-6, 2018, Boston, MA). (aiche.org)
  • They suggest that despite the tight spatial entanglement of functional ear components, the increased evolvability of the mammalian ear may have contributed to the evolutionary success and adaptive diversification of mammals in the vast diversity of ecological and behavioral niches observable today. (newswise.com)
  • This got them curious, so they ventured to neighboring labs, the Jerusalem Biblical Zoo and the Kimron Veterinary Institute to examine pancreases from across the mammalian class, from Etruscan shrews (the smallest mammals in the world) to giraffes (the tallest). (eurekalert.org)
  • By investing both major mammalian orders and closely related rodent species, we can understand the greater context for the first steps of evolutionary change between species. (ox.ac.uk)
  • We have created maps of transcription factor binding, chromatin organising proteins and active enhancers and promoters across a large number of mammalian species in an attempt to understand these changes at a molecular level. (ox.ac.uk)
  • These studies will allow us to determine the role of chromosome rearrangements in the formation of new mammal species and how such rearrangements result in adaptive changes that are specific to the different mammalian lineages. (rvc.ac.uk)
  • A variety of proteins are classed under this heading including some secretoglobin subtypes that appear unique to a particular mammalian species, and others whose functions differ between species. (bioportfolio.com)
  • Mammalian Species is a peer-reviewed scientific journal published by the American Society of Mammalogists. (wikipedia.org)
  • The DNA Isolation Kit for Mammalian Blood rapidly isolates DNA from 1 to 10 ml mammalian whole blood, lymphocytes, or buffy coat samples. (sigmaaldrich.com)
  • Here, we provide an integrated review of recent studies implicating autophagy dysfunction in the progression of mammalian disorders and summarize research suggesting that the molecular pathways involved in autophagy could serve as potential therapeutic targets. (royalsocietypublishing.org)
  • These taxa can be grouped into six consecutive faunal associations that show some correspondence with the qualitative mammalian chronofaunas of previous workers. (pnas.org)
  • Our studies show that active mammalian AMPK displays significantly tighter binding to ADP than to Mg-ATP, explaining how the enzyme is regulated under physiological conditions where the concentration of Mg-ATP is higher than that of ADP and much higher than that of AMP. (rcsb.org)
  • This chapter focuses on mammalian cis-acting regulatory elements that had been recently discovered in different regions: pre-processed and mature. (intechopen.com)
  • The chapter begins with an overview of two large networks of mRNAs that contain conserved AU-rich elements (AREs) or GU-rich elements (GREs), and their role in mammalian cell physiology. (intechopen.com)
  • Therefore, RNAi, with its characteristic efficacy at very low concentrations of siRNA, in the low nanomolar range, holds great promise for exploring gene function in mammalian cell cultures. (pnas.org)