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  • patients
  • The aim of this study was to investigate the distribution of all four naïve and memory subsets composing the CD4 + and CD8 + T-cell pools in paired blood and pleural fluid from a large cohort of consecutive patients with MPM before any treatment. (biomedcentral.com)
  • fluid
  • Blood and pleural fluid were also obtained from healthy subjects, providing normal values for T cell populations. (biomedcentral.com)
  • Effector memory T cells were the main T cell subpopulation in pleural fluid from healthy subjects. (biomedcentral.com)
  • In contrast, there was a striking and selective recruitment of central memory CD4+ T cells in MPE, but not of effector cells CD8 + T cells or NK cells in the pleural fluid as one would expect in order to obtain an efficient immune response. (biomedcentral.com)
  • Comparing for the first time MPE to pleural fluid from healthy subjects, we found a local defect in recruiting effector CD8 + T cells, which may be involved in the escape of tumor cells from immune response. (biomedcentral.com)
  • mesothelial
  • Pleuritis Pleural mesothelial hyperplasia Pleural calcified fibrous pseudotumor Pleural plaques: discrete fibrous or partially calcified thickened area which can be seen on X-rays of individuals exposed to asbestos. (wikipedia.org)
  • Cells
  • Toll like receptor 7 expressed by malignant cells promotes tumor progression and metastasis through the recruitment of myeloid derived suppressor cells. (bioportfolio.com)
  • The whorled eosinophilic inclusions in LCLC-RP cells give it a microscopic resemblance to malignant cells found in rhabdomyosarcoma (RMS), a rare neoplasm arising from transformed skeletal muscle. (wikipedia.org)
  • exposure
  • Pleural plaques are the most common manifestation of asbestos exposure, affecting up to 58% of asbestos-exposed workers. (wikipedia.org)
  • Pleural plaques are evidence of past asbestos exposure and indicate an increased risk for the future development of other asbestos-related diseases. (wikipedia.org)
  • pleurodesis
  • She underwent repeated thoracentesis, transbronchial lung biopsy (TBLB), bronchoalveolar lavage (BAL), and thoracoscopic pleural biopsy with talc pleurodesis. (docplayer.net)