• Infratentorial primitive neuroectodermal tumor that is, by definition, malignant and invasive and thus classified as Grave IV by the WHO. (uchicago.edu)
  • Along with neurofibroma, schwannoma constitutes one of the two most common benign peripheral nerve sheath tumors. (medscape.com)
  • Of note, the benign nerve sheath tumors are classified as World Health Organization (WHO) grade I on the basis of their benign cytologic features, in contrast to the malignant counterparts, which are WHO grade III or IV. (medscape.com)
  • more precisely, a benign epithelial neoplasm consisting of villous or arborescent outgrowths of fibrovascular stroma covered by neoplastic cells. (lookformedical.com)
  • INTRODUCTION: Benign intraosseous maxillary tumors, although uncommon among the adolescents, represent a major challenge to the maxillofacial surgeons. (bvsalud.org)
  • AIM OF THE WORK: To investigate the clinical and pathological patterns, treatment, and outcome of benign intraosseous maxillary tumors in adolescents. (bvsalud.org)
  • PATIENTS AND METHODS: A 10-years prospective study included patients between 12-18 years who presented with benign intraosseous maxillary tumors and surgically treated (conservative surgery or radical resection) with immediate reconstruction. (bvsalud.org)
  • A benign or malignant neoplasm that arises from the brain or the spinal cord. (beds.ac.uk)
  • While most tumors metastatic to the serous membranes are of epithelial origin, cytologists should be aware that non-epithelial neoplasms can also cause malignant effusions including sarcomas, melanomas, germ cell tumors, and, more rarely, brain tumors. (cytojournal.com)
  • Other rare non-epithelial malignancies that may be encountered in effusion cytology include neuroblastoma, Wilms tumor, and metastatic brain tumors. (cytojournal.com)
  • 1 - 3 Intracranial brain tumors, most commonly medulloblastoma [ Figure 2 ], can metastasize to the peritoneal cavity via ventriculo-peritoneal shunts used to divert excess cerebrospinal fluid. (cytojournal.com)
  • The Utility of Whole Body Imaging in the Evaluation of Solitary Brain Tumors. (beds.ac.uk)
  • Medulloblatoma is the most common posterior fossa (i.e. infratentorial) tumor in children (although some sources will state that it is the second most common behind cerebellar astrocytoma), making up approximately 18% of all primary pediatric brain tumors. (uchicago.edu)
  • Note: In children, brain tumors are the most common solid tumor and the second most common malignancy (after leukemia). (uchicago.edu)
  • Approximately 60% of brain tumors are infratentorial, 25% are supratentorial, and 15% arise in the midline. (uchicago.edu)
  • Although the mortality rate for children with brain tumors has decreased significantly over the last 40 years, deaths from childhood brain tumors are the highest among all childhood cancer deaths. (uchicago.edu)
  • There is also significant neurological morbidity associated with brain tumors. (uchicago.edu)
  • Long-term sequelae of childhood brain tumors are often from the effects of chemotherapy and/or radiation therapy. (uchicago.edu)
  • 1. Crawford, J. Childhood Brain Tumors. (uchicago.edu)
  • The same age differential is noted with respect to the more common odontogenic tumors (eg, ameloblastoma, odontoma, adenomatoid odontogenic tumor, calcifying epithelial odontogenic tumor, ameloblastic fibroma, odontogenic myxoma, odontogenic fibroma). (medscape.com)
  • The most common odontogenic tumors were adenomatoid odontogenic tumor and ameloblastoma (10.5% each). (bvsalud.org)
  • The presence of a noninvasive tumor next to a peripheral nerve suggests the diagnosis of neurilemmoma. (medscape.com)
  • An understanding of the relationship of the Schwann cell to other neuronal elements in the peripheral nervous system is helpful in conceptualizing the pathophysiology of a neurilemmoma. (medscape.com)
  • The histologic appearance of MNTI is usually that of a small, dark, cell neoplasm suggestive of neuroblastoma, rhabdomyosarcoma, Ewing sarcoma, lymphoma, desmoplastic small round cell tumor, and peripheral primitive neuroectodermal tumor. (medscape.com)
  • The differential diagnosis of a malignant effusion is accordingly broad, especially for the small round blue cell tumors that includes not only mesenchymal tumors, but also non-mesenchymal tumors, such as neuroblastoma and Wilms tumor. (cytojournal.com)
  • [ 12 ] There have also been reports of nerve sheath tumors exhibiting histologic hybrid features of schwannoma and soft-tissue perineurioma. (medscape.com)
  • Consider clinical, radiographic, laboratory, and histologic findings when establishing a proper differential diagnosis for melanotic neuroectodermal tumor of infancy (MNTI). (medscape.com)
  • Neville B, Damm D, Allen C. Melanotic Neuroectodermal Tumor of Infancy. (medscape.com)
  • Melanotic neuroectodermal tumor of infancy--a neoplasm of neural crese origin. (medscape.com)
  • Cutler LS, Chaudhry AP, Topazian R. Melanotic neuroectodermal tumor of infancy: an ultrastructural study, literature review, and reevaluation. (medscape.com)
  • OBJECTIVE: The aim of this systematic review was to determine the computed tomographic (CT) imaging characteristics of maxillary and mandibular melanotic neuroectodermal tumor of infancy (MNTI). (bvsalud.org)
  • As malignant cells have a tendency to round up in body fluids these non-epithelial neoplasms can therefore mimic reactive mesothelial cells and metastatic adenocarcinoma. (cytojournal.com)
  • Most tumors metastatic to the serous membranes are of epithelial origin. (cytojournal.com)
  • 1.5 cm diameter) residual tumor by postoperatively imaging, and no evidence of metastatic spread within the neuraxis. (uchicago.edu)
  • Medulloblastoma is a highly radiosensitive tumor. (uchicago.edu)
  • Common non-epithelial neoplasms that may cause malignant effusions include malignant melanoma, sarcomas, and other neoplasms including germ cell tumors [ Figure 1 ]. (cytojournal.com)
  • The MNTI often presents as a fast-growing lesion, suggesting a clinical impression of infection or malignant neoplasm. (medscape.com)
  • The identification of this second cell population helps differentiate MNTI from other small, round, blue cell tumors. (medscape.com)
  • Neurilemmomas may affect any location in the course of the peripheral nervous system (ie, cranial and spinal nerve roots, cranial and peripheral nerves, end-organ receptors, small nerve twigs). (medscape.com)
  • Diagnosing non-epithelial malignancies in effusion specimens based entirely upon their cytomorphologic features is difficult because these neoplasms often exhibit considerable morphological overlap and their cytomorphology can differ from the original tumor. (cytojournal.com)
  • 4 Malignant effusions caused by non-epithelial neoplasms are more frequently encountered in children than in adults. (cytojournal.com)
  • The peripheral nervous system can be defined as nervous tissue outside the brain and spinal cord. (medscape.com)
  • Malignant neoplasms arising in the neuroectoderm, the portion of the ectoderm of the early embryo that gives rise to the central and peripheral nervous systems, including some glial cells. (bvsalud.org)
  • It is generally accepted that in embryogenesis, the Schwann cells are derived from the neural crest and are of neuroectodermal origin. (medscape.com)
  • Depends on the size, subtype, and dissemination of the tumor at the time of diagnosis. (uchicago.edu)
  • KCTD11 is a tumor suppressor gene on 17p that inhibits the sonic hedgehog (SHH) signaling pathway, which is important for cellular proliferation and differentiation during cerebellar development. (uchicago.edu)
  • This number is even higher for patients who have tumors with favorable molecular phenotypes. (uchicago.edu)
  • As the peripheral nerves form, the Schwann cells migrate peripherally from the spinal ganglia, parallel to the axons, and encase them with their cytoplasm. (medscape.com)
  • BACKGROUND: The zygomatic implant perforated (ZIP) flap technique provides immediate reconstruction and rapid dental rehabilitation for low-level malignant tumors. (bvsalud.org)
  • CONCLUSIONS: Non-odontogenic tumors were more common than odontogenic tumors. (bvsalud.org)
  • Central giant cell granulomas and ossifying fibromas were the most common non-odontogenic tumors. (bvsalud.org)
  • To include biochemical and/or immunological markers which are specific for a tumour site (Table 2). (who.int)
  • Also to include the microscopic examination of peripheral blood films and trephine bone marrow aspirates. (who.int)
  • Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included. (lookformedical.com)