• Malignant melanoma is one of medicine's imitators, and metastatic disease can mimic cysts. (hindawi.com)
  • Final diagnosis was consistent with malignant melanoma, probably metastases. (hindawi.com)
  • In our hospital malignant melanoma is the most common primary cancer for metastatic disease to the breast [ 3 ]. (hindawi.com)
  • Specific ultrasound description of metastatic malignant melanoma in the breast is sparse, but the "cyst-like" hypoechogenic character with sharply demarcated margins has previously been reported [ 4 , 5 ]. (hindawi.com)
  • Unknown to the investigators she had, five months prior to the breast investigation, underwent a neck dissection with superficial parotidectomy, and histological examination of the specimen showed metastasis from malignant melanoma. (hindawi.com)
  • Median survival after diagnosis of breast metastases from malignant melanoma is 12,9 months [ 4 ]. (hindawi.com)
  • Malignant melanoma metastasis in the breast usually occurs in advanced-stage disease and the benefit of early detection is not known. (hindawi.com)
  • Qi J, Wang W, Lu W, Chen W, Sun H, Shang A. Design and biological evaluation of novel BF-30 analogs for the treatment of malignant melanoma. (jcancer.org)
  • LBF-14 holds potential to be developed as a promising once-weekly candidate for the treatment of malignant melanoma. (jcancer.org)
  • Wide local excision of malignant mucosal melanoma. (bmj.com)
  • Other cancers need to learn how to spread, but not melanoma," says Whitehead Member Robert Weinberg, an MIT professor of biology and senior author of a paper on the work in the journal Nature Genetics. (scienceblog.com)
  • Differentiating melanotic schwannoma from malignant melanoma is of utmost importance in planning of management. (thieme-connect.com)
  • Malignant tumors are aggressive, grow quickly, and often spread. (medlineplus.gov)
  • Carcinoids do not produce the malignant carcinoid syndrome until they are no longer confined to the small bowel or mesentery, perhaps because the liver breaks down the secretory products of tumors restricted to those locations. (medscape.com)
  • Tumors with skeletal muscle differentiation and malignant Schwann cells are classified as a subtype or a histologic variant of MPNST [ 9 , 10 ] and are referred to as malignant triton tumor (MTT) [ 11 ]. (hindawi.com)
  • In recent years, although significant progress has been made in the diagnosis and treatment of malignant tumors, breast cancer remains the leading cause of cancer-related deaths in women, largely due to its high rate of relapse, metastasis, and drug resistance [2-5]. (researchsquare.com)
  • Even histologically proven malignant tumors typically do not show ocular invasion or metastasis. (thieme-connect.com)
  • 6 Fu YS, Kaye GI, Lattes R. Primary malignant melanocytic tumors of the sympathetic ganglia, with an ultrastructural study of one. (thieme-connect.com)
  • The name was chosen to separate these tumors from ordinary malignancies (carcinomas), but by the 1950s, the fact that carcinoids could be malignant was obvious, thanks to Erspamer and Asero (1952), who identified serotonin production by carcinoid tumors. (medscape.com)
  • Indications for treatment of malignant hyperthermia (MH) with dantrolene include signs of hypermetabolism, a rapid rise in carbon dioxide in the face of an increase in the minute ventilation, tachycardia, muscle and or jaw rigidity (after succinylcholine), and fever (a late sign). (medscape.com)
  • For more information, see Malignant Hyperthermia in the Operating Room . (medscape.com)
  • Relevant information is available from the Malignant Hyperthermia Association of the United States (MHAUS) at www.mhaus.org . (medscape.com)
  • Malignant hyperthermia (MH) is a life-threatening clinical syndrome of hypermetabolism involving the skeletal muscle. (medscape.com)
  • Information about Malignant Hyperthermia specialities such as Malignant Hyperthermia in childbirth. (midcentraldhb.govt.nz)
  • The type of general anaesthetic used for emergency caesarean sections or other emergency surgery requires the use of the very drugs most likely to trigger malignant hyperthermia. (midcentraldhb.govt.nz)
  • It is therefore important that everyone caring for a woman at risk of malignant hyperthermia, or the partner of a man susceptible to malignant hyperthermia, knows that the risk is there. (midcentraldhb.govt.nz)
  • Malignant hyperthermia susceptibility is genetically transmitted. (midcentraldhb.govt.nz)
  • This means that a baby has a 50% chance of being susceptible to malignant hyperthermia if either of his parents is susceptible. (midcentraldhb.govt.nz)
  • The safest anaesthetic for a woman or baby at risk of malignant hyperthermia, is a regional anaesthetic. (midcentraldhb.govt.nz)
  • Surgery can then be carried out without pain, and without the risk of triggering malignant hyperthermia. (midcentraldhb.govt.nz)
  • It is therefore important to have more warning, and more preparation time, if a woman or baby is susceptible to malignant hyperthermia. (midcentraldhb.govt.nz)
  • Stress has sometimes been thought to be a cause of malignant hyperthermia. (midcentraldhb.govt.nz)
  • It has been postulated that the work and stress of labour may itself precipitate malignant hyperthermia. (midcentraldhb.govt.nz)
  • However, it is thought to be important to reduce the stress to the body during labour for women and babies at risk of malignant hyperthermia. (midcentraldhb.govt.nz)
  • Assessment in early pregnancy is important for women or babies at risk of malignant hyperthermia. (midcentraldhb.govt.nz)
  • DNA testing is carried out in some centres to test for malignant hyperthermia. (midcentraldhb.govt.nz)
  • DNA testing can be done on cord blood to allow earlier diagnosis of malignant hyperthermia susceptibility in the baby. (midcentraldhb.govt.nz)
  • Malignant carcinoid syndrome occurs in fewer than 10% of patients with a carcinoid tumor. (medscape.com)
  • Malignant carcinoid syndrome is not a cause of sustained hypertension , and a rise in blood pressure during flushing is rare. (medscape.com)
  • Bronchospasms are a less common sign of malignant carcinoid syndrome but may be severe. (medscape.com)
  • 2008). Advances in the systemic therapy of malignant pleural mesothelioma. (asbestslachtoffers.nl)
  • Current concepts in malignant pleural mesothelioma. (asbestslachtoffers.nl)
  • Malignant pleural mesothelioma (MPM) is a rare but lethal cancer associated with asbestos exposure. (asbestslachtoffers.nl)
  • Malignant pleural mesothelioma is an aggressive thoracic malignancy associated with exposure to asbestos, and its incidence is anticipated to increase during the first half of this century. (asbestslachtoffers.nl)
  • This Review summarizes the evidence supporting the clinical activity of chemotherapy, discusses the use of end points for its assessment and examines the influence of clinical and biochemical prognostic factors on the natural history of malignant pleural mesothelioma. (asbestslachtoffers.nl)
  • The diagnostic accuracy is close to 100% when all three modalities favour a benign or malignant diagnosis [ 1 ]. (hindawi.com)
  • An intermediate tumor is one that is between benign (slow-growing and unlikely to spread) and malignant (fast-growing, aggressive, and likely to spread). (medlineplus.gov)
  • Wang H , Han G , Chen J , . Heterogeneity of tumor immune microenvironment in malignant and metastatic change in LUAD is revealed by single-cell RNA sequencing. (aging-us.com)
  • Although several studies revealed the important role of immune cells and related marker genes impact on LUAD prognosis and process, a comprehensive understanding of TIME malignant and metastatic change in LUAD is still limited. (aging-us.com)
  • We take advantage of the similarity between neural developmental processes and cancer hierarchy to mitigate, if not completely abolish, the malignant nature of tumor cells and pave the way for new intervention strategies. (lu.se)
  • We aimed to identify if mxcmbn1 LG cells behave as malignant tumor cells and uncover the mechanism(s) underlying the malignancy of the mutant hemocytes. (bvsalud.org)
  • Rhabdomyoblastic differentiation in a malignant peripheral nerve sheath tumor (MPNST) is termed malignant triton tumor (MTT), a rare neoplasm that poses a diagnostic dilemma in the differential diagnosis of neck masses and portends poor prognosis. (hindawi.com)
  • Malignant peripheral nerve sheath tumor (MPNST) is a rare soft tissue neoplasm with a poor prognosis. (hindawi.com)
  • In terms of malignant transformation in cancer cells, interaction of cancer stem cells with endothelial cells or myofibroblasts as tumor microenvironmental cells was analyzed. (nii.ac.jp)
  • Medulloblastoma is the most common malignant brain cancer in children. (the-scientist.com)
  • In the Advanced Online Publication of Nature Genetics , Tobey MacDonald and colleagues from the Children's National Medical Center , Washington, DC, report the use of oligonucleotide expression profiling (Affymetrix G110 cancer arrays) to define a set of genes that are prognostic for medulloblastoma metastasis (DOI:10.1038/ng731). (the-scientist.com)
  • Malignant glioma is a fatal brain cancer which apparently has no cure. (healthjockey.com)
  • Oncogenic miR-20b-5p was confirmed to promote the malignant behaviors of breast cancer cells and BCSCs. (researchsquare.com)
  • Gastric cancer is the fourth commonest ently reported that H. pylori eradication were subjected to routine history and malignant disorder and the second com- can lead to a regression of acute gastritis clinical examination, fol owed by an monest cause of cancer-related death and intestinal metaplasia, and that such upper gastrointestinal endoscopic ex- worldwide [1]. (who.int)
  • They further applied the genome-wide RNA interference screening technique, so that they could determine the genes regulating the expression of a transcription factor called ATF5 in malignant glioma cells. (healthjockey.com)
  • Hypofractionated stereotactic radiotherapy (HFSRT) is one salvage treatment option in previously irradiated patients with recurrent malignant glioma. (biomedcentral.com)
  • Between 1997 and 2003, 19 patients with recurrent malignant glioma (14 glioblastoma on most recent histology, 5 anaplastic astrocytoma) were treated with HFSRT. (biomedcentral.com)
  • Despite intensive multi-modality treatment including tumor resection, post-operative radiotherapy and frequently adjuvant chemotherapy, the prognosis of malignant glioma continues to be poor. (biomedcentral.com)
  • Between 1997 and 2003, 19 patients were treated with hypofractionated stereotactic radiotherapy (HFSRT) for recurrent malignant glioma at the University of Würzburg, Germany. (biomedcentral.com)
  • Table 1 Clinical characteristics of n = 19 consecutive patients treated with hypofractionated stereotactic radiotherapy (HFSRT) for recurrent malignant glioma. (biomedcentral.com)
  • Table 2 Treatment details of hypofractionated stereotactic radiotherapy (HFSRT) in n = 19 consecutive patients with recurrent malignant glioma. (biomedcentral.com)
  • Rapid progression of symptoms and signs should prompt the suspicion of the possible malignant nature of the pathology. (thieme-connect.com)
  • The final pathologic diagnosis was well-differentiated carcinoid tumor of a malignant nature. (springer.com)
  • The aim of this study was to find out the characteristic morphology of malignant atypical cells which were missed on routine cytology of urine. (cytojournal.com)
  • In this present paper we analyzed the characteristic morphology of malignant atypical cells which were missed on routine cytology of urine. (cytojournal.com)
  • Low AKR1B10 expression induces M2 macrophage polarization and promotes the malignant transformation of GC. (portlandpress.com)
  • Conclusions Bcl2 , Myc and Ccnd1 or Bcl2 , Myc and CCND3 synergistically transformed mouse primary B cells into aggressive malignant cells. (haematologica.org)
  • Laboratory and imaging studies gave results that were consistent with a malignant obstruction in the common bile duct. (springer.com)
  • Due to its slow progression, the patient attributes his condition to the ageing process, ignoring its evolutive and malignant nature. (bvsalud.org)
  • L'étude portait sur 20 patients atteints d'un carcinome gastrique, 20 patients souffrant d'une gastrite à H. pylori et 20 personnes en tant que groupe témoin. (who.int)
  • based on experimental infection of patients with malignant disease (9). (cdc.gov)
  • A neuroblastoma (occurring in children over 1 year old) is usually malignant. (medlineplus.gov)
  • Increase of bone marrow lymphocytes in systemic mastocytosis: reactive lymphocytosis or malignant lymphoma? (bmj.com)
  • To clarify the nature (reactive or neoplastic) of lesional, perifocally aggregated lymphocytes in bone marrow infiltrates of systemic mastocytosis (SM), the histopathology of which can resemble malignant lymphoma with focal bone marrow involvement, particularly low grade malignant B cell lymphoma of lymphoplasmacytic immunocytoma subtype, which frequently exhibits increased mast cell (MC) numbers. (bmj.com)
  • Necrosis in the background and necrosed papillae were mostly seen in malignant atypical cells. (cytojournal.com)
  • The comet cells and cells with India ink nuclei (single cells with deep black structure-less nuclei) were only observed in malignant atypical cells. (cytojournal.com)
  • The present study emphasizes that nuclear features such as high N/C ratio, hyperchromasia and chromatin abnormalities are particularly useful for assessing the malignant atypical cells. (cytojournal.com)
  • Results: No difference in antigen expression between normal and malignant endothelial cells (ECs) was found for CD54, CD109, CD137, CD141, CD144 and CXCR7. (researchgate.net)
  • In contrast, B cells from immunocytomas showed light chain restriction and monoclonal rearrangement for IgH, confirming their neoplastic nature. (bmj.com)
  • The histiocytic nature of the cells is demonstrated by a positive result on staining with CD68. (medscape.com)
  • But when skin cells in, say, an individual's mole, become malignant, they readily reactivate Slug and gain the ability to spread - something that other cancers can spend decades trying to do. (scienceblog.com)
  • A malignant melanotic tumor of ganglion cells arising from a thoracic sympathetic ganglion. (thieme-connect.com)
  • However, the malignant nature of these cells remains unknown. (bvsalud.org)
  • 10 Jefferson G. The trigeminal neurinomas with some remarks on malignant invasion of the gasserian ganglion. (thieme-connect.com)
  • Bovine malignant catarrhal fever (BMCF) is a fatal lymphoproliferative disease caused by a group of ruminant gamma herpes viruses including Alcelaphine gammaherpesvirus 1 (AlHV-1) and Ovine gammaherpesvirus 2 (OvHV-2) These viruses cause unapparent infection in their reservoir hosts (sheep with OvHV-2 and wildebeest with AlHV-1), but are usually fatal in cattle and other ungulates such as deer, antelope, and buffalo. (wikipedia.org)
  • The term bovine malignant catarrhal fever has been applied to three different patterns of disease: In Africa, wildebeests carry a lifelong infection of AlHV-1 but are not affected by the disease. (wikipedia.org)
  • Figure from McConnell, The Nature of Disease, 2nd ed. (powershow.com)
  • The findings of previous occupational studies are confirmed, and cadmium exposure is strongly implicated as a cause of certain types of malignant disease. (cdc.gov)
  • Conclusions: The present study shows that CD276 can be used to discriminate ECs from malignant tissue from ECs from normal tissue. (researchgate.net)
  • Thorough investigation of any breast mass is essential to clarify its nature. (hindawi.com)
  • Together our data indicate that PANX1 channels regulate human NB malignant properties and that the use of PBN or CBX may provide a new therapeutic approach for high-risk NB. (jcancer.org)
  • I introduce the idea that from the dawn of human history our species has fallen prey to a collective psychosis which I call malignant egophrenia. (realitysandwich.com)
  • Coexisting foamy and nonfoamy adenocarcinoma with glandular differentiation devoid of basal cell lining is helpful in clarifying their malignant nature. (medscape.com)
  • They will drop off from the cell membrane, as a kind of dissolvable antigen, to be dissolved into the serum, being of sugar protein and mucoglobulin in nature. (qigonginstitute.org)
  • The biopsy will also show whether the tumor is high grade (highly malignant, which is the case for most osteosarcomas) or low grade. (sarcomahelp.org)
  • Dantrolene will also lower an elevated temperature in disorders other than MH, such as thyroid storm, neuroleptic malignant syndrome (NMS), and sepsis. (medscape.com)
  • Based on biological analysis, miR-20b-5p was hypothesized to be a key factor due to the malignant behavior of BCSCs. (researchsquare.com)