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  • transverse colon
  • The lower part of the right half, below the transverse colon, is covered by peritoneum continuous with the inferior layer of the transverse mesocolon, and is in contact with the coils of the small intestine. (wikipedia.org)
  • adenoma
  • CRC develops from normal colon epithelium through an adenoma precursor stage. (springer.com)
  • The length of time required for preinvasive adenoma to progress to carcinoma, the immunogenicity of colorectal cancer (CRC), and the identification of high-risk populations make development and testing of a prophylactic vaccine for the prevention of CRC possible. (aacrjournals.org)
  • We further identified 23 genes that showed protein overexpression in colon adenoma and CRC based on literature review. (aacrjournals.org)
  • markers
  • Patients suffering from high risk stage II colon cancer (CC) may benefit from adjuvant onco-therapy, but additional prognostic markers are needed for better treatment stratification. (springer.com)
  • Furthermore
  • Furthermore, if it is assumed that colon cancer development after Barrett's oesophagus is the result not of Barrett's metaplasia per se, but of common underlying risk factors, there should be an excess risk of oesophageal adenocarcinoma among patients with colon cancer. (bmj.com)
  • Furthermore, GEMMs can only be used to model cancers characterized by one or a few specific genetic mutations, but many cancers, especially hematological malignancies, are caused by large-scale chromosomal rearrangements that cannot be easily replicated in a murine system. (biologists.org)
  • follicular
  • Through these multiple GC reentries, the hallmark BCL2:IGH translocation enables AID-induced hypermutation and propagates clonal evolution toward malignant follicular lymphoma. (jci.org)
  • adenomatous
  • Unfortunately, in the case of colorectal cancer, with the exception of familial multiple adenomatous polyposis coli (FPC), the importance of genetics has been severely neglected. (springer.com)
  • prevalence
  • With the preventive potential of this biologically active agent, we suggest that countries where cancer is on the rise-yet where sunlight and, hence, vitamin D may be easily acquired-adopt awareness, education and implementation strategies to increase supplementation with vitamin D in all age groups as a preventive measure to reduce cancer risk and prevalence. (mdpi.com)
  • progression
  • LSF and Thymidylate synthase plays significant role in Liver Cancer proliferation and progression and Drug resistance. (wikipedia.org)
  • IRS-1, as a signalling adapter protein, is able to integrate different signalling cascades, which indicates its possible role in cancer progression. (wikipedia.org)
  • significantly
  • It is worth noting that the overall survival rate of patients with SRCC was significantly poorer than that of patients with mucinous or poorly differentiated adenocarcinoma. (wikipedia.org)
  • By the time esophageal cancer is usually detected, though, it might have spread beyond the esophageal wall, and the survival rate drops significantly. (wikipedia.org)
  • villous
  • The villous subdivision are associated with the highest malignant potential because they generally have the largest surface area. (wikipedia.org)
  • clonal
  • Clonal expansion is the signature of natural selection in cancer. (wikipedia.org)
  • In the decades that followed, cancer was recognized as having a clonal origin associated with chromosomal aberrations. (wikipedia.org)
  • prevalent
  • Gastrointestinal cancers rank second as a group in the most frequent neoplasias of men and women in the United States and are one of the most prevalent cancers in the world in general (Ajani, Curley et al. (freepatentsonline.com)
  • prostate cancer
  • Prostate cancer (PCa) is the first in terms of occurrence in Europe and second in Poland. (hindawi.com)
  • The prostate-specific antigen (PSA) level may be elevated in prostate cancer or other prostate disorders. (hindawi.com)
  • Prostate cancer is usually suspected on the basis of digital rectal examination (DRE) and/or prostate-specific antigen (PSA) level. (hindawi.com)
  • PSA plays a crucial role in diagnosing prostate cancer [ 1 ]. (hindawi.com)
  • Australia: Warwick Anderson, National Health and Medical Research Council Canada: Thomas Hudson, Ontario Institute for Cancer Research, Susan Langlois, Prostate Cancer Canada and Cindy Bell, Genome Canada China: Henry Yang and Youyong Lu, Chinese Cancer Genome Consortium European Commission: Jacques Remacle, Patrik Kolar and Iiro Eerola France: Fabien Calvo, Institut National du Cancer (INCa) Germany: Axel Aretz and Frank Laplace, Federal Ministry of Education and Research. (wikipedia.org)