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  • squamous cell carc
  • A biopsy may be required to rule out a pigmented basal cell carcinoma or, in the case of an inflamed seborrheic keratosis, squamous cell carcinoma or malignant melanoma. (doctorlib.info)
  • less commonly, squamous cell carcinoma, melanoma, sarcoma, and neuroendocrine tumors can also present with a primary site of origin that cannot be determined. (uchile.cl)
  • neoplasm
  • Brain tumors represent the most common solid neoplasm in children and second most common pediatric malignancy overall, following leukemia. (jaocr.org)
  • Children with medulloblastomas most often present clinically with a relatively rapid onset of symptoms - over the course of weeks or a few months - due to the rapid growth and malignant features of the neoplasm. (jaocr.org)
  • Classification
  • Detailed histopathological classification of tumors from a cohort of patients ( n = 87) composed mainly of children entered into the International Society of Pediatric Oncology (SIOP)/United Kingdom Children's Cancer Study Group PNET3 trial ( n = 65), included identification of the large cell/anaplastic phenotype. (aacrjournals.org)
  • carcinoma
  • The familial tumor syndromes (and respective chromosomal abnormalities that are associated with CNS neoplasms) include neurofibromatosis type I (17q11), neurofibromatosis type II (22q12), von Hippel-Lindau disease (3p25-26), tuberous sclerosis (9q34, 16p13), Li-Fraumeni syndrome (17p13), Turcot syndrome type 1 (3p21, 7p22), Turcot syndrome type 2 (5q21), and nevoid basal cell carcinoma syndrome (9q22.3). (uchile.cl)
  • metastatic
  • They also invade surrounding tissues and are metastatic, initiating the growth of similar tumors in distant organs. (thefreedictionary.com)
  • Metastatic brain tumors. (uchile.cl)
  • Whether primary, metastatic, malignant, or benign, brain tumors must be differentiated from other space-occupying lesions such as abscesses, arteriovenous malformations, and infarction, which can have a similar clinical presentation. (uchile.cl)
  • Of all patients with brain tumors, 70% with primary parenchymal tumors and 40% with metastatic brain tumors develop seizures at some time during the clinical course. (uchile.cl)
  • Together with metastatic tumor at presentation, the large cell/anaplastic phenotype, 17p13.3 loss, or high-frequency MYC amplification defined a high-risk group of children whose outcome was significantly ( P = 0.0002) poorer than a low-risk group without these tumor characteristics. (aacrjournals.org)
  • Biopsy
  • When these results do not reveal signs of a potential primary lesion and the biopsy is not consistent with a primary tumor at the biopsy site, a CUP must be assumed. (uchile.cl)
  • neural
  • Someauthors proved that this tumor causes a high urinaryexcretion of vanillylmandelic acid (VMA), suggestinga neural crest origin. (blogspot.com)
  • An important gene associated with Bednar Tumor is PDGFB (Platelet Derived Growth Factor Subunit B), and among its related pathways/superpathways are Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers . (malacards.org)
  • 76 Ganglioneuroma is a rare and benign tumor of the autonomic nerve fibers arising from neural crest. (malacards.org)
  • pituitary
  • Hormonal deficiencies may result as the tumor interrupts the pituitary stalk or destroys the hypothalamus. (thedoctorsdoctor.com)
  • INTERVENTION: The patient underwent a right frontotemporal craniotomy with total resection of the suprasellar tumor, which was dissected from the pituitary stalk. (thedoctorsdoctor.com)
  • Diagnosis
  • In all cases, the clinical features must be correlated with the distinctive microscopic appearance of the tumor to confirm or exclude the diagnosis on the basis of physical examination. (doctorlib.info)
  • incidence
  • Available registry data from the Surveillance, Epidemiology, and End Results (SEER) database for 1996 to 2000 indicate that the combined incidence of primary invasive CNS tumors in the United States is 6.6 per 100,000 persons per year with an estimated mortality of 4.7 per 100,000 persons per year. (uchile.cl)
  • In general, the incidence of primary brain tumors is higher in whites than in blacks, and mortality is higher in males than in females. (uchile.cl)
  • congenital
  • CONCLUSION: This case suggests a possible link in the adult patient between the growth of this supposedly congenital tumor and hormonal stimulation. (thedoctorsdoctor.com)