• In the case of an existing tumour, a biopsy would be then required to make a diagnosis and distinguish whether the tumour is malignant or benign. (wikipedia.org)
  • Despite advances in surgical techniques and multimodal treatment regimens with radio-, chemo-, and immunotherapy [ 3 - 5 ], the prognosis for malignant glioma patients is very poor with a median survival time of approximately 15 months after diagnosis [ 6 , 7 ]. (hindawi.com)
  • The postmortem diagnosis of malignancy was made histologically on formalin-fixed tissue. (thieme-connect.de)
  • In these cases attempts were made to find out if the initial diagnosis of malignancy had been made before death. (thieme-connect.de)
  • This may be due to late diagnosis of these tumors in our patients as most cases diagnosed at advanced stage and the sections were taken from deep tumor tissue to increase the number of tumor cells in our samples. (researchgate.net)
  • 1 Early diagnosis of a cardiac tumor is often difficult because patients typically do not experience symptoms until late in the disease process. (acc.org)
  • On the basis of characteristic cytological features, a diagnosis of metastatic neuroendocrine tumor/paraganglioma was suggested. (cytojournal.com)
  • A preoperative diagnosis of a primary malignant ovarian tumour was made. (annals.edu.sg)
  • A pedunculated, subserosal uterine leiomyoma with extensive cystic degeneration can mimic an ovarian tumour on imaging and should be considered in the differential diagnosis of an adnexal mass. (annals.edu.sg)
  • Its metastatic potential depends on the phenotype of the tumor cells, and it frequently disseminates before diagnosis. (medscape.com)
  • Abstract-The use of quantitative imaging for the characterization of hepatic tumors in MRI can improve the diagnosis and therefore the treatment of these life-threatening tumors. (sciweavers.org)
  • Background: The development of effective frameworks that permit an accurate diagnosis of tumors, especially in their early stages, remains a grand challenge in the field of bioinf. (sciweavers.org)
  • Knowledge of the expression patterns of HE4 in our survey is useful for application in histopathologic diagnosis, and should be taken into consideration in future studies that examine the role of HE4 as a serological tumor biomarker or as a target for gene-based therapy. (nature.com)
  • We discuss the implications of our results in terms of the potential role for HE4 in histopathologic diagnosis, as a serum tumor biomarker, and as a therapeutic target. (nature.com)
  • Although researchers have learned much from the study of this diverse group of tumors over the years, the diagnosis and treatment of salivary gland neoplasms remain complex and challenging problems for the head and neck surgeon. (medscape.com)
  • Successful diagnosis and treatment of patients with salivary gland tumors require a thorough understanding of tumor etiology, biologic behavior of each tumor type, and salivary gland anatomy. (medscape.com)
  • She was taken for exploratory laparotomy with provisional diagnosis of malignant ovarian tumor. (scirp.org)
  • However, certain malignancies do have characteristic or highly suggestive findings to aid in diagnosis. (oncolink.org)
  • Tumor markers are tumor-derived or tumor-associated proteins, antigens, genes or hormones that can also aid in diagnosis, in the measurement of therapeutic response, in locating tumor origin or in determining recurrence. (oncolink.org)
  • Because only a few thyroid nodules can develop into malignancy, making an unnecessary diagnosis affects patient health, and thus national incidence figures. (sundayvision.co.ug)
  • Currently, there are risk factors in the Puerto Rican population, such as obesity and insulin resistance, "because this can increase the likelihood of developing malignancies, however, it is recommended that the health system be used for early diagnosis," the specialist commented. (sundayvision.co.ug)
  • The patented technology involves synthesizing lanthanide (rare earth metal) for use with MRIs to increase the image contrast between a malignant tumour and surrounding tissue for more accurate and effective diagnosis and surgery. (uvic.ca)
  • Although the mortality rate is decreased due to early diagnosis, the survival rate varies depending on the type of tumor. (peerj.com)
  • No significant difference in tumor size (p= 0.405) and age at diagnosis (p=0.225) was found between the two groups, suggesting that surveillance bias does not adequately explain the excess thyroid cancer risk alone. (cdc.gov)
  • This study aimed to report and discuss the challenging differential diagnosis between a primary tumor of sweat glands and cutaneous metastasis of mammary carcinoma using anatomopathological and imaging diagnostic resources available today. (bvsalud.org)
  • The purpose of this project is to develop and evaluate three non-invasive examination methods for the diagnosis of breast tumors, namely photoacoustics, diffuse reflectance spectroscopy and ultrasound-based tissue characteristics. (lu.se)
  • Benign lesions in children represent 30% of hepatic tumors and are most commonly vascular in origin (eg, hemangiomas, hemangioendotheliomas). (medscape.com)
  • Collagen VI (COL6) is highly expressed in adipose tissue, upregulated in the obese state, and enriched in breast cancer lesions and is a stimulator of mammary tumor growth. (jci.org)
  • The most obvious value of DNA flow cytometry in salivary gland tumours is thus its contribution to assist histopathology in identifying potentially malignant lesions. (researchgate.net)
  • Imaging findings suggestive of malignancy are tumor invasion, right-sided lesions, and an associated pericardial effusion. (acc.org)
  • Patients with malignant lesions typically present after age 60 years, whereas those with benign lesions usually present when older than 40 years. (medscape.com)
  • In addition, the investigators found that 0.15% of the lesions underwent malignant transformation. (medscape.com)
  • the doctor Jose Garcia Mateo the former president of Puerto Rican Endocrinology and Diabetes Association warned that overdiagnosis From thyroid cancer They should be avoided, because once nodules are detected, the first option is to use aggressive treatments when research indicates that less than 10% of these lesions are malignant. (sundayvision.co.ug)
  • however, the true incidence of glomus tumors is unknown, likely as a result of misdiagnosis of many of these lesions as hemangiomas or venous malformations. (medscape.com)
  • Malignant tumors of the salivary glands are rare, comprising from 1 to 6% of all head and neck tumors and the parotid is most commonly affected, accounting for 70% of the lesions 1 . (bvsalud.org)
  • The presence of painful symptoms is more common in cases of lesions with malignant characteristic, but asymptomatic malignant tumors of minor salivary glands are not uncommon either 7 . (bvsalud.org)
  • Primary malignant neoplasms of the sweat glands are rare, constituting less than 1% of all primary malignant skin lesions 1 . (bvsalud.org)
  • This yields a relative low rate for hepatic tumors (1.3% of all pediatric malignancies in children under the age of 19 years of age). (medscape.com)
  • Malignancy in cancers is characterized by anaplasia, invasiveness, and metastasis. (wikipedia.org)
  • Motivation: Tumorigenesis is an evolutionary process by which tumor cells acquire sequences of mutations leading to increased growth, invasiveness, and eventually metastasis. (sciweavers.org)
  • We hypothesize that tumor-derived exosomes endow the fibroblasts in tumor microenvironment with invasive phenotype to the benefit of tumor metastasis. (dovepress.com)
  • It is confirmed that large variety of miRNAs in exosomes play important roles in tumor metastasis and invasion. (dovepress.com)
  • It unlocks novel dimensions by uncovering elusive cell populations and tumor heterogeneities for early detection, unraveling mechanisms of treatment resistance, tailoring therapies to individuals, and illuminating metastasis and cachexia pathways, thereby opening fresh avenues for preventive strategies. (frontiersin.org)
  • Esophageal cancer is a malignant disease with a poor prognosis and is one of the most common causes of cardiac metastasis. (bvsalud.org)
  • The incidence of primary malignant liver tumors per year is approximately 1.5 per million children in the United States. (medscape.com)
  • Malignant gliomas are the most common primary malignant brain tumors with an increasing incidence of up to nine per 100,000 habitants over the last years [ 1 , 2 ]. (hindawi.com)
  • Thus, treatment with L-Glu-L-Trp delayed aging rate and decreased spontaneous tumor incidence in rats. (nih.gov)
  • Liposarcoma , a malignancy of fat cells, is the most common soft tissue sarcoma with an annual incidence of 2.5% cases per million. (drrathresearch.org)
  • [ 1 ] The incidence of salivary gland neoplasms as a whole is approximately 5.5 cases per 100,000 individuals in the United States, with malignant neoplasms accounting for 0.9 cases per 100,000. (medscape.com)
  • That is, as the size of the gland decreases, the incidence of malignancy of a tumor in the gland increases in approximately these proportions. (medscape.com)
  • 1% of all Gastrointestinal (GI) tumors and its incidence is approximately 10 - 20 per million people per year. (scirp.org)
  • Decrease the incidence of infection, as manifested by febrile neutropenia, in patients with non-myeloid malignancies receiving myelosuppressive anti-cancer drugs associated with a clinically significant incidence of febrile neutropenia. (drugs.com)
  • All samples tested were confirmed to be malignant, suggesting that overdiagnosis by virtue of misdiagnosis of a benign tumor as malignant does not explain the increased incidence of thyroid cancer observed in WTC responders. (cdc.gov)
  • These effects were partially mediated through enhanced TGF-β signaling, which contributes to tissue fibrosis and epithelial-mesenchymal transition (EMT) of tumor cells. (jci.org)
  • Methods: Flow cytometric analysis of DNA pliody and S-Phase Fraction (SPF) was done in 50 fresh tumor tissue sections of SGTs which diagnosed as 15 benign and 35 malignant tumors. (researchgate.net)
  • 3 Pericardiocentesis typically yields bloody or necrotic tissue, yet cytology is nearly always negative for malignancy, even in the setting of pericardial infiltration. (acc.org)
  • 4,5 Cardiac CT is utilized as a supplement to echocardiography, and cardiac MRI is utilized for tissue characterization and in the analysis of tumor infiltration. (acc.org)
  • Synovial sarcoma is a malignant soft-tissue neoplasm that most commonly affects the extremities near to, but not in continuity with, large joints. (medscape.com)
  • Benign musculoskeletal neoplasms are one hundred times more common than malignant soft tissue tumors. (drrathresearch.org)
  • The ocular tissue where these tumors arise, the uvea, is a densely pigmented layer that lies for the most part between the sclera and the retina. (medscape.com)
  • Here, we examined the expression of the HE4 gene and protein in a large series of normal and malignant adult tissues by oligonucleotide microarray and tissue microarray, respectively. (nature.com)
  • Here, we used oligonucleotide and tissue microarrays to survey HE4 gene and protein expression in a large group of malignant and normal tissues from adults. (nature.com)
  • 10 High expression of miR-21 in melanoma cells inhibits mRNA expression of crucial tumor suppressor proteins such as the tissue inhibitor of metalloproteinases 3 (TIMP3). (dovepress.com)
  • Deep en-bloc biopsies of the same tissue are often reported correctly as tumors. (merckvetmanual.com)
  • The primary objectives in a diagnostic evaluation for suspected cancer are determinations of the tissue type, the primary site of malignancy, the extent of disease within the body and the tumor's future recurrence potential. (oncolink.org)
  • Severe inflammation in a tumor, necrosis of tissue in a tumor, or inadequate biopsies can result in a "false negative" report. (vin.com)
  • The first is determining the tissue of origin, the second is differentiating among inflammation, hyperplasia/benign tumor and malignant tumor, and the third is classifying the inflammatory process or the tumor. (vin.com)
  • Following injection prior to an MRI, the nanoparticles will not only inform a surgeon as to the location of a tumour but also provide a better image of its shape, which helps surgeons determine how much surrounding tissue needs to be removed," says van Veggel. (uvic.ca)
  • Glomus tumors are rare soft tissue neoplasms that typically present in adults (ages 20-40 years) as small, blue-red papules or nodules of the distal extremities, with most cases involving subungual sites. (medscape.com)
  • For aim 2, 30 patients with available thyroid tumor tissue samples were matched with 30 non-WTC thyroid cancer patients on age, sex, and histology and were evaluated using established cancer-detection four-biomarker panel of malignancy to determine the false positive rate for malignancy. (cdc.gov)
  • 1a) Can one distinguish between benign and malignant tissue? (lu.se)
  • Our hypothesis is that the functional and molecular information, for example, oxygen saturation of suspected tumor tissue, may be a discriminating factor between benign and malignant tissue. (lu.se)
  • b) What other quantitative factors can be a discriminating factor between benign and malignant tumor tissue? (lu.se)
  • Proton beam therapy offers a high degree of precision, allowing an escalated radiation dose to be targeted directly on a tumor while sparing the adjacent healthy tissue. (medscape.com)
  • Of these malignant tumors, hepatoblastoma (HB) and hepatocellular carcinoma (HCC) are the most common and account for over two thirds of all hepatic neoplasms. (medscape.com)
  • AFP levels are elevated in 50-70% of children with hepatic neoplasms, and multiple studies confirm that AFP is a valuable surveillance marker in children who have previously undergone hepatic resection for malignancy. (medscape.com)
  • Aim: The aim of this study is to investigate the DNA ploidy and S-Phase Fraction (SPF) of some Salivary Gland Tumors (SGTs) in Egyptian patients and to investigate the correlation between these two biological parameters and the presumptive behavior of these neoplasms. (researchgate.net)
  • Nonmesotheliomatous cancers of the pleura include an assortment of malignant neoplasms that primarily or secondarily involve pleura. (medscape.com)
  • Neoplasms that arise in the salivary glands are relatively rare, yet they represent a wide variety of both benign and malignant histologic subtypes as seen in the image below. (medscape.com)
  • Salivary gland neoplasms make up 6% of all head and neck tumors. (medscape.com)
  • [ 4 , 5 ] ) Benign neoplasms occur more frequently in women than in men, but malignant tumors are distributed equally between the sexes. (medscape.com)
  • Most series report that about 80% of parotid neoplasms are benign, with the relative proportion of malignancy increasing in the smaller glands. (medscape.com)
  • The most common tumor of the parotid gland is the pleomorphic adenoma , which represents about 60% of all parotid neoplasms, as seen in the table below. (medscape.com)
  • Almost half of all submandibular gland neoplasms and most sublingual and minor salivary gland tumors are malignant. (medscape.com)
  • In children, 35% of salivary gland neoplasms are malignant. (medscape.com)
  • Contrasting information was derived through a literature review by Louredo et al, which indicated that in pediatric patients, most salivary gland neoplasms (75.4%) are malignant. (medscape.com)
  • GISTs (Gastrointestinal stromal tumors) are most common mesenchymal neoplasms of gastrointestinal tract. (scirp.org)
  • There are between 450 and 750 minor salivary glands distributed in the head and neck area4 and neoplasms affecting these structures are usually malignant. (bvsalud.org)
  • A register-based case-control study on cellular telephone use and brain tumors and salivary gland cancers was conducted in Finland. (emf-portal.org)
  • The results showed no association between brain tumors or salivary gland cancers and the use of cellular phone . (emf-portal.org)
  • At the same time, inflammatory cells can also interact with malignant cells to form an inflammatory tumour microenvironment. (wikipedia.org)
  • Once this occurs, the inflammatory tumour microenvironment begins to send out tumour-promoting signals to epithelial cells, triggering the formation of malignant cells. (wikipedia.org)
  • Adipocytes represent a major cell type in the mammary tumor microenvironment and are important for tumor growth. (jci.org)
  • Adipocyte-derived factors involved in tumor progression include proteins such as adiponectin, leptin, TNF-α, monocyte chemotactic protein-1 (MCP-1), IL-6, and ECM components that control tumor cell behavior within the tumor microenvironment. (jci.org)
  • In the metabolic symbiosis model, these cells have been proposed to overexpress MCT4 to release high amounts of lactate produced during anaerobic glycolysis into the tumor microenvironment. (hindawi.com)
  • 2 , 3 Tumor cell-derived exosomes carry particular molecular components originated from donor cells to mediate tumorigenesis and drive tumor progression by regulating tumor microenvironment. (dovepress.com)
  • Regardless of the therapeutic approach, the heterogeneity of pancreatic cancer cells and the complexity of its tumor microenvironment contribute to the emergence of drug resistance. (frontiersin.org)
  • Viral agents are able to assist the formation of malignant tumours due to a mechanism of cell transformation. (wikipedia.org)
  • This study on 279 tumours of the salivary glands was conducted to analyse whether the assessment of DNA ploidy by flow cytometry may assist histopathology in discriminating benign from malignant types of tumours. (researchgate.net)
  • The malignant tumours consisted of 18 adenoid cystic adenomas, 10 mucoepidermoid carcinomas, 5 acinic cell carcinomas, 5 carcinoma in pleomorphic adenoma as well as of 12 other malignancies belonging to 7 different tumour entities. (researchgate.net)
  • Twelve of 50 malignant salivary gland tumours were aneuploid. (researchgate.net)
  • More aggressive tumours have low T 1 - and T 2 -characteristics while high signal is observed on both T 1 - and T 2 -weighted images if there has been recent haemorrhage within the tumour. (ispub.com)
  • For this reason, the CD-ROM accompanying malignant vascular tumours. (who.int)
  • There was no significant correlation of ploidy status or SPF with the tumor grades of mucoepidermoid carcinomas. (researchgate.net)
  • In a series of 175 human adult tumors, gene expression was highest in ovarian serous carcinomas. (nature.com)
  • They performed comparative studies of the cutaneous malignancy and breast nodules, especially with immunohistochemical examinations. (bvsalud.org)
  • Tumor-derived exosomes are messengers that participate in tumor progression. (dovepress.com)
  • Our results suggest that tumor-derived exosomes may facilitate stromal fibroblasts an aggressive phenotype to equip the tumor progression. (dovepress.com)
  • Molecular genetics and immunopathologic analysis of bladder cancer have shown some abnormalities in a number of genes and proteins that have been implicated in the development and progression of such tumors, mainly in the p53 pathway. (ijpmonline.org)
  • Preoperative work up included upper GI endoscopy and biopsy, CT abdomen (digital angiography in cases with suspected vascular invasion), Tumour markers and assessment of fitness for surgery. (sages.org)
  • Our results suggest that a micronutrient mixture containing vitamin C, EGCG, Lysine, Proline and other natural components is effective in inhibiting cancer cells proliferation, secretion of MMPs and cancer invasion through Matrigel in vitro and in inhibiting the tumor growth of grafted saracoma cell lines in nude mice. (drrathresearch.org)
  • Role of tumor-derived exosomal miR-21 in cell invasion was determined by qPCR. (dovepress.com)
  • 8 , 9 The high-invasion and metastatic tendency of melanoma tumors complicates treatment of the malignancy. (dovepress.com)
  • CT or MRI may be very useful in assessing the tympanic bulla more completely and in determining the extent of tumor invasion, especially in malignant tumors. (merckvetmanual.com)
  • On clinical presentation, features like facial weakness, pain and paresthesia hint towards invasion by a malignant tumour. (ispub.com)
  • Malignant mixed tumour, on the other hand, is characterized by perivascular and perineural invasion, significant cellular atypia and mitosis( 2 ). (ispub.com)
  • Osteosarcoma accounts for about 60% of malignant bone tumors between the ages of 10 to 20. (drrathresearch.org)
  • We study this phenomenon in osteosarcoma, a childhood malignancy that harbors one of the most rearranged genomes in cancer. (lu.se)
  • These tumors occasionally present a pelvic mass and lead to the misdiagnosis of gynecologic diseases. (scirp.org)
  • It is often used for detecting ascites, biliary or renal obstruction, or pelvic tumors, and is also useful for guiding biopsies. (oncolink.org)
  • Malignancy arising in mixed tumors of the salivary gland is a distinct entity that can occur sporadically or in association with a background of pleomorphic adenoma. (ijpmonline.org)
  • We report 23 cases of tumors of the salivary gland comprising 18 cases of carcinoma ex pleomorphic adenoma, four cases of carcinosarcoma of the parotid and one case of benign metastasizing pleomorphic adenoma. (ijpmonline.org)
  • It's my pleasure to be with you today and to discuss with you some advanced cases of tumors within the paranasal sinuses. (brainlab.com)
  • This brain tumor type is highly proliferative and shows an infiltrative growth pattern, accounting for the high recurrence rates in patients. (hindawi.com)
  • The most common cause of hypercalcemia in hospitalized patients is malignancy. (hindawi.com)
  • Abstract--A deformable registration method is proposed for registering a normal brain atlas with images of brain tumor patients. (sciweavers.org)
  • Considering that only few patients with gastrointestinal stromal tumors have been reported in the obstetrical and gynecological literature, the awareness of such an entity by the obstetricians-gynecologists is necessary in order to facilitate coordinated approach with the general surgeons and oncologists for the optimal care of the patients. (scirp.org)
  • Biopsy methods for accurate histologic or cytologic proof of malignancy are absolutely essential to workup and subsequent management of suspected cancer patients. (oncolink.org)
  • Nail SCC rarely metastasizes, and when it does, it is more common in poorly differentiated tumors and immunosuppressed patients. (logicalimages.com)
  • Chondrosarcoma is the most common primary malignant bone tumor in patients older than 25 years [ 35 ]. (lww.com)
  • Although intermediate- and high-grade tumors have a survival rate of 40% to 60%, low-grade tumors result in long-term survival in as much as 90% of patients [ 11, 13, 14, 18, 20, 37 ]. (lww.com)
  • 2 ] The liver is the primary site for metastases for most malignancies of the gastrointestinal tract, accounting for a large proportion of the morbidity and mortality in those patients. (bcmj.org)
  • Surgical resection is the only known potentially curative treatment for patients with primary or metastatic liver tumors. (bcmj.org)
  • The plasma levels of B7-H4 were increased in patients with EOC II compared to those with benign ovarian tumors. (lu.se)
  • Patients with glomus tumors classically present with paroxysmal severe pain, often precipitated by cold, pressure, or dependency. (medscape.com)
  • multiple tumors-classically seen as glomuvenous malformations-arise in younger patients and tend to be asymptomatic. (medscape.com)
  • A Cox proportional hazard model was used to estimate risk of subsequent malignancies in NMSC patients versus controls and to assess the potential confounding effects of multiple risk factors on this risk. (cdc.gov)
  • Our aim is to develop new treatment strategies for patients with highly aggressive malignancies. (lu.se)
  • A malignant tumor contrasts with a non-cancerous benign tumor in that a malignancy is not self-limited in its growth, is capable of invading into adjacent tissues, and may be capable of spreading to distant tissues. (wikipedia.org)
  • Malignancies of the soft tissues (6%) and bone (5%) account for more than 10% of cancers diagnosed in children, adolescents, and young adults. (drrathresearch.org)
  • Erosion of the tumor into blood vessels in adjacent tissues, or areas of necrosis within the tumor, can lead to hyphema or vitreous hemorrhage. (medscape.com)
  • however, the expression in normal and malignant adult tissues has not been examined in detail. (nature.com)
  • Tumors of the Ear Canal in Dogs Tumors may develop from any of the structures lining or supporting the ear canal, including the outer layer of skin, the glands that produce earwax and oil, or any of the bones, connective tissues. (merckvetmanual.com)
  • Because the cytological characteristics of hyperplasia, inflammation, and malignancy can differ in different tissues, it is important to first determine the most frequently occurring type of cell in the cytological preparation. (vin.com)
  • The GSE3467 , GSE3678 , GSE33630 and GSE53157 were obtained from the GEO database, including 100 thyroid tumors and 64 normal tissues to obtain the intersection of differentially expressed genes, and a protein-protein interaction network was constructed to obtain the HUB gene. (peerj.com)
  • We investigated the impact on tumor malignancy in F98 glioma cells using in silico analysis, in vitro cell culture assays, and ex vivo vascular organotypic glioma impact model (VOGIM) [ 35 ] by implanting F98 cells into rat brain slices. (hindawi.com)
  • The remaining bone malignancies in children and adolescents are Ewing sarcomas. (drrathresearch.org)
  • In children and adolescents, salivary gland tumors make up 0.5% of all malignancies. (medscape.com)
  • These disseminated variants of glomus tumor, known as glomangiomas or glomuvenous malformations, differ clinically from glomus tumors in that they occur more often in children and adolescents, are typically multifocal, and do not have a predilection for subungual sites. (medscape.com)
  • S-phase value is correlated with the behavior of the tumors [13, 14]. (researchgate.net)
  • The term fibroma is inappropriate because the neoplasm exhibits defined histologic features that differ from those of fibromas and may express malignant behavior. (medscape.com)
  • In line with this observation, elevated extracellular lactate concentrations up to 40 mM and corresponding low extracellular pH (pH e ) have been found in solid tumors under hypoxic conditions [ 18 - 22 ]. (hindawi.com)
  • Benign liver tumors include hepatocellular adenomas (HCAs), hemangiomas , hamartomas, and focal nodular hyperplasia (FNH). (medscape.com)
  • Most children with liver tumors present with abdominal distension, a palpable abdominal mass, or both. (medscape.com)
  • Hemangiomas are the most common benign liver tumors in children and commonly occur within the first 6 months of life. (medscape.com)
  • RESULTS: The levels of suPAR(II-III), HE4, CA125 were all higher in EOC II than in EOC I, borderline and benign ovarian tumors. (lu.se)
  • B7-H4 was increased in EOC II compared with benign ovarian tumors. (lu.se)
  • CONCLUSION: The biomarker panel suPAR(II-III), HE4, CA125 and age in premenopausal women improved discrimination of malignant and benign ovarian tumors. (lu.se)
  • Sometimes, for example in endocrine tumors, the cytoplasm is stripped from the nucleus when the smear is streaked out and there are mostly naked nuclei. (vin.com)
  • Primary carcinoma of the fallopian tube is a rare neoplasm, accounting for only 0.3-1.1% of all gynecological malignancies [1]. (amrita.edu)
  • This was a retrospective study of histopathological confirmed gynecological malignancies conducted in the department of oncology from January 2016 to December 2021. (bvsalud.org)
  • Colorectal cancer (CRC) metastases and other malignant tumors of the liver result in significant cancer-related mortality in British Columbia and worldwide. (bcmj.org)
  • Metastases tend to have more tightly packed cellular architecture, which may cause uneven ethanol distribution, resulting in incomplete tumor necrosis. (bcmj.org)
  • We herein report a case of malignant pericarditis in a patient with metastatic esophageal squamous cell carcinoma with cardiac tamponade, which was successfully managed with single pericardial drainage and systemic nivolumab monotherapy. (bvsalud.org)
  • Apart from the possibility of poor quality of the biopsy, cytology has another limiting factor as mentioned earlier: a negative (e.g., tumor-negative) report is less reliable than a positive report. (vin.com)
  • This is not nearly as accurate as a biopsy when it comes to distinguishing benign from malignant thyroid disease but greater than 90% of the time this procedure will at least identify the growth as thyroid in origin. (vin.com)
  • If malignancy is suspected or demonstrated by biopsy, imaging studies should be done. (msdmanuals.com)
  • This paper describes a case of a 71-year-old female who initially went to a dermatologist to assess a scalp skin tumor, which performed an incisional biopsy. (bvsalud.org)
  • The two red spots are the salivary glands (which take up i-131) and the large red spot is the tumor. (vin.com)
  • Many malignant tumors of salivary glands are characterized by abundant secretion of mucin. (bvsalud.org)
  • The majority of HHM is caused by tumor-produced parathyroid hormone-related protein and less frequently production of 1,25-dihydroxyvitamin D or parathyroid hormone by the tumor. (hindawi.com)
  • Malignant tumors are also characterized by genome instability, so that cancers, as assessed by whole genome sequencing, frequently have between 10,000 and 100,000 mutations in their entire genomes. (wikipedia.org)
  • Cancers usually show tumour heterogeneity, containing multiple subclones. (wikipedia.org)
  • Accurate lung tumor targeting in real time plays a fundamental role in image-guide radiotherapy of lung cancers. (sciweavers.org)
  • L'objectif de cette étude était de déterminer la fréquence des cancers gynécologiques en pratique oncologique à Lomé et d'en étudier les aspects épidémiologiques et histo-cliniques. (bvsalud.org)
  • Il s'agitd'une étude rétrospective et descriptive portant sur tous les cancers gynécologiques reçus en oncologie entre le 1erJanvier 2016 et le 31 Décembre 2021. (bvsalud.org)
  • ces cancers ont ete diagnostiques au stade avance d'ou les difficultes dans leur prise en charge chirurgicale. (bvsalud.org)
  • En consequence notre objectif a ete d'etudier la place et les caracteres de la chirurgie dans la prise en charge de ces cancers. (bvsalud.org)
  • The non melanoma skin cancers (NMSC) are the most frequently diagnosed malignancies in the United States [1] with an estimated 900,000 to 1,200,000 new cases diagnosed each year. (cdc.gov)
  • Malignant tumors of the duodenum are extremely uncommon. (sages.org)
  • The occurrence of various malignancies suggests that this phenomenon is not very uncommon and should be looked for when reporting a mixed tumor. (ijpmonline.org)
  • Does cell phone use increase the chances of parotid gland tumor development? (emf-portal.org)
  • The gross pathology was ulcerating mass with stricture in 5 cases, mass in 2 cases and multiple nodules in one case while the microscopic type was adenocarcinoma in 7cases and Neuroendocrine tumor in one case. (sages.org)
  • Besides, upregulated MCT4 has been linked to altered tumor metabolism as well as to increased growth and survival in breast and pancreatic cancer [ 33 , 34 ]. (hindawi.com)
  • However, there has only been one previous functional study investigating MCT4 in glioblastoma (GBM) neurospheres, mainly focusing on tumor growth and survival dependent on the oxygen level [ 14 ]. (hindawi.com)
  • The effect of dipeptide on survival, life span and spontaneous tumor development was studied in female rats. (nih.gov)
  • Treatment results, survival, the occurrence of late complications, and second malignant tumors (SMT) were investigated. (uni-muenchen.de)
  • Median survival time for animals with malignant ear canal tumors has been reported to be >58 months in dogs and >11.7 months in cats. (merckvetmanual.com)
  • Our results highlight the crucial role of ETP as an obesity-associated factor that promotes tumor growth in the context of adipocyte interactions with tumor and stromal cells. (jci.org)
  • Background: Gastrointestinal stromal tumors (GIST) are rare mesenchymal tumors that may mimic ovarian tumor on presurgical testing. (scirp.org)
  • Case Report: We reported a case of 55-year-old post menopausal woman who presented to us as ovarian mass which turned out to be malignant epithelioid gastrointestinal stromal tumor intraoperatively and by immunohistochemistry. (scirp.org)
  • Our case was also presented as ovarian mass which turned out to be malignant epithelioid gastrointestinal stromal tumor intraoperatively and by immunohistochemistry. (scirp.org)
  • Histologically the tumor showed the mass to be a malignant epitheioid gastrointestinal stromal tumor with mitoses in 8 - 9 of 10 high-power fields ( Figure 1 ). (scirp.org)
  • One case received neoadjuvant chemotherapy with impressive tumour regression that enables surgical excision. (sages.org)
  • Surgical excision is possible and could be curative provided the tumour is resectable in case of primary duodenal malignancy. (sages.org)
  • She underwent surgery, and resection of the tumor with neck dissection was performed, which was reported as malignant carotid body paraganglioma on histopathology. (cytojournal.com)
  • Surgical removal of benign ear canal tumors may be accomplished via lateral ear canal resection for access to the tumor mass. (merckvetmanual.com)
  • Lateral ear canal resection for malignancies results in a >75% recurrence rate. (merckvetmanual.com)
  • The mean final Musculoskeletal Tumor Society functional scores were greater after extended intralesional versus resection treatment (29.5 versus 25.1). (lww.com)
  • The liver is the third most common site for intra-abdominal malignancy in children, following adrenal neuroblastoma and renal tumors, such as Wilms tumor . (medscape.com)
  • Tumors secreting PTHrP cause increased bone resorption and distal renal tubular calcium reabsorption. (hindawi.com)
  • Several mechanisms lead to hypercalcemia in malignancy-direct osteolysis by metastatic disease or, more commonly, production of humoral factors by the primary tumor also known as humoral hypercalcemia of malignancy that accounts for about 80% of malignancy-related hypercalcemia. (hindawi.com)
  • Hemangiosarcomas are locally invasive and multicentric ( having two or more primary tumors ). (ivis.org)
  • Only 25% of primary cardiac tumors are malignant, 75% of which are sarcomas. (acc.org)
  • Angiosarcoma is the most common primary cardiac malignancy, composing one-third of cases. (acc.org)
  • The most common category of nonmesotheliomatous cancer to involve the pleura is represented by extrapleural primary malignancies that secondarily involve the pleura via metastatic spread. (medscape.com)
  • We report an unusual case of a large cystic, pedunculated uterine leiomyoma mimicking a primary malignant ovarian tumour on sonography and computed tomography (CT). (annals.edu.sg)
  • Ciliary body melanoma is a subtype of uveal melanoma, the most common primary malignant tumor of the eye. (medscape.com)
  • Uveal melanomas are the most common primary intraocular malignancies and the second most common type of primary malignant melanoma in the body. (medscape.com)
  • Ultrasound uses sound waves to image the deeper structures of the throat and determine the feasibility of removing the primary tumor. (vin.com)
  • The findings show the challenge in differentiating a primary tumor of the sweat gland from a metastatic cutaneous tumor of mammary carcinoma, even with the immunohistochemical resources currently available. (bvsalud.org)
  • The distinction among these various tumors is important both clinically and epidemiologically. (medscape.com)
  • Ewing sarcomas are histologically similar and identical to peripheral primitive neuroectodermal tumors. (drrathresearch.org)
  • 27.2 % of all malignant tumors (141/519) were discovered during the post-mortem examination. (thieme-connect.de)
  • Of these 271 tumors 17 % (46/271) were discovered only during the forensic post-mortem examination. (thieme-connect.de)
  • On microscopic examination, the smears were cellular and showed many loose cohesive clusters and dispersed tumor cells in a background of abundant reactive lymphoid cells and hemorrhage [Figure 1a and b ]. (cytojournal.com)
  • The tumor is usually detected when someone, usually either the owner at home or the veterinarian during the examination, notices a lump around the dog's throat. (vin.com)
  • The initial assessment of a dog with a throat lump should include a physical examination, a basic database of blood and urine testing including a T4 level, and a set of chest radiographs (x-rays) to check for obvious tumor spread. (vin.com)
  • Adults and adolescents must undergo nasopharyngeal examination to exclude malignant or benign tumors. (msdmanuals.com)
  • Pre-clinical and mechanistic studies support that 5-Azacitidine may modulate pathways that enable birinapant-mediated anti-tumor activity. (mayo.edu)
  • Clinical case description of a papillary mucinous cystadenocarcinoma, extremely rare malignant tumor in the salivary gland and difficult to diagnose, in geriatric patient. (bvsalud.org)
  • Patient with 86 years old was referred for treatment with nodular lesion on the inner side of left lower lip extending to the bucal mucosa, without any clinical appearances of malignancy. (bvsalud.org)
  • Malignant pericarditis may cause the repetitive accumulation of pericardial effusion, which can occasionally pose a clinical challenge. (bvsalud.org)
  • Recent research has expanded our understanding of the types of malignancies and clinical scenarios where proton beam therapy is most advantageous. (medscape.com)
  • To this end, we screen clinical tumor material for disease-causing mutations using deep sequencing technology and we manipulate genes of interest in cancer model systems to understand the true consequences of mutations. (lu.se)
  • Lung cancer is a disease in which certain cells in the lungs become abnormal and multiply uncontrollably to form a tumor . (medlineplus.gov)
  • These changes allow cells to grow and divide uncontrollably to form a tumor . (medlineplus.gov)
  • When malignant cells form, symptoms do not typically appear until there has been a significant growth of the mass. (wikipedia.org)
  • Malignant cells often evolve due to a combination of reasons rather than one definitive reason. (wikipedia.org)
  • Infectious diseases play a role in the development of malignancy, with agents of infectious disease being able to produce a multitude of malignant cells. (wikipedia.org)
  • This environment increases the likelihood of forming malignant cells through blockage of anti-tumour immunity. (wikipedia.org)
  • In summary, our data highlight MCT4 /SLC16A3 as a key gene for distinct hallmarks of tumor malignancy in glioma cells. (hindawi.com)
  • This process enables tumor cells, including those within the core of the heterogeneous tumor mass to survive, despite being at a distance from blood vessels that supply their metabolic needs [ 16 , 17 ]. (hindawi.com)
  • Liposarcomas are malignant tumors of the lipocytes ( fat cells ) and are not commonly found in pet birds. (ivis.org)
  • The tumor cells were arranged in focal acinar or follicular pattern with a round-to-oval nucleus, moderate anisonucleosis, fine nuclear chromatin, and moderate-to-abundant fragile cytoplasm with the focal presence of fine granules. (cytojournal.com)
  • Few bizarre and binucleated tumor cells were also noted [Figure 1c and d ]. (cytojournal.com)
  • Tumor-induced glaucoma may be produced by obstruction of outflow pathways by pigment cells (pigment dispersion syndrome), melanin-laden macrophages (melanomalytic glaucoma), or tumor cells. (medscape.com)
  • In brief, frozen sections of profiled tumors were examined by hematoxylin-and-eosin, and areas rich in neoplastic cells were cut from the frozen blocks. (nature.com)
  • So tumor cells-derived exosomes. (dovepress.com)
  • in most cases, we can infer malignancy simply by knowing that the cytology confirmed thyroid cells. (vin.com)
  • Glomus tumors are thought to represent hamartomatous proliferations of modified smooth muscle cells originating from preexisting normal glomus cell populations. (medscape.com)
  • Interestingly, while glomus tumors predominate on the hands and fingers especially, these tumors can occur in a wide anatomic distribution, to include sites not known to contain glomus cells. (medscape.com)
  • One explanation for this finding is that these tumors may arise from perivascular cells that can differentiate into glomus cells. (medscape.com)
  • This theory holds that tumors arise from 1 of 2 undifferentiated stem cells: the excretory duct reserve cell or the intercalated duct reserve cell. (medscape.com)
  • This offers one of the most challenging paradoxes in cancer biology: what is required of a cell to not only survive massive genetic damage but also outcompete neighboring cells and present as a malignant tumor? (lu.se)
  • 2 Becker H. On the frequency and distribution of malignant neoplasm in autopsy material. (thieme-connect.de)
  • By definition, pseudomesotheliomatous carcinoma refers to an epithelial neoplasm that secondarily involves the pleura and encases the lung, thereby simulating the radiologic and macroscopic appearance of malignant mesothelioma. (medscape.com)
  • It is most applicable for malignant disease in the central nervous system, spine, head and neck and musculoskeletal system, aiding in detection, localization and staging. (oncolink.org)
  • Breast cancer is the most common tumor form among women in Sweden and accounts for about 30% of all cancer cases. (lu.se)
  • These tumors are usually asymptomatic, often discovered accidentally during endoscopic or radiologic examinations. (scirp.org)
  • For example, breast cancer that spreads to and forms a metastatic tumor in the lung is metastatic breast cancer, not lung cancer. (healthandenvironment.org)
  • They can be classified as anterior uveal melanomas when the tumor arises in the iris and as posterior uveal melanomas when it arises in either the choroid or the ciliary body. (medscape.com)
  • Moreover, ETP expression was associated with aggressive mammary tumor growth and high metastatic growth. (jci.org)
  • More aggressive surgeries, such as total ear canal ablation and bulla osteotomy, are recommended for malignant tumors of the middle ear. (merckvetmanual.com)
  • Thyroid carcinoma (THCA) is a common endocrine malignant tumor. (peerj.com)
  • Today's story is not about healthy thyroids and their activity but about thyroid malignancy. (vin.com)
  • Thyroid tumor in dogs generally does not affect the production of thyroid hormones. (vin.com)
  • a dog with a thyroid tumor is usually neither hypothyroid nor hyperthyroid. (vin.com)
  • Since statistics indicate a thyroid growth is malignant 87% of the time, this goes a long way to identify it as a thyroid carcinoma. (vin.com)
  • In dogs, there is an 87% chance that a thyroid growth is malignant. (vin.com)