Myelodysplastic SyndromesMyeloproliferative DisordersBone MarrowJanus Kinase 2Primary MyelofibrosisMyelodysplastic-Myeloproliferative DiseasesPolycythemia VeraThrombocythemia, EssentialBone Marrow CellsAnemia, RefractoryBone Marrow NeoplasmsLeukemia, Myelomonocytic, ChronicBone Marrow TransplantationReceptors, ThrombopoietinAnemia, Refractory, with Excess of BlastsLeukemia, Myeloid, AcuteThrombocytosisBone and BonesSyndromeBone Marrow DiseasesLeukemia, MyeloidHematopoietic Stem CellsLeukemia, Myeloid, Chronic, Atypical, BCR-ABL NegativeAnemia, SideroblasticMutationLeukemia, Myelomonocytic, JuvenileHematologic NeoplasmsBone Marrow ExaminationLeukemiaChromosomes, Human, Pair 5Leukemia, Myelogenous, Chronic, BCR-ABL PositiveSplenomegalyProto-Oncogene Proteins c-cblPrognosisKaryotypingHematopoiesisAzacitidineBlast CrisisChromosome AberrationsAnemia, AplasticPhiladelphia ChromosomeBone RemodelingMegakaryocytesTreatment OutcomePreleukemiaMyeloid Progenitor CellsTransplantation, HomologousHematologyPancytopeniaMonosomyHematopoietic Stem Cell TransplantationDNA Mutational AnalysisThalidomideJanus KinasesAntigens, CD34Acute DiseaseCell Transformation, NeoplasticDisease ProgressionSTAT5 Transcription FactorMegakaryocyte Progenitor CellsChromosomes, Human, Pair 7Colony-Forming Units AssayMice, Inbred C57BLNeoplasms, Second PrimaryFlow CytometryBone DensityNeoplasmsMegakaryocyte-Erythroid Progenitor CellsGranulocytesMyelopoiesisCytogenetic AnalysisAntineoplastic AgentsCell ProliferationMutation, MissenseCell DifferentiationClonal EvolutionChromosome DeletionFusion Proteins, bcr-ablBlood Cell CountGranulocyte Precursor CellsBone ResorptionWhole-Body IrradiationBone NeoplasmsHematologic DiseasesErythropoietinSurvival AnalysisCytogeneticsGranulocyte Colony-Stimulating FactorImmunophenotypingProto-Oncogene ProteinsPhenotypeProtein Kinase InhibitorsTransplantation, AutologousRetrospective StudiesTranslocation, GeneticGraft vs Host DiseaseGene Knock-In TechniquesAmino Acid SubstitutionPoint MutationBone Marrow Purging