• Adult male C57BL/6J mice received 25-nm AgNP (100 or 500 mg/kg) once IN. (cdc.gov)
  • MAIN METHODS: Adult male C57BL/6J mice received a subchronic exposure to corticosterone (CORT) at levels mimicking high physiological stress followed by exposure to the sarin surrogate, diisopropyl fluorophosphate (DFP). (cdc.gov)
  • All of the F2 animals are males and all F1s came from B6 females crossed with DBA/2 males. (jax.org)
  • Males and Females. (taconic.com)
  • You ordered twelve males and twelve females, I needed six males and eighteen females. (taconic.com)
  • I need C57BL/6NTac mice, six males and eighteen females. (taconic.com)
  • Five each of young C57BL/6J males and females, and B6.CAST-+Ahl males were exposed to a 4-kHz octave band of noise at 108 dB SPL for 4 h. (cdc.gov)
  • The congenic B6.CAST-+Ahl male mice had significantly less TTS immediately post-exposure than C57BL/6J males or females but not less PTS or hair-cell losses at 20 days post-exposure. (cdc.gov)
  • In a 12 -month carcinogenicity screening assay, C57BL/6 mice (50/sex/group) were exposed to urea in the diet at concentrations of 4500, 9000 or 45000 ppm for 12 months. (europa.eu)
  • Study design The two-bottle choice drinking assay was used to characterise aversion and preference in C57BL/6 mice to a range of menthol concentrations (10-200 µg/mL). (bmj.com)
  • The goal of this study was to examine the effect of the HFD nature on adipose tissue activity, metabolic disturbances and glucose homeostasis alterations in male mice compared with female mice. (biomedcentral.com)
  • To investigate the endometrial transcriptome profile and the associated molecular pathway alterations, we established an ovariectomized C57BL/6 mouse model treated with subcutaneous implantation of 17-β estradiol (E2) pellet and/or high-fat diet (HFD) for 12 weeks to mimic sustained estrogen stimulation and insulin resistance. (scienceopen.com)
  • C57BL/6 wild-type (WT) mice and SIRT3 knockout (KO) mice were randomized into control (Con) or HFD group with or without AIT training for 6 weeks. (hindawi.com)
  • Accordingly, targeted knocking down of either Nav1.7-1.9 or Jak2/Stat3 in DRG neurons in vivo alleviated the hyperalgesia in male Sprague-Dawley rats. (iasp-pain.org)
  • Diet-induced obesity in C57BL/6 mice triggers common features of human metabolic syndrome (MetS). (scienceopen.com)
  • So, the purpose of this study is to identify the relationship between the physical activity level and the hepatic steatosis presence, metabolic syndrome and the risk of developing type 2 diabetes mellitus in men. (scirp.org)
  • Peroxisome Proliferator-Activated Receptors gamma-2 (PPARγ2) and estrogen receptor alpha (ERα) mRNA expression levels in adipose tissue were decreased up to 70% in HFD-fed mice but were more markedly reduced in male mice as compared with female mice. (biomedcentral.com)
  • CONCLUSIONS Our findings indicate that the C57BL/6J has a presumably higher locomotor activity and/or explorative behavior than the hybrid, while the hybrid appeared more sensitive to stress. (stami.no)
  • Therefore, the aim of this study was to investigate the therapeutic effect of the Lebanese Cannabis Oil Extract (COE) in the context of depression and anxiety-like behaviors in C57BL/6J male mice using the Chronic Social Defeat Stress protocol (CSDS). (edu.lb)
  • C57BL/6J mice were fed either a chow diet or HFD including vegetal (VD) or animal (AD) fat. (biomedcentral.com)
  • Sheehan S, Tsaih SW, King BL, Stanton C, Churchill GA, Paigen B, DiPetrillo K. Genetic analysis of albuminuria in a cross between C57BL/6J and DBA/2J mice. (jax.org)
  • This cross is designed to identify the genetic loci that control albuminuria in an intercross: C57BL/6J x DBA/2J (BxD). (jax.org)
  • RESULTS We found that the young males of the C57BL/6J strain spent more time moving in the OF. (stami.no)
  • The cross size is 340 male F2 animals. (jax.org)
  • Compared with males, female mice demonstrate higher capacity in controlling glucose homeostasis in response to 20 weeks HFD feeding. (biomedcentral.com)
  • The hybrid left more fecal pellets than C57BL/6J both in OF and BM. (stami.no)
  • MI was induced in male C57Bl/6 mice by ligation of the left anterior descending coronary artery. (lu.se)
  • results, Royal Jelly is sa fe and effective in the treatment of male infertility. (researchgate.net)
  • There is usually a high female-to-male ratio in mature infections but this inhibits transmission at low densities due to lack of any male partner at the beginning of a new infection. (wikipedia.org)
  • We also demonstrated that human islet engraftment is improved in C57Bl/6-RAG(-/-) mice treated with liraglutide 200 microg/kg sc twice daily (P ≤ 0.05), suggesting that liraglutide should be continued after transplantation. (unige.ch)
  • We evaluated retrospectively medical records of 1399 men (40.7 ± 8.18 years old) who participated in the protocol of Preventive Health Check-up at Hospital Israelita Albert Einstein from January to October 2011. (scirp.org)
  • As of July 1, 2023, limited numbers of male BALB/c mice are available for distribution. (nih.gov)
  • While it seems to persist for years in the thicket rat, P. chabaudi (AS) lasts up to three months in BALB/c or C57Bl/6 mice P. falciparum has been observed to persist for up to a year, and even in conditions of drought when there are no new infections. (wikipedia.org)
  • Next, we generated C57BL/6-Akita Glp1r knockout mice. (medscape.com)
  • Increased glomerular superoxide, upregulated renal NAD(P)H oxidase, and reduced renal cAMP and protein kinase A (PKA) activity were noted in the Glp1r knockout C57BL/6-Akita mice. (medscape.com)
  • C57BL/6 wild-type (WT) mice and SIRT3 knockout (KO) mice were randomized into control (Con) or HFD group with or without AIT training for 6 weeks. (hindawi.com)
  • We produce knockout (KO) mice, conditional knockout (CKO) mice, knock-in (KI) mice, and other types of gene targeting in C57BL/6 ESCs. (nyu.edu)
  • Our lab produces traditional transgenic mice by injecting plasmid or bacterial artificial chromosome DNA constructs into a variety of inbred and outbred mouse strains, including C57BL/6. (nyu.edu)
  • MAIN METHODS: Adult male C57BL/6J mice received a subchronic exposure to corticosterone (CORT) at levels mimicking high physiological stress followed by exposure to the sarin surrogate, diisopropyl fluorophosphate (DFP). (cdc.gov)
  • Methods: Unexposed female and male C57BL/6J mice were mated. (bvsalud.org)
  • Mice (C57BL/6) were given 6 doses of 2.3 mg/kg cisplatin intraperitoneally (IP) on alternating days to induce tactile allodynia as quantified using an electric von Frey (eVF). (karger.com)
  • Coexposure of halothane-treated male mice to lipopolysaccharide to induce modest inflammatory stress converted their mild hepatotoxic response to a pronounced, female-like response. (nih.gov)
  • Laser photocoagulation was performed to induce CNV in C57BL/6J mice, followed by intravitreal injection of SRPIN340 or vehicle. (molvis.org)
  • Controlled cortical impact was used to induce moderate TBI in young and old male C57BL/6 mice. (springer.com)
  • These mice exhibited higher urinary albumin levels and more advanced mesangial expansion than wild-type C57BL/6-Akita mice, despite comparable levels of hyperglycemia. (medscape.com)
  • Because the T-lymphocyte dependency of such a model is controversial, we further assessed the role of T-lymphocytes by determining the occurrence and magnitude of hyperglycemia as well as the pancreatic insulin contents in both STZ-injected nude C57BL/6J male mice and STZ-injected euthymic C57BL/6J male mice selectively depleted in helper and/or cytotoxic T-lymphocytes with monoclonal antibodies (MoAbs). (diabetesjournals.org)
  • Similarly, STZ-injected C57BL/6J male nude mice developed hyperglycemia that was associated with a marked decrease in pancreatic insulin contents on a time course comparable with that of STZ-injected euthymic C57BL/6J male mice depleted in helper or in helper and cytotoxic T-lymphocytes by MoAbs. (diabetesjournals.org)
  • Inbred C57BL/6J mice carry two copies of an age-related hearing loss gene (Ahl). (cdc.gov)
  • C57BL/6J mice were fed with high-fat diet (HFD, 60% fat) for four weeks, and then different doses of SKO-001 ( n = 10 each group) were orally given for 12 weeks. (springer.com)
  • To investigate sex-dependent effects of fibroblast growth factor-21 (FGF21), diet-induced obese male and female wildtype mice were administered two acute doses of FGF21 or saline vehicle. (sdsc.edu)
  • To further determine whether genistein (GEN) modulation of the immune responses was related to its endocrine-disrupting properties and time of exposure, pregnant C57BL/6 mice were exposed to GEN at 0-1250 ppm in feed starting on day 14 of gestation. (nih.gov)
  • Results: PM2.5 exposure during gestation increased body weight (BW) at birth and from weaning to young in male adulthood. (bvsalud.org)
  • We investigated the metabolic effects of anthocyanin-rich black elderberry extract (BEE) in a diet-induced obese C57BL/6J mouse model. (cambridge.org)
  • Male and female C57BL/6J mice were placed on 60% high-fat diet (Research Diets, Cat# D12492) for approx. (sdsc.edu)
  • Here we show in a mouse model that, in males, expansions are already present in primary spermatocytes with no additional expansions occurring in later stages of gametogenesis. (frontiersin.org)
  • To better understand when expansion occurs during paternal transmission in the FX PM mouse model, we monitored the repeat size in sperm and in different populations of immature male gametes. (frontiersin.org)
  • Males from FA/PM2.5 group were protected from these phenotypes showing higher O2 consumption and Ucp1 in the brown adipose tissue. (bvsalud.org)
  • The aim of this study was to assess the effects of specific regimens of enrichment on the behaviour of C57BL/6J mice in the elevated plus-maze test (EPM). (awionline.org)
  • The items of CF that were used in this study appeared to improve the quality of life of C57BL/6J mice, as assessed using the EPM. (awionline.org)
  • The present study investigated whether PU could protect against GM‑induced ototoxicity in C57BL/6J mice and House Ear Institute‑Organ of Corti 1 (HEI‑OC1) cells. (spandidos-publications.com)
  • C57BL/6J mice and HEI‑OC1 cells were used to establish models of GM‑induced ototoxicity in this study. (spandidos-publications.com)
  • Male DBA/2d-mice and C57BL/6b-mice were used in the study. (cdc.gov)
  • Eight-week-old C57BL/6J male mice (CLEA Japan, Tokyo, Japan) were used for this study. (molvis.org)
  • One study with C57BL/6 mice demonstrated that the interaction of L. major-infected macrophages with dying neutrophils induced parasite destruction mediated by neutrophil elastase and tumour necrosis factor-α production from neutrophils [5]. (who.int)
  • A total of 192 male C57BL/6J mice were allocated randomly to 32 cages. (awionline.org)
  • CeA-Tac2 antagonism and its pharmacogenetic temporal inhibition impair fear memory in male mice. (nature.com)
  • 2010. The effect of three different items of cage furniture on the behaviour of male C57BL/6J mice in the plus-maze test. (awionline.org)
  • Next, we studied two Ins2 Akita diabetic mouse models showing different susceptibility to the development and progression of DN, DN-resistant C57BL/6- Ins2 Akita (C57BL/6-Akita), and DN-prone KK/Ta- Ins2 Akita (KK/Ta-Akita). (medscape.com)
  • This effect on DAT prompted us to investigate whether the serotonin transporter (SERT) exhibits similar alterations upon RGS12 loss in C57BL/6J mice. (duke.edu)
  • We have shown that RGS12 loss diminishes locomotor responses of C57BL/6J mice to dopamine transporter (DAT)-targeting psychostimulants. (duke.edu)
  • In F(1) males, GEN increased the terminal body and spleen weights (25 and 250 ppm), the number of CD4(+)CD8(+) and CD4(-)CD8(+) thymocytes (25 ppm), and the number of splenic T cell subsets and NK cells (25 and 250 ppm). (nih.gov)
  • Mutations can be created by direct injection into C57BL/6 fertilized mouse oocytes as well as into embryonic stem cells (ESCs) in culture. (nyu.edu)