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  • severe
  • In large trials, parenteral artesunate (an artemisinin derivative) reduced severe malaria mortality by 22·5% in Africa and 34·7% in Asia compared with quinine, whereas adjunctive interventions have been uniformly unsuccessful. (nih.gov)
  • The developers are non-profit In November 2012 a Phase III trial of RTS,S found that it provided modest protection against both clinical and severe malaria in young infants. (wikipedia.org)
  • Missing the booster dose reduced the efficacy against severe malaria to a negligible effect. (wikipedia.org)
  • Three doses of vaccine plus a booster reduced the risk of clinical episodes by 26 percent over three years, but offered no significant protection against severe malaria. (wikipedia.org)
  • diagnostic tests
  • Malaria antigen detection tests are a group of commercially available rapid diagnostic tests of the rapid antigen test type that allow quick diagnosis of malaria by people who are not otherwise skilled in traditional laboratory techniques for diagnosing malaria or in situations where such equipment is not available. (wikipedia.org)
  • Antigen-based rapid diagnostic tests (RDTs) have an important role at the periphery of health services capability because none of the rural clinics has the ability to diagnose malaria on-site due to a lack of microscopes and trained technicians to evaluate blood films. (wikipedia.org)
  • The Imagine No Malaria campaign has the goal of getting medicines and diagnostic tests to those hospitals and clinics. (wikipedia.org)
  • placental malaria
  • In 1998, a review of clinical studies concluded that the numerous studies published to that date had failed to show any convincing and consistent link between HIV and malaria, with the exception of an increased rate of placental malaria in HIV-infected pregnant women. (ucsf.edu)
  • Placental HIV-1 viral load is increased in women with placental malaria, especially those with high parasite densities. (ucsf.edu)
  • Pregnancy-associated malaria (PAM) or placental malaria is a presentation of the common illness that is particularly life-threatening to both mother and developing fetus. (wikipedia.org)
  • types of malaria
  • Since 4 November 2010, using the financial support from Bill & Melinda Gates Foundation, Malariacontrol.net developed an open-source software named "Open Malaria" which can be used to simulate outcomes in various types of malaria transmission settings. (wikipedia.org)
  • effect of malaria
  • 13 ) However, the effect of malaria on mother-to-child transmission of HIV is unclear because published studies to date have given conflicting findings. (ucsf.edu)
  • However, the effect of malaria interventions across the varied epidemiological settings of Africa remains poorly understood owing to the absence of reliable surveillance data and the simplistic approaches underlying current disease estimates. (wikipedia.org)
  • In September 2015, research by MAP published in Nature quantified the attributable effect of malaria disease control efforts in Africa. (wikipedia.org)
  • episodes of malaria
  • This study suggests that malaria may speed the progression of HIV disease, and this is supported by a study from Uganda showing increased CD4 cell decline associated with episodes of malaria despite prompt treatment. (ucsf.edu)
  • Detection and specific identification of malaria parasite species by microscopy on blood films in a laboratory with appropriate expertise in any person (symptomatic or asymptomatic) diagnosed in the United States, regardless of whether the person experienced previous episodes of malaria while outside the country. (cdc.gov)
  • Detection of unspeciated malaria parasite by microscopy on blood films in a laboratory with appropriate expertise in any person (symptomatic or asymptomatic) diagnosed in the United States, regardless of whether the person experienced previous episodes of malaria while outside the country. (cdc.gov)
  • countries where malaria
  • The vast majority of cases in the United States are in travelers and immigrants returning from countries where malaria transmission occurs, many from sub-Saharan Africa and South Asia. (cdc.gov)
  • The plan also calls to implement malaria elimination activities in areas where elimination seems possible, reverse trends in countries where malaria case were on the rise, and prevent any reintroduction of malaria in countries deemed malaria-free. (wikipedia.org)
  • international malaria
  • Imagine No Malaria also includes an advocacy effort that calls for support by urging elected officials in Congress to protect global health funds (which includes international malaria aid) in the US budget. (wikipedia.org)
  • antimalarial drugs
  • The project also recommended that screening the whole human population for malaria before treating them would be more cost effective when compared to indiscriminate treatment of the whole population with antimalarial drugs. (wikipedia.org)
  • The work of MAP falls into three areas: The estimation of the spatial distribution of malaria prevalence and incidence and related topics such as the spatial distribution of insecticide treated nets, antimalarial drugs, mosquito vectors, and human blood disorders Disseminating data on malaria via the Repository for Open Access Data (ROAD-MAP) project Providing maps relating to malaria prevalence and related topics for the World Health Organization (WHO) and other bodies. (wikipedia.org)
  • The study aimed to understand the effect of various antimalarial drugs on relapses of malaria, primarily from the 8-aminoquinoline group of compounds. (wikipedia.org)
  • elimination
  • engage communities in malaria elimination using innovative communication tools. (who.int)
  • Countries requested support from WHO to achieve their malaria elimination goals. (who.int)
  • Accelerating malaria elimination in the Greater Mekong will not only improve lives today. (who.int)
  • Enthusiasm for malaria elimination has resurfaced. (nih.gov)
  • malarial
  • On the other hand, the control of malaria parasitemia is immune mediated, and this prevents most malarial infections from becoming clinically apparent in semi-immune adults in endemic areas. (ucsf.edu)
  • WHO-recommended malaria control tools include: long-lasting insecticidal bed-nets, spraying inside walls of dwellings with insecticides, preventive treatment for infants and during pregnancy, prompt diagnostic testing, and treatment of confirmed cases with effective anti-malarial medicines. (who.int)
  • The leading journal on malarial research, Malaria Journal serves the community interested in malaria in its broadest sense. (springer.com)
  • In 2012, Malaria Control has studied the effectiveness of using RTS,S malaria vaccine in World Health Organization's Expanded Programme on Immunization (EPI) in different malarial transmission settings and reported that such programme only has modest benefits over 14 years period. (wikipedia.org)
  • occurs
  • Malaria generally occurs in areas where environmental conditions allow parasite multiplication in the vector. (cdc.gov)
  • Malaria occurs in tropical and subtropical climate s, mostly Africa , South America , the Middle East , India and all of Southeast Asia . (everything2.com)
  • clinical
  • 9 ) The increases in viral load were greatest in those with clinical malaria, high levels of parasitemia, and relatively high CD4 counts. (ucsf.edu)
  • Clear evidence indicates an interaction between HIV-1 and malaria in pregnancy, causing more peripheral and placental parasitemia, higher parasite densities, more clinical malaria, more anemia, and increased risks of adverse birth outcomes. (ucsf.edu)
  • epidemiology
  • Studies in men and nonpregnant women show that the underlying epidemiology and intensity of malaria transmission seem to be critical for determining the consequences of coinfection. (ucsf.edu)