• With a background in Molecular Biology, he is passionate about transforming biomedical experimentation. (mseq.vc)
  • This subclass comprises research and experimental development in plant cell and molecular biology. (ubc.ca)
  • In your first year, your modules give you an insight into various biological and chemical disciplines, including biochemistry, cell and molecular biology, microbiology and physiology. (kent.ac.uk)
  • For a researcher armed with the powerful tools of genetics and molecular biology, the simple bacterial cells provide great experimental systems for investigating fundamental functions of a living cell. (lu.se)
  • This course element will introduce you to the fundamental principles of medically related cell biology and molecular and clinical genetics. (le.ac.uk)
  • The essential biochemistry, genetics, cell biology, and metabolic pathways underlying the survival and success of all living organisms. (queensu.ca)
  • The BS program in biological sciences with a concentration in genetics, cell and developmental biology integrates the study of three exciting, closely related areas of life science research. (asu.edu)
  • Genetics examines the blueprints of life, such as DNA sequence and gene expression, while cell biology studies the machinery of life enclosed within the boundaries of cells. (asu.edu)
  • Developmental biology uses both genetics and cell biology to understand how genes and the environment interact to produce a whole new individual from a single cell as well as to understand the various developmental changes that organisms undergo throughout life. (asu.edu)
  • The combined study of genetics, cell biology and development has resulted in a better understanding of many diseases and promises to prove even more important in the future. (asu.edu)
  • If you are an outstanding cell, molecular or structural biologist and would like to establish an independent research group in either the Institute of Cell Biology or the Institute of Quantitative Biology, Biochemistry and Biotechnology at the University of Edinburgh, then we should be pleased to consider sponsoring you for a fellowship to make this possible. (ed.ac.uk)
  • Our Biochemistry degree is recognised by the Royal Society of Biology (RSB). (kent.ac.uk)
  • When the oxygen content of body tissues is low or the number of red blood cells decreases, the kidneys produce and release erythropoietin , a hormone that stimulates the bone marrow to produce more red blood cells. (msdmanuals.com)
  • Cell Biol. (nature.com)
  • Trends Cell Biol. (nature.com)
  • Prospective students must take three upper division courses (BIOL 3100, BIOL 3120 and BIOL 5130 (Animal Tissue Culture Techniques) so that they gain thorough understanding of the principles of molecular and cellular biology, have familiarity with molecular manipulation techniques, and extensive experience with basic cell culture techniques. (csusb.edu)
  • Nat Rev Mol Cell Biol , Art. (mpi-cbg.de)
  • This domain may be implicated in the binding of extracellular molecules and other nearby cells. (wikipedia.org)
  • In cells, some molecules can move down their concentration gradients by crossing the lipid portion of the membrane directly, while others must pass through membrane proteins in a process called facilitated diffusion. (khanacademy.org)
  • Logically, the team is interested in finding out whether and by what means the dendritic cell redirects the transport of MHC molecules depending on the nature of microbial products that it has detected. (univ-mrs.fr)
  • By looking under the microscope at the behavior of MHC molecules in dendritic cells we found that the addition of microbial products induces dramatic changes in all cells in our culture," says Evelina Gatti, co-leader on this team subject. (univ-mrs.fr)
  • Initially on the inside of the cells, MHC molecules were suddenly exposed on the outside of the cell. (univ-mrs.fr)
  • We tried to understand how the dendritic cell organized trafficking of MHC molecules. (univ-mrs.fr)
  • Dendritic cell activation (MHC II molecules in green, Lysosomes in red, nuclei in grey). (univ-mrs.fr)
  • This allows the molecules to have a "ticket" for restricted access into specialized compartments of the cell. (univ-mrs.fr)
  • Change in the distribution of MHC class II molecules within a dendritic cell in the presence (top) or absence (bottom) of the ubiquitin ligase MARCH1. (univ-mrs.fr)
  • The wider question that we want to understand is how molecules of a cell govern such essential and complex functions like cell division, cell polarity, determination of cell shape, and cell differentiation. (lu.se)
  • Processes like these have evolved from common ancestors of both eukaryotes and prokaryotes, and it becomes increasingly clear that the bacterial versions of these basic cell functions use similar ancestral molecules, for example cytoskeletal proteins, as those used in animal and plant cells. (lu.se)
  • The knowledge about essential cell functions in bacteria and the experimental systems that we develop can be used to find new targets for antibiotics and to screen for molecules that can work as antibiotics. (lu.se)
  • To study processes at the level of single molecules and single cells, the tools need to be on the same size scale as the objects under study. (lu.se)
  • Mechanochemical Principles of Spatial and Temporal Patterns in Cells and Tissues. (mpi-cbg.de)
  • Patterns are ubiquitous in living systems and underlie the dynamic organization of cells, tissues, and embryos. (mpi-cbg.de)
  • Anatomy (4 hours): Main structures and features of the human body (systems, organs, tissues). (kth.se)
  • Several ECNMs are known to induce irreversible damage to exposed tissue (e.g., fibrosis) in animal models or cause genetic damage (i.e., genotoxicity) upon exposure to sensitive tissues/cells, a key first step at initiating tumorigenesis. (cdc.gov)
  • C. Peterson, M. Ringne´r / Artificial Intelligence in Medicine 28 (2003) 59-74 structure and function, cellular metabolism, development of cells and tissues, and response of organisms to their environments. (lu.se)
  • Since genes are composed of a given alphabet (A, T, C, G) with fixed pairing properties A-T and C-G, probes can be constructed that attract gene transcripts extracted from cell tissues and cultures. (lu.se)
  • We developed a mouse model that recapitulates the FL hallmark t(14;18) translocation, which results in constitutive activation of antiapoptotic protein B cell lymphoma 2 (BCL2) in a subset of B cells, and applied a combination of molecular and immunofluorescence approaches to track normal and t(14;18)(+) memory B cells in human and BCL2-overexpressing B cells in murine lymphoid tissues. (bvsalud.org)
  • Lymphocytes One of the body's lines of defense ( immune system) involves white blood cells (leukocytes) that travel through the bloodstream and into tissues, searching for and attacking microorganisms and. (msdmanuals.com)
  • Given this background, it is the goal of the Department of Cell Biology to foster a supportive and inclusive work environment in which the guiding principles of scientific integrity, innovation, open communication, training, career advancement and discovery research can flourish. (duke.edu)
  • Mr Victor Maqueda gave an introductory presentation on the main principles of WHO GMP. (who.int)
  • Our lab is multidisciplinary in nature and provides an interesting environment for scientists with experience in tumor biology, molecular cell biology, and/or translational cancer research. (lu.se)
  • During the M phase, the duplicated chromosomes are separated and distributed to two genetically identical daughter cells. (jove.com)
  • Chromosomes are made of a material called chromatin, which is dispersed throughout the cell nucleus during interphase. (visionlearning.com)
  • In Cell Division I: The Cell Cycle , we learned that Flemming observed how chromosomes became visible in patterns that repeated each time the cells of fire salamanders divided. (visionlearning.com)
  • In some large eggs, when a small spindle lies parallel to the membrane at one side of the cell the resultant cleavage furrow forms at that side over the former metaphase plate, and as it contracts, the furrow propagates around the equator of the cell. (upstate.edu)
  • Cleavage of the SARS-CoV-2 S2 spike protein required for viral entry into cells can be accomplished by proteases TMPRSS2 located on the cell membrane, or by cathepsins (primarily cathepsin L) in endolysosomes. (wikipedia.org)
  • In many ways, airport security is a lot like the plasma membrane of a cell. (khanacademy.org)
  • Passive transport does not require the cell to expend any energy and involves a substance diffusing down its concentration gradient across a membrane. (khanacademy.org)
  • But this recharging process relies on a complex sequence of reactions involving various protein complexes embedded in the cell membrane. (singularityhub.com)
  • Re-engineering this system to work outside of a cell is challenging because it requires the various proteins to be carefully orientated in an artificial membrane, which makes it both finicky and fragile. (singularityhub.com)
  • The TMPRSS2 protein is found in high concentration in the cell membranes of epithelial cells of the lung and of the prostate, but also in the heart, liver and gastrointestinal tract. (wikipedia.org)
  • Cell membranes are selectively permeable , regulating which substances can pass through, as well as how much of each substance can enter or exit at a given time. (khanacademy.org)
  • In the blood, mucous membranes and lymphoid organs, dendritic cells provide a dual role as sentinels, but also as conductors of the immune orchestra. (univ-mrs.fr)
  • To recharge it, the cell needs to use energy from food or photosynthesis to add a phosphate group back onto the ADP molecule, turning it back into ATP. (singularityhub.com)
  • No prerequisites, except high-school biology, is required. (kth.se)
  • However, now as in the past, mitochondria divide independently of the cell and possess some genes of their own. (goethe-university-frankfurt.de)
  • As the sequencing and gene annotation projects of entire genomes of many species are headed towards completion (see, e.g. [13] ), massive mapping efforts in biology are now focused on how the genes interact. (lu.se)
  • The molecular interactions of genes and gene products underlie fundamental questions of biology. (lu.se)
  • For gene therapy, a combinatorial approach with multiple target genes, as well as more complex optogenetic approaches are studied, while for cell-therapy human induced pluripotent stem cells and human induced neuronal cells are investigated. (lu.se)
  • When doing studies with human samples, including iPS (induced pluripotent stem) cells or embryonic stem cells, be particularly careful about possible restrictions on their use and terms of IRB (Institutional Review Board) approvals. (duke.edu)
  • NSCs are derived from the embryonic stem (ES) cells or fetal and adult nervous system, and can generate different type of neural cells. (lu.se)
  • was regarded solely in charge of the exceptionally solid binding affinity of Clone 13 (L at GP1 260) to its cellular receptor α-dystroglycan which among cells from the immune system is normally preferentially portrayed on dendritic cells and therefore alters dendritic cell function resulting in viral persistence. (biospraysehatalami.com)
  • Recommended 4U Biology and Chemistry, or equivalent high school background. (queensu.ca)
  • The IFCB is also represented in the International Cell Research Organization (ICRO) which functions in UNESCO. (lviv.ua)
  • This course introduces molecular, structural and functional organization in both prokaryotic and eucaryotic cells. (laurentian.ca)
  • We are also applying advanced microscopy, which in recent years has revolutionized the understanding of prokaryotic cells and visualized the remarkable degree of three-dimensional organization, complexity, and beauty of these deceivingly simple organisms. (lu.se)
  • The newly funded 2022-2026 California Institute for Regenerative Medicine (CIRM) Bridges to Stem Cell Research Internship Program (CIRM Bridges) is a state government funded program aimed to broaden the participation in stem cell research by individuals representing the diversity of California's population. (csusb.edu)
  • The previously funded (2010-2022) internship program has allowed the CSUSB Biology Department to develop a quality stem cell education and training program that has resulted in 120+ students getting training in stem cell labs in Southern California. (csusb.edu)
  • What makes it difficult to unravel such signaling processes," explains Münch, himself a biochemist, "is that an incredibly large number take place simultaneously and at high speed in the cell. (goethe-university-frankfurt.de)
  • Our aims are to identify and understand mechanisms regulating breast cancer cell death and how inflammatory signaling can be induced and influence breast cancer progression. (lu.se)
  • We have discovered that Smac mimetics can induce long-term changes in the breast cancer cell phenotype which includes inflammatory signaling. (lu.se)
  • This gene is up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. (wikipedia.org)
  • Your second year builds on this knowledge and covers areas such as gene regulation, cell biology and metabolism. (kent.ac.uk)
  • The main emphasis is on supervised machine learning methods for classification and prediction of tumor gene expression profiles. (lu.se)
  • Main emphasis of Epilepsy Center is to explore mechanisms underlying epileptogenesis, and develop gene- and cell-therapy based treatment strategies for epilepsy. (lu.se)
  • Coordination of this cellular machinery results in the eventual formation of two separate and fully functioning daughter cells. (upstate.edu)
  • If a cell needs to spend that energy, it breaks off one of the molecule's three phosphate groups and the energy bound up in that chemical bond can then power some cellular process. (singularityhub.com)
  • These are processed together in the cell and trigger a support mechanism to restore cellular balance (homeostasis). (goethe-university-frankfurt.de)
  • Using single cell RNA sequencing, we aim to identify which cellular processes are affected by type 2 diabetes and in which islet and small intestinal cell type this occurs. (lu.se)
  • PhD in Molecular and cellular biology, University of Poitiers, France. (lu.se)
  • The faculty have a common research interest in cancer, focusing on a variety of topics, including signal transduction, epigenetic regulation, tumor microenvironment and metastasis, dormancy and reactivation, DNA damage and repair, translational regulation, stem cell and reprogramming, drug resistance and drug discovery. (utoledo.edu)
  • Creating human cell constructs for research is a manual, difficult and time consuming process - a single experiment can take up to 9 days to prepare. (mseq.vc)
  • I have been teaching a variety of courses here at Queen's for over 20 years, from introductory biology to the commercialization of biological research at the graduate level. (queensu.ca)
  • My main research focus is on protein transport mechanisms and rhomboid proteins. (queensu.ca)
  • and 2) to give our large, ethnically diverse student population a basic understanding of stem cell research through our curriculum offerings. (csusb.edu)
  • Six undergraduate and 4 graduate students per year will be selected to participate in the stem cell research internships during the 5-year duration of this grant. (csusb.edu)
  • All interns will also participate in a 1-week Stem Cell Techniques Training course at the UCR CIRM Shared Research Laboratory prior to starting their internships. (csusb.edu)
  • The interns will be assigned both a research mentor from the institution in which they will be doing their stem cell research and a CSU faculty mentor to guide them during their internships. (csusb.edu)
  • reflect on current scientific challenges within stem cell research and how this research influences society in general · reflect on ethical issues relating to sustainable stem cell research and regenerative medicine. (lu.se)
  • The purpose of our research is to understand how each islet cell type and each enteroendocrine cell type in the gut is affected in type 2 diabetes. (lu.se)
  • Researchers from Lund have developed a completely animal-free preparation for cell culture, a medium that can be used to grow human cells, including for cancer research. (lu.se)
  • This has sparked a lot of interest in many parts of Europe and also with the US Food and Drug Administration (US FDA), not least because it can be used to grow normal cells but also in cancer research. (lu.se)
  • Visit the Tumor Cell Biology groups research portal via this link. (lu.se)
  • The Research School in Stem Cell Biology is a collaborative academic program that emphasizes high-quality research training and professional growth, offering a wide range of engaging educational activities to empower aspiring stem cell scientists and lay a solid foundation for their future success. (lu.se)
  • PhD in Biology from University of Duisburg-Essen and German Cancer Research Center (DKFZ), Germany. (lu.se)
  • It gives me a lot of energy when your work uncovers brand-new unknown information in cancer research by focusing on the smallest details in cells. (lu.se)
  • In particular, we encourage people with experience in both basic cell biology research and more patient oriented research (or with a strong motivation to learn the other discipline) to apply. (lu.se)
  • Among the main objectives of our group in particular is to encourage interdisciplinary and collaborative research involving biologists and research oriented physicians in order to develop and apply new strategies for the diagnosis and treatment of cancer patients. (lu.se)
  • One of our main research areas is to develop methods to identify microorganisms. (lu.se)
  • Research groups are gathered within five main research clusters: MultiPark, Stem Cell Center and Epilepsy Center. (lu.se)
  • Lund center for Stem Cell Biology and Cell Therapy is one of six Swedish strategic centers of excellence in life sciences, supported by the Swedish Foundation for Strategic Research. (lu.se)
  • The possibility to isolate and propagate NSCs and their potential applications in cell therapy have attracted a lot of research interest in recent years. (lu.se)
  • A differ from a lysine (K) to a glutamine (Q) at placement 1079 in the L proteins an RNA-dependent RNA polymerase selectively elevated viral titers in macrophages however not in various other cell types examined (14). (biospraysehatalami.com)
  • The consequences for both the mitochondrion and the cell are dramatic: Misfolded proteins can, for example, disrupt energy production or lead to the formation of larger amounts of reactive oxygen compounds, which attack the mitochondrial DNA and generate further misfolded proteins. (goethe-university-frankfurt.de)
  • Normally, DNAJA1 supports a specific chaperone (folding assistant) in the cell, which molds the cell's newly formed proteins into the correct shape. (goethe-university-frankfurt.de)
  • But in 2018, researchers in Lund started using different human proteins needed for cell survival in a cell culture medium. (lu.se)
  • So far, it has been known that IL-22 is mainly produced by lymphoid lineage cells. (researchgate.net)
  • This is the moment when the cells detect the microbes or danger, change their biological functions and begin their migration to secondary lymphoid organs. (univ-mrs.fr)
  • The researchers from Goethe University Frankfurt artificially triggered misfolding stress in the mitochondria of cultured human cells and analyzed the result. (goethe-university-frankfurt.de)
  • The result is that the mitochondria send two chemical signals to the cell when protein misfolding stress occurs: They release reactive oxygen compounds and block the import of protein precursors, which are produced in the cell and are only folded into their functional shape inside the mitochondrion, causing these precursors to accumulate in the cell. (goethe-university-frankfurt.de)
  • Several viruses, including SARS-CoV-2, use the protease activity of the TMPRSS2 protein in the process of entering cells. (wikipedia.org)
  • The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. (wikipedia.org)
  • Scientists also added various protein extracts from animals to make the cells grow. (lu.se)
  • These subsets arose from different progenitors and were both class switched, somatically mutated, and intrinsically biased in their differentiation fate toward plasma cells. (bvsalud.org)
  • Thus, these organisms are of a huge industrial and medical importance, and an improved understanding of their biology, growth habits, regulatory mechanisms, and cell differentiation will greatly facilitate the exploration of streptomycetes in various industrial and biotechnological applications. (lu.se)
  • It was formally established in St. Louis in 1972 to coordinate and support Cell Biology activities throughout the world, as well as representing cell biology in the International Union of Biological Sciences. (lviv.ua)
  • PhD in Biology and Biological Engineering from Chalmers University of Technology, Sweden. (lu.se)
  • He added that it could be a key enabler to make "electrobiosynthesis" possible, the idea of using electricity to directly power the synthesis of useful chemicals by cells. (singularityhub.com)
  • The model organisms that we use, Gram-positive bacteria of the genus Streptomyces , provide unique possibilities to study some of these fundamental functions, and show several intriguing parallels to the corresponding processes in eukaryotic cells. (lu.se)
  • As members of the Department of Cell Biology we are all greatly privileged to be able to pursue our dreams of discovering new knowledge, widening horizons, and improving the well-being of future generations, both in our own communities and throughout the world. (duke.edu)
  • Researchers at Goethe University Frankfurt have investigated to what extent their metabolism has blended with that of their host cells in the course of evolution, using the example of a mitochondrial stress response. (goethe-university-frankfurt.de)
  • How closely the cell and the mitochondrion work together in human cells today is what a team of researchers led by Dr. Christian Münch of Goethe University Frankfurt is investigating. (goethe-university-frankfurt.de)
  • He received his A.B. in biology and his M.D. from Boston University. (cdc.gov)
  • Dr. Baratz received his Ph.D. in cell biology and anatomy and his D.D.S. from Northwestern University. (cdc.gov)
  • Dr. Greenberg received his B.A. and M.A. in biology from Hofstra University, his M.D. from Temple University School of Medicine, and his M.P.H. in occupational medicine from the Medical College of Wisconsin. (cdc.gov)
  • When using cell lines or mouse strains, have accurate records of their origin and genetic background, and how they are identified and maintained. (duke.edu)
  • But what all these life forms have in common is that their genetic code is copied from cell to cell thanks to the process of mitosis, whereby the nucleus of a cell splits into two before the cell divides. (visionlearning.com)
  • It lost a large part of its genetic material - its DNA - and exchanged smaller DNA segments with the mother cell. (goethe-university-frankfurt.de)
  • Triggers for such stress can be infections, inflammatory diseases or genetic disorders, for example, but also nutrient deficiencies or cell toxins. (goethe-university-frankfurt.de)
  • T-cell acute lymphoblastic leukaemias (T-ALL) are aggressive malignant proliferations characterized by high relapse rates and great genetic heterogeneity. (bvsalud.org)
  • To avert this potential crisis, the cell devotes a substantial amount of energy during early mitosis to gradually reorganizing the sister chromatids into shorter structures that separate more easily. (jove.com)
  • The term mitosis refers specifically to the process whereby the nucleus of a eukaryotic cell splits into two identical daughter nuclei prior to cell division. (visionlearning.com)
  • The rate at which mitosis occurs depends on the cell type. (visionlearning.com)
  • This radiolabeled monoclonal antibody from Telix Pharmaceuticals targets carbonic anhydrase IX (CAIX), an enzyme that regulates cell proliferation and is highly expressed in many tumor types. (medscape.com)
  • We have thesis projects for Masters students in tumor biology. (lu.se)
  • Thus, diverse transcriptional programs in MBCs are not linked to specific effector fates but rather to divergent strategies of the immune system to simultaneously provide rapid protection from reinfection while diversifying the initial B cell repertoire. (bvsalud.org)
  • Their main machine, RASTRUM, can create cell models that closely and predictably imitate real human tissue structure and behaviour across a range of disease states, allowing for researchers to bypass the arduous process of creating cell constructs. (mseq.vc)
  • In tissue culture cells when the spindle is positioned asymmetrically, actin and myosin assemble over the former metaphase plate in an asymmetric pattern and contraction is asymmetric, beginning at the side of the cell closest to the spindle. (upstate.edu)
  • Hiding in the entryways used by pathogens, dendritic cells locate infectious agents, ingest them and release biochemical signals to alert the first line of defensive cells in the body and draw them to the site of the infection. (univ-mrs.fr)
  • Since these observations, our team has collected an enormous amount of new data on the biochemical pathways involve with the acquisition by dendritic cells of unmatched immunomodulatory functions. (univ-mrs.fr)
  • This course is a study of the fundamental activities of cell organelles and their form and function as exemplified in plant and animal cells as well as the ultra-structure of cells. (voorhees.edu)
  • Please email questions, comments and suggestions to the Cell and Cancer Biology track director, Dr. Xiaohong Li . (utoledo.edu)
  • Member of the mentoring faculty for the Biomedical Sciences Graduate Program (Cell and Cancer Biology Track). (utoledo.edu)
  • You also choose two optional modules from a range that covers areas such as the biology of ageing, cancer biology and neuroscience. (kent.ac.uk)
  • What would happen if the nucleus was missing from the animal cell? (blurtit.com)
  • This killed the cells, just as the earlier dyes had killed the cells of other laboratory animals. (visionlearning.com)
  • In time series experiments, which for many experimental systems are confined to laboratory cell culture experiments (cell lines), each slide corresponds to a measured time point. (lu.se)
  • Comparison of the structural and functional specialisations of cells lining the stomach with those of the cells lining the small intestine. (markedbyteachers.com)
  • Prof. Lindvall and Dr. Kokaia were the first in the world to show that the brain produces new neurons in response to stroke which opened new possibilities for cell therapy by developing the way to modulate and direct brains this self-repair mechanisms. (lu.se)
  • diagnostic prediction of small round blue cell tumors (SRBCT) of childhood and determining the estrogen receptor (ER) status of sporadic breast cancer. (lu.se)
  • Combined analysis of antigen specificity and B cell receptor repertoire segregated these subsets into "bona fide" virus-specific MBCs and "bystander" MBCs with no apparent specificity for eliciting viruses generated through an alternative permissive process. (bvsalud.org)
  • Paradoxically, while we have known for a long time the key role played by these cells in the activation of B and T lymphocytes, and we identified the sensors that allow them to detect danger signals emitted by pathogens, operation of this interface remains partly a mystery. (univ-mrs.fr)
  • To deliver these immunological instructions, antigen (in practice a peptide a few amino acids in length) is not presented in isolation to T lymphocytes by dendritic cells but is nestled in a pocket formed by a molecule, known as the Major Histocompatibility Complex (called HLA in humans). (univ-mrs.fr)
  • Each module contains lectures by experienced stem cell researchers, followed by preparation, analysis and discussion of material in compulsory practical exercises, and concludes with an assessed assignment. (lu.se)
  • It took off in 1958 when researchers discovered that fetal bovine serum (FBS) was an additive that could make cells thrive, both normal and cancerous. (lu.se)