Filter...

AnatomyOrganismsChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsInformation Science

Select a category...

Transcription FactorsMEF2 Transcription FactorsTranscription, GeneticDNA-Binding ProteinsPromoter Regions, GeneticSp1 Transcription FactorGene Expression RegulationMolecular Sequence DataBase SequenceTranscriptional ActivationBinding SitesTrans-ActivatorsBasic Helix-Loop-Helix Transcription FactorsProtein BindingMyogenic Regulatory FactorsNuclear ProteinsRNA, MessengerTranscription Factor AP-1Cell LineGene Expression Regulation, DevelopmentalRepressor ProteinsSignal TransductionHomeodomain ProteinsAmino Acid SequenceForkhead Transcription FactorsDNAMutationCell DifferentiationBasic-Leucine Zipper Transcription FactorsTransfectionCell NucleusTranscription Factor AP-2Cells, CulturedKruppel-Like Transcription FactorsGenes, ReporterTranscription Factors, TFIIChromatin ImmunoprecipitationGATA4 Transcription FactorHeLa CellsYY1 Transcription FactorSTAT3 Transcription FactorNFATC Transcription FactorsTranscription Factor TFIIDActivating Transcription Factor 3Reverse Transcriptase Polymerase Chain ReactionElectrophoretic Mobility Shift AssayNF-kappa BSp3 Transcription FactorEnhancer Elements, GeneticZinc FingersTranscription Initiation SitePaired Box Transcription FactorsActivating Transcription Factor 2Gene Expression ProfilingRecombinant Fusion ProteinsTranscription Factor TFIIBRegulatory Sequences, Nucleic AcidCloning, MolecularE2F1 Transcription FactorRNA Polymerase IIPlasmidsBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsGene ExpressionProtein Structure, TertiaryGATA3 Transcription FactorPhosphorylationGATA1 Transcription FactorGATA2 Transcription FactorTCF Transcription FactorsLuciferasesGene Expression Regulation, FungalGATA Transcription FactorsMice, KnockoutMicrophthalmia-Associated Transcription FactorMADS Domain ProteinsCell Line, TumorModels, BiologicalSTAT1 Transcription FactorActivating Transcription FactorsHelix-Loop-Helix MotifsMice, TransgenicBlotting, WesternSequence Homology, Amino AcidOligonucleotide Array Sequence AnalysisChromatinTranscription Factor RelAE2F Transcription FactorsCyclic AMP Response Element-Binding ProteinSaccharomyces cerevisiaeMice, Inbred C57BLSaccharomyces cerevisiae ProteinsProto-Oncogene ProteinsDrosophila ProteinsGene Expression Regulation, PlantActivating Transcription Factor 4Down-RegulationTranscription Factor 7-Like 1 ProteinGATA6 Transcription FactorActivating Transcription Factor 1Neurons

MyocyteGeneApoptosisHistoneBindsDifferentiationMEF2DRegulatoryGenesMembersDevelopment

Myocyte3

• The transcription factors in the myocyte enhancer factor 2 (MEF2) family play important roles in cell survival by regulating nuclear gene expression. (nih.gov)
• Myocyte-specific enhancer factor 2D is a protein that in humans is encoded by the MEF2D gene. (wikipedia.org)
• This gene is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. (nih.gov)

Gene3

• Fourth, cross-modal analysis provides compelling evidence for the transcriptomic, epigenomic and gene regulatory basis of neuronal phenotypes such as their physiological and anatomical properties, demonstrating the biological validity and genomic underpinning of neuron types. (nih.gov)
• Here, we report that MEF2D is present in rodent neuronal mitochondria, where it can regulate the expression of a gene encoded within mitochondrial DNA (mtDNA). (nih.gov)
• Mbd2 binds regulatory DNA regions of neuronal genes in the hippocampus and loss of Mbd2 alters the expression of hundreds of genes with a robust down-regulation of neuronal gene pathways. (bvsalud.org)

Apoptosis2

• Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. (nih.gov)
• Plays a critical role in the regulation of neuronal apoptosis (By similarity). (nih.gov)

Histone1

• Members of this family are involved in control of muscle and neuronal cell differentiation and development, and are regulated by class II histone deacetylases. (nih.gov)

Binds2

• MEF2C is a transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. (thermofisher.com)
• Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific, growth factor- and stress-induced genes. (nih.gov)

Differentiation1

• Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. (nih.gov)

MEF2D2

• Immunocytochemical, immunoelectron microscopic, and biochemical analyses of rodent neuronal cells showed that a portion of MEF2D was targeted to mitochondria via an N-terminal motif and the chaperone protein mitochondrial heat shock protein 70 (mtHsp70). (nih.gov)
• MEF2D binding induced ND6 transcription. (nih.gov)

Regulatory1

• Further, a genome-wide DNA methylation analysis found an altered DNA methylation pattern in regulatory DNA regions of neuronal genes in Mbd2-/- mice. (bvsalud.org)

Genes2

• Many such complexes act mechanistically by altering epigenetic profiles of genes important to Treg function, including the forkhead P3 (Foxp3) transcription factor. (bvsalud.org)
• This view reflects the amazing conservation of genetic apparatus that has been discovered across the Bilateria, particularly of genes encoding transcription factors and signaling molecules. (silverchair.com)

Members1

• Its members are X factor (HEMIN) independent and variably dependent on V factor (NAD). (nih.gov)

Development1

• Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. (thermofisher.com)