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  • Receptors
  • NOD B1a cells had a naturally increased pattern of activation, expressed higher levels of toll-like-receptors ( Tlrs ) and responded to TLR stimulation in vitro with higher proliferation and increased capacity to secrete anti-type-1-diabetes-related IgM, but produced lower amounts of IL10. (springer.com)
  • They are phagocytic, non-specific esterase positive and they express macrophage Mac-1 antigens and Fc receptors. (atcc.org)
  • Phagocytosis
  • Demyelination of axons in the central nervous system (CNS) during multiple sclerosis (MS) and its animal model experimental allergic encephalomyelitis (EAE) is a result of phagocytosis and digestion by macrophages (M phi) and the local release of inflammatory mediators like tumor necrosis factor-alpha (TNF-alpha) and nitric oxide (NO). We have investigated the process of myelin phagocytosis by M phi in vitro using flow cytometric analysis. (edu.au)
  • Monocytes
  • When 1 alpha,25-dihydroxyvitamin D(3) (D(3)) induces HL60 cells to differentiate to monocytes, a burst of approximately three shortened cell cycles ("maturation divisions") precedes exit from cell cycle and completion of maturation. (biomedsearch.com)
  • skeletal
  • 1. A myocardial graft in an animal, comprising: a stable graft of skeletal myoblasts or cardiomyocytes incorporated in myocardial tissue of said animal. (freepatentsonline.com)
  • 3. The myocardial graft of claim 1 wherein said stable graft comprises skeletal myoblasts. (freepatentsonline.com)
  • During postischaemic revascularization neutrophil-endothelial adhesion in the skeletal muscle microcirculation, promoted by the neutrophil adhesion molecule Mac-1, may impair muscle blood flow and release oxygen free radicals and proteolytic enzymes which causes further tissue injury. (ucl.ac.uk)
  • determinant
  • Recent intravital microscopic studies have provided compelling evidence that activated neutrophils adherent to inflamed ECs can support homotypic and heterotypic cell-cell interactions and that platelet-neutrophil aggregation on activated ECs is the crucial determinant of microvascular occlusion during vascular inflammation ( Fig. 1 ) [ 8 , 9 ]. (pubmedcentralcanada.ca)
  • Infection
  • AMJ2-C8 ( ATCC CRL-2455 ) and AMJ2-C11 ( ATCC CRL-2456 ) are cloned, continuous, alveolar macrophage (AM) cell lines generated from C57BL6J mice by in vitro infection with the J2 retrovirus carrying the v-raf and v-myc oncogenes. (atcc.org)
  • Tissue
  • 5. The myocardial graft of claim 1 wherein said stable graft delivers recombinant molecules to the myocardial tissue. (freepatentsonline.com)
  • conditions
  • DCs precursors Immature DCs DCs progenitors Mature DCs In inflammatory conditions, immature DC migrate to draining lymph nodes where after maturation (mature DC), they prime the rare circulating naïve antigen-specific lymphocytes. (slideplayer.com)
  • known
  • Studies on the tumoricidal properties of these cell lines demonstrated differences in their response to a panel of known macrophage activators. (atcc.org)
  • Factors
  • The Gram-positive bacterium Staphylococcus aureus causes invasive disease and can infect nearly all host tissues by combating the host immune system with an array of virulence factors ( 1 ). (pnas.org)
  • type
  • Defects in ITGB2 are the cause of leukocyte adhesion deficiency type 1 (LAD1) [MIM: (abcam.com)
  • The chimeric transfectants, K562-α4β7(αLβ2c) and K562-α4β7(αMβ2tc), also adhered to MAdCAM-1, and the extent of adhesion was very similar for chimeric and wild-type α4β7 transfectants. (nih.gov)
  • this provides an early mechanism that contributes to diabetes in a mouse model of type 1 diabetes. (springer.com)
  • model
  • In an aortic transplantation model, we have previously analysed the early adhesion process (7.5 min to 24 h) and the impact of cold ischaemia time (1-24 h) upon transplant arteriosclerosis during the first 2 months after transplantation in the rat. (diva-portal.org)