• these substances, in both rodents and humans. (cdc.gov)
  • Humic substances (HSs) are the natural organic polyelectrolytes formed from the biochemical weathering of plant and animal remains. (princeton.edu)
  • Here we argue that the available evidence does not support the formation of large-molecular-size and persistent 'humic substances' in soils. (nature.com)
  • Sutton, R. & Sposito, G. Molecular structure in soil humic substances: the new view. (nature.com)
  • Burdon, J. Are the traditional concepts of the structures of humic substances realistic? (nature.com)
  • Due to their very complex molecular structure, humic substances, including humin, do not correspond to pure substances but consist of a mixture of many compounds that remain very difficult to characterize even using modern analytical techniques. (wikipedia.org)
  • Humic substances (HS) are compounds with a complicated structure, present in the humus soil layer, water, lake sediments, peat, brown coal and shales. (peerj.com)
  • Macromolecular Substances" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (uchicago.edu)
  • Organic matter Soil organic matter Humus Humic substance Rice, James A. "Humin" Soil Science 2001, vol. 166(11), pp. 848-857. (wikipedia.org)
  • Enzyme inhibitors are a chemically diverse set of substances that range in size from organic small molecules to macromolecular proteins . (wikipedia.org)
  • It is an organic substance that is found in Canada and elsewhere primarily as a chemical intermediate in a variety of industries. (gc.ca)
  • Their macromolecular structure and chemistry determine their role in biogeochemical processes. (princeton.edu)
  • In situ spectromicroscopic evidence showed that the HS macromolecular structures (size and shape) vary as a function of HS origin (soil versus fluvial), solution chemistry, and the associated mineralogy. (princeton.edu)
  • Humins are carbon-based macromolecular substances, that can be found in soil chemistry or as a by-product from saccharide-based biorefinery processes. (wikipedia.org)
  • The macromolecular structural changes of HSs are likely to modify contaminant solubility, biotransformation, and the carbon cycle in soils and sediments. (princeton.edu)
  • In biological systems macromolecular substances usually can be visualized using ELECTRON MICROSCOPY and are distinguished from ORGANELLES by the lack of a membrane structure. (uchicago.edu)
  • The Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) mandates that the Agency for Toxic Substances and Disease Registry (ATSDR) shall assess whether adequate information on health effects is available for the priority hazardous substances. (cdc.gov)
  • Half maximal inhibition concentration (IC 50 ) is a measure of the potency of a substance in inhibiting a specific biological or biochemical function. (researchgate.net)
  • The methyl esters of methacrylic acid that polymerize easily and are used as tissue cements, dental materials, and absorbent for biological substances. (ouhsc.edu)
  • Humins are not considered to be a dangerous substance according to officially recognized hazardous material classification systems based on physical-chemical properties such as flammability, explosiveness, susceptibility to oxidation, corrosiveness or eco-toxicity. (wikipedia.org)
  • This substance was identified in the categorization of the Domestic Substances List (DSL) as a high priority for action under the Challenge. (gc.ca)
  • On the basis of the carcinogenic potential of 2-nitrotoluene, for which there may be a probability of harm at any exposure level, it is concluded that 2-nitrotoluene is a substance that may be entering the environment in a quantity or concentration or under conditions that constitute or may constitute a danger in Canada to human life or health. (gc.ca)
  • The Act further directs that where feasible, ATSDR shall develop methods to determine the health effects of substances in combination with other substances with which they are commonly found. (cdc.gov)
  • Within the broad vibrational spectra of C-D bonds, we discover lipid-, protein-, and DNA-specific Raman shifts and develop spectral unmixing methods to obtain C-D signals with macromolecular selectivity. (nih.gov)
  • This graph shows the total number of publications written about "Macromolecular Substances" by people in this website by year, and whether "Macromolecular Substances" was a major or minor topic of these publications. (uchicago.edu)
  • Below are the most recent publications written about "Macromolecular Substances" by people in Profiles. (uchicago.edu)
  • Recent evidence indicates that other proteins are associated with connexins at gap junctions, and we have termed this macromolecular complex the Nexus. (elsevierpure.com)
  • To identify potential scaffolding proteins that could organize a macromolecular signaling complex involving the CaR and Kir4.2, we used yeast two-hybrid cloning with the COOH-terminal 125 amino acids (AA) of Kir4.2 as bait to screen a human kidney cDNA library. (elsevierpure.com)
  • The in vitro assay system is composed of two components, a synthetic macromolecular biobarrier and a Chemical Detection System (CDS). (nih.gov)
  • this term includes gene products that are parts of macromolecular complexes\, by the definition that all members of a complex normally copurify under all except extreme conditions. (bionity.com)
  • In this work, we present an approach for 3D single particle analysis in localization microscopy which hugely increases signal-to-noise ratio and resolution and enables determining the symmetry groups of macromolecular complexes. (tudelft.nl)
  • Towards this, macromolecular complexes composed of Munc18c, Doc2b and Munc18-1 were detected in β-cells. (ttu.edu)
  • In biological systems macromolecular substances usually can be visualized using ELECTRON MICROSCOPY and are distinguished from ORGANELLES by the lack of a membrane structure. (nih.gov)
  • Due to their very complex molecular structure, humic substances, including humin, do not correspond to pure substances but consist of a mixture of many compounds that remain very difficult to characterize even using modern analytical techniques. (wikipedia.org)
  • Several ecologically relevant aspects of soil organic matter (SOM), like the sorption of organic compounds and the water uptake kinetics, can only be explained in terms of the macromolecular structure of the humic substances. (tu-berlin.de)
  • 1 Dynamics of Macromolecular Assembly Section, Laboratory of Cellular Imaging and Macromolecular Biophysics, National Institutes of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland, USA. (nih.gov)
  • Conjugates of anticancer agents and polymers: advantages of macromolecular therapeutics in vivo. (ox.ac.uk)
  • Scholars@Duke publication: Revealing the macromolecular targets of complex natural products. (duke.edu)
  • Gout Tool is a macromolecular complex of natural anti-inflammatory substances and vitamins attached to natural carriers, serving as an ideal combination for essential micronutrients and antioxidants, free of side effects. (beautybridge.com)
  • This symposium will describe the current state of research on the structural analysis of large macromolecular assemblies and the most important challenges that must be met to take our understanding to the next level. (nih.gov)
  • Corrositex® is a validated and accepted (1)(2)(3)(4) in vitro test method that assesses if a substance can produce skin corrosion. (nih.gov)
  • In this paper, we discuss several methods of structure refinement that promise to increase the accuracy of macromolecular structures determined by NMR. (nih.gov)
  • Certainly by changing some atoms in large molecules we can subtly change the properties of that substance, and so, knowledge of the atomic structure is important but more secondary. (yale.edu)
  • The unique processing of the product's macromolecular structure ensures correct absorption which aids in natural increased immune response and overall healing abilities of the body. (beautybridge.com)
  • Humins are not considered to be a dangerous substance according to officially recognized hazardous material classification systems based on physical-chemical properties such as flammability, explosiveness, susceptibility to oxidation, corrosiveness or eco-toxicity. (wikipedia.org)
  • Test substances are applied to the upper surface of the macromolecular biobarrier. (nih.gov)
  • Corrosive substances are able to disrupt the integrity of the biobarrier, leading to the penetration of the test substance through the biobarrier into the CDS located beneath (6)(8). (nih.gov)
  • The presence of the test substance in the CDS results in a color change that is detected visually. (nih.gov)
  • the more corrosive a test substance, the shorter the time required to affect a color change. (nih.gov)
  • Prior to performing Corrositex®, a test substance is evaluated as to its compatibility with the CDS. (nih.gov)
  • A sample of the test substance is placed in a small amount of CDS fluid. (nih.gov)
  • Corrositex® (i.e., the test substance qualifies). (nih.gov)
  • If the test substance does not cause a color change, it must be tested by another method. (nih.gov)
  • Qualified test substances are classified into one of four categories by a screening test that is supplied with the assay kit. (nih.gov)
  • The category that a test substance is assigned to will determine how the breakthrough time (if one occurs) will be interpreted. (nih.gov)
  • A test substance is assigned to a category based on its ability to induce a pH change in one of two defined buffers. (nih.gov)
  • In Corrositex®, a test substance is assigned to an UN transportation Packing Group by considering the pH category that is assigned based on the result obtained in the screening test and by the time it takes for the test substance to penetrate the biobarrier. (nih.gov)
  • Category A1 and B1 test substances are assigned to Group I if, after application to the biobarrier, a color change is observed between zero and three minutes, to Group II if a color change is observed after three minutes and up to one hour, and to Group III if a color change is observed after one hour and up to four hours. (nih.gov)
  • It is known that the conformation of the macromolecular SOM network is distinctly affected by the water status in soil. (tu-berlin.de)
  • Polymeric nanoparticles are solid, colloidal particles consisting of macromolecular substances that vary in size from 10 to 1000 nm. (medscape.com)
  • One critical area is large macromolecular assemblies, which accomplish many of the core functions of the cell. (nih.gov)
  • Category A1 substances produce a large change in pH when they are added to the acid buffer. (nih.gov)
  • Due to its extremely small polyporous filter elements, any harmful substances, small molecule or macromolecular, will be removed effectively. (hgrigging.com)
  • Packing Groups are assigned according to the degree of danger presented by the corrosive substance. (nih.gov)
  • We do indeed look at bonding and maybe get into the shape of a molecule and how that might influence the properties of a substance. (yale.edu)
  • Category A2 substances produce little or no pH changes when added to the acid buffer and, therefore, little or no color change in the buffer solution is observed. (nih.gov)
  • Lungs: Cellular respiration release CO 2 as excretory substance, which is eliminated outside by respiratory process in the lungs. (rbsesolutions.com)