• ABSTRACT Fluoroquinolone and macrolide antibiotics are generally considered as first-line drugs for the treatment of severe campylobacteriosis. (who.int)
  • Macrolide antibiotics (erythromycin) block bacterial specific ribosomes and prevent them from building proteins. (pethealthandnutritioncenter.com)
  • Quinolone antibiotics (ciprofloxacin/levofloxacin) work by causing bacteria DNA strands to break. (pethealthandnutritioncenter.com)
  • The authors also traced the presence of genes conferring resistance to macrolides and quinolones, which are among the most critically important antibiotics for human health. (medicalxpress.com)
  • Pipemidic acid is a pyridopyrimidine antibiotic with similar properties to quinolone antibiotics. (goldbio.com)
  • Patients with history of treatment with macrolide or quinolone antibiotics, anti-tuberculosis medication, or immuno-modulatory drugs including corticosteroids within one month before recruitment. (who.int)
  • It is a good alternative antibiotic for patients allergic to or intolerant of the macrolide class. (medscape.com)
  • Mutations causing resistance to azithromycin-a widely used macrolide antibiotic-have emerged at least seven times in the past 20 years. (medicalxpress.com)
  • Quinolones, triazoles, metronidazole, linezolid, and clarithromycin accounted for 173 (25.7%) of 673 prescribed antimicrobials, but were responsible for 141 (92.1%) of 153 interactions. (researchgate.net)
  • RÉSUMÉ Les antibiotiques tels que les fluoroquinolones et les macrolides sont généralement indiqués dans le traitement de première ligne des cas sévères de campylobactériose. (who.int)
  • In case Chlamydia suis is resistant to those, quinolones or macrolides could be the second choice. (biomin.net)
  • Quinolone-resistant strains accounted for more than 85% of S. typhi in Bangladesh by the early 2000s, increasing to more than 95% in India, Pakistan, and Nepal by 2010. (medicalxpress.com)
  • For example, gene mutations giving resistance to quinolones have arisen and spread at least 94 times since 1990, with nearly all of these (97%) originating in South Asia. (medicalxpress.com)
  • Patients with QTc prolongation >450 ms on ECG or taking other medication known to prolong the QTc interval, such as quinolones. (who.int)
  • Mycoplasma genitalium has a tendency to develop macrolide and quinolone resistance.We investigated the microbiological cure rate of a 7 day course of sitafloxacin for the treatment of rectal and urogenital infections in MSM.This open-label, prospective cohort study was conducted at the National Center for Global Health and Medicine, Tokyo, Japan from January 2019 to August 2022. (stanford.edu)
  • Sputum conversion with macrolide-resistant MAC occurred in 11 of 14 (79%) patients who received more than 6 mo of injectable aminoglycoside therapy and lung resection, compared with 2 of 37 (5%) who did not. (nih.gov)
  • The other 22 isolates were positive to resistance genes to aminoglycoside, macrolides/lincosamides and chloramphenicol and showed mutations in the QRDR of the gyrA gene. (biomedcentral.com)
  • Aminoglycoside and Quinolone resistance was also high at 49.2% and 41.3% respectively. (bvsalud.org)
  • The result showing that quinolone and tetracycline are associated with an increased risk of miscarriage is "concordant with guidelines that say that they should not be used during pregnancy," Bérard noted. (wxyz.com)
  • Macrolide-susceptible cases received 2.5 g azithromycin (1 g, then 500 mg daily for 3 days), and resistant cases moxifloxacin (400 mg daily, 7 days). (nih.gov)
  • Our data show stable macrolide activity against Campylobacter spp. (nih.gov)
  • Salmonella and Campylobacter ) has already been reported, but the scope of the problems still needs to be identified and the links between quinolone use in animals and the occurrence of problems in infectious disease treatment in humans elucidated. (who.int)
  • Genes resistant to β-lactams and quinolones were the two most abundant types of ARGs in all the cities studied. (phys.org)
  • Characterize patients, treatment, and isolates in macrolide-resistant MAC lung disease. (nih.gov)
  • Review the conditions and extent of use of the various quinolones in humans and in food animals. (who.int)
  • In patients receiving systemically administered quinolones, serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported, some following the first dose. (medicines.org.uk)
  • The objective of this study was to estimate the risk of macrolides and amoxicillin/clavulanate (AMC) on DILI. (nih.gov)
  • For instance, data from China estimate annual quinolone consumption in animals in China alone to be in the range of 470 tonnes (annual consumption in human medicine in China: about 1,350 tonnes). (who.int)
  • ParC mutations were present in 22% of macrolide-resistant cases. (nih.gov)
  • Currently, several quinolones are available for treatment of animals, poultry and fish in many countries in the world. (who.int)
  • Hypersensitivity to the active substance, to other quinolones, or to any of the excipients listed in section 6.1. (medicines.org.uk)
  • However, available usage data, particularly for non-proprietary quinolones, are known to be grossly incomplete. (who.int)
  • Quinolones have broad activity against gram-positive and gram-negative aerobic organisms. (medscape.com)
  • Macrolide-resistant MAC lung disease requires aggressive drug and surgical therapy for cure. (nih.gov)
  • 50 tonnes for proprietary products (mainly USA, European Union, Japan, South Korea) and, because of their lower prices, about 70 tonnes for generic quinolones. (who.int)