LysosomesLysosome-Associated Membrane GlycoproteinsEndosomesAcid PhosphataseEndocytosisPhagosomesCathepsin DAutophagyLysosomal-Associated Membrane Protein 2Microscopy, ElectronCathepsinsProtein TransportVacuolesChediak-Higashi Syndromebeta-N-AcetylhexosaminidasesReceptor, IGF Type 2Cell FractionationGolgi ApparatusBiological TransportChloroquinerab GTP-Binding ProteinsSubcellular FractionsMannosephosphatesOrganellesGlucuronidaseMucolipidosesOrganoidsLysosomal Storage DiseasesCathepsin BCell LineCell CompartmentationIntracellular MembranesHydrogen-Ion ConcentrationLiverAndrostenesCell MembraneHydrolasesArylsulfatasesHistocytochemistryCells, CulturedAcetylglucosaminidaseMultivesicular BodiesAmmonium ChlorideMicroscopy, FluorescenceHorseradish PeroxidaseMembrane FusionMacrophagesHexosaminidasesVesicular Transport ProteinsMicroscopy, ImmunoelectronCathepsin LAsialoglycoproteinsCytoplasmic GranulesFibroblastsAntigens, CD63LeupeptinsCystinosisPhagocytosisMicroscopy, ConfocalMacrolidesSulfatasesPepstatinsExocytosisMembrane ProteinsFetuinsrab5 GTP-Binding ProteinsAdaptor Protein Complex 3KineticsHeLa CellsCentrifugation, Density GradientCytoplasmMembrane GlycoproteinsSaposinsEndoplasmic ReticulumNiemann-Pick DiseasesEndosomal Sorting Complexes Required for TransportProteinsCricetinaeVacuolar Proton-Translocating ATPasesDextransProteolysisCathepsin CMolecular Sequence DataMelanosomesAmino Acid SequenceTransport VesiclesMonensinCytoplasmic VesiclesClathrin