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  • Antibody
  • Background: Normal Rabbit IgG is an isotype control antibody, which is used to estimate the non-specific binding of target primary antibodies due to Fc receptor binding or other protein-protein interactions. (cellsignal.com)
  • This Cell Signaling Technology antibody is conjugated to Alexa Fluor® 647 fluorescent dye and tested in-house for direct flow cytometry and immunofluorescent analysis in cells transfected with Myc-tagged protein. (cellsignal.com)
  • receptor
  • HsAtg4B/HsApg4B/autophagin-1 cleaves the carboxyl termini of three human Atg8 homologues and delipidates microtubule-associated protein light chain 3- and GABAA receptor-associated protein-phospholipid conjugates. (springer.com)
  • Adenoviruses bind to a cell receptor via the fiber protein. (asm.org)
  • Some picornaviruses undergo receptor-mediated conformational changes and form altered particles in which the hydrophobic amino terminus of virus protein 1 (VP1) is exposed on the virion surface ( 6 ). (asm.org)
  • The virus and its receptor enter host cells via dynamin-dependent and clathrin-mediated endocytosis ( 2 , 3 , 9 , 10 , 26 ). (asm.org)
  • autophagosome
  • Mizushima N, Yoshimori T, Ohsumi Y. The role of atg proteins in autophagosome formation. (springer.com)
  • Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum. (springer.com)
  • LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. (springer.com)
  • cDNA
  • The lab cloned encoding DNAs for each of these proteins from avian cDNA libraries and expressed these DNAs in tissue cultured mammalian cells, where each avian protein was correctly sorted and localized. (searlescholars.net)
  • Species
  • The survival of these cells depends on their ability fo active autophagy, reprogramme its metabolism, and control the production of toxic compounds, such as reactive oxygen species ROS and misfolded proteins. (wikibooks.org)
  • Human
  • Monoclonal antibodies to a variety of extracellular matrix proteins and to human acetylcholinesterase were also developed and given to the Developmental Studies Hybridoma Bank. (searlescholars.net)
  • Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD caused by enterovirus-71 and possibly by coxsackievirus A16. (thermofisher.com)
  • LAMP2A
  • Our secondary objectives were to examine the associations of lamp2's CSF concentration with CSF levels of the molecular chaperone heat shock 70-kDa protein (HSPA8), which interacts with lamp2a in CMA, and oxidative stress markers 8-hydroxy-2′-deoxyguanosine (8-OHdG), 8-isoprostane (8-ISO) and Total Antioxidant Capacity (TAC) in healthy subjects. (frontiersin.org)
  • variants
  • Heterogeneous impact of type 2 diabetes mellitus-related genetic variants on gestational glycemic traits: review and future research needs. (nih.gov)
  • cardiomyopathy
  • [2] In general, the condition is characterized by cardiomyopathy , weakening of the skeletal muscles, and intellectual disability . (nih.gov)