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  • Recombinant
  • Abgent has over fifteen years of experience producing recombinant proteins in E. coli and mammalian cells (CHO and HEK293, etc), and we have added a powerful yeast expression platform to our menu of services. (abgent.com)
  • peptides
  • Check out links to articles that cite our custom service antibodies, peptides, and proteins in major peer-reviewed journals, organized by research category. (abgent.com)
  • fetus
  • Intrauterine growth restriction (IUGR), also known as fetal growth restriction, refers to a fetus that has failed to reach his or her genetic growth potential in utero. (jimmunol.org)
  • Fetus lysate (7 Day Fetus) was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin). (creativebiomart.net)
  • ubiquitin ligase
  • These data suggest that ZNRF proteins play a role in the establishment and maintenance of neuronal transmission and plasticity via their ubiquitin ligase activity. (jneurosci.org)
  • mammalian
  • Here we designate ZNRF proteins as a family of molecules by the identification of a second mammalian protein, ZNRF2, which is highly similar to ZNRF1 in the zinc finger-RING finger region. (jneurosci.org)
  • Species
  • Proteins homologous to ZNRF1 are present in a wide range of species including Caenorhabditis elegans and Drosophila . (jneurosci.org)
  • cellular
  • 6. The method of claim 1, wherein said lysate comprises one or more cellular components. (patentsencyclopedia.com)
  • PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. (abcam.com)
  • Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. (abcam.com)
  • constitute
  • Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. (acris-antibodies.com)
  • degradation
  • The classical view of ubiquitination is to target proteins for degradation by a multi-subunit, ATP-dependent protease termed the proteosome ( Pickart, 2001 ). (jneurosci.org)
  • Proteins typically are marked for proteolytic degradation by attachment of multiubiquitin chains. (pnas.org)
  • proteolytic
  • Tsai and Oroszlan (19) have described proteolytic processing and novel glycosylation pathways for retroviral envelope proteins and characterized the env precursor polyprotein of avian reticuleondotheliosis virus (REV-A) as being modified by unusually large sialic acid-rich complex-type carbohydrate moieties (19). (google.ca)
  • amino
  • Leucine (Leu), an essential branched-chain amino acid (BCAA), is a nutrient that increases the birth weight of newborns and prevents the development of a fetal growth defect in pregnancies where fetal growth is abnormal ( 6 , 7 ). (diabetesjournals.org)
  • zinc
  • We previously identified ZNRF1/nin283, a protein with a unique, evolutionarily conserved C-terminal domain containing a juxtaposed zinc finger/RING finger combination. (jneurosci.org)
  • The RING finger is a zinc-binding protein domain that was initially characterized as a protein interaction domain ( Borden, 1998 ). (jneurosci.org)
  • Furthermore
  • Furthermore, we examined KAI1 protein expression immunohistochemically in specimens from 81 patients with breast cancer and then correlated the findings with the clinical and histopathological parameters of the patients. (aacrjournals.org)
  • regulation
  • The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. (abcam.com)
  • The widespread expression of ZNRF proteins in the nervous system along with their involvement in exocytosis in presynaptic terminals that we demonstrate here suggests that they may participate in the regulation of proteins involved in presynaptic exocytosis and/or synaptic vesicle recycling. (jneurosci.org)