Patients With Lymphomatoid PapulosisLymphomaLymphomas1968Lymphoproliferative disorderMycosis fungoidesDifferential diagnosisSubtypesLesionsEruptionChildhoodAtypicalClinicalVariantLocalized to the faceCasesSkinTreatmentRareUnknownPatients with lymphomatoid papulosisAnaplasticCD30ClinicopathologicDermatolMycosisTypeUpdate and reviewSearchConditions
Patients With Lymphomatoid Papulosis2
- A distinctive immunologic phenotype was demonstrated for the characteristic large atypical cells in the skin lesions of 9 patients with lymphomatoid papulosis (LP). Co-expression of Hodgkin's disease (HD)-associated antigen(s) Ki-1, and often Leu-M1, with helper T-cell antigens T11, T4, and T3 and cellular activation antigens Tac, Ia, and T9 was the most common phenotype, observed in 6 of 9 cases. (johnshopkins.edu)
- Frequency and Risk Factors for Associated Lymphomas in Patients With Lymphomatoid Papulosis. (bvsalud.org)
Lymphoma8
- Lymphomatoid papulosis (LyP) is a chronic papulonecrotic or papulonodular skin disease with histologic features suggestive of a malignant lymphoma. (medscape.com)
- It classifies lymphomatoid papulosis as an indolent T-cell lymphoproliferative disorder of the skin, under primary cutaneous CD30 + T-cell lymphoproliferative disorders, along with primary cutaneous anaplastic large cell lymphoma (pcALCL). (medscape.com)
- Lymphomatoid papulosis (LyP) is a recurrent, chronic, self-healing eruption that exists on a continuum with primary cutaneous anaplastic large cell lymphoma (C-ALCL). (logicalimages.com)
- Lymphomatoid papulosis (LyP) and primary cutaneous anaplastic large cell lymphoma (ALCL) comprise a disease spectrum known as primary cutaneous CD30+ T-cell lymphoproliferative disorders (CD30+ LPD). (nextstepsinderm.com)
- EORTC, ISCL, and USCLC consensus recommendations for the treatment of primary cutaneous CD30-positive lymphoproliferative disorders: lymphomatoid papulosis and primary cutaneous anaplastic large-cell lymphoma. (qxmd.com)
- Primary cutaneous CD30(+) lymphoproliferative disorders (CD30(+) LPDs) are the second most common form of cutaneous T-cell lymphomas and include lymphomatoid papulosis and primary cutaneous anaplastic large-cell lymphoma. (qxmd.com)
- In lymphomas I have conducted studies in rare aggressive primary cutaneous tumors such as gamma/delta T cell lymphoma (expanding the description of the epidermotropic variant) as well as more indolent entities such as lymphomatoid papulosis (type D) and CD4-positive small to medium size T cell lymphoproliferative disorders. (mdanderson.org)
- In dermatology, LDH is characteristically part of the initial staging work-up of cutaneous lymphoma (including lymphomatoid papulosis) and melanoma. (aad.org)
Lymphomas4
- However, the classification system for cutaneous lymphomas has evolved rapidly, and, during consensus meetings in 2003-2004, the World Health Organization-European Organization for Research and Treatment of Cancer (WHO-EORTC) classification grouped lymphomatoid papulosis among the indolent cutaneous T-cell lymphomas. (medscape.com)
- In a 2005 study, the 30M377 allelic form of the CD30 promoter microsatellite repressive element was associated with the development of lymphomatoid papulosis, and the 30M362 allelic form was associated with progression to other CD30 + lymphomas in lymphomatoid papulosis patients. (medscape.com)
- Lymphomatoid papulosis: Treatment response and associated lymphomas in a study of 180 patients. (nih.gov)
- Lymphomatoid papulosis/Other primary cutaneous lymphomas. (ejpd.com)
19681
- Lymphomatoid papulosis (LyP) is a disorder described by Macaulay in 1968 as a continuous self-healing, papular eruption, clinically benign and histologically malignant [ 1 ]. (cdlib.org)
Lymphoproliferative disorder1
- Lymphomatoid papulosis (LyP) is a CD30+ T-cell lymphoproliferative disorder (LPD) presenting as a recurrent eruption of papules and nodules which resolve spontaneously. (nextstepsinderm.com)
Mycosis fungoides2
- A 47-year-old black man had typical papulonodular lesions of lymphomatoid papulosis (LyP) with concurrent plaque-stage mycosis fungoides (MF). (jamanetwork.com)
- We examined the immune activation in 20 patients with mycosis fungoides, 6 patients with erythrodermia of unknown origin (Pré-Sézary's syndrome), 5 with lymphomatoid papulosis, 4 with parapsoriasis, 2 with Sézary's syndrome, and 2 with actinic reticuloid, by measuring soluble interleukin-2 receptor levels in serum. (medicaljournals.se)
Differential diagnosis1
- Histopathological aspects and differential diagnosis of CD8 positive lymphomatoid papulosis. (nih.gov)
Subtypes2
- Lymphomatoid papulosis: reappraisal of clinicopathologic presentation and classification into subtypes A, B, and C". Arch Dermatol. (wikipedia.org)
- [ 6 ] The 2016 classification described new subtypes of lymphomatoid papulosis with similar clinical behavior but atypical histologic/immunophenotypic features. (medscape.com)
Lesions1
- Lymphomatoid papulosis is part of a spectrum of CD30 (Ki-1)-positive cutaneous lymphoproliferative diseases (CD30 + LPDs), including lymphomatoid papulosis, pcALCL, and borderline CD30 + lesions. (medscape.com)
Eruption1
- Other events with a possible relation to TNF-α-blocking therapy included vasculitis, psoriasis, drug-induced systemic lupus erythematosus, dermatomyositis, and a lymphomatoid-papulosis-like eruption. (biomedcentral.com)
Childhood2
Atypical1
- A variant of lymphomatoid papulosis characterized by an epidermotropic infiltrate composed of small atypical cerebriform-like lymphocytes. (nih.gov)
Clinical1
- Due to the typical waxing and waning clinical course, lymphomatoid papulosis was previously considered a pseuodolymphomatous inflammatory process. (medscape.com)
Variant1
- El-Darouti et al reported on a 7-year study of a hypopigmented disorder that the researchers believe should be classified as a new variant of parapsoriasis en plaque. (medscape.com)
Localized to the face1
- We report a case of lymphomatoid papulosis (LyP) localized to the face. (cdlib.org)
Cases3
- The overall prevalence rate of lymphomatoid papulosis is estimated at at least 1.2 cases per 1,000,000 population. (wikipedia.org)
- Spontaneous regression of lymphomatoid papulosis is seen almost universally, whereas regression occurs in approximately 25% of pcALCL cases. (medscape.com)
- 2] Other cases have given rise to lymphomatoid papulosis. (medscape.com)
Skin2
- Lymphomatoid papulosis (LyP) is a rare skin disorder. (wikipedia.org)
- Skin biopsy was consistent with lymphomatoid papulosis (LyP) Type D, a recently recognized subtype of LyP that is distinguished histologically by marked epidermotropism and a perivascular infiltrate of medium-sized pleomorphic lymphocytes with a cytotoxic phenotype (CD3+, CD8+). (duke.edu)
Treatment1
- Cartas Cient ficas: Resultados a mediano plazo en el tratamiento endovascular del paciente claudicante / Scientific letters: Medium-term results in the endovascular treatment of claudicant patients. (bireme.br)
Rare1
- A rare case of ulcerative proctitis associated with type B lymphomatoid papulosis and superimposed human cytomegalovirus infection. (nih.gov)
Unknown1
- The pathophysiology of CD30 + LPDs, including lymphomatoid papulosis (LyP), is largely unknown. (medscape.com)
Patients with lymphomatoid papulosis4
- Beljaards RC, Willemze R. The prognosis of patients with lymphomatoid papulosis associated with malignant lymphomas. (medscape.com)
- Frequency and prognosis of associated malignancies in 504 patients with lymphomatoid papulosis. (medscape.com)
- Frequency and Risk Factors for Associated Lymphomas in Patients With Lymphomatoid Papulosis. (bvsalud.org)
- DUSP22-IRF4 rearrangements have been also reported in patients with lymphomatoid papulosis (LyP). (neogenomics.com)
Anaplastic12
- Epstein-Barr virus in CD30 anaplastic large cell lymphoma involving the skin and lymphomatoid papulosis in South Korea. (medscape.com)
- EORTC, ISCL, and USCLC consensus recommendations for the treatment of primary cutaneous CD30-positive lymphoproliferative disorders: lymphomatoid papulosis and primary cutaneous anaplastic large-cell lymphoma. (medscape.com)
- CD30+ cutaneous lymphoproliferative disorders: the Stanford experience in lymphomatoid papulosis and primary cutaneous anaplastic large cell lymphoma. (medscape.com)
- 6. [Neutrophil-rich, anaplastic CD30+ T cell lymphoma in conjunction with lymphomatoid papulosis]. (nih.gov)
- 16. Molecular evidence for a clonal relationship between lymphomatoid papulosis and Ki-1 positive large cell anaplastic lymphoma. (nih.gov)
- 17. A comparison of clinical, morphological and immunohistochemical features of lymphomatoid papulosis and primary cutaneous CD30(Ki-1)-positive anaplastic large cell lymphoma. (nih.gov)
- The excisional biopsy indicated that "The differential diagnosis includes lymphomatoid papulosis type C, primary cutaneous anaplastic large cell lymphoma, and skin involvement by systemic anaplastic large cell lymphoma. (cancer.org)
- An unusual course was observed in a patient with indolent T-prolymphocytic leukaemia (T-PLL) who subsequently developed mycosis fungoides (Mf), lymphomatoid papulosis (LyP) and cutaneous CD30+ anaplastic large cell lymphoma (ALCL). (nih.gov)
- Other types of CTCL include: lymphomatoid papulosis, peripheral T-cell lymphoma, cutaneous anaplastic large cell lymphoma, adult T-cell leukaemia /lymphoma, lymphomatoid granulomatosis, granulomatous slack skin disease, and pagetoid reticulosis, to name a few. (leukaemia.org.au)
- Primary cutaneous CD30- positive large cell lymphoma (CD30+ PCLCL) represents a spectrum of disease, with lymphomatoid papulosis (LyP) at the benign end, and primary cutaneous anaplastic large cell lymphoma (PCALCL) at the other. (journalcra.com)
- After a thorough clinicopathological correlation a diagnosis of CD30+PCLCL - lymphomatoid papulosis was made in first case and CD30+ PCLTCL - Anaplastic type in second. (journalcra.com)
- Cutaneous CD30+ lymphoproliferative disorder (CD30+LPDs), including lymphomatoid papulosis (LyP) and primary cutaneous anaplastic large-cell lymphoma (PCALCL), comprises the second most common group of cutaneous T cell lymphoma. (refine.bio)
CD305
- 5. Pityriasis lichenoides et varioliformis acuta with numerous CD30(+) cells: a variant mimicking lymphomatoid papulosis and other cutaneous lymphomas. (nih.gov)
- 11. CD30 antigen expression in cutaneous inflammatory infiltrates of scabies: a dynamic immunophenotypic pattern that should be distinguished from lymphomatoid papulosis. (nih.gov)
- 12. CD8-positive lymphomatoid papulosis (type D): Some lesions may lack CD30 expression and overlap histologically with mycosis fungoides. (nih.gov)
- 14. Primary CD30-positive cutaneous T-cell lymphomas and lymphomatoid papulosis frequently express cytotoxic proteins. (nih.gov)
- Primary cutaneous Compact disc30-positive T-cell lymphoproliferative disorders (LPDs), which take into account 30% of cutaneous T-cell lymphomas (CTCLs), express CD30 always, aside from a uncommon subtype called type B lymphomatoid papulosis (LyP) [42]. (spierarchitecturalarts.com)
Clinicopathologic2
- Lymphomatoid papulosis: reappraisal of clinicopathologic presentation and classification into subtypes A, B, and C". Arch Dermatol. (wikipedia.org)
- To study the clinicopathologic characteristics and immunophenotype of lymphomatoid papulosis(LyP), followed by exon mutation analysis with focus on gene mutations involved in apoptosis pathway and other possible pathogenic genes. (nih.gov)
Dermatol1
- Regional lymphomatoid papulosis, type A. Int J Dermatol. (uchicago.edu)
Mycosis1
- It is not Mycosis Fungoides and it is closely related to Lymphomatoid Papulosis. (cancer.org)
Type1
- Rajashekara Swamy M, Pollock S, J Goldberg L, Shen L. A case of lymphomatoid papulosis type E in a young adult: An uncommon entity. (bu.edu)
Update and review1
- Lymphomatoid papulosis: an update and review. (medscape.com)
Search1
- In search of prognostic indicators for lymphomatoid papulosis: A retrospective study of 123 patients. (medscape.com)
Conditions1
- In the paper, the authors note that infections caused by Staphylococcus aureus, Bacillus anthracis, Borrelia burgdorferi, Sporothrix schenckii, the herpes zoster virus, and even lymphoproliferative conditions such as lymphomatoid papulosis have been misdiagnosed as bites from the spider Loxosceles recluse , commonly known as the Brown Recluse. (derm.city)