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  • receptor
  • According to Japanese and Russian researchers' data, the patients suffering from larynx cancer and some other malignant growths, even before treatment starts experience increase of quantity of lymphocytes with T-cell receptor (TCR) genes mutations. (innovations-report.com)
  • Immunol
  • J.J. Woodruff, M. Katz, E. Lucas, and H.B. Stamber Jr, An in vitro model of lymphocyte homing.II.Membrane and cytoplasmic events involved in lymphocyte adherence to specialized high-endothelial venules of lymph nodes, J. Immunol. (springer.com)
  • D.M. Lewinsohn, R.F. Bargatze, and E.C. Butcher, Leukocyte-endothelial cell recognition: evidence of a common molecular mechanism shared by neutrophils, lymphocytes, and other leukocytes, J. Immunol. (springer.com)
  • thymus
  • Generally, a proportion of immature thymus-derived lymphocytes differentiate into mature CD4+ T-cells which produce a certain amount of cytokines, such as interleukin-2 (IL-2) and gamma interferon. (wikipedia.org)
  • B cells mature into B lymphocytes in the bursa equivalent, which in humans is the GALT, which is thought to be located in the Peyer's patches of the intestine, while T cells migrate to and mature in a distinct organ, called the thymus. (wikipedia.org)
  • 2001
  • S. J. McLeod and M. R. Gold, "Activation and function of the Rap1 GTPase in B lymphocytes," International Reviews of Immunology , vol. 20, no. 6, pp. 763-789, 2001. (hindawi.com)
  • protein
  • This protein came to be known as Lymphocyte T-Cell Immunomodulator (LTCI). (wikipedia.org)
  • Lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa), also known as LCP2 or SLP-76, is a gene that encodes a signal-transducing adaptor protein. (wikipedia.org)
  • leukocyte
  • Donor lymphocyte (or leukocyte) infusion (DLI) or buffy coat infusion is a form of adoptive immunotherapy used after hematopoietic stem cell transplantation. (wikipedia.org)
  • cells
  • The Encyclopaedia Britannica states that lymphocytes are primarily categorized into B lymphocytes and T lymphocytes, also called B cells and T cells. (reference.com)
  • Lymphocytes generally last for a short time, with an average life span ranging from a week to a few months, although some cells live for years and form a group of long-lived T and B cells, according to the Encyclopaedia Britannica. (reference.com)
  • Lymphocytes are produced by the same stem cells that produce red blood cells. (reference.com)
  • A person with a high lymph count could be suffering from a condition called lymphocytosis, an elevated level of white blood cells called lymphocytes. (reference.com)
  • Double increase of mutant lymphocyte frequency (more than 6.2 mutants per 10,000 cells) as compared to the background group was discovered with 37 percent of cancer patients, and this result cannot be considered accidental. (innovations-report.com)
  • T lymphocytes (T cells) are responsible for cell-mediated immunity. (howstuffworks.com)
  • Seventy-five percent of lymphocytes are T cells. (howstuffworks.com)
  • Lymphocytes, sometimes referred to as "fighter cells," attack infection-causing microorganisms. (ehow.co.uk)
  • Lymphocytes are white blood cells whose function is to fight off infection. (ehow.co.uk)
  • There are three major categories of lymphocytes: B-cells, T-cells and NK-cells. (ehow.co.uk)
  • lymphocytes, particularly T-cells, and have had trouble finding one. (bio.net)
  • Tumor-infiltrating lymphocytes, also tumour infiltrating lymphocytes, are white blood cells that have left the bloodstream and migrated into a tumor. (wikipedia.org)
  • The three major types of lymphocyte are T cells, B cells and natural killer (NK) cells. (wikipedia.org)
  • Stimulator cell populations that also contain T-cells (Two way mixed lymphocyte reaction) will replicate in the presence of the Responder cells, therefore for a One way mixed lymphocyte reaction, stimulator cells are prevented from replicating by irradiation or treatment with mitomycin C, a DNA crosslinker to prevent cell replication. (wikipedia.org)
  • The symptom of episodic angioedema in lymphocyte-variant hypereosinophilia resembles that occurring in Gleich's syndrome, a rare disease that is accompanied by secondary hypereosinophilia plus a sub-population of CD3(-), CD4(+) T cells and therefore proposed, at least in many patients, a subtype of lymphocyte-variant hypereosiophilia. (wikipedia.org)
  • Clinically, this is similar to severe combined immunodeficiency (SCID), in which lymphocyte precursor cells are improperly formed. (wikipedia.org)
  • As a notable contrast, however, bare lymphocyte syndrome does not result in decreased B- and T-cell counts, as the development of these cells is not impaired. (wikipedia.org)
  • Patients might require standard chemotherapy, to reduce the amount of cancer cells they have prior to their donor lymphocyte infusion. (wikipedia.org)
  • variant
  • Lymphocyte-variant hypereosinophila, also termed lymphocyte variant eosinophilia, is a rare disorder in which eosinophilia or hypereosinophilia (i.e. a large or extremely large increase in the number of eosinophils in the blood circulation) is caused by aberrant population of lymphocytes. (wikipedia.org)
  • Hence, lymphocyte-variant hypereosinophilia can be regarded as a precancerous disease. (wikipedia.org)
  • The typical patient with lymphocyte-variant hypereosinophilia presents with an extended history of hypereosinophilia and cutaneous allergy-like symptoms. (wikipedia.org)
  • Lymphocyte-variant hypereosinophilia usually takes a benign and indolent course. (wikipedia.org)
  • blood
  • however, adults with more than 3,000 lymphocytes per milliliter of blood are generally considered to suffer from lymphocytosis. (reference.com)
  • In some cases, children must have more than 9,000 lymphocytes per milliliter of blood to be considered to suffer from lymphocytosis. (reference.com)
  • What is the cause of having a high lymphocyte count in the blood? (reference.com)
  • Thus, European researchers have discovered that people with increased frequency of chromosomal abnormalities in lymphocytes of blood more often fall ill with cancer. (innovations-report.com)
  • The greater susceptibility to infection was shown to be directly attributable to a dramatic decrease in peripheral blood lymphocytes in thymectomized animals. (wikipedia.org)
  • Lymphocytes continually pass back and forth between lymph tissue, lymph fluid and blood. (howstuffworks.com)
  • Medical intervention may be necessary if the number of lymphocytes circulating in the blood becomes depressed. (ehow.co.uk)
  • Lymphocytopenia, the medical term for a low number of lymphocytes circulating in the blood, places individuals at a high risk for infection. (ehow.co.uk)
  • My daughter is about the same age and has chronic low lymphocytes results when her blood is drawn. (medhelp.org)
  • citation needed] Microscopically, in a Wright's stained peripheral blood smear, a normal lymphocyte has a large, dark-staining nucleus with little to no eosinophilic cytoplasm. (wikipedia.org)
  • In normal situations, the coarse, dense nucleus of a lymphocyte is approximately the size of a red blood cell (about 7 μm in diameter). (wikipedia.org)
  • Free lymphocytes constantly recirculate in blood after their re-entry from lymphoid tissue, via lymphatic and thoracic ducts. (wikipedia.org)
  • viral
  • A high lymphocyte count is referred to as lymphocytosis and is caused by a bacterial or viral infection, cancer, autoimmune disorders, tuberculosis, HIV/AI. (reference.com)
  • Reactive lymphocytes are usually associated with viral illnesses, but they can also be present as a result of drug reactions (such as phenytoin), immunizations, radiation, and hormonal causes (such as stress and Addison's disease), as well as some autoimmune disorders (such as rheumatoid arthritis). (wikipedia.org)
  • genes
  • The bare lymphocyte syndrome, type II (BLS II) is a rare recessive genetic condition in which a group of genes called major histocompatibility complex class II (MHC class II) are not expressed. (wikipedia.org)
  • interaction
  • E.C. Butcher, R.G. Scollay, and I.L. Weissman, Organ specificity of lymphocyte migration: Mediation by highly selective lymphocyte interaction with organ-specific determinants on high endothelial venules, Eur. (springer.com)
  • Homing
  • W.M. Gallatin, I.L. Weissman, and E.C. Butcher, A cell surface molecule involved in organ-specific homing of lymphocytes. (springer.com)
  • S. Jalkanen, R. Bargatze, L. Herron, and E.C. Butcher, A lymphoid cell surface glycoprotein involved in endothelial recognition and lymphocyte homing in man, Eur. (springer.com)
  • cell
  • Lymphocyte T-Cell Immunomodulator is a single chain polypeptide that is a strongly cationic glycoprotein and is purified with cation exchange resin. (wikipedia.org)
  • If the mutated cell divides significantly, the resulting clonal population may be eliminated by a T lymphocyte response. (wikipedia.org)
  • large
  • Therefore, a large number of mutant T-lymphocytes with a person means that their owner has become a prey to irradiation or his/her genome is non-stable for some reason. (innovations-report.com)