Lymphocyte surface molecule. Medical search. Frequent questions

These proteins are expressed on the surface of antigen-presenting cells and interact with ligands (e.g. (wikipedia.org)
Antigen stimulation of lymphocytes induces CD229 clustering to sites of T cell‑B cell contact (7). (rndsystems.com)
discuss the role of integrins in T cell- mediated immunity, with a focus on how these receptors participate in lymphocyte recirculation and T cell activation, how antigen stimulation regulates integrin activity, and how integrins define functionally unique subsets of T cells and APCs. (scielo.br)
crude female worm surface antigen (CFSWA). (who.int)
The antibody recognizes a unique molecule of the pathogen, called an antigen . (wikipedia.org)
14 As the strongest antigen presenting cell (APCs), DCs play an important role in the immunity of the ocular surface. (bmj.com)
Cytokine is a protein molecule released by a cell when activated by an antigen . (daviddarling.info)
Lifitegrast, 5%, preservative-free topical solution, a lymphocyte function-associated antigen 1 (LFA-1) antagonist administered twice daily, was approved by the FDA in 2016 for treatment of dry eye. (aao.org)
Murine MC are divided into three subsets based on surface expression of lymphocyte antigen 6 complex, locus C (Ly6C) ( 3 , 4 ). (frontiersin.org)
The protein intercellular adhesion molecule 3 (ICAM-3) functions as a receptor for LFA-1 (leukocyte function-associated antigen-1) and mediates adhesive interactions of leukocyte cell surface adhesion molecules in inflammatory and immune response. (sigmaaldrich.com)
Lifitegrast works by binding to the integrin lymphocyte function-associated antigen-1, blocking the cell surface protein's interaction with its ligand, intercellular adhesion molecule-1, which is excessive in the corneal and conjunctival tissues of dry eye patients. (pharmacytimes.com)
The implications of the immature surface antigen expression and the ability to form junctions are discussed and the position of thymocytes which can form junctions in intrathymic lymphocyte differentiation and development are explored. (gla.ac.uk)
2,3 Lifitegrast blocks the interaction of lymphocyte-associated antigen-1 and intercellular adhesion molecule (LFA-1 and ICAM-1), thereby reducing T-cell activation, proliferation and migration as well as cytokine release on the ocular surface. (crstoday.com)
The antibody is produced by a white blood cell called a B lymphocyte , based on the foreign antigen. (sciforums.com)
Although some antigens (Ags) can stimulate the immune response directly, T cell-dependent acquired immune responses typically require antigen-presenting cells (APCs) to present antigen-derived peptides within major histocompatibility complex (MHC) molecules. (msdmanuals.com)
Follicular dendritic cells are a distinct lineage (a different cell type than conventional dendritic cells), do not express class II MHC molecules, and therefore do not present antigen to Th cells. (msdmanuals.com)
T-lymphocytes recognise a foreign substance, an antigen, on the surface of foreign or infected cells. (lu.se)
When the T-lymphocyte and antigen connect, the T-cell releases substances that kill the cell. (lu.se)
On a virus-infected host cell, the antigen is made up of an MHC molecule and attendant virus protein. (lu.se)
Reprogramming restored the expression of antigen presentation complexes and costimulatory molecules on the surfaces of tumor cells, allowing the. (lu.se)
Human primary tumor cells could also be reprogrammed to increase their capability to present antigen and to activate patient-specific tumor-infiltrating lymphocytes. (lu.se)
The cellular response is mainly a lymphocyte-mediated reaction, whereas the humoral response includes production of antibodies against the antigen by the plasma cells. (medscape.com)
Immunoglobulins (Igs), the term is sometimes used interchangeably with "antibodies," are glycoprotein molecules produced by B lymphocytes and plasma cells in response to an immunogen or after recognition of specific epitopes on the antigen. (medscape.com)

DCs express lymphocyte costimulatory molecules that migrate to lymphoid organs and secrete cytokines to initiate immune responses. (bmj.com)

The area of Lymphocyte Development and Differentiation has been the target for several publications in previous volumes of this scientific series. (scielo.br)
1989) demonstrated that the lymphocyte homing receptor is identical to the human leukocyte surface glycoprotein called CDw44, on the basis of studies at the Third International Workshop on Human Leukocyte Differentiation Antigens. (wdv.com)
1989)' 'demonstrated' 'sameness' 'the human leukocyte surface glycoprotein' 'is called' 'CDw44' 'studies' 'were conducted at' 'the Third International Workshop on Human Leukocyte Differentiation Antigens. (wdv.com)
This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. (origene.com)
This study aims to explore molecule signaling mediating MC subset differentiation in HHcy and control mice. (frontiersin.org)
Finally, we established 3 groups of transcriptional models to describe Ly6C high to Ly6C low MC subset differentiation, immune checkpoint regulation, Ly6C high MC to MΦ subset differentiation and Ly6C low MC to lymphocyte functional adaptation. (frontiersin.org)
Subsequent differentiation allows for rear- analysis of a set of mouse B lineage cell lines rep- rangements of the Ig light-chain (IgL) genes that replace the resenting defined stages of B cell development us- surrogate light-chain genes on the surface of the B cell [8]. (lu.se)

About 40% of those receptor molecules bear endoglycosidase H sensitive glycans responsible of the lectin binding activity. (nih.gov)
1990) demonstrated that CD44 is the main cell surface receptor for hyaluronate. (wdv.com)
The mouse monoclonal antibody Hermes-3 recognizes the 85-95 kD human lymphocyte homing receptor. (wdv.com)
1989) refined the assignment of the lymphocyte homing receptor gene to 11pter-p13 by study of Chinese hamster-human cell hybrids in which the human parent cells had various deletions of human chromosome 11. (wdv.com)
the lymphocyte homing receptor' 'also appears to be identical'' to the Pgp-1 glycoprotein of Omary et al. (wdv.com)
OX40 is a potent co-stimulatory receptor on the surface of T lymphocytes. (bmj.com)
Ontogeny of lymphocyte homing receptor expression in the mouse thymus. (southernbiotech.com)
T-cell-receptor-independent activation of cytolytic activity of cytotoxic T lymphocytes mediated through CD44 and gp90 MEL-14 . (southernbiotech.com)
Ly6C high MC exhibited activated neutrophil degranulation, lysosome, cytokine production/receptor interaction and myeloid cell activation pathways, and Ly6C low MC presented features of lymphocyte immunity pathways in both mice. (frontiersin.org)
Other unusual features of the receptor include its ability to engage classes of molecules, rather than individual ligands, and its enhanced surface expression in environments rich in RAGE ligands. (jci.org)

Interleukins are a group of cytokines (secreted signaling molecules) that were first seen to be expressed by white blood cells ( leukocytes , hence the -leukin ) as a means of communication ( inter- ). (wikidoc.org)
T lymphocytes are conventionally divided into subsets based upon expression of co-receptors, cytokines and surface molecules. (nih.gov)
They have proinflammatory functions: they produce effector molecules (reactive oxygen and nitrogen intermediates) and inflammatory cytokines (IL-1 β , TNF α , and IL-6) and participate as inducer and effector cells in polarized Th1 responses. (hindawi.com)
Cytokines are involved in cell-to-cell communications, acting as enhancing mediators for immune responses (see immune system ) through interaction with specific cell-surface receptors on leukocytes . (daviddarling.info)
Kinds of cytokines include interleukins (produced by leukocytes), lymphokines (produced by lymphocytes), interferons , and tumor necrosis factor. (daviddarling.info)
The aim of our research was to determine how immunotherapy changes the proportion of lymphocyte subsets in dog peripheral blood and the levels of cytokines secreted by these cells during therapy. (mdpi.com)

It inhibits binding of intercellular adhesion molecule-1 (ICAM-1) to LFA-1 and has been effective in reducing ocular surface inflammation. (aao.org)
The gene ICAM3 (intercellular adhesion molecule 3) encodes type I membrane glycoprotein that belongs to the immunoglobulin (ig) superfamily. (sigmaaldrich.com)

The CAR-containing exosomes express a high level of cytotoxic molecules and inhibit tumour growth. (nature.com)
Cytotoxic T lymphocytes (CTL) bind to class I molecules, sample the peptides being presented, and lyse those cells that display unusual fragments derived from viruses or tumors. (the-scientist.com)
Overall, the study findings showed that dietary trans-vaccenic acid increases effector cytotoxic T lymphocyte activity and anti-tumor immunity in the in vivo settings. (innovationtoronto.com)
Intracellular antigens (eg, viruses) can be processed and presented to CD8 cytotoxic T cells by any nucleated cell because all nucleated cells express class I MHC molecules. (msdmanuals.com)

Molecules on the surface of lymphocytes called homing receptors interact specifically with HEV and play a central role in the migration. (wdv.com)
Initially, all antibodies are of the first form, attached to the surface of a B cell - these are then referred to as B-cell receptors (BCR). (wikipedia.org)
Galectin-1 and -3 were found to bind to glycosylated receptors at the surface of tumor-infiltrating lymphocytes (TIL), forming glycoprotein-galectin lattices that could reduce the motility and therefore the functionality of surface molecules. (raysahelian.com)
2003), and (c) availability of T lymphocytes way how skin sensitization is dealt with in toxicological with T-cell receptors specific for the hapten-peptide con- risk assessment: while older test systems aimed at pure jugates formed (Budinger et al. (cdc.gov)

The NK cells are sometimes labeled "large granular lymphocytes," while the T cells and B cells are labeled as "small lymphocytes. (newworldencyclopedia.org)
Effector B cells can begin secreting antibody while they are still small lymphocytes, but the end stage of their maturation pathway is a large plasma cell … which continuously secretes antibodies at the astonishing rate of about 2000 molecules per second. (sciforums.com)

Human peripheral blood mononuclear cell (PBMC) lymphocytes were stained with Mouse Anti-Human CD3e PE-conjugated Monoclonal Antibody (Catalog # FAB100P ) and either (A) Mouse Anti-Human CD8a Alexa Fluor® 647-conjugated Monoclonal Antibody (Catalog # FAB1509R) or (B) Mouse IgG 2B Alexa Fluor 647 Isotype Control (Catalog # IC0041R ). (rndsystems.com)
The monoclonal antibody MEL-14 blocks in vitro binding of lymphocytes to peripheral lymph node HEV and inhibits in vivo lymphocyte extravasation into peripheral lymph nodes and the late stages of leukocyte rolling. (southernbiotech.com)
Variable region constitutes the antibody binding region of the molecule to the different antigens as it consists of about 110 amino acids that vary widely among the different antibody molecules. (medscape.com)

The mice with enhanced immunity produced high levels of a hitherto unknown protein, which the researchers named lymphocyte expansion molecule, or LEM. (innovationtoronto.com)
Atacicept is a fusion protein that blocks B-lymphocyte stimulator and a proliferation-inducing ligand, which are increased in patients with SLE. (bmj.com)
This was accompanied by higher numbers of Ly6C hi monocytes in peripheral blood, as well as higher expression of monocyte chemoattractant protein-1 and adhesion molecules in the hearts of MI-operated Hmox1 −/− mice. (springer.com)
Antibodies can be found on the surface of lymphocytes as an integral part of the cell membrane protein or can be freely circulating in the blood or be part of one of the body's gland secretion. (medscape.com)

Secreted antibodies bind to antigens on the surfaces of invading microbes (such as viruses or bacteria), which flags them for destruction. (newworldencyclopedia.org)
Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. (thermofisher.com)
Thymocytes were fractionated using a range of monoclonal antibodies specific for a range of lymphocyte surface antigens using complement mediated cytotoxicity (CMC) and fluorescence activated cell sorting (FACS). (gla.ac.uk)
These experiments show that the thymocytes which can form junctions lack expression of Lyt-2 and la antigens, but express Lyt-1 molecules. (gla.ac.uk)
Extracellular antigens (eg, from many bacteria) that are phagocytosed or endocytosed can be processed into peptides and complexed with surface class II MHC molecules on professional APCs, which specialize in presenting antigens to CD4 helper T (Th) cells. (msdmanuals.com)
Antigens are the molecules that are recognized and stimulate the cells of immune system. (medscape.com)

HHcy in Cbs -/- mice reinforced inflammatory features in Ly6C high MC by upregulating inflammatory TFs ( Ets1 and Tbx21 ) and strengthened lymphocytes functional adaptation in Ly6C low MC by increased expression of CD3, DR3, ICOS, and Fos . (frontiersin.org)
HHcy reinforced inflammatory feature in Ly6C high MC and strengthened lymphocytes functional adaptation in Ly6C low MC. (frontiersin.org)
The autoimmune nature of diabetes and inflammatory cytokine IL-10 (as markers the major contribution of lymphocyte T- of inflammatory changes) and the soluble cells are well established. (who.int)

Leukocyte Typing II: Human B Lymphocytes. (bdbiosciences.com)
Zola H, Swart B, Nicholson I, Voss E. Leukocyte and Stromal Cell Molecules: The CD Markers. (bdbiosciences.com)
This member of the selectin family of cell adhesion molecules appears to be required for lymphocyte homing to peripheral lymph nodes and for leukocyte extravasation at sites of inflammation. (southernbiotech.com)
Leukocyte-endothelial cell recognition: evidence of a common molecular mechanism shared by neutrophils, lymphocytes, and other leukocytes. (southernbiotech.com)
A lymphocyte is a type of white blood cell (leukocyte) in the vertebrate immune system . (newworldencyclopedia.org)

Some EBOV infections generate a cytokine storm, which hinders peripheral natural killer cells (NK) and T and B lymphocytes. (cdc.gov)

CD44 is an integral cell membrane glycoprotein with a postulated role in matrix adhesion lymphocyte activation and lymph node homing. (wdv.com)

In order to determine the effect of ultraviolet radiation (UVR) on the cell adhesion molecules expressed in human dermal microvascular endothelial cells (HDMEC), the cells were exposed to varying UVR doses and the cell surface was examined for expression of intercellular cell adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1), and E-selectin. (elsevierpure.com)

The MHC genes are codominantly expressed, which means that each individual expresses these genes from both the alleles on the cell surface. (medscape.com)
Regulation of lymphocyte activation by the cell-surface molecule CD22. (bdbiosciences.com)
A cell-surface molecule involved in organ-specific homing of lymphocytes. (southernbiotech.com)
It has a molecular weight of 150 kDa and is expressed on the cell surface as a non-covalently linked homodimer. (beckman.com)
Human MC were initially divided into three subsets based on the cell surface expression of CD14 and CD16, and recently classified based on CD40 expression ( 2 - 5 ). (frontiersin.org)
However, following UVB exposure, ELISA demonstrated a significant increase in the baseline ICAM-1 cell surface expression on the HDMEC. (elsevierpure.com)
Donald F. Hunt (Departments of Chemistry and Pathology, University of Virginia, Charlottesville): "A complex mixture containing more than 10,000 peptide fragments derived from cellular proteins is displayed on the cell surface in association with molecules of the major histocompatibility complex (MHC), class I glycoproteins. (the-scientist.com)
Characterized by cell-surface molecules including CD103, CD69, and CD49a, T RM -like tumor-infiltrating lymphocytes (TILs) can be found in a wide range of human cancers, where they portend improved prognosis. (frontiersin.org)

Activation of B lymphocytes: integrating signals from CD19, CD22 and Fc γ RIIb1. (bdbiosciences.com)
The CD19 molecule is expressed on 100% of the peripheral B cells as defined by expression of kappa or lambda light chains. (thermofisher.com)
Human peripheral blood lymphocytes were stained with CD19 (clone SJ25C1) Brilliant Violet 650™ (filled histogram) or mouse IgG1, κ Brilliant Violet 650™ isotype control (open histogram). (biolegend.com)

The analysis was extended to immature lymphocytes of the thymus, and population of thymocytes was identified which was able to form junctions with murine fibroblasts, Swiss 3T3 and a BALB/c 3T3 and the hypoxanthine guanine phosphoribosyl transferase mutant (HGPRT-) subline of BHK/C13 baby hampster kidney fibroblast line TG2. (gla.ac.uk)

These cells include a subset of helper T lymphocytes, monocytes and macrophages. (cdc.gov)

In the mouse, CD62L is expressed on most thymocytes and on peripheral leukocytes, including B and T lymphocytes, neutrophils, monocytes, and eosinophils. (southernbiotech.com)
LFA-1 participates in several processes, such as T cell-mediated killing, T helper and B lymphocyte responses, natural killing, Ab-dependent cellular cytotoxicity by monocytes and granulocytes, and adherence of leukocytes to endothelial cells, fibroblasts, and epithelial cells. (sigmaaldrich.com)
We investigated the effects of monocyte-activating stimuli (IFN-gamma, IL-2, LPS, TNF-alpha, and GM-CSF) on the expression and function of CD38, starting from the observation that human monocytes and the derived lines U937, THP-1, and Mono-Mac-6 bear the molecule on their surface. (nih.gov)

Detection of CD8 alpha in Human PBMC lymphocytes by Flow Cytometry. (rndsystems.com)

Human CD38, a surface molecule expressed by immature and activated T and B lymphocytes, has been characterized as a molecule transducing activation and proliferation signals, and intervening in adhesion to endothelium via its ligand CD31. (nih.gov)
HIV preferentially infects and replicates in cells expressing the CD4 molecule, the ligand for viral attachment and subsequent cell entry (1). (cdc.gov)

Peripheral blood lymphocytes (PBL) were examined, to resolve the conflict in the literature as to the ability of PBL to form communicating junctions. (gla.ac.uk)

B lymphocytes, named after their site of origin in the bursa of Fabricius in birds or in the bone marrow in humans, form the basis for humoral immunity by their production of immunoglobulins. (medscape.com)
It plays a critical role in keeping the integrity of the ocular surface, serving as the source of the tear mucous layer 1 and assisting the immunity system. (bmj.com)
Deficiencies are highly variable with regard to symptoms, phenotype, genotype, severity, etc, because many cells and molecules are required for both natural and adaptive immunity . (lu.se)

Recent studies indicate that memory T lymphocytes contain distinct populations of central memory (T CM cells) and effector memory (T EM ) cells characterized by distinct homing capacity and effector function. (scielo.br)
Expression of CD62L on lymphocytes and neutrophils is rapidly down-regulated upon cell activation and the level of CD62L expression, along with other markers, distinguishes naive T cells from effector/memory T cells. (southernbiotech.com)

Ly6C high MC expressed higher levels of macrophage (MΦ) markers, whereas, Ly6C low MC highly expressed lymphocyte markers in both mice. (frontiersin.org)
To reduce the risk of analyzing cell line- pathway can be divided into distinct stages based on the specific features, we used several representative cell lines for recombination status of the Ig genes and on the expression each of four major stages in B cell development: pro-B, pre-B, pattern of surface markers and the presence of intracellular proteins [1- 6]. (lu.se)

In a very interesting review, P. MARRACK & J. KAPPLER focus on naïve, activated, and memory T cells survival separately, and discuss experiments done in vitro and in mice lacking or containing normal populations of lymphocytes. (scielo.br)
Using mouse-human T-lymphocyte hybrids and hybrids of Chinese hamster ovary cells with human amniotic fibroblasts, Ala-Kapee et al. (wdv.com)
Here, we report that CAR-T cells release extracellular vesicles, mostly in the form of exosomes that carry CAR on their surface. (nature.com)
By mRNA microarray analysis, T lymphocytes that express the C-type lectin CD161 were identified to share a transcriptional profile, which led to the identification of an innate function across these previously defined subsets, including CD8, CD4 and TCRgd T cells. (nih.gov)
It is absent from B and T lymphocytes as well as from red blood cells and platelets. (beckman.com)
This molecule is found on the surface of committed progenitor cells defined as the Granulocyte-Monocyte Colony Forming Units (CFU-GM) in normal bone marrow. (beckman.com)
Biopsies have demonstrated a measurable repopulation of goblet cells and a decrease in both conjunctival epithelial cell turnover and the number of lymphocytes. (aao.org)
The two main types of lymphocytes are T cells and B cells , which function in the adaptive immune system . (newworldencyclopedia.org)
Other lymphocyte-like cells are commonly known as natural killer cells, or NK cells, and are part of the innate immune system . (newworldencyclopedia.org)
While offering protection against millions of possible invaders, including viruses , bacteria , are cancer cells, lymphocytes allow normal body cells and helpful, symbiotic bacteria to flourish at the same time. (newworldencyclopedia.org)
A stained lymphocyte surrounded by red blood cells viewed using a light microscope. (newworldencyclopedia.org)
The two main categories of lymphocytes are the B lymphocytes ( B cells ) and T lymphocytes ( T cell ), both of which are involved in the adaptive immune system (Alberts 1989). (newworldencyclopedia.org)
In addition, lymphocyte-like cells called natural killer (NK) cells are involved in the immune system, albeit part of the innate immune system . (newworldencyclopedia.org)
NK cells distinguish infected cells and tumors from normal and uninfected cells by recognizing alterations in levels of a surface molecule called MHC (major histocompatibility complex) class I. NK cells are activated in response to proteins called interferons . (newworldencyclopedia.org)
Ly 1 in the mouse) is expressed on the majority of circulating T lymphocytes and a small population of B cells. (mssm.edu)
Overview of the Immune System The immune system distinguishes self from nonself and eliminates potentially harmful nonself molecules and cells from the body. (msdmanuals.com)
Lymphocytes, B and T cells, can respond selectively to thousands of non-self materials. (lu.se)
The immune system is an inherent self-defense system consisting of cells that helps the body distinguish between self and non-self molecules. (medscape.com)
These may be different molecules within the cells like proteins, polysaccharides, or nucleoproteins and may also be the whole cell, like a tumor cell or organisms like bacteria, viruses, fungi, parasites, or agents containing genetic material such as nucleic acids or lipids. (medscape.com)
B lymphocyte development is a highly ordered process pro- expression analysis without the use of intermediate amplifica- ceeding from the progenitor cells in the bone marrow (BM) to tion steps. (lu.se)

This investigation aims to provide a better understanding of the expression of OX40, PD-1, CTLA-4 and CD103 in OHNSCC tumor infiltrating lymphocytes (TIL). (bmj.com)

The Ig molecule is a polypeptide heterodimer that is composed of 2 identical light chains and 2 identical heavy chains connected by disulfide bonds (see the image below). (medscape.com)

Despite their efficiency, adoptive T-cell therapies show unique toxicities, which are distinct from those seen with conventional chemotherapies, monoclonal antibodies (mAbs), and small-molecule-targeted therapies. (nature.com)

ODE-conditioned mDCs maintained high expression of mCD14(+) and elevated phagocytosis while their DC features weakened as evidenced by decreased CD11c, CD83, HLA-DR, CD86, and CCR7 expression and reduced lymphocyte-stimulating capacity. (cdc.gov)
Control iDCs exposed to ODE during the final 2 days of iDC maturation (days 7 and 8) did not differ from control (no ODE) iDCs in surface marker expression and phagocytic ability, but exhibited enhanced lymphocyte-stimulating capacity. (cdc.gov)
Tissue expression and subcellular localization of the pro-survival molecule Bcl-w. (southernbiotech.com)
UVA irradiation did not affect the surface expression of ICAM-1, VCAM-1, or E-selectin on the HDMEC. (elsevierpure.com)
This study demonstrated that UVB irradiation can alter ICAM-1 and VCAM-1 expression on the HDMEC surface and that augmentation of ICAM-1 expression and the IL-1 α -dependent induction of VCAM-1 following UVB exposure might be important steps in the pathogenesis of sunburn. (elsevierpure.com)

There are up to five subpopulations of CD13 molecules possessing different levels of glycosylation, which may explain the different binding patterns of various CD13 antibodies. (beckman.com)

CD73-generated adenosine restricts lymphocyte migration into draining lymph nodes. (southernbiotech.com)

Lymphocytes play an important and integral role in the body's defenses, and are part of a system of extraordinary complexity and coordination. (newworldencyclopedia.org)

Experiments with soluble molecules having the N-terminal two domains of human ICAMs identified glycans of the high mannose type N-linked to the second domain of the dendritic cell-specific ICAM-grabbing nonintegrin lectin-ligands ICAM-2 and ICAM-3. (nih.gov)

An argument could be made that, by decreasing the friction of the eyelids' passage over the corneal and conjunctival epithelium, simple lubrication of the ocular surface may lessen inflammation, albeit slightly. (crstoday.com)

This adjunctive therapy helps to rapidly reduce ocular surface inflammation, but of course, topical corticosteroids cannot be used safely long term due to the risk of elevated IOP, the development of cataracts, and the potentiation of infection. (crstoday.com)

Ly6C low MC manifested activated T-cell signaling pathways and potentially can adapt the function of lymphocytes. (frontiersin.org)

A B lymphocyte surface molecule mediating activation and protection from apoptosis via calcium channels. (southernbiotech.com)
It may also function in lymphocyte activation, as well as in adhesion. (sigmaaldrich.com)

A scanning electron microscope (SEM) image of a single human lymphocyte. (newworldencyclopedia.org)
2014. A short treatment with galactomannan GM-CT-01 corrects the functions of freshly isolated human tumor-infiltrating lymphocytes. (raysahelian.com)

CD229 knockout mice show minimally impaired immune responses, suggesting functional redundancy with other molecules (11). (rndsystems.com)
ICAM-3 mediates the adhesion of resting T lymphocytes to LFA-1 and participates in the initiation of immune responses. (sigmaaldrich.com)
Generally these are secondary, tertiary and other subsequent immune responses to the same ahttps://en.wikipedia.org/wiki/Immunological_memory#:~:text=Immunological%20memory%20is%20the%20ability,responses%20to%20the%20same%20antigen.ntigen. (sciforums.com)
A particular PID can be caused by defects in any one of several molecules that are required for certain responses, because a defect in any of the sequential steps can impair the system. (lu.se)

Artificial tear preparations (demulcents and emollients) form an occlusive film over the corneal surface to lubricate and protect the eye from drying. (aao.org)

Anatomy47

Organisms15

Diseases5

Chemicals and Drugs110

Analytical, Diagnostic and Therapeutic Techniques and Equipment31

Phenomena and Processes50

Disciplines and Occupations1

Information Science3

Antigen23

Costimulatory molecules1

Differentiation7

Receptor10

Cytokines6

Intercellular adhesion2

Cytotoxic4

Receptors4

Small lymphocytes2

Antibody3

Protein4

Antigens6

Inflammatory3

Leukocyte5

Cytokine1

Glycoprotein1

Adhesion Molecule1

Cell Surface8

CD193

Thymus1

Macrophages1

Monocytes3

Flow Cytometry1

Ligand2

Peripheral blood1

Immunity3

Effector2

Markers2

Cells20

CD1031

Polypeptide1

Monoclonal antibodies1

Expression5

Antibodies1

Migration1

Body's1

Soluble1

Conjunctival1

Inflammation1

Pathways1

Activation2

Human2

Responses4

Corneal1