AnatomyOrganismsDiseasesChemicals and DrugsPhenomena and Processes
Brugia malayiFilarioideaFilariasisBrugiaLymphatic VesselsLymphatic SystemElephantiasis, FilarialOnchocercaDirofilaria immitisDipetalonemaMicrofilariaSetaria NematodeWuchereria bancroftiSetariasisParasitesBrugia pahangiDirofilariaLoiasisEndothelium, LymphaticHelminth ProteinsMansonellaFilaricidesWolbachiaOnchocerca volvulusAntigens, HelminthWuchereriaMansonelliasisDiethylcarbamazineDNA, HelminthLoaAntibodies, HelminthOnchocerciasisGerbillinaeLymphangiogenesisIvermectinAnthelminticsLarvaHost-Parasite Interactions
ElephantiasisNematodesEliminate Lymphatic FilariasisIdentified lymphatic filariasisBrugiaWuchereriaVesselsInfectionInfectionsMicrofilariaeMosquitoesLymphHuman filarialWormMalayiRisk of lymphatic filariasisCases of lymphatic filariasisBurden of lymphatic filariasisTreatment for lymphatic filariasisSuffering with lymphatic filariasisOnchocerciasis and lymphatic filariasisCirculating filarial antigenChronicAntigenIvermectinAlbendazoleDiseasesSpecies of filarialObstructionSymptoms of lymphaticHydroceleDiethylcarbamazineMosquito bitesHumansMalariaEliminationLymphedemaLymphoedemaPrevalenceMicrofilaremiaBloodstreamSystemAdult parasitesInfectiveAntifilarialMicrofilariaEndemic countriesOccurs
Elephantiasis19
  • The most spectacular symptom of lymphatic filariasis is elephantiasis - edema with thickening of the skin and underlying tissues-which was the first disease discovered to be transmitted by mosquito bites. (wikipedia.org)
  • Elephantiasis results when the parasites lodge in the lymphatic system. (wikipedia.org)
  • The disease is spread by mosquitoes infected with filarial worm parasites and can lead to severe, irreversible disfigurement (elephantiasis) and chronic pain. (cdc.gov)
  • Also known as elephantiasis, this NTD is caused by infection by filarial parasites transmitted through the bite of infected female mosquitoes. (kit.nl)
  • People with lymphedema and elephantiasis are not likely to benefit from DEC treatment because most people with lymphedema are not actively infected with the filarial parasite. (cdc.gov)
  • The presence of filarial parasites in the lymphatic system triggers inflammatory responses, causing damage and obstruction to the lymphatic vessels, leading to the characteristic symptoms of lymphatic filariasis such as lymphedema, hydrocele, and elephantiasis. (healthida.com)
  • Lymphatic filariasis, commonly known as elephantiasis, is a neglected tropical disease. (askdrmakkar.com)
  • When lymphatic filariasis develops into chronic conditions it leads to lymphoedema (tissue swelling) or elephantiasis (skin/tissue thickening) of limbs and hydrocele (scrotal swelling). (askdrmakkar.com)
  • Acute episodes of local inflammation involving skin, lymph nodes and lymphatic vessels often accompany chronic lymphoedema or elephantiasis. (askdrmakkar.com)
  • Lymphatic filariasis, which is also known as elephantiasis, is an infection that attacks the lymphatic system and causes painful, swollen limbs. (babydestination.com)
  • Filarial parasites can cause debilitating diseases such as lymphatic filariasis (elephantiasis) and onchocerciasis (river blindness), but they also modulate the immune system of their hosts to prevent the development of pathology and to enable their long-term survival within the host. (microbiology-bonn.de)
  • Onchocerciasis (river blindness) and lymphatic filariasis (elephantiasis) are neglected tropical diseases (NTDs) that cause severe disability and affect more than 106 million people, according to the latest reports from WHO. (biomedcentral.com)
  • Lymphatic filariasis (LF), commonly known as elephantiasis, is a painful and profoundly disfiguring disease. (who.int)
  • Elephantiasis Massive swelling of the legs also known as lymphatic FILARIASIS, It is caused by obstructed lymph vessels, which prevents drainage of lymph from the surrounding tissue. (hpathy.com)
  • The parasite worms Wuchereria bancrofti and Brugia malayi cause filariasis, which may lead to elephantiasis. (hpathy.com)
  • Elephantiasis is produced due to the disease Filariasis which is caused by parasites, which spread through mosquito bites to humans. (askdrshah.com)
  • Actually, Lymphatic Filariasis is called Elephantiasis, as it produces the above-stated symptoms. (askdrshah.com)
  • Elephantiasis is caused by filarial parasites and it happens over a long period of time due to the recurrence of infection. (askdrshah.com)
  • 2. The main complications of lymphatic fi lariasis are elephantiasis, lymphoedema and hydrocele. (who.int)
Nematodes9
  • Lymphatic filariasis is caused by 3 species of filarial nematodes, Wuchereria bancrofti , Brugia malayi , and B. timori . (cdc.gov)
  • Lymphatic filariasis is caused by infection with parasites classified as nematodes (roundworms) of the family Filariodidea. (askdrmakkar.com)
  • However, while hundreds of nematodes have been described in bats ( 2 ), their biology, life cycles and host-parasite specificity and interactions remain largely unknown ( 3 ). (frontiersin.org)
  • Onchocercid filarial nematodes, and especially the genera Litomosa and Litomosoides , occur relatively frequently in both Old World and Nearctic and Neotropical bats of the families Hipposideridae, Miniopteridae, Molossidae, Phyllostomidae, Pteropidae, Rhinolophidae and Vespertilionidae ( 4 - 13 ). (frontiersin.org)
  • Filarial nematodes are obligate parasites which have state-of-the-art lifecycles connected with people, other vertebrates, and you may arthropod vectors. (h2oprimemart.com)
  • The filarial nematodes that cause these diseases are transmitted by blood-feeding insects and produce chronic and long-term infection through suppression of host immunity. (ohoakebooks.com)
  • These two NTDs are caused by parasitic roundworms, the filarial nematodes Onchocerca volvulus (onchocerciasis), Wuchereria bancrofti , Brugia malayi , and Brugia timori (lymphatic filariasis). (biomedcentral.com)
  • Wolbachia are essential for multiple components of filarial nematode biology including larval growth and the production of offspring and, ultimately, survival of many filarial nematodes, including the causative parasites of onchocerciasis and lymphatic filariasis, making this symbiont a very attractive chemotherapeutic target for the treatment of both diseases. (biomedcentral.com)
  • Utilizing adults and microfilariae of the human lymphatic filarial parasite Brugia malayi, this project will investigate the biochemical pathways of arachidonic acid metabolism in these filarial nematodes. (grantome.com)
Eliminate Lymphatic Filariasis5
  • The ultimate goal of the WHO Global Pro- and low MF carriers could be a significant gramme to Eliminate Lymphatic Filariasis is reservoir of infection capable of sustaining to reduce blood microfilaraemia to levels at transmission [ 9 ]. (who.int)
  • The World Health Organization launched the global programme to eliminate lymphatic filariasis in 2000. (bmj.com)
  • Bancrof- of young children to assess changes in Eliminate Lymphatic Filariasis. (who.int)
  • To combat this disease, the WHO has launched a program aiming to eliminate lymphatic filariasis by the year 2020 in all the endemic countries using mass drug administration (MDA) to interrupt the disease's transmission. (eg.net)
  • Programme to Eliminate Lymphatic Filariasis for as long as the drugs would be required. (who.int)
Identified lymphatic filariasis1
  • The World Health Organization (WHO) has identified lymphatic filariasis as a major cause of disability worldwide, with an estimated 40 million individuals affected by the disfiguring features of the disease. (medscape.com)
Brugia8
Wuchereria7
Vessels13
Infection25
  • Before initiating DEC treatment for lymphatic filariasis, first rule out co-infection with Onchocerca volvulus in at-risk patients (see Sec. 5, Part 3, Ch. 17, Onchocerciasis / River Blindness ). (cdc.gov)
  • Chronic infection causes lymphatic dysfunction, resulting in progressive, irreversible swelling of the limbs and genitals ( box 1 ). (bmj.com)
  • Infection over long periods leads to damage of the lymphatic system, which can manifest as lymphoedema and hydrocele (scrotal swelling). (kit.nl)
  • Also known as kala-azar, this infection is caused by protozoan parasites, transmitted through the bite of infected sandflies. (kit.nl)
  • Men can develop hydrocele or swelling of the scrotum due to infection with one of the species of parasites that causes LF, specifically W. bancrofti . (cdc.gov)
  • Filarial infection can also cause tropical pulmonary eosinophilia syndrome. (cdc.gov)
  • This parasitic infection is caused by filarial parasites and transmitted through mosquito vectors. (healthida.com)
  • Several crucial indicators help assess the burden of lymphatic filariasis, such as the prevalence rate of infection, the number of microfilaria carriers, and the clinical manifestations of the disease. (healthida.com)
  • Infection occurs when filarial parasites are transmitted to humans through mosquitoes. (askdrmakkar.com)
  • Lymphatic filariasis infection involves asymptomatic, acute, and chronic conditions. (askdrmakkar.com)
  • The majority of infections are asymptomatic, showing no external signs of infection while contributing to transmission of the parasite. (askdrmakkar.com)
  • Most are the result of secondary bacterial skin infection where normal defences have been partially lost due to underlying lymphatic damage. (askdrmakkar.com)
  • Case report: Filarial infection of a parti-coloured bat: Litomosa sp. (frontiersin.org)
  • AAWZ1066S showed far superior efficacy (depletion of Wolbachia and sterilisation of microfilaria production) than the 'Gold-standard' anti- Wolbachia drug, doxycycline, at 7-day treatment regimens in two independent filarial infection animal models. (biomedcentral.com)
  • Lymphatic filariasis is a filarial worm infection that is a common cause of permanent disability worldwide. (msdmanuals.com)
  • We found evidence for Toll, IMD, and JAK-STAT pathway activity in response to early stages of B. malayi infection when the parasites are beginning to die in the resistant genotype. (cam.ac.uk)
  • Microfilaremia is a type of filarial infection that involves the presence of microfilariae, which are baby worms, in the blood. (healthelite.store)
  • In addition, antigen-driven T cell proliferation was measured to study the effect of the clinical status and / or infection status on the host responsiveness in lymphatic filariasis. (egyptianjournal.xyz)
  • This study re-emphasizes the importance of CAg measurements for accurately assessing the clinical status of filariasis and demonstrates that the presence or absence of active infection, not clinical status is most closely associated with the immune responsiveness in lymphatic filariasis. (egyptianjournal.xyz)
  • During the initial or prepatent period of tions critical to the success of lymphatic infection, large amount of soluble filariae occurs shortly after 3rdstage filarial antigens are excreted and infective larvae are deposited on the secreted by developing parasites, skin during blood feeding by the especially during the molting process. (egyptianjournal.xyz)
  • 1995) reported that the would provide an accurate indication of dynamics of acquisition of bancroftian active filarial infection (Mohsen et al. (egyptianjournal.xyz)
  • Ivecop DT 3mg is a parasite infection-killing remedy that you can take even as suffering from various parasitic infections within the intestinal tract, skin, and eyes. (medipills24.com)
  • Kalyanasundaram's research focuses on developing a vaccine against lymphatic filariasis, a tropical parasitic infection affecting over 120 million people in more than 40 countries. (uic.edu)
  • Even if Filariasis infection is controlled, the lymphatic swelling which has already occurred may not reverse. (askdrshah.com)
  • So the lymphatic swelling would not reduce significantly even after successful treatment of Filarial infection. (askdrshah.com)
Infections15
  • Lymphatic filariasis is caused by infections from parasites called filarial worms and leads to abnormal enlargements of body parts, which causes great pain. (borgenproject.org)
  • These asymptomatic infections still cause damage to the lymphatic system and the kidneys, and alter the body's immune system. (askdrmakkar.com)
  • Antimicrobial resistance (AMR) threatens the effective prevention and treatment of an ever-increasing range of infections caused by bacteria, parasites, viruses and fungi. (who.int)
  • AMR occurs when bacteria, viruses, fungi and parasites change over time and no longer respond to medicines making infections harder to treat and increasing the risk of disease spread, severe illness and death. (who.int)
  • Filarial infections have been understudied in bats. (frontiersin.org)
  • Eosinophils in filarial infections: Inducers of protection or pathology? (microbiology-bonn.de)
  • Discovery of Substituted Di(pyridin-2-yl)-1,2,4-thiadiazol-5-amines as Novel Macrofilaricidal Compounds for the Treatment of Human Filarial Infections. (microbiology-bonn.de)
  • Overview of Parasitic Infections A parasite is an organism that lives on or inside another organism (the host) and benefits (for example, by getting nutrients) from the host at the host's expense. (msdmanuals.com)
  • Filarial Worm Infections Overview Filarial worm infections are caused by certain roundworms and affect different parts of the body depending on the species of worm. (msdmanuals.com)
  • Successful labelling approaches will be piloted to track blood or lymphatic filarial infections using whole animal intravital bioimaging technology platforms (optical imaging and magnetic resonance imaging) in collaboration with MRC/UKRMP Centre for Preclinical Imaging, University of Liverpool. (growglobal.health)
  • Ivermectin is an anti-parasite medication that is used to treat various parasitic infections, including river blindness, threadworm infections, filarial worm infections (such as lymphatic filariasis or microfilaremia), hookworm infections, scabies, lice infestations, and helminthiasis (like roundworms, whipworms, and pinworms). (healthelite.store)
  • Ivermectin is effective against a variety of parasites and is used to treat infections such as river blindness, threadworm infections, filarial worm infections, hookworm infections, scabies, lice infestations, and helminthiasis. (healthelite.store)
  • It allows therapy of distinctive parasitic infections best inclusive of onchocerciasis, intestinal strongyloidiasis, filarial computer virus infections such as lymphatic filariasis and microfilaremia, scabies, pediculosis or head lice, helminthiasis like Ascariasis due to roundworms, Trichuriasis because of whipworm, and Enterobiasis because of Pinworm. (medipills24.com)
  • You can use the Vermact 6 mg Online to find a cure for various types of malicious parasites that cause infections in the eyes, intestines, and stomach. (hotmedz.com)
  • You can use the drug for curing onchocerciasis, intestinal strongyloidiasis, various filarial worm infections such as lymphatic filariasis, microfilaremia, hookworm infections, scabies, pediculosis known as head lice, and helminthiases such as Ascariasis and others. (hotmedz.com)
Microfilariae12
  • Individuals infected by filarial worms may be described as either "microfilaraemic" or "amicrofilaraemic", depending on whether microfilariae can be found in their peripheral blood. (wikipedia.org)
  • Blood - The microfilariae of all species that cause lymphatic filariasis and the microfilariae of Loa loa, Mansonella ozzardi, and Mansonella perstans are detected in blood. (medscape.com)
  • Urine - If lymphatic filariasis is suspected, urine should be examined macroscopically for chyluria and then concentrated to examine for microfilariae. (medscape.com)
  • Filarial antibody tests that detect elevated IgG and IgG4 can be useful, especially when microfilariae are not detected. (cdc.gov)
  • Serologic techniques provide an alternative to microscopic detection of microfilariae for the diagnosis of lymphatic filariasis. (cdc.gov)
  • These adult worms reside in the lymphatic system, where they produce millions of larvae known as microfilariae. (healthida.com)
  • A PCR assay targeting cytochrome c oxidase subunit 1 confirmed that adult worms from the peritoneal cavity and testicular microfilariae were of the same filarial species. (frontiersin.org)
  • While the standard filarial life cycle pattern involves a vertebrate definitive host and an invertebrate vector, represented by a blood-sucking ectoparasite, our finding suggests that microfilariae of this nematode species may also be semen-borne, with transmission intensity promoted by the polygynous mating system of vespertilionid bats in which an infected male mates with many females during the autumn swarming. (frontiersin.org)
  • Microfilariae were identified in one individual while circulating filarial antigens (CFAs) were detected in 10 individuals. (eg.net)
  • The ability of adults or microfilariae to incorporate 3H-arachidonic acid in vitro into parasite neutral and phospholipids has been assessed utilizing thin layer chromatography and reverse phase high performance liquid chromatography (HPLC). (grantome.com)
  • The adults produce millions of worm larvae (called microfilariae) that circulate in the bloodstream and lymphatic system. (msdmanuals.com)
  • The microfilariae that cause lymphatic filariasis circulate in the blood at night (called nocturnal periodicity). (pursuantmedia.com)
Mosquitoes5
  • When infected mosquitoes bite people, mature parasite larvae are deposited on the skin from where they can enter the body. (askdrmakkar.com)
  • Lymphatic filariasis is transmitted by different types of mosquitoes for example by the Culex mosquito, widespread across urban and semi-urban areas, Anopheles, mainly found in rural areas, and Aedes, mainly in endemic islands in the Pacific. (askdrmakkar.com)
  • These parasites are transmitted to humans through the bites of infected mosquitoes. (who.int)
  • We also found that resistant mosquitoes express anti-microbial peptides at the time of parasite-killing, and that this expression is suppressed in susceptible mosquitoes. (cam.ac.uk)
  • Dirofilaria immitis is a filarial parasite that is transmitted by mosquitoes, which serve as the intermediate host and vector. (pursuantmedia.com)
Lymph6
  • Most infected people are asymptomatic and will never develop clinical symptoms, despite the fact that the parasite damages the lymph system. (cdc.gov)
  • Their bites deposit a parasite that travels to the lymph system. (askdrmakkar.com)
  • Adult filarial worms reside in the lymphatics and lymph nodes and induce changes that result in dilatation of lymphatics and thickening of the lymphatic vessel walls. (arizona.edu)
  • Once the parasites enter the lymphatic system of the body, more symptoms appear due to their effect on lymph glands. (askdrshah.com)
  • Inflammation of lymphatic glands or lymph nodes may appear swelling and painful. (askdrshah.com)
  • Researchers have developed lab-generated lymph node-like organoids that, when transplanted into mice in place of lymph nodes that have been removed, drain fluid and connect to the animals' original lymphatic plumbing. (thelymphielife.com)
Human filarial3
  • citation needed] Human filarial nematode worms have complicated life cycles, which primarily consists of five stages. (wikipedia.org)
  • Mechanisms by which human filarial parasites cause disease and modulate the host's immune response are poorly understood. (grantome.com)
  • In the course of his research, Kalyanasundaram has shown that the vaccine is also effective against the parasite that causes heartworm disease in dogs, Dirofilaria immitis , which shares 80 percent genome similarity with the human filarial parasite. (uic.edu)
Worm9
  • The parasite causes the Guinea Worm Disease (GWD) in humans, transmitting when a person drinks water that is contaminated with water fleas containing Dracunculus medinensis larvae. (zmescience.com)
  • Further investigation will be necessary to better understand the bat-parasite interaction and the life cycle of this filarial worm. (frontiersin.org)
  • This disease is caused by the filarial worm. (healthaio.com)
  • It is basically a syndrome caused by nematode parasite called the filarial worm. (healthaio.com)
  • This parasite when enters into a human body it grows into an adult worm that lives in the lymphatic system of the human body. (healthaio.com)
  • The latest filarial worm, Onchocerca volvulus, grounds epidermis tumors and you will loss of sight which can be common among the anybody out of Africa as well as the Middle eastern countries. (h2oprimemart.com)
  • Lymphatic filariasis is transmitted when an infected mosquito bites a person and deposits larvae of the worm in the skin. (msdmanuals.com)
  • It is when the mosquito sucks blood containing eggs of filarial worm. (worced.com)
  • Dirofilaria immitis, also known as heartworm or dog heartworm, is a parasitic roundworm that is a type of filarial worm, a small thread-like worm, that causes dirofilariasis. (pursuantmedia.com)
Malayi2
  • There is a pressing need for new drugs against filarial parasites, such as B. malayi . (biomedcentral.com)
  • The findings revealed that the extract from the leaves of G. Sylvestre contains promising in vitro and in vivo antifilarial activity against human lymphatic filarial parasite B. malayi which may be further explored to new antifilarial agents. (biomedres.us)
Risk of lymphatic filariasis1
  • Sixty three per cent of the population at risk of lymphatic filariasis and 50% of the people infected worldwide live in South East Asia. (bmj.com)
Cases of lymphatic filariasis1
  • Mass administration is estimated to have cured or prevented up to 96 million new cases of lymphatic filariasis and averted more than $100bn of lifetime economic loss. (bmj.com)
Burden of lymphatic filariasis1
  • The highest burden of lymphatic filariasis occurs in countries in Africa, Asia, and the Pacific, with certain populations being more vulnerable due to poverty, inadequate sanitation, and limited access to healthcare. (healthida.com)
Treatment for lymphatic filariasis1
Suffering with lymphatic filariasis1
  • These acute attacks are debilitating, may last for weeks and are the primary cause of lost wages among people suffering with lymphatic filariasis. (askdrmakkar.com)
Onchocerciasis and lymphatic filariasis1
Circulating filarial antigen1
  • All consenting household members aged 2 years were surveyed and tested for circulating filarial antigen (CFA) using the rapid filarial test strip and for Wb123-specific antibodies using the Filaria Detect IgG4 ELISA. (cdc.gov)
Chronic4
  • The larvae then develop into adult worms in the lymphatic system, where they cause chronic inflammation and damage, leading to the clinical manifestations of lymphatic filariasis. (healthida.com)
  • These microscopic worms can infect the human lymphatic system, leading to the chronic and debilitating manifestations of the disease. (healthida.com)
  • Deep vein thrombosis must be differentiated from other causes of lower limb edema like chronic venous insufficiency , lymphatic filariasis , lipedema , myxedema , cellulitis and causes of generalized edema . (wikidoc.org)
  • Chronic lymphatic affection due to Filariasis over a period of time can lead to swelling of legs, scrotum (in males), vulva (females), or arms. (askdrshah.com)
Antigen1
  • Individuals positive for CAg had significantly lower lymphocyte proliferation responses to parasite antigen than did CAg-negative people. (egyptianjournal.xyz)
Ivermectin7
  • Ivermectin exerts its antiparasitic action by acting as a potent agonist at gamma-aminobutyric acid (GABA) receptors and potentiating the inhibitory signals sent to motor neurons, thus paralyzing the parasite. (medscape.com)
  • However, in some regions the co-endemicity of the filarial parasite Loa loa (loiasis) is an impediment due to the risk of severe adverse events (SAEs) associated with the drug ivermectin. (lancs.ac.uk)
  • The usual substance inside the pills, Ivermectin will prevent the increase of the malicious parasites and in flip, kill it to deliver a remedy to the affected person. (medipills24.com)
  • Usually, the substance Ivermectin will cause their paralysis, test their malicious and speedy increase to different frame parts and then interfere in the metabolism method of the disorder -causing parasite as well. (medipills24.com)
  • Vermact contains the ingredient Ivermectin which is a substance that acts as a killing agent of malicious parasites. (hotmedz.com)
  • F ollowing the passing of the resolution, two drug manufacturers donated albendazole and ivermectin to the lymphatic filariasis programme for as long as the drugs would be required. (who.int)
  • This article is a compilation of summaries prepared by lead investigators for large-scale safety and efficacy studies on mass drug administration of IDA (ivermectin, diethylcarbamazine, and albendazole) for lymphatic filariasis. (cdc.gov)
Albendazole3
Diseases7
  • Neglected tropical diseases are transmitted diseases caused by parasites, and are usually found in tropical and subtropical regions. (borgenproject.org)
  • Sometimes, parasites can have surprising benefits , and some of them are even good for the human body, protecting us from some diseases . (zmescience.com)
  • Malaria is caused by a parasite called plasmodium and one of the most common vector-borne diseases. (babydestination.com)
  • 2) Filarial immunomodulation and its beneficial impact on life-style diseases such as diet-induced insulin resistance in both the L. sigmodontis animal model as well as a human study with filariasis patients in Cameroon. (microbiology-bonn.de)
  • Lymphatic filariasis, a mosquito-borne disease, has been one of the most prevalent diseases in tropical and subtropical countries and is accompanied by a number of pathological conditions. (arizona.edu)
  • The objectives of the current presentation are to summarize the functional properties of HSPs and their role in innate and acquired immune responses, to throw light on their role in pathogenesis and parasites survival, to review the literature searching for new drug discovery and vaccine candidates for parasitic diseases, and finally to present their use in diagnosis and genotyping of some parasitic diseases. (eg.net)
  • An international consortium of scientists, the anti-Wolbachia consortium (A∙WOL), aimed to discover novel treatments for filarial diseases by targeting the parasite's endosymbiotic bacterium, Wolbachia. (biomedcentral.com)
Species of filarial1
  • There are many species of filarial worms, but only a few infect. (msdmanuals.com)
Obstruction1
Symptoms of lymphatic1
Hydrocele1
  • 4 Since 2000, the number of cases of filarial induced hydrocele has declined by about 49% to 19.4 million, and the number of cases of filarial induced lymphoedema by 23% to 16.7 million. (bmj.com)
Diethylcarbamazine4
  • Diethylcarbamazine (DEC) is the drug of choice for lymphatic filariasis, regardless of the causative parasite species. (cdc.gov)
  • Diethylcarbamazine (DEC) is commonly used in lymphatic filariasis and acts as both a microfilaricidal and macrofilaricidal agent. (medscape.com)
  • Possible actions of the antifilarial agent, diethylcarbamazine, on the pathways of parasite arachidonic acid metabolism will be determined. (grantome.com)
  • The main treatment for this type of disease is by using diethylcarbamazine or DEC. It kills the larvae of the parasite and eventually weakening the adult until it also dies. (worced.com)
Mosquito bites4
  • When a mosquito bites a person who has lymphatic filariasis, microscopic worms circulating in the person's blood enter and infect the mosquito. (cdc.gov)
  • Repeated mosquito bites over several months to years are needed to get lymphatic filariasis. (cdc.gov)
  • When the female Anopheles mosquito bites an infected person, the malaria parasite enters the mosquito's body and undergoes further development. (excellup.com)
  • These parasites spread by mosquito bites. (askdrshah.com)
Humans5
  • Eight known filarial worms have humans as a definitive host. (wikipedia.org)
  • Filariasis is a disease group caused by filariae that affects humans and animals (ie, nematode parasites of the family Filariidae). (medscape.com)
  • These notorious parasites cause a condition called schistosomiasis (also known as bilharzia) and to make things worse, there's not one but more than half a dozen species under the genus Schistosoma that see humans as their host. (zmescience.com)
  • This parasite lives in the large intestine of humans. (excellup.com)
  • The parasitic worms love to hang out in the human lymphatic system and blood channels , after being deposited inside humans by mosquitos. (iflscience.com)
Malaria2
  • Chimpanzees (Pan troglodytes) harbor rich assemblages of malaria parasites, including three species closely related to P. falciparum (sub-genus Laverania), the most malignant human malaria parasite. (bvsalud.org)
  • We used molecular assays to screen chimpanzee fecal samples, collected longitudinally and cross-sectionally from wild populations, for malaria parasite mitochondrial DNA. (bvsalud.org)
Elimination10
  • Once widespread in Africa and Asia, and swaths of Latin America and the Pacific, sustained elimination efforts based on mass drug administration have greatly reduced the global prevalence of parasites that cause lymphatic filariasis. (cdc.gov)
  • ABSTRACT The elimination strategy for lymphatic filariasis aims at reducing blood microfilaraemia to levels at which vector transmission cannot be sustained. (who.int)
  • Join us as we delve into the depths of lymphatic filariasis, shedding light on the strategies for control and elimination that hold the key to a brighter, healthier future. (healthida.com)
  • Understanding the epidemiology of lymphatic filariasis is crucial for effective control and elimination strategies. (healthida.com)
  • ABSTRACT The World Health Organization recommends that before lymphatic filariasis elimination in an area can be confirmed, an additional survey should be performed at least 5 years after stopping mass drug administration. (who.int)
  • Global programmes for control and elimination, such as APOC and OEPA for onchocerciasis and GPELF for lymphatic filariasis have been developed and made significant progress, but existing approaches principally target only the early larval stage of filarial worms known as microfilaria. (biomedcentral.com)
  • A surveillance system for lymphatic filariasis after its elimination in Sri Lanka Parasitology International 68 (2019) 73-78. (ac.lk)
  • World Health Assembly, in 1997, passed a resolu tion calling for the elimination of lymphatic filariasis as a global public health problem by 2020. (who.int)
  • The goal of the Programme for Elimination of Lymphatic Filariasis is the elimination of LF as a public health problem by the year 2020. (who.int)
  • BACKGROUND: Lymphatic filariasis (LF) has been targeted for global elimination as a public health problem since 1997. (cdc.gov)
Lymphedema1
  • T here's always something going on in the world of lymphedema and lymphatic research! (thelymphielife.com)
Lymphoedema1
  • Filarial induced lymphoedema is the second leading cause of disability in the world, accounting for about two million disability adjusted life years lost. (bmj.com)
Prevalence3
  • The epidemiology of lymphatic filariasis focuses on understanding the distribution and determinants of the disease, including its prevalence, incidence, and risk factors. (healthida.com)
  • All households surveyed in one village with the highest antibody prevalence were ICT negative, indicating an absence of lymphatic filariasis. (who.int)
  • Title : Prevalence and risk factors associated with lymphatic filariasis in American Samoa after mass drug administration Personal Author(s) : Coutts, Shaun P.;King, Jonathan D.;Pa'au, Molisamoa;Fuimaono, Saipale;Roth, Joseph;King, Mary Rose;Lammie, Patrick J.;Lau, Colleen L.;Graves, Patricia M. (cdc.gov)
Microfilaremia2
  • Patients with asymptomatic microfilaremia in lymphatic filariasis can be treated on an outpatient basis. (medscape.com)
  • Both lymphatic filariasis and microfilaremia can cause symptoms such as swelling in the limbs, fever, and tiredness. (healthelite.store)
Bloodstream2
  • A normal filarial lifecycle starts whenever human beings have the parasite out of the brand new bite away from an infected bloodstream-drawing bug. (h2oprimemart.com)
  • These parasites are released into the bloodstream of the host by the adult parasites. (pursuantmedia.com)
System3
Adult parasites1
  • Progressive lymphatic damage and pathology results from the summation of the effect of tissue alterations induced by both living and nonliving adult parasites. (arizona.edu)
Infective1
  • Infective filarial larvae grow into adult worms that inhabit the human lymphatic and subcutaneous tissues. (cdc.gov)
Antifilarial1
  • Further, by characterizing the biological activities of any filarial arachidonate derivatives, these studies may provide insights into novel mechanisms of parasite pathogenicity and may suggest rational approaches to the development of antifilarial agents. (grantome.com)
Microfilaria1
Endemic countries2
  • Lymphatic filariasis (LF) is a major vector-borne health problem affecting more than 120 million people in over 80 developing endemic countries. (eg.net)
  • In endemic countries, lymphatic filariasis has a major social and economic impact. (who.int)
Occurs1
  • Lymphatic filariasis occurs in 39 of the 46 Member States of the WHO African Region. (who.int)