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  • peritoneal
  • We reviewed and analyzed published data to determine the optimal treatment regimen for patients with peritoneal cytology-positive gastric adenocarcinomas. (springer.com)
  • Our search strategy consisted of combining the medical subject headings (MeSH) terms as well as using the standard PubMed syntax: "stomach neoplasm/" AND ("peritoneal lavage/" OR "positive peritoneal cytology.tw" OR "intraperitoneal free cancer cells.tw") NOT [(gastrointestinal stromal tum$).tw OR GIST.tw]. (springer.com)
  • Prostate
  • In addition, rVP1 can significantly suppress murine and human breast cancer metastasis and human prostate and ovarian cancer metastasis in vivo while F-HSA can significantly suppress murine breast cancer metastasis. (patentsencyclopedia.com)
  • Comprehensive immunohistochemical analysis of PD-L1 shows scarce expression in castration-resistant prostate cancer. (uzh.ch)
  • For example, while most patients with high-grade prostate cancers have increased levels of PSA, approximately 15 of these patients do not have an elevated PSA level. (78stepshealth.us)
  • To avoid these connotations for recently developed (against specific molecular or genetic targets) therapies which inhibit of growth-promoting signals coming from classic endocrine hormones (primarily estrogens for breast cancer and androgens for prostate cancer) is known as hormonal therapy , while the inhibition of other growth-promoting influences (especially those associated with receptor tyrosine kinases ) is known as targeted therapy . (wikipedia.org)
  • Oesophageal
  • This epidemic is fairly localised and is not evident in Asia, where squamous cell cancer remains the predominant oesophageal malignancy. (bmj.com)
  • They can only have confidence that the biopsy is from the oesophagus if an oesophageal gland duct is included. (bmj.com)
  • resection
  • left hemicolectomy with anterior rectal resection included division of inferior mesenteric artery at its origin after identification of the hypogastric nerve. (hindawi.com)
  • Lymphatic
  • Lymphatic metastasis plays an. (ebscohost.com)
  • Lymphatic mapping and sentinel lymph node biopsy (SLNB) are used to assess the presence of melanoma cells in the regional lymph nodes in order to help determine which patients may require regional lymph node dissections (LNDs) and systemic adjuvant therapy. (cancercarecenter.org)
  • Cancer is a term used for a disease in which abnormal cells in the human body start dividing and growing without control and are capable of invading other tissues through the blood and lymphatic system, a phenomenon known as metastasis. (mdpi.com)
  • The lymphatic vessels had been discovered in 1628, and scirrhus was now considered to be the product of an abnormal accumulation of lymph, which could later degenerate into cancer (29). (78stepshealth.us)
  • malignant
  • IMMUNOHISTOCHEMISTRY Introduction Metastasis is one of the fundamental biological characteristics of malignant tumours and is the leading cause of death in cancer patients. (healthdocbox.com)
  • Hypomethylation of DNA from benign and malignant human colon neoplasms. (springer.com)
  • However, non-specific expression in several benign and malignant diseases, false negative results in Lewis negative genotype and an increased false positive results in the presence of obstructive jaundice severely limit the universal applicability of serum CA 19-9 levels in pancreatic cancer management. (amegroups.com)
  • adjuvant
  • Adjuvant therapy is tailored based on the molecular profile of the neoplasm and can include aromatase inhibitors, anti-estrogen, anti-progesterone (or a combination of antiestrogen and antiprogesterone), and HER2 neu suppression therapy. (hindawi.com)
  • cardia
  • 6 The distinction of the oesophagus, hiatal hernia, and gastric cardia is often difficult. (bmj.com)
  • Standard teaching is that the gastric cardia is lined by columnar cardiac or junctional epithelium but pathologists are not uniform in their definitions. (bmj.com)
  • Proteins
  • Compositions of fibrillar proteins as anti-cancer metastasis therapeutics and methods of use thereof are provided herein. (patentsencyclopedia.com)
  • Proteins overexpressed in late stage cancers may not be overexpressed in earlier stages and, therefore, are not useful for early cancer detection. (78stepshealth.us)
  • The reciprocal problem of biomarkers indicating the presence of cancer when none is present (false positives) results because these proteins are not uniquely produced. (78stepshealth.us)
  • detect
  • The inability of these protein biomarkers to detect all cancers (false negatives) reflects both the progressive nature of cancer and its heterogeneity. (78stepshealth.us)
  • tumor growth
  • In the last years, several molecules able to target CXCR4 or CXCL12 have been developed to interfere with tumor growth, including pharmacological inhibitors, antagonists, and specific antibodies. (hindawi.com)
  • examination
  • Immunohistological examination revealed the presence of enterovirus in pancreatic islet cells and exocrine tissues and hyperexpression of pattern recognition receptors (PRRs) including melanoma differentiation-associated antigen 5 (MDA5), retinoic acid-inducible gene-I (RIG-I), Toll-like receptor (TLR)3 and TLR4, essential sensors of innate immunity, in islet cells and mononuclear cells (MNCs) infiltrating islets. (cancerindex.org)
  • tissue
  • Subgroup analyses (including by tissue origin, country and age), meta-regression were performed to determine the source of the heterogeneity. (biomedcentral.com)
  • pancreatic
  • The differential diagnosis with other pancreatic neoplasms is explored as well. (labome.org)
  • nevertheless few articles have comprehensively evaluated the evidence for its utility in pancreatic cancer management. (amegroups.com)
  • All English language articles pertaining to the role of CA 19-9 in pancreatic cancer were critically analyzed to determine its utility as a biomarker for pancreatic cancer. (amegroups.com)
  • CA 19-9 is the most extensively studied and validated serum biomarker for the diagnosis of pancreatic cancer in symptomatic patients. (amegroups.com)
  • Among recently diagnosed pancreatic cancer patients, 65-70% will have advanced disease (stage III-IV) at initial presentation. (amegroups.com)
  • intestinal
  • Akiyama Y, Maesawa C, Ogasawara S, Terashima M, Masuda T. Cell-type-specific repression of the maspin gene is disrupted frequently by demethylation at the promoter region in gastric intestinal metaplasia and cancer cells. (springer.com)
  • Diagnosis
  • Before we discuss protein computational tools and methods, we will give a brief background of current proteomic technologies used in cancer diagnosis. (78stepshealth.us)
  • For cancer diagnosis, both surface-enhanced laser desorption ionization (SELDI) and two-dimensional gel electrophoresis (2DE) approaches have been used.1,2 Recently protein-based microarrays have been developed that show great promise for analyzing the small amount of samples and yielding the maximum data on the cell's microenvironment.3-5 Isotope-coded affinity tags (ICAT)11 is a technology that facilitates quantitative pro-teomic analysis. (78stepshealth.us)