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  • Lutathera
  • FDA has approved lutetium Lu 177 dotatate (Lutathera, Advanced Accelerator Applications USA, Inc.) a radiolabeled somatostatin analog, for the treatment of somatostatin receptor-positive gastroenteropancreatic neuroendocrine tumors, including foregut, midgut, and hindgut neuroendocrine tumors in adults. (cancerletter.com)
  • The FDA has accepted a resubmitted new drug application (NDA) for Lutathera (lutetium [ 177 Lu] oxodotreotide) for the treatment of patients with gastroenteropancreatic neuroendocrine tumors (GEP-NETs). (cancercommons.org)
  • In the NETTER-1 Phase III Trial, a randomized prospective study, researchers focused on advanced midgut NETs and reviewed patient-reported quality of life questionnaires following treatment with lutetium-177 ( 177 Lu)-octreotate PRRT, also known as 177 Lu-DOTATATE-brand name Lutathera. (cancercommons.org)
  • patients
  • A German multicenter study, initiated by the German Society of Nuclear Medicine, demonstrates that lutetium-177 (Lu-177)-labeled PSMA-617 is a promising new therapeutic agent for radioligand therapy (RLT) of patients with metastatic castration-resistant prostate cancer (mCRPC). (cancercommons.org)
  • hafnium
  • Lutetium-hafnium ages that are based on the previously used λ 176 Lu of 1.93 × 10 −11 to 1.94 × 10 −11 year −1 are thus ∼4% too young, and the initial hafnium isotope compositions of some of Earth's oldest minerals and rocks become less radiogenic relative to bulk undifferentiated Earth when calculated using the new decay constant. (sciencemag.org)
  • europium
  • Synthesis and solution properties of lanthanum(III), europium(III), and lutetium(III) THP complexes and an x-ray diffraction study of a crystal containing four stereoisomers of a europium(III) THP complex (THP = 1,4,7,10-tetrakis(2-hydroxypropyl)-1,4,7,10-tetraazacyclododecane). (alfa.com)
  • PSMA
  • Charles Ryan and Carmel Pezaro have a conversation about Lutetium 177 PSMA based therapies in advanced prostate cancer. (urotoday.com)
  • We're talking today about nuclear medicine and lutetium and PSMA based therapies, where in Australia you've had a fair amount of experience. (urotoday.com)
  • Then this word came out, and I think initially from places in Germany and there were other areas, and then Australia became interested in medicalizing PSMA, particularly with lutetium. (urotoday.com)
  • Particular centers, Peter MacCallum, and centers in Sydney, have been working very hard in a research space looking at lutetium based PSMA. (urotoday.com)
  • Additionally, it is very true that because lutetium PSMA is not regulated in quite the same way, it actually can be given outside of clinical research. (urotoday.com)
  • One can pay to access lutetium PSMA and some men are choosing to do that. (urotoday.com)
  • Also, then a randomized trial being led through the ANZUP Clinical Trials Group, which is a randomized trial of lutetium PSMA or cabazitaxel chemotherapy. (urotoday.com)
  • With regards to the PSMA PET, before we get to the lutetium again, are you not getting bone scans on patients? (urotoday.com)
  • Lutetium-177-labelled PSMA-ligands (177Lu-PSMA) is a radionuclide therapy that is directed to PSMA expressing prostate cancer. (ovid.com)
  • A German multicenter study, initiated by the German Society of Nuclear Medicine, demonstrates that lutetium-177 (Lu-177)-labeled PSMA-617 is a promising new therapeutic agent for radioligand therapy (RLT) of patients with metastatic castration-resistant prostate cancer (mCRPC). (cancercommons.org)
  • meteorites
  • Lutetium-176 is a relatively abundant (2.5%) radioactive isotope with a half-life of about 38 billion years, used to determine the age of minerals and meteorites . (rug.nl)
  • earth's crust
  • Lutetium is not a particularly abundant element, although it is significantly more common than silver in the earth's crust. (rug.nl)
  • lanthanum
  • Lutetium is sometimes considered the first element of the 6th-period transition metals , although lanthanum is more often considered as such. (rug.nl)
  • Concentration
  • Determine the feasibility of measuring optical properties, tissue oxygenation, motexafin lutetium concentration, fluorescence, and blood flow by non-invasive means in these patients. (clinicaltrials.gov)
  • For each patient, the mean concentration of motexafin lutetium across tumor and normal samples will be summarized. (clinicaltrials.gov)
  • therapy
  • We, in the rest of the world, are seeing data coming out showing really interesting responses and some waterfall plots looking at some potential benefits of lutetium based therapy. (urotoday.com)
  • occurs
  • Lutetium usually occurs in association with the element yttrium [ citation needed ] and is sometimes used in metal alloys and as a catalyst in various chemical reactions. (rug.nl)
  • trace
  • Though lutetium composes only trace mounts (less than 0.1 percent by weight) of the commercially important minerals bastnasite and monazite , it has proved feasible to extract the metal as a by-product. (britannica.com)