AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsHumanitiesInformation ScienceNamed GroupsHealth CareGeographicals
Heart TransplantationTransplantation, HomologousHeartLiver TransplantationGraft RejectionHeart-Assist DevicesLungKidney TransplantationHeart FailureLung TransplantationBone Marrow TransplantationTissue DonorsHematopoietic Stem Cell TransplantationTransplantation, HeterotopicGraft SurvivalHeart RateTransplantation, AutologousCardiomyopathy, DilatedWaiting ListsImmunosuppressive AgentsTreatment OutcomeStem Cell TransplantationTissue and Organ ProcurementTime FactorsPostoperative ComplicationsOrgan TransplantationHeart DiseasesRetrospective StudiesFollow-Up StudiesTransplantation ConditioningTransplantationHeart Defects, CongenitalLung DiseasesHeart-Lung TransplantationTransplantation ImmunologyImmunosuppressionCardiomyopathiesPancreas TransplantationSurvival RateIslets of Langerhans TransplantationPostoperative PeriodLung NeoplasmsCyclosporineMyocardiumHeart, ArtificialCell TransplantationTransplantation, IsogeneicCardiomyopathy, RestrictiveSurvival AnalysisTransplantation ChimeraDonor SelectionRisk FactorsHemodynamicsProspective StudiesTransplantation ToleranceOrgan PreservationPrognosisHistocompatibility TestingGraft vs Host DiseaseRats, Inbred LewLung InjuryLiving DonorsVenae CavaePatient SelectionAssisted CirculationCord Blood Stem Cell TransplantationExtracorporeal Membrane OxygenationBiopsyPrimary Graft DysfunctionEndocardiumPostoperative CareBlood Grouping and CrossmatchingHistocompatibilityKaplan-Meier EstimateCarcinoma, Non-Small-Cell LungTacrolimusEchocardiographyHeart AtriaRecurrenceVentricular Function, LeftHeart Function TestsAcute DiseaseAnastomosis, SurgicalPeripheral Blood Stem Cell TransplantationChronic DiseaseHLA AntigensMyocarditisBrain DeathLiver FailureSinus Arrest, CardiacCardiovascular Surgical ProceduresFetal Tissue TransplantationCardiomyoplastyAllograftsInfectionPredictive Value of TestsMice, Inbred C57BLVentricular Dysfunction, LeftProtein-Losing EnteropathiesSkin Transplantation
Living-donorRecipientsCystic FibrosisPulmonaryExtracorporeal membrane ox2022TransplantsComplicationsAdvanced Lung DiseaseJournal of Heart and Lung TransplantationField of lung transplantationISHLTOrgansOutcomesDiseasePediatricMortalityCorneal TransplantationDetection of allograft dysfunction2016LiverKidneyRejectionDysfunctionBone MarrowCardiac surgeryDisordersSurgeryRenalUndergoIschemia-reperfusion injury2019ClinicalProceduresSurgicalBilateralDiseasesIndicationsBronchoscopyUnderwentSingle Lung TransplantDonorsComputed tomographyRecipientSevereDeveloped to transplantCongenital heartOrgan and tissueSurvival ratesTissue
Living-donor3
Recipients21
  • This article is meant not only to serve as an overview of the field of lung transplantation but also to highlight the unique challenges faced by pediatric lung transplant recipients, their families, and their healthcare teams. (medscape.com)
  • Outcomes after heart and lung transplants have improved, and many recipients survive long enough to develop secondary renal failure, yet remain healthy enough to undergo kidney transplantation. (johnshopkins.edu)
  • Furthermore, renal transplantation reduced the risk of death compared with dialysis by 43% for KAH and 54% for KAL recipients. (johnshopkins.edu)
  • With greater experience and analysis of significant numbers of cases, lung transplant recipients are living longer, and follow-up regimens are becoming streamlined. (medscape.com)
  • Thus, a comprehensive understanding of lung transplantation-related pathology is necessary for both tertiary care pathologists dealing with highly specialized lung transplantation teams and a much larger spectrum of healthcare providers who may be involved in the care of lung transplant recipients or candidates for lung transplantation. (medscape.com)
  • Many lung transplant physicians advocate surveillance bronchoscopy with transbronchial lung biopsy and bronchoalveolar lavage (TBB/BAL) to monitor lung recipients despite limited evidence this strategy improves outcomes. (nih.gov)
  • This report compares rates of infection (INF), acute rejection (AR), bronchiolitis obliterans syndrome (BOS) and survival in lung allograft recipients managed with surveillance TBB/BAL (SB) versus those with clinically indicated TBB/BAL (CIB). (nih.gov)
  • With no obvious advantage identified, surveillance bronchoscopy may pose a risk to stable lung transplant recipients. (nih.gov)
  • From the total sample, 37% of liver recipients and 20% of lung had cognitive disorders compared to only 9% of heart recipients. (hippokratia.gr)
  • Unfortunately, early operations resulted in problems such as infection and rejection, and heart recipients did not survive very long. (physio-pedia.com)
  • The airways of CF are susceptible to colonization by respiratory pathogens ( 3 ), a condition that is improved in lung transplant recipients. (cdc.gov)
  • Nevertheless, I. limosus infection has been reported twice in lung transplant recipients ( 4 , 5 ). (cdc.gov)
  • Infection rates among lung transplant recipients appear to be higher than those encountered in other solid organ transplant populations, likely related to the unique exposure of the lung allograft to the external environment and to the greater magnitude of immunosuppression employed 1 , 2 . (ersjournals.com)
  • We prospectively measured anti-HLA IgE antibodies in a cohort of kidney (n=60), liver , heart and lung (n=15 each) transplant recipients before and within one-year after transplantation , employing a single- antigen bead assay for HLA class I and class II antigens . (bvsalud.org)
  • Pre-existing anti-HLA IgE antibodies were detected in 10% of renal recipients (including 3.3% IgE -DSA) and in 4.4% of non-renal solid organ transplant recipients ( heart , liver and lung cohort). (bvsalud.org)
  • These data demonstrate that anti-HLA IgE antibodies occur at low frequency in kidney , liver , heart and lung transplant recipients . (bvsalud.org)
  • Today, a main focus of the transplant community is the long-term outcomes of lung and heart allograft recipients. (terasaki.org)
  • To investigate possible changes following lung transplantation, the structure and in vitro ciliary beat frequency (CBF) of airway epithelium from the cytology brushings of 9 heart-lung (HLT) and 5 single-lung (SLT) transplant recipients were examined. (soton.ac.uk)
  • Organ Transplantation.2 These Guiding Principles - whose emphases include voluntary donation, noncommercialization, genetic relation of recipients to donors and a preference for cadavers over living donors as sources - have considerably influenced professional codes, national, state and provincial legislation, and the policies of intergovernmental organizations. (who.int)
  • Unfavorable Outcome of Heart Transplantation in Recipients With Type D Personality. (bvsalud.org)
  • Although previous recommendations for preventing transmission of human immunodeficiency virus (HIV) through transplantation of human tissue and organs have markedly reduced the risk for this type of transmission, a case of HIV transmission from a screened, antibody-negative donor to several recipients raised questions about the need for additional federal oversight of transplantation of organs and tissues. (cdc.gov)
Cystic Fibrosis4
  • A 45-year-old woman in France who had received a lung transplant in 2016 for end-stage cystic fibrosis (CF) sought care for rhinorrhea on March 1, 2022. (cdc.gov)
  • Transplantation of patients with underlying cystic fibrosis (CF), whose native airways and sinuses are chronically infected with virulent bacterial pathogens, initially raised unique concerns about the potential excessive risk of postoperative infections. (ersjournals.com)
  • Developing a Decision Aid to Facilitate Informed Decision Making About Invasive Mechanical Ventilation and Lung Transplantation Among Adults With Cystic Fibrosis: Usability Testing. (cdc.gov)
  • Lung transplant referral for individuals with cystic fibrosis: Cystic Fibrosis Foundation consensus guidelines. (cdc.gov)
Pulmonary15
  • Role of pulmonary function in the detection of allograft dysfunction after heart-lung transplantation. (bmj.com)
  • 1 Program for Advanced Lung Disease and Lung Transplantation, Pulmonary and Critical Care Division, Department of Medicine, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA. (nih.gov)
  • CPT 33944 describes the standard backbench preparation of a cadaver donor heart allograft before transplantation, including the dissection of the allograft from surrounding soft tissues to prepare the aorta, superior vena cava, inferior vena cava, pulmonary artery, and left atrium for implantation. (codingahead.com)
  • Pulmonary Hypertension Pulmonary hypertension is a condition in which blood pressure in the arteries of the lungs (the pulmonary arteries) is abnormally high. (msdmanuals.com)
  • Although rare, pulmonary embolism, infections, or neoplasms in the allograft may be diagnosed in this manner, which would affect the decision to use the donor lung. (medscape.com)
  • A heart-lung transplant is performed for unsalvagable dual cardiac and pulmonary failure. (physio-pedia.com)
  • The most common underlying conditions requiring heart-lung transplants are congenital cardiac diseases with Eisenmenger syndrome and certain pulmonary hypertension disorders [1] . (physio-pedia.com)
  • pulmonary hypertension - where high blood pressure develops inside the blood vessels of the lungs, which can damage both the lungs and the heart. (physio-pedia.com)
  • In 1 case, a 22 year-old woman had pulmonary infiltrates develop within a month after lung transplantation ( 4 ). (cdc.gov)
  • He is the Associate Medical Director for Lung and Heart/Lung Transplantation at Stanford and director of the Pulmonary Fibrosis Foundation Care Center at Stanford. (stanford.edu)
  • to monitor response to treatments and pulmonary rehabilitation, and to predict the risk of disability or death in people with heart and lung disorders. (merckmanuals.com)
  • Pulmonary Rehabilitation Pulmonary rehabilitation is the use of supervised exercise, education, support, and behavioral intervention to improve how people with chronic lung disease function in daily life and to enhance. (merckmanuals.com)
  • Pulmonary rehabilitation is a program designed for people who have chronic lung disease. (merckmanuals.com)
  • Pulmonary rehabilitation programs may be used before a person's lung disease becomes severe. (merckmanuals.com)
  • This radiograph reveals an enlarged right heart and pulmonary artery dilatation in a 24-year-old woman with an unrestricted patent ductus arteriosus (PDA) and Eisenmenger syndrome. (medscape.com)
Extracorporeal membrane ox1
20221
Transplants11
  • From 1986 through June 2016, 2330 lung and 730 heart-lung transplants in children were reported to the Registry for the International Society for Heart and Lung Transplantation (ISHLT). (medscape.com)
  • Following a steady increase in pediatric lung transplants in the first decade of this millennium, with 125 reported to the ISHLT registry in 2009, numbers have remained stable with a range of 90 to 137 observed during the past 12 years. (medscape.com)
  • Although one-year survival rates have improved, long-term outcomes for children receiving lung transplants have not (see the image below). (medscape.com)
  • According to the International Society of Heart and Lung Transplantation (ISHLT) Registry, 2,330 pediatric lung and 730 pediatric heart-lung transplants have been performed through June 30, 2016. (medscape.com)
  • Lung transplants are used for people who are likely to die from lung disease within 1 to 2 years. (medlineplus.gov)
  • We used national data reported to United Network for Organ Sharing (UNOS) to evaluate outcomes of 568 kidney after heart (KAH) and 210 kidney after lung (KAL) transplants performed between 1995 and 2008. (johnshopkins.edu)
  • Given that sicker/riskier patients are now receiving more heart and lung transplants, future studies need to take place to better understand these patients so that they can have the same survival as patients entering transplant with less severe illnesses. (terasaki.org)
  • Sometimes it may be necessary to do multi-organ transplants since the liver or kidneys may be affected by a diseased heart. (manipalhospitals.com)
  • Heart-liver, heart-lung, and heart-kidney transplants are performed when replacing the heart alone may not be enough to save the patient. (manipalhospitals.com)
  • The number of human tissue transplants is increasing in both developed and developing countries, but global data on this form of transplantation are less complete. (who.int)
  • Access to transplantation is limited in low- and many medium-income countries, where the rate of transplants remains far below that of richer nations. (who.int)
Complications6
  • The indications for transplantation, the pharmacokinetics of immunosuppressants, and the complications of transplantation can be strikingly different for children compared with their adult counterparts. (medscape.com)
  • Complications of lung transplantation include rejection of the transplanted lung and infection. (medlineplus.gov)
  • Lung transplantation-related pathology encompasses a spectrum of disorders that include, but are not limited to, indications for lung transplantation (seen in explanted lungs), surgical complications (airway anastomotic and vascular complications), ischemia-reperfusion injury, rejection (acute and chronic), infections, and posttransplantation lymphoproliferative disorders (PTLDs). (medscape.com)
  • This article will review the major medical complications, excluding allograft rejection, which may be encountered in the lung transplant recipient. (ersjournals.com)
  • While offering a vital therapeutic option for patients with advanced lung disease, LTx remains fraught with complications that threaten both the quality and duration of the recipient's life. (ersjournals.com)
  • In addition toallograft rejection (a topic covered elsewhere in this series), a multitude of medical complications mark the post-transplantation course. (ersjournals.com)
Advanced Lung Disease2
  • A Society that Includes Basic Science, the Failing Heart and Advanced Lung Disease. (ishlt.org)
  • He performs health services and outcomes research focused on understanding and improving the lives and care of patients with advanced lung disease and is actively involved in clinical trials to improve outcomes in interstitial lung disease. (stanford.edu)
Journal of Heart and Lung Transplantation2
Field of lung transplantation2
  • However, the phrase "children are not just small adults" is nowhere more true than in the field of lung transplantation. (medscape.com)
  • Surgical advances, in conjunction with more effective immunosuppressive strategies, have propelled the field of lung transplantation forward and have made intermediate-term survival an achievable goal. (ersjournals.com)
ISHLT3
Organs14
  • Overview of Transplantation Transplantation is the removal of living, functioning cells, tissues, or organs from the body and then their transfer back into the same body or into a different body. (msdmanuals.com)
  • If the damage is severe in both organs, replacing the heart or lungs alone may not be possible. (physio-pedia.com)
  • Replacement with a healthy lung can promote the recovery of the diaphragm to its anatomical morphology, reinforcing the close relationship between these two organs. (frontiersin.org)
  • We mainly use organs donated by adults for children's organ transplantations. (hus.fi)
  • The test assesses the person's overall function but, if the person's exercise capacity is reduced, does not tell which of the individual organs and systems (that is, the heart, lungs, muscles and bones, or other organs and systems) is the limiting factor. (merckmanuals.com)
  • Transplantation of human organs and tissues1 saves many lives and restores essential functions in circumstances when no medical alternative of comparable effectiveness exists. (who.int)
  • The transplantation of solid organs, such as kidney, liver, heart or lung, is increasingly a regular component of health care in all countries, and is no longer a feature of health care in high-income countries alone. (who.int)
  • Nonetheless, the transplantation of organs and tissues does raise ethical concerns. (who.int)
  • The persistent and widening gap between patients' need for organs and the number available for transplantation has become a major concern to many Member States. (who.int)
  • Successful transplantation of organs and living tissues depends on continued medical follow-up and the patient's compliance with a regimen of immunosuppressive drugs. (who.int)
  • 5 United Nations General Assembly - Resolution A/RES/71/322 on Strengthening and promoting effective measures and international cooperation on organ donation and transplantation to prevent and combat trafficking in persons for the purpose of organ removal and trafficking in human organs, September 2017. (who.int)
  • A working group formed by the Public Health Service (PHS) in 1991 to address these issues concluded that further recommendations should be made to reduce the already low risk of HIV transmission by transplantation of organs and tissues. (cdc.gov)
  • This occurrence raised questions about the need for additional federal oversight of transplantation of organs and tissues. (cdc.gov)
  • The working group concluded that, although existing recommendations are largely sufficient, revisions should be made to reduce the already low risk of HIV transmission via transplantation of organs and tissues. (cdc.gov)
Outcomes1
  • His clinical research has primarily been directed toward surgical issues in complex congenital heart care and cardiac transplantation (focusing on advances with operative techniques, outcomes research and transplantation for congenital heart disease), with a particular emphasis on the development of mechanical ventricular assist devices for children, as well as stem-cell based valved conduits for pediatric application. (chop.edu)
Disease17
  • Lung transplantation has matured into an accepted therapeutic alternative for children with end-stage lung disease. (medscape.com)
  • That is, patients trade their end-stage lung disease for transplant lung disease, with the hope that it can be better managed. (medscape.com)
  • The cut surface shows the characteristic findings of the disease for which lung transplantation was indicated. (medscape.com)
  • At the Johns Hopkins Heart and Vascular Institute, cardiac specialists swiftly translate laboratory discoveries into new treatments, with the ultimate goal of saving more lives from heart disease, the leading cause of death in the United States. (hopkinsmedicine.org)
  • Joshua Mooney, MD, MS, is a board certified pulmonologist and critical care physician who specializes in the care of interstitial lung disease and lung transplant patients. (stanford.edu)
  • The influence of lung disease on the diaphragm has been poorly studied. (frontiersin.org)
  • Lung transplantation (LTx), by replacing a diseased lung with a healthy one, is an interesting model to evaluate the evolution of the diaphragmatic morphology before and after transplantation in the context of lung disease. (frontiersin.org)
  • Stress Testing Stressing the heart (by exercise or by use of stimulant drugs to make the heart beat faster and more forcibly) can help identify coronary artery disease. (merckmanuals.com)
  • Call 310-825-9011 to learn more about adult congenital heart disease treatment. (uclahealth.org)
  • The Ahmanson/UCLA Adult Congenital Heart Disease Center is the first and one of the largest facilities of its kind in the United States. (uclahealth.org)
  • The center is a tertiary care national and international resource that provides services to the growing number of patients with congenital heart disease who reach adulthood. (uclahealth.org)
  • We are pleased to announce the creation of the Adolescent/Young Adult Transitional Care Program, for Congenital Heart Disease . (uclahealth.org)
  • The program is the combined efforts of the Division of Pediatric Cardiology and the Ahmanson/UCLA Adult Congenital Heart Disease Center. (uclahealth.org)
  • The program provides comprehensive treatment of adolescents with congenital heart disease, ages 15 to 20. (uclahealth.org)
  • Patients who are new to the Ahmanson/UCLA Adult Congenital Heart Disease Center should ideally have their doctor's mail or fax in cardiac related medical records prior to scheduling an appointment. (uclahealth.org)
  • Tomasulo CE, Chen JM, Smith CL, Maeda K, Rome JJ, Dori Y. Lymphatic disorders and management in patients with congenital heart disease. (chop.edu)
  • For example, in developing and developed countries alike, kidney transplantation not only yields survival rates and quality-of-life that are far superior to those obtained with other treatments for end-stage renal disease, such as haemodialysis, but is also less costly in the long run. (who.int)
Pediatric4
  • Pediatric lung transplantation actuarial survival by era. (medscape.com)
  • Transfer patients with severe acute HF to a center with pediatric HF specialists and the expertise and ability to optimize medical therapy, evaluate for heart transplant, and if necessary, provide mechanical support. (medscape.com)
  • From 2008-2013, he served as Chief of Pediatric Cardiovascular Services and the David Wallace-Starr Foundation Professor at Weill Medical College of Cornell University, as well as Surgical Director of the Pediatric Heart Transplant Program at the Columbia University campus. (chop.edu)
  • Dr. Chen served as the Chief of Congenital Cardiac Surgery, Co-Director of the Heart Center, Professor of Surgery at the University of Washington School of Medicine, and holder of the Sam and Althea Stroum Endowed Chair in Pediatric Cardiovascular Surgery. (chop.edu)
Mortality3
  • Patients awaiting lung transplantation face high wait-list mortality, as injury precludes the use of most donor lungs. (nature.com)
  • Infection is an ever-present threat to the well-being of the lung transplant recipient and is a leading cause of both early and late mortality. (ersjournals.com)
  • The study will compare the time to a composite endpoint of relative decline in lung function [10% relative decline in forced vital capacity (FVC), first respiratory hospitalization, lung transplantation, or all-cause mortality] The secondary objectives will be to examine the effect of NAC on the components of the primary composite endpoint, the rates of clinical events, change in physiology, change in health status, and change in respiratory symptoms. (stanford.edu)
Corneal Transplantation1
Detection of allograft dysfunction1
  • The sensitivity, specificity, and positive/negative predictive values (PPV and NPV) of lung function for the detection of allograft dysfunction in these patients were measured. (bmj.com)
20161
Liver7
  • The total number of patients included in the study was 48, 27 of them referred from the Cardiothoracic Centre of Northern Greece (heart n=22, lung n=5) and 21 from the Transplant Unit of Aristotelian University of Thessaloniki, Hippokratio G.P. Hospital (liver n=21). (hippokratia.gr)
  • The global and regional markets (except the US) for 'Organ and Tissue Transplantation' in this report are analyzed by the following Product Segments - Organ Tranplantation (Heart, Kidneys, Liver, Pancreas, and Lungs). (prnewswire.com)
  • anti-HLA IgE in kidney, liver, lung and heart transplantation. (bvsalud.org)
  • Prospective assessment of pre-existing and de novo anti-HLA IgE in kidney, liver, lung and heart transplantation. (bvsalud.org)
  • Liver transplantation restores a better quality of life and helps patients in living healthy. (manipalhospitals.com)
  • The long-term survival rates are more than 90% for children's kidney transplantations and about 70% for children's heart and liver transplantations. (hus.fi)
  • Examples of this are heart-lung transplantations, liver and kidney transplantations, and liver and bowel transplantations. (hus.fi)
Kidney3
Rejection7
  • BACKGROUND: Lung function is altered by infection and rejection in patients who undergo heart-lung transplantation. (bmj.com)
  • Infection and rejection were accompanied by airflow obstruction, a rise in the slopes of the alveolar plateaus for nitrogen, hexafluoride sulphur and helium (SN2, SSF6, and SHe), and a decrease in the difference between SSF6 and SHe (delta S), total lung capacity (TLC), and lung transfer factor (TLCO). (bmj.com)
  • CONCLUSIONS: Indices of ventilation distribution, FEF25-75, and TLC have the best optimal sensitivity for the diagnosis of infection and rejection after heart-lung transplantation. (bmj.com)
  • Although aimed at protecting the host from infection, in the context of transplantation, this injury leads to allograft rejection. (medscape.com)
  • Antibody mediated rejection (ABMR) is a major factor limiting outcome after organ transplantation . (bvsalud.org)
  • Donor-Derived DNA Predicts Lung Transplant Rejection Before any clinical signs of graft failure are evident in patients who undergo lung transplant, experimental research suggests that donor-derived cell-free DNA could help predict a poor outcome. (medscape.com)
  • Usefulness of gene expression profiling of bronchoalveolar lavage cells in acute lung allograft rejection. (cdc.gov)
Dysfunction1
  • We report a case of I. limosus bacteremia in a patient in France who received a lung transplant and experienced chronic graft dysfunction and SARS-CoV-2 infection. (cdc.gov)
Bone Marrow1
  • 1 This includes human cells for transplantation such as haematopoietic stem cells from bone marrow, peripheral blood or cord blood. (who.int)
Cardiac surgery1
  • Thoracic oncology including cancer of lung and esophagus, heart and lung transplantation, minimally invasive thoracic surgery, lung and esophageal surgery, cardiac surgery including ventricular assist device (VAD) implantation. (unc.edu)
Disorders2
Surgery5
  • We work with clinicians in the Department of Surgery and the Corrigan Minehan Heart Center to recommend the best anesthetic services for patients undergoing all types of cardiac procedures. (massgeneral.org)
  • Organ transplantation is a life-saving surgery that replaces the diseased organ with a healthy organ from a living or deceased person. (manipalhospitals.com)
  • A heart transplant is a surgery to remove the diseased heart from a person and replace it with a healthy one from an organ donor. (manipalhospitals.com)
  • Surgery for lung cancer Lung cancer is the leading cause of cancer death in both men and women. (merckmanuals.com)
  • Access to transplantation entails more than the surgery itself, because success is measured by longer survival of the patient and a long-term improvement in the quality of life. (who.int)
Renal1
Undergo1
  • On August 10, Tolisha Alexander was the first UNC patient to undergo a lung transplant due to COVID-19. (unc.edu)
Ischemia-reperfusion injury1
  • Improved understanding of the mechanism of lung injury during brain death and during transition from donor to recipient may one day lead to techniques and preservation solutions that prevent ischemia-reperfusion injury. (medscape.com)
20191
  • Selection of lung transplant candidates in France in 2019]. (cdc.gov)
Clinical6
  • Clinical features of lung transplantation-related pathology can range from an absence of symptoms to signs and symptoms of respiratory distress and/or infection and are not detailed in this article. (medscape.com)
  • Our findings suggest that cross-circulation can serve as a complementary approach to clinical EVLP to recover injured donor lungs that could not otherwise be utilized for transplantation, as well as a translational research platform for immunomodulation and advanced organ bioengineering. (nature.com)
  • Extended criteria donor lungs and clinical outcome: results of an alternative allocation algorithm. (nature.com)
  • Normothermic ex vivo lung perfusion in clinical lung transplantation. (nature.com)
  • Image: A new method for heart transplantation in Institute for Clinical and Experimental Medicine (IKEM), using a pioneering method of organ retrieval that keeps the heart pumping outside the patient's body for several hours. (physio-pedia.com)
  • New Insights into Clinical and Mechanistic Heterogeneity of the Acute Respiratory Distress Syndrome: Summary of the Aspen Lung Conference 2021. (ucsf.edu)
Procedures3
Surgical2
  • Lung transplantation is the surgical removal of a healthy lung or part of a lung from a living person and then its transfer into someone whose lungs no longer function. (msdmanuals.com)
  • Advanced surgical techniques such as heart and lung transplantations are also developed at the centre. (lu.se)
Bilateral1
  • Double lung transplant (sometimes called bilateral lung transplant) - In this operation a patient receives two lungs. (gosh.nhs.uk)
Diseases1
Indications2
  • The indications for organ transplantations in children differ from those in adults. (hus.fi)
  • The most common indications for transplantation are congenital nephrotic syndrome (CNF), congenital malformations of the urinary tract and other congenital conditions. (hus.fi)
Bronchoscopy2
  • For patient education resources, see the Lung and Airway Center , as well as Heart and Lung Transplant and Bronchoscopy . (medscape.com)
  • A multi-center, controlled trial is required to validate the utility and safety of surveillance bronchoscopy in lung transplantation. (nih.gov)
Underwent1
Single Lung Transplant1
  • Single Lung Transplant - In this operation a patient receives one lung (left or right), although this is rarely carried out in children. (gosh.nhs.uk)
Donors2
Computed tomography1
  • The study aimed to evaluate the diaphragm morphology (height and thickness) in single-lung transplantation (SLTx), using computed tomography (CT), by assessing the evolution of the hemidiaphragm of the transplanted and the native side. (frontiersin.org)
Recipient7
  • CPT 33927 describes the implantation of a total replacement heart system (artificial heart) with recipient cardiectomy. (codingahead.com)
  • CPT 33935 describes a heart-lung transplant with recipient cardiectomy-pneumonectomy. (codingahead.com)
  • CPT 33945 describes a heart transplant, with or without recipient cardiectomy. (codingahead.com)
  • This screening is done to be sure that the organ is healthy enough for transplantation and the recipient does not have any medical conditions that would prohibit transplantation. (msdmanuals.com)
  • The transplantation of a "foreign" organ, despite meticulous matching for donor-recipient compatibility, leads to a complex adaptive and innate immune system-mediated injury. (medscape.com)
  • Indeed, the lung graft microbiome is affected by donor and recipient factors ( 6 ), but early posttransplant infections mainly involve the bacteria of the recipient rather than those of the donor ( 7 ). (cdc.gov)
  • Organ and tissue donation and transplantation is a medical procedure in which an organ is removed from one body and placed in the body of a recipient, to replace a damaged or missing organ or tissue. (who.int)
Severe1
Developed to transplant1
  • Since then, operations have been developed to transplant both lungs, a single lung, and even partial lung (lobes). (physio-pedia.com)
Congenital heart2
Organ and tissue2
Survival rates2
  • There are of course associated risks with transplantation, and while the early survival rates after the transplant are good, there can be no guarantees that any particular transplant will be a success. (gosh.nhs.uk)
  • Two recent series from North American centres with extensive experience in transplantation of CF patients have documented 1-yr survival rates of 50% versus 83% and 67% versus 96% among CF patients with and without B. cepacia , respectively 7 , 8 . (ersjournals.com)
Tissue1