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  • allograft
  • The donor lung (or allograft) is placed in the chest in the normal anatomic position. (cedars-sinai.edu)
  • Natural killer (NK) cells are innate lymphoid cells that have been increasingly recognised as important in lung allograft tolerance and immune defence. (bmj.com)
  • While the effects of immunosuppression agents on NK cells may currently be largely unintentional, further understanding of NK cell biology in lung allograft recipients may allow these cells to serve as biomarkers of graft injury and as therapeutic targets. (bmj.com)
  • organs
  • The journal's scope also addresses all aspects of advanced diseases of native thoracic organs, and includes articles with new insights into the immunology, pathogenesis, diagnosis, and management of heart failure and advanced lung disease. (efluids.com)
  • Lung transplantation involves removal of one or both diseased lungs from a patient and the replacement of the lungs with healthy organs from a donor. (encyclopedia.com)
  • This experimental option, not yet approved by the FDA, may lead to better ways to keep lungs (the most fragile of organs) stable during transplant. (nm.org)
  • The organization is responsible for the recovery of organs and tissue for medical transplantation in the service area, as well as for professional and public education on organ and tissue donation. (nm.org)
  • It was only after the invention of the heart-lung machine, coupled with the development of immunosuppressive drugs such as ciclosporin, that organs such as the lungs could be transplanted with a reasonable chance of patient recovery. (wikipedia.org)
  • One of the first mentions of the possibility of heart transplantation was by American medical researcher Simon Flexner, who declared in a reading of his paper on "Tendencies in Pathology" in the University of Chicago in 1907 that it would be possible in the then-future for diseased human organs substitution for healthy ones by surgery - including arteries, stomach, kidneys and heart. (wikipedia.org)
  • bronchiolitis obliterans
  • Bronchiolitis Obliterans Syndrome in Lung Transplantation presents the most current and up-to-date evidence regarding the diagnosis and management of BOS. (springer.com)
  • Written by an international group of expert authors, Bronchiolitis Obliterans Syndrome in Lung Transplantation is an important new text, that is essential reading for pulmonologists, primary care practitioners, respiratory care practitioners and clinical researchers. (springer.com)
  • infection
  • In some instances a bronchoscopy can help to isolate the cause of an infection in the lung. (netwellness.org)
  • CMV - CMV at one point was a common infection in lung transplant patients. (netwellness.org)
  • In the absence of safe and effective antiviral treatment for HCV infection in heart and lung transplant recipients, the management of these patients remains a challenge and must be considered on an individual basis. (hindawi.com)
  • These tests include those to analyze the general health of the body, including the child's heart, lung, and kidney function, the child's nutritional status, and the presence of infection. (nyhq.org)
  • Patients
  • The development of oral antifungal medications with activity against aspergillus have dramatically decreased the incidence of these infections in lung transplant patients. (netwellness.org)
  • Patients with stage III or stage IV sarcoidosis with cor pulmonale (right-sided heart failure) should be considered as early as possible for lung transplantation. (encyclopedia.com)
  • Patients who have diseases or conditions that may make them more susceptible to organ rejection are not selected for lung transplant. (encyclopedia.com)
  • While lung transplant is not a cure for lung disease, it has been shown to have an impressive record in prolonging life among patients with end-stage lung disease: 50 percent of patients live another five years, and 20 percent live another 10 years. (nm.org)
  • RxPG] New research published in the March issue of the Journal of the American College of Surgeons suggests that lung transplantation should be used with caution in patients older than 60 years and that the procedure is associated with high rates of mortality after one year in patients 70 and older. (rxpgnews.com)
  • The International Society for Heart and Lung Transplantation (ISHLT) reports that since 1985 the percentage of older patients receiving lung transplantation has increased steadily, with 24 percent of recipients in 2006 being older than age 60. (rxpgnews.com)
  • Lung transplantation is the therapeutic measure of last resort for patients with end-stage lung disease who have exhausted all other available treatments without improvement. (wikipedia.org)
  • Some patients, on a case by case basis, with lung cancer or other cancers, may be allowed. (wikipedia.org)
  • PVOD may occur in patients with associated diseases such as HIV, bone marrow transplantation, and connective tissue diseases. (wikipedia.org)
  • She has specialized in the medical care of heart transplant patients and is a past president of The International Society for Heart & Lung Transplantation. (wikipedia.org)
  • tissue
  • It is estimated that it takes an average of one to two years to receive a suitable donor lung, and the wait is made less predictable by the necessity for tissue match. (encyclopedia.com)
  • Thoracic surgeons remove small wedges of damaged lung tissue in order to help the remaining lung tissue function more efficiently. (nm.org)
  • Individuals who donate a part of a lung can live healthy lives with the remaining lung tissue. (nyhq.org)
  • LAM involves lung tissue infiltration with smooth muscle-like cells with mutations of the tuberous sclerosis complex gene (TSC2). (wikipedia.org)
  • A Hiatal hernia can cause Bronchiectasis when the stomach acid that is aspirated into the lungs causes tissue damage. (wikipedia.org)
  • OPTN
  • OPTN is a unique public-private partnership that links all of the professionals involved in the donation and transplantation system. (nm.org)
  • Once OPTN receives the data from local hospitals, people waiting for a lung transplant are placed on a waiting list and given a "status" code. (nyhq.org)
  • acute
  • Three months after the moratorium on heart transplantation, English became inspired by a visit to his friend Philip Caves, at Stanford University, who had developed the technique of transvenous myocardial biopsy to detect acute organ rejection at an early stage, and was then Chief Resident in Shumway's unit. (wikipedia.org)
  • ventilation
  • After the induction of anesthesia, intubation with a left-sided double-lumen tube, and insertion of all invasive monitors and a TEE probe, lung isolation is achieved, and one-lung ventilation (OLV) is established. (springer.com)
  • procedure
  • As of 2016, the most common procedure is to take a functioning heart, with or without transplanting one or both lungs at the same time, from a recently deceased organ donor (brain death is the standard) and implanting it into the patient. (wikipedia.org)
  • contrast
  • By contrast, traditional ventilators can damage lungs by pushing air into them. (nm.org)
  • surgeons
  • Although Hardy was a respected surgeon who had performed the world's first human-to-human lung transplant a year earlier, author Donald McRae states that Hardy could feel the "icy disdain" from fellow surgeons at the Sixth International Transplantation Conference several weeks after this attempt with the chimpanzee heart. (wikipedia.org)
  • chest
  • The incisions are then closed and two more chest tubes are placed around the new lung to help it re-expand with air. (cedars-sinai.edu)
  • The most common is the chest x ray (CXR), which takes an internal picture of the chest including the lungs, ribs, heart, and the contours of the major vessels of the chest. (encyclopedia.com)