AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsInformation ScienceNamed GroupsHealth CareGeographicals
Lung TransplantationPrimary Graft DysfunctionBronchiolitis ObliteransGraft RejectionHeart-Lung TransplantationKidney TransplantationLungGraft SurvivalTransplantation, HomologousTissue DonorsTreatment OutcomeLiver TransplantationLung DiseasesTransplantationImmunosuppressive AgentsHeart TransplantationTissue and Organ ProcurementBone Marrow TransplantationRetrospective StudiesWaiting ListsHematopoietic Stem Cell TransplantationCollagen Type VPostoperative ComplicationsTime FactorsImmunosuppressionDelayed Graft FunctionHistocompatibility TestingLiving DonorsDonor SelectionIslets of Langerhans TransplantationCystic FibrosisLung NeoplasmsFollow-Up StudiesRespiratory AspirationSurvival AnalysisTransplantation ConditioningTransplantation, AutologousSurvival RateRisk FactorsTransplantation ImmunologyOrgan TransplantationPulmonary FibrosisGraft vs Host DiseaseCytomegalovirus InfectionsLung InjuryHLA AntigensBronchoalveolar Lavage FluidPrognosisTransplantsBronchial DiseasesBronchoalveolar LavageLung Diseases, InterstitialStem Cell TransplantationHistocompatibilityCohort StudiesTacrolimusCyclosporineBronchoscopyOrgan PreservationKidney Failure, ChronicTransplantation, HeterotopicKaplan-Meier EstimateHypertension, PulmonaryProspective StudiesCarcinoma, Non-Small-Cell LungExtracorporeal Membrane OxygenationAcute DiseaseRespiratory Function TestsImmunocompromised HostRecurrenceProportional Hazards ModelsTransplantation ChimeraTransplantation, IsogeneicPatient SelectionPancreas TransplantationReperfusion InjuryIdiopathic Pulmonary FibrosisPostoperative PeriodUnited StatesRegistriesFatal OutcomeCytomegalovirusCell TransplantationForced Expiratory VolumeGanciclovirMultivariate AnalysisBiopsyBurkholderia gladioliAcute Lung InjuryPulmonary EmphysemaBronchiOutcome Assessment (Health Care)Severity of Illness IndexMycosesIncidenceAge FactorsBiological MarkersPneumonectomyLymphoproliferative DisordersFetal Tissue Transplantation
Recipients2023ImmunosuppressionDonorCysticAllograftUnderwentInterstitial lung diseasesLong-term outcomesIdiopathic PulmonarBilateralDonorsMortalityClinicalCardiac transplantationPulmonary fibrosisRejection after lung transplantation2020DysfunctionBrigham and WomeSurgeonsSelection of lung transplant candidatesChronicAdultGRAFTPancreasOrgans2019FrailtyDiseasesPediatricRegistryExtracorporeal membrane oxAcute rejectionBronchiolitis obliterans syndromeThoracicEarly post-transplantSurvival outcomesSingle-lung transplantPostoperativeCentersMechanical circulatory supportRespiratoryYear after transplantationComputed tomographyHeart and lungAccess to transplantationDisease
Recipients23
  • He was part of a team that first reported a link between Cyclosporine A, prednisone and osteoporosis in heart transplant recipients, and published an article on the relationship between experience and outcomes in heart transplantation. (wikipedia.org)
  • bronchopulmonary infection in a multiple-traumatized patient and 2 lung transplant recipients in France. (cdc.gov)
  • The reasons are manifold, including the paucity of both donors and recipients, the investment required in developing paediatric lung transplant centres and scepticism about the outcome. (ersjournals.com)
  • Today there are more recipients waiting for organ transplants than there are organs available. (brighamandwomens.org)
  • With a new antiviral treatment regimen, could it be possible to transplant these organs, prevent the establishment of hepatitis C in the recipients, and produce an excellent outcome in patients? (brighamandwomens.org)
  • Via genome sequencing of both lung transplant recipients and donors, we examine genetic ancestral markers that are associated with graft rejection and dysfunction. (nih.gov)
  • These sites collect longitudinal bio-samples and clinical data in heart- and lung-transplant recipients for the GRAFT consortium. (nih.gov)
  • The recipients of allografts from those 47 donors had higher Lung Allocation Scores and more frequently underwent double lung transplantation (43/47). (aats.org)
  • At Henry Ford Transplant, our expert surgeons continue to find new, safer surgical techniques for transplant recipients and living donors. (henryford.com)
  • Your donation will be used to help IPTA to promote the advancement of the science and practice of transplantation in children worldwide and to serve as a unified voice for the special needs of pediatric transplant recipients. (tts.org)
  • Today, a main focus of the transplant community is the long-term outcomes of lung and heart allograft recipients. (terasaki.org)
  • The impact of pre-lung transplant (LT) pan-drug-resistant Pseudomonas aeruginosa (PDR PsA) colonization on post-LT mortality and bronchiolitis obliterans syndrome (BOS) rates in cystic fibrosis (CF) LT recipients (LTR) is unknown. (atcmeetingabstracts.com)
  • METHODS: Pediatric first-time LTx recipients transplanted between January 2000 and December 2020 were identified in the United Network for Organ Sharing Registry to compare post-transplant survival according to ECMO support at time of transplant. (bvsalud.org)
  • Cystic fibrosis (CF) lung transplant recipients (LTRs) exhibit a disproportionately high rate of life-threatening invasive aspergillosis (IA). (stanfordchildrens.org)
  • Pereira MR, Mohan S, Cohen DJ COVID-19 in solid organ transplant recipients: initial report from the US epicenter. (britishjournalofnursing.com)
  • Outcomes of telehealth care for lung transplant recipients. (britishjournalofnursing.com)
  • Immunosuppression for lung transplant recipients. (britishjournalofnursing.com)
  • All solid organ transplant recipients are at risk, and lung transplant recipients are among those at highest risk. (secondwindstl.org)
  • The immune system plays a role in detecting early pre-cancerous lesions and eliminates them or limits their growth so that when transplant recipients are immunosuppressed their immune system's mechanisms to detect cancers or to eliminate them may be impaired. (secondwindstl.org)
  • These cases generally occur in recipients who have never been infected with Epstein-Barr virus and have no immunity to the virus who receive lungs from a donor who has been infected with the virus. (secondwindstl.org)
  • Organ Transplantation.2 These Guiding Principles - whose emphases include voluntary donation, noncommercialization, genetic relation of recipients to donors and a preference for cadavers over living donors as sources - have considerably influenced professional codes, national, state and provincial legislation, and the policies of intergovernmental organizations. (who.int)
  • Despite advances in the field, transplant recipients may face several avoidable risks. (who.int)
  • Prevalence of pre-transplant anti-HLA antibodies and their impact on outcomes in lung transplant recipients. (medscape.com)
20231
Immunosuppression7
Donor14
  • Patients awaiting lung transplantation face high wait-list mortality, as injury precludes the use of most donor lungs. (nature.com)
  • Although ex vivo lung perfusion (EVLP) is able to recover marginal quality donor lungs, extension of normothermic support beyond 6 h has been challenging. (nature.com)
  • Our findings suggest that cross-circulation can serve as a complementary approach to clinical EVLP to recover injured donor lungs that could not otherwise be utilized for transplantation, as well as a translational research platform for immunomodulation and advanced organ bioengineering. (nature.com)
  • Extended criteria donor lungs and clinical outcome: results of an alternative allocation algorithm. (nature.com)
  • The goal of this research is to better inform pre- and post-transplant clinical management and further refine donor-recipient organ matching to improve long-term outcomes and survival in lung transplant patients. (nih.gov)
  • The resources for the GRAfT-GTD study provide support at all clinical sites for patient recruitment, enrollment and bio-sample collection, while also supporting the laboratory of transplant genomics at NHLBI to perform measurements of ddcfDNA (donor derived - cell free DNA), computational analysis, host and manage the biorepository of clinical data and all bio-samples, and the data coordinating center for GRAfT at NHLBI. (nih.gov)
  • Our recent research has also explored recipient and donor variables in the success or failure of lung transplants , and ways in which national healthcare delivery systems impact lung transplant outcomes for CF patients. (hopkinsmedicine.org)
  • Thanks to a living-donor kidney transplant a friend and colleague, a music teacher and vocalist continues to share her gift. (henryford.com)
  • The lives of three Los Angeles-area kidney transplant patients were transformed by one of the West Coast's first three-way living donor kidney transplant chains, made possible through the generosity of a non-directed, altruistic kidney donor from New York City -- announced today at a joint news conference. (news-medical.net)
  • The kidney from the New York donor was delivered by the New York Organ Donor Network to UCLA's operating room for the July 30 transplant after being removed by Dr. Joseph Del Pizzo, director of laparoscopic and minimally invasive surgery in urology and associate professor of urology at NewYork-Presbyterian/Weill Cornell. (news-medical.net)
  • Hil started the registry when his youngest daughter needed a transplant and tests revealed that her body would have rejected his kidney, as well as kidneys from three uncles and the anonymous New York donor who ultimately started the chain at UCLA. (news-medical.net)
  • Donor chains have enormous potential to expand the donor pool and to provide better matched organs for the many individuals who are in desperate need of lifesaving transplants," Kapur said. (news-medical.net)
  • Kidney donor chains could have a significant impact on the country's organ donor shortage," said Dr. David Serur, medical director of The Rogosin Institute Transplant Center and associate professor of clinical medicine at NewYork-Presbyterian/Weill Cornell. (news-medical.net)
  • While computed tomography (CT) is the gold standard, it is rarely used in an organ-donor context, and chest X-ray (CXR) may offer a practical and accurate solution in estimating lung volumes for donor and recipient size matching. (bvsalud.org)
Cystic10
Allograft13
  • INTRODUCTION: Development of chronic lung allograft dysfunction is a limiting factor for post-lung transplant survival. (smw.ch)
  • We evaluated whether the dose of the immunosuppressant mycophenolate mofetil or plasma concentrations of the active metabolite mycophenolic acid affect the development of chronic lung allograft dysfunction. (smw.ch)
  • An event-time-analytical Cox proportional-hazards regression model with time-varying-covariates (18,431 measurements for MPA, mycophenolate mofetil dosage, lymphocytes) was used to predict chronic lung allograft dysfunction, with adjustment for sociodemographic factors and lung function at baseline. (smw.ch)
  • RESULTS: 37 patients did not develop chronic lung allograft dysfunction (age 41.3 ± 15.6 years, baseline FEV1 95.5 ± 19.1% predicted) and 34 patients developed chronic lung allograft dysfunction (age 50.9 ± 13.3 years, baseline FEV1 102.2 ± 25.4% predicted). (smw.ch)
  • 0.001), but only the traditional risk factor age predicted chronic lung allograft dysfunction. (smw.ch)
  • Continuously measured mycophenolic acid did not predict chronic lung allograft dysfunction (hazard ratio 0.98, 95% confidence interval 0.90-1.06, p = 0.64 over a period of 382.97 patient-years). (smw.ch)
  • CONCLUSION: Mycophenolate mofetil dosage and mycophenolic acid were not associated with chronic lung allograft dysfunction development. (smw.ch)
  • Chronic lung allograft dysfunction: Definition, diagnostic criteria, and approaches to treatment-A consensus report from the Pulmonary Council of the ISHLT. (smw.ch)
  • In our cohort of patients, we examine demographic and clinical characteristics, as well as differential levels of cell free DNA, to explore outcomes of allograft failure, acute cellular rejection, and chronic lung allograft dysfunction in individuals of European and non-European ancestry. (nih.gov)
  • However, even early post-transplant survival (within the first post-transplant year) needs improvement, as early graft failure still accounts for many allograft losses. (terasaki.org)
  • Prospective trial data in other indications -- tacrolimus is already approved for preventing allograft rejection in liver, kidney, pancreas, bowel, and heart transplantation -- supported the new approval, the FDA added. (medpagetoday.com)
  • Short Airway Telomeres are Associated with Primary Graft Dysfunction and Chronic Lung Allograft Dysfunction. (ucsf.edu)
  • The Association Between Frailty and Chronic Lung Allograft Dysfunction After Lung Transplantation. (ucsf.edu)
Underwent4
Interstitial lung diseases1
  • What are the barriers patients with interstitial lung diseases may face in obtaining a timely and accurate diagnosis? (medscape.com)
Long-term outcomes1
  • APO is now exploring whether these novel genomic approaches risk stratify other pulmonary patients for long-term outcomes. (nih.gov)
Idiopathic Pulmonar2
  • With a longstanding interest in biomedical research and a passion for better understanding one of the least regenerative organs in the body, the lung, he has spent the past four years helping to uncover some of the mechanisms that may drive a lung disease currently without a cure, idiopathic pulmonary fibrosis. (lu.se)
  • The focus of my Ph.D. studies has been lung fibrosis, and more specifically, idiopathic pulmonary fibrosis (IPF). (lu.se)
Bilateral5
Donors4
  • Takashi Harano, MD, and colleagues at Keck Medicine, University of Southern California, analyzed lung transplantation data from April 2020 to June 2022, to identify the early outcomes for patients who received lungs from COVID-19-positive donors. (aats.org)
  • Lungs were transplanted from 47 donors. (aats.org)
  • This study reports that carefully selected lung allografts from COVID-19-positive donors had comparable early post-transplant outcomes to the lung allografts from COVID-19-negative donors. (aats.org)
  • Biofire pneumonia panel in lung donors: faster detection but limited pathogens. (ucsf.edu)
Mortality7
  • Frailty is associated with morbidity and mortality in abdominal organ transplantation but has not been examined in lung transplantation. (nih.gov)
  • The family Microascaceae includes genera Microascus and Scopulariopsis , opportunistic fungi that have caused respiratory infection associated with poor outcome and an attributable mortality rate of 85%-100% ( 1 , 2 ). (cdc.gov)
  • Invasive pulmonary aspergillosis (IPA) is associated with high morbidity and mortality rates in immuno-compromised patients including those undergoing hematological stem cell or solid organ transplantation (particularly lung transplants) and some patients in critical care, including those with COVID-19- or influenza-associated pulmonary aspergillosis. (globenewswire.com)
  • The study will compare the time to a composite endpoint of relative decline in lung function [10% relative decline in forced vital capacity (FVC), first respiratory hospitalization, lung transplantation, or all-cause mortality] The secondary objectives will be to examine the effect of NAC on the components of the primary composite endpoint, the rates of clinical events, change in physiology, change in health status, and change in respiratory symptoms. (stanford.edu)
  • Instead, the primary evidence for the drug's effectiveness in this setting came from the federal government's transplant registry , along with Social Security mortality records. (medpagetoday.com)
  • The primary outcome was all-cause mortality. (northumbria.ac.uk)
  • Morbidity and mortality related to pneumonia and TRACHEOBRONCHITIS in ICU after lung transplantation. (medscape.com)
Clinical9
  • Laffel had previously served as an attending physician in the cardiac transplantation program at Brigham and Women's Hospital, as a founding editor of the peer-reviewed journal, Quality Management in Health Care, a consultant to healthcare provider organizations and President of Clinical Solutions. (wikipedia.org)
  • His clinical research has primarily been directed toward surgical issues in complex congenital heart care and cardiac transplantation (focusing on advances with operative techniques, outcomes research and transplantation for congenital heart disease), with a particular emphasis on the development of mechanical ventricular assist devices for children, as well as stem-cell based valved conduits for pediatric application. (chop.edu)
  • Normothermic ex vivo lung perfusion in clinical lung transplantation. (nature.com)
  • APO is also planning a clinical trial to assess whether early detection and treatment of rejection improves survival in lung transplant patients and also engaged in additional studies to understand molecular mechanisms of transplant rejection. (nih.gov)
  • He performs health services and outcomes research focused on understanding and improving the lives and care of patients with advanced lung disease and is actively involved in clinical trials to improve outcomes in interstitial lung disease. (stanford.edu)
  • Techniques of successful clinical double-lung transplantation. (medigraphic.com)
  • As a leading medical research center for organ and bone marrow stem cell transplants, Henry Ford Transplant offers access to advanced clinical trials in every type of transplant program. (henryford.com)
  • Clinical Transplantation. (elsevierpure.com)
  • Background: Pulmonary vascular disease (PVD) represents an important clinical indication for lung transplant (LTx) in infants, children, and adolescents. (bvsalud.org)
Cardiac transplantation1
  • Conservative management with medications and/or lung and cardiac transplantation are therapeutic approaches that can offer quality-of-life improvement. (medscape.com)
Pulmonary fibrosis2
Rejection after lung transplantation1
20201
  • Survival in adult lung transplantation: where are we in 2020? (smw.ch)
Dysfunction1
Brigham and Wome2
  • The Brigham and Women's Hospital Lung Transplant Program, the largest program in New England over the past decade, is committed to providing the most innovative, effective, and compassionate care to our patients with advanced lung disease. (brighamandwomens.org)
  • A pioneer in lung transplantation, Brigham and Women's Hospital continues to lead with the resources, research, and expertise to offer life-saving care. (brighamandwomens.org)
Surgeons4
  • Our experienced thoracic and transplant surgeons perform single and double lung transplants and heart-lung transplants. (brighamandwomens.org)
  • A team of infectious disease experts, transplant physicians and surgeons from the Brigham proved, with an effectiveness of 100 percent, that it is. (brighamandwomens.org)
  • Wildevuur CR, Benfield JR. A review of 23 human lung transplantations by 20 surgeons. (medigraphic.com)
  • So in the Department of transplantation, the fact that our surgeons and our nephrologists are able to work so closely together with all of the other support staff that make transplant happen is extremely important. (mayoclinic.org)
Selection of lung transplant candidates2
Chronic1
  • Chronic lung infections with Aspergillus can leave patients with extensive and permanent lung damage, requiring a lifetime of antifungal treatment. (globenewswire.com)
Adult5
  • Lung transplantation has emerged as an accepted therapy for end-stage lung disease in adult patients, whereas in the paediatric population it is still controversial [ 1 - 3 ]. (ersjournals.com)
  • For children and adult with advanced lung diseases, transplantation is often the only treatment. (nih.gov)
  • [9] [10] A registry maintained by ELSO of nearly 51,000 people that have received ECMO has reported outcomes with 75% survival for neonatal respiratory failure, 56% survival for pediatric respiratory failure, and 55% survival for adult respiratory failure. (wikipedia.org)
  • We have studied methods of diagnosing and managing pulmonary arteriovenous malformations as well as the outcomes of adult CF patients who are infected with multiple antibiotic-resistant Pseudomonas aeruginosa. (hopkinsmedicine.org)
  • Registry of the international society for heart and lung transplantation: twenty-second official adult lung and heart-lung transplant report-2005. (medigraphic.com)
GRAFT4
  • The Genomic Alliance for Transplantation (GRAfT), established by Dr. Hannah Valantine in 2015 , is a consortium of NHLBI and 8 heart and lung transplant programs located in 5 hospitals within geographic proximity of the National Institutes of Health (NIH), directed by Dr. Hannah Valantine. (nih.gov)
  • Unfortunately, he developed graft vs. host disease (GVHD) after the bone marrow transplant, resulting in severe and progressive interstitial lung disease secondary to GVHD. (tts.org)
  • CT12 Chapter 5: Factors Affecting Graft Survival Within 1-year Post-Transplantation in Heart and Lung Transplant: An Analysis of the OPTN/UNOS Registry. (terasaki.org)
  • Factors Affecting Graft Survival Within 1-year Post-Transplantation in Heart and Lung Transplant: An Analysis of the OPTN/UNOS Registry. (terasaki.org)
Pancreas3
  • Our lab also has a longstanding interest in pancreas transplants and has conducted research to establish guidelines for diagnosing antibody-mediated rejection of pancreas allografts-updated Banff grading schema. (hopkinsmedicine.org)
  • Henry Ford Transplant offers transplantation of the liver , kidney , pancreas , intestine and multivisceral organs , heart , lung and bone marrow stem cell . (henryford.com)
  • I have primary responsibility for kidney and pancreas transplant patients, but I also work with the heart, liver, and lung transplant population. (mayoclinic.org)
Organs11
  • Replacement with a healthy lung can promote the recovery of the diaphragm to its anatomical morphology, reinforcing the close relationship between these two organs. (frontiersin.org)
  • Sykes, M. & Sachs, D. H. Transplanting organs from pigs to humans. (nature.com)
  • Survival after lung transplantation is still well below that of transplantation of other solid organs but has increased over the past decades [ 2 , 5 - 7 ]. (ersjournals.com)
  • And while the current opioid crisis has produced more available organs for transplantation, those with hepatitis C viral infection have previously been considered ineligible. (brighamandwomens.org)
  • Transplantation of human organs and tissues1 saves many lives and restores essential functions in circumstances when no medical alternative of comparable effectiveness exists. (who.int)
  • The transplantation of solid organs, such as kidney, liver, heart or lung, is increasingly a regular component of health care in all countries, and is no longer a feature of health care in high-income countries alone. (who.int)
  • Of the 70 000 or so solid organs transplanted annually, 50 000 are kidney replacements, more than one-third of the latter operations are done in low- or medium-income countries. (who.int)
  • Nonetheless, the transplantation of organs and tissues does raise ethical concerns. (who.int)
  • The persistent and widening gap between patients' need for organs and the number available for transplantation has become a major concern to many Member States. (who.int)
  • The supply of cadaveric organs is limited by an inadequately informed and educated public, inefficient or non-existent organizations for procuring transplant material, and cultural and religious barriers in some countries. (who.int)
  • Successful transplantation of organs and living tissues depends on continued medical follow-up and the patient's compliance with a regimen of immunosuppressive drugs. (who.int)
20191
  • La información más reciente sobre el nuevo Coronavirus de 2019, incluidas las clínicas de vacunación para niños de 6 meses en adelante. (stanfordchildrens.org)
Frailty5
  • To examine the construct and predictive validity of frailty phenotypes in lung transplant candidates. (nih.gov)
  • We estimated the association between frailty and disability using the Lung Transplant Valued Life Activities disability scale. (nih.gov)
  • We estimated the association between frailty and risk of delisting or death before transplant using multivariate logistic and Cox models, respectively. (nih.gov)
  • By either measure, frailty correlated more strongly with exercise capacity and grip strength than with lung function. (nih.gov)
  • Frailty is prevalent among lung transplant candidates and is independently associated with greater disability and an increased risk of delisting or death. (nih.gov)
Diseases2
  • Right now there is very limited treatment modalities available for interstitial lung disease and COPD, even as the incidence of these diseases are growing with a fairly significant number of patients suffering from them. (apollohospitals.com)
  • Confounders can and often do drive the transmission of mycobacterial diseases, as well as impact surveillance and treatment outcomes. (bvsalud.org)
Pediatric6
  • From 2008-2013, he served as Chief of Pediatric Cardiovascular Services and the David Wallace-Starr Foundation Professor at Weill Medical College of Cornell University, as well as Surgical Director of the Pediatric Heart Transplant Program at the Columbia University campus. (chop.edu)
  • Our doctors work with pediatric specialists at Children's Hospital of Michigan to provide seamless care for children who need heart, liver and kidney transplants. (henryford.com)
  • The International Pediatric Transplant Association (IPTA) is a professional organization of individuals in the field of pediatric transplantation. (tts.org)
  • The purpose of the Association is to advance the science and practice of pediatric transplantation worldwide in order to improve the health of all children who require such treatment. (tts.org)
  • The Association is dedicated to promoting technical and scientific advances in pediatric transplantation and to advocating for the rights of all children who need transplantation. (tts.org)
  • The overarching goal of this new initiative is to facilitate and improve the quality of publications being sent by our membership to transplant journals, especially Pediatric Transplantation . (tts.org)
Registry3
  • In this chapter, we review the experience of heart and lung transplantation as reported to the Organ Procurement Transplant Network/United Network of Organ Sharing registry and investigate the factors responsible for causing failure in the first post-transplant year. (terasaki.org)
  • The USnational registry for childhood interstitial and diffuse lung disease: Report of study design and initial enrollment cohort. (stanfordchildrens.org)
  • International Registry in Organ Donation and Transplantation. (britishjournalofnursing.com)
Extracorporeal membrane ox4
Acute rejection2
Bronchiolitis obliterans syndrome1
  • 1- and 5-yr patient survival rates were 72.1% and 60.6%, respectively, and 52.6% of patients were found to be free from bronchiolitis obliterans syndrome at 5 yrs post-transplant. (ersjournals.com)
Thoracic3
  • The Department for Thoracic Surgery at the Medical University of Vienna (Vienna, Austria) is one of the largest lung transplant centres in Europe, with the highest per head transplantation rate worldwide (14.1 per million inhabitants) [ 9 ]. (ersjournals.com)
  • In the first year after the transplant, the majority of cases are thoracic. (secondwindstl.org)
  • In contrast to the early cases of PTLD after lung transplantation, those that manifest after the first year are usually extra-thoracic, often presenting in the abdomen or pelvis with abdominal pain, gastrointestinal bleeding, or non-healing ulcers. (secondwindstl.org)
Early post-transplant1
  • Trends indicate that sicker patients are increasingly being transplanted, thereby limiting improvements in early post-transplant survival. (terasaki.org)
Survival outcomes1
  • Both the United States and United Kingdom have similar early survival outcomes, suggesting important dissemination of best practices internationally. (northumbria.ac.uk)
Single-lung transplant1
  • Single Lung Transplant - In this operation a patient receives one lung (left or right), although this is rarely carried out in children. (gosh.nhs.uk)
Postoperative3
  • Erasmus ME, van der Bij W. Death after lung transplantation: improving long term survival despite perilous early postoperative years. (smw.ch)
  • FRIDAY, June 19, 2015 (HealthDay News) - For patients undergoing lung transplantation, six-minute walk distance (6MWD) predicts postoperative survival, according to a study published online June 11 in the American Journal of Respiratory and Critical Care Medicine . (ehealth-news.com)
  • Anthony W. Castleberry, M.D., from the Duke University Medical Center in Durham, N.C., and colleagues examined the correlation between 6MWD and postoperative survival following lung transplantation. (ehealth-news.com)
Centers5
  • In the last five years, our Program's one-year outcomes have consistently exceeded Centers for Medicare & Medicaid Services (CMS) benchmarks, and our three-year survival rates routinely meet targeted thresholds. (brighamandwomens.org)
  • Generally, it is used either post-cardiopulmonary bypass or in late-stage treatment of a person with profound heart and/or lung failure, although it is now seeing use as a treatment for cardiac arrest in certain centers, allowing treatment of the underlying cause of arrest while circulation and oxygenation are supported. (wikipedia.org)
  • In the United Kingdom , veno-venous ECMO deployment is concentrated in designated ECMO centers to potentially improve care and promote better outcomes. (wikipedia.org)
  • The hope is that this marks the first of many such collaborations among the nation's transplant centers," said Dr. Sandip Kapur, chief of transplant surgery and associate professor of surgery at NewYork-Presbyterian/Weill Cornell. (news-medical.net)
  • Here our own experience of just around 200 lung transplants in all, across the country in all medical centers, should set the perspective for where we are and how far behind we are. (apollohospitals.com)
Mechanical circulatory support1
Respiratory1
  • Case 2 occurred in a 61-year-old lung transplant recipient who sought care for respiratory deterioration and decline in respiratory function. (cdc.gov)
Year after transplantation1
  • METHODS: In this retrospective cohort study we recruited 71 patients with a lung transplant between 2010 and 2014 which survived the first year after transplantation up to 1 July 2021. (smw.ch)
Computed tomography1
  • The study aimed to evaluate the diaphragm morphology (height and thickness) in single-lung transplantation (SLTx), using computed tomography (CT), by assessing the evolution of the hemidiaphragm of the transplanted and the native side. (frontiersin.org)
Heart and lung4
Access to transplantation4
  • Access to transplantation is limited in low- and many medium-income countries, where the rate of transplants remains far below that of richer nations. (who.int)
  • Even between countries which have similar levels of health resources, patients' access to transplantation also varies. (who.int)
  • Moreover, for patients who have kidney failure, access to transplantation is reduced when funds are spent on other forms of treatment that are less cost-effective. (who.int)
  • Access to transplantation entails more than the surgery itself, because success is measured by longer survival of the patient and a long-term improvement in the quality of life. (who.int)
Disease11
  • The influence of lung disease on the diaphragm has been poorly studied. (frontiersin.org)
  • Lung transplantation (LTx), by replacing a diseased lung with a healthy one, is an interesting model to evaluate the evolution of the diaphragmatic morphology before and after transplantation in the context of lung disease. (frontiersin.org)
  • Silicosis is a progressive, incurable, fibrotic lung disease caused by inhalation of respirable crystalline silica dust produced in industries such as construction, quarrying, and coal mining ( 2 ). (cdc.gov)
  • Joshua Mooney, MD, MS, is a board certified pulmonologist and critical care physician who specializes in the care of interstitial lung disease and lung transplant patients. (stanford.edu)
  • Transplant Infectious Disease. (elsevierpure.com)
  • INTRODUCTION: Childhood interstitial and diffuse lung disease (chILD) encompasses a broad spectrum of rare disorders. (stanfordchildrens.org)
  • After transplantation, lymphoma is often called post-transplant lymphoproliferative disease or PTLD because this represents the full spectrum of lymphoid proliferations seen after transplantation, ranging from an infectious mononucleosis-like illness to malignant non-Hodgkin's lymphoma. (secondwindstl.org)
  • For example, in developing and developed countries alike, kidney transplantation not only yields survival rates and quality-of-life that are far superior to those obtained with other treatments for end-stage renal disease, such as haemodialysis, but is also less costly in the long run. (who.int)
  • Elevated α-defensin levels in plasma and bronchoalveolar lavage fluid from patients with myositis-associated interstitial lung disease. (medscape.com)
  • Right now, the most common theory is that the disease could potentially be triggered by an initial injury to the lung epithelium which in turn induces an abnormal repair pathway, leading to d amage of the lung. (lu.se)
  • However, in lung fibrosis, these molecules are abnormally active and are responsible for causing disease characteristics like tissue scarring. (lu.se)