• C9orf43 is expressed in many different tissues during the fetal and adult developmental stages according to NCBI's EST Profile. (wikipedia.org)
  • The physical substance of the human organism, composed of living cells and extracellular materials and organized into tissues, organs, and systems. (rincondelvago.com)
  • MGMT expression is decreased in some tumor tissues, and lack of activity has been observed in some cell lines. (aacrjournals.org)
  • All normal tissues and expressing cancer cell lines were unmethylated, whereas nonexpressing cancer cell lines were methylated. (aacrjournals.org)
  • HGF is produced and secreted by adjacent stromal and mesenchymal cells, it contributes to the development of epithelial organs in a paracrine fashion, exerts regenerative effects on epithelia in the liver, kidney, lung, and other tissues, and promotes the regression of fibrosis in numerous organs ( 7 , 8 ). (spandidos-publications.com)
  • The distribution of oestrogen receptors in mammalian tissues suggests that oestrogens could have a significant role in orchestrating a number of pathways in living organisms during development and adulthood. (biomedcentral.com)
  • Infection by VMV and CAEV can lead to Visna/Maedi (VM) and Caprine Arthritis-Encephalitis (CAE) respectively, slow progressive inflammatory diseases primarily affecting the lungs, nervous system, joints and mammary glands. (mdpi.com)
  • Typical of mammalian structure, the human body shows such characteristics as hair, mammary glands, and highly developed sense organs. (rincondelvago.com)
  • Located in the sweat glands, mammary glands, & salivary glands. (freezingblue.com)
  • In gliomas and colorectal carcinomas, aberrant methylation was detected in 40% of the tumors, whereas in non-small cell lung carcinomas, lymphomas, and head and neck carcinomas, this alteration was found in 25% of the tumors. (aacrjournals.org)
  • L. C. Strong breeds a Bagg albino with an albino from Little 's stock and starts the first of many tumor-prone strains, called the A strain, known for mammary and lung tumors. (jax.org)
  • When evaluating with microsatellite steady tumors, there is normally some proof for Kitty least partialC immunological development control in MSI malignancies, like (I) the thick regional lymphocytic infiltration (Crohn's-like lymphocytic response), (II) the elevated apoptotic growth cell amount, and (3) the low amount of isolated metastases that (4) network marketing leads to an improved general individual success [1]C[3]. (immune-source.com)
  • What was special about Dolly is that her "parents" were actually a single cell originating from mammary tissue of an adult ewe. (wptv.com)
  • The Misharin laboratory leveraged unique tissue resources available via several established translational research programs in the division of pulmonary and critical care medicine and the Simpson Querrey Lung Institute for Translational Science to generate new data for the Human Lung Cell Atlas. (rna-seqblog.com)
  • Goblet cells exist within the simple columnar epithelial tissue. (freezingblue.com)
  • This rich resource of chromatin accessibility in the mouse brain at single cell resolution will build a basis for understanding the gene regulatory architecture of the mammalian brain and its role in tissue function and disease. (ucsd.edu)
  • We focused on breast tissue because, in cattle, BLV DNA and protein have been found to be more abundant in mammary epithelium than in lymphocytes. (cdc.gov)
  • We focused on breast tissue because, in cattle, BLV DNA and p24 were detected in mammary tissue, whereas only BLV DNA was detected in lymphocytes ( 10 ). (cdc.gov)
  • Conditional Met KO mice were generated using Cre‑loxP methodology and characterization of these mice indicated that the HGF‑Met signaling pathway is essential in regeneration, protection, and homeostasis in various tissue types and cells. (spandidos-publications.com)
  • Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis. (academicinfluence.com)
  • Locally advanced squamous cell carcinomas of the head and neck, (excluding lip) in combination with concurrent chemoradiation. (nih.gov)
  • Background: Stromal cells are a functionally important component of human carcinomas. (immune-source.com)
  • It has recently been reported that Madin-Darby canine kidney (MDCK) epithelial cells silenced for the polarity gene scribble ( scrib KD cells) are eliminated in the presence of wild-type MDCK cells 23 , while they are viable on their own 23 . (nature.com)
  • Cancer types that have been well documented in literature to be related with environmental exposure include the reproductive system, breast, lung, kidney, pancreas, and brain. (biomedcentral.com)
  • Au-Gold is found in igneous and sedimentary rocks at 0.004 ppm, fresh water at 0.00006 ppm, sea water at 0.000011 ppm, marine plants at 0.012 ppm, land plants 0.0005 to 0.002 ppm, marine animals at 0.0003 to 0.008 ppm, land animals at 0.00023 ppm, and in mammalian liver forms, as a colloid. (mighty-90.com)
  • These effects of honey have been thoroughly investigated in certain cancers such as breast, liver and colorectal cancer cell lines. (mdpi.com)
  • RON is activated in response to macrophage-stimulating protein (MSP), and then induces an invasive program ( 8 ) consisting of cell proliferation, migration, and invasion, all of which are important at multiple points during tumorigenesis. (spandidos-publications.com)
  • Hepatocyte growth factor (HGF) is produced by stromal and mesenchymal cells, and it stimulates epithelial cell proliferation, motility, morphogenesis and angiogenesis in various organs via tyrosine phosphorylation of its cognate receptor, Met. (spandidos-publications.com)
  • Studies from a number of laboratories in the past decade have revealed that the central pathways deregulated in cancer often serve to coordinately regulate both classic oncogenic signaling pathways controlling cell proliferation and cell survival with pathways controlling cell metabolism. (aacrjournals.org)
  • Augments the ability of dendritic cells to stimulate naive T-cell proliferation. (cusabio.com)
  • In response to mito- pendence between the key mecha- gens, cell proliferation is triggered by nistic characteristics. (who.int)
  • H - Ras cell proliferation are also linked with haematopoietic cel s. (who.int)
  • This collaboration between the Center for Epigenomics and Drs. Sander and Gaulton fills this knowledge gap by applying novel single cell technologies to characterize the transcriptional and epigenetic profiles of individual disease-relevant cells in the pancreas of nondiabetic and T1D donors. (ucsd.edu)
  • Endocrine Pancreas [1] "The transcription factor Pax6 functions in the specification and maintenance of the differentiated cell lineages in the endocrine pancreas. (edu.au)
  • The reproductive systems of mammalian males contain a component called the epididymis. (microscopyu.com)
  • The estrous cycle comprises the recurring physiologic changes that are induced by reproductive hormones in most mammalian placental females. (absoluteastronomy.com)
  • Expression of AND-34 regulates epithelial cell growth pattern, motility, and growth factor dependence. (molvis.org)
  • The conversion of an epithelial cell to a mesenchymal cell is critical to metazoan embryogenesis and a defining structural feature of organ development. (rupress.org)
  • The colon extends from the small intestine to the anal opening and is about five feet long in a human adult. (microscopyu.com)
  • We sought to establish the effects of the loss of AND-34 expression in a mammalian organism. (molvis.org)
  • Though smaller and less complex than that of humans, the rat brain is extremely useful as a subject of study because most regions of the brain are essentially the same among mammalian species. (microscopyu.com)
  • I've been working with mammalian embryos for over 40 years, with some work in my lab specifically focusing on various methods of cloning cattle and other livestock species. (wptv.com)
  • it's highly variable, though, depending on the cell type used and the species. (wptv.com)
  • After an incubation period of about 3-7 days, they cause the symptoms of a mild common cold/bronchitis (nasal obstruction, sneezing, runny nose, cough, headache, fever, pneumonia, asthenia, and inflammation in the airway) in avian and mammalian species. (scitcentral.com)
  • Vimentin is a developmentally regulated intermediate filament protein (IFP) found in cells of mesenchymal origin. (thermofisher.com)
  • Current interest in this process, which is described as an epithelial-mesenchymal transition (EMT), stems from its developmental importance and its involvement in several adult pathologies. (rupress.org)
  • In contrast, Dolly was produced by what's called somatic cell nuclear transfer. (wptv.com)
  • Small amounts of carbohydrates also occur in cell membranes, but, in contrast to plants and many invertebrate animals, humans have little structural carbohydrate in their bodies. (rincondelvago.com)
  • New disease data can be mapped onto the HLCA, transforming research in lung biology and disease. (rna-seqblog.com)
  • As the first whole reference atlas of a major organ, the HLCA also represents a milestone toward achieving a full Human Cell Atlas, which will transform our understanding of biology and disease and lay the foundation for a new era of health care. (rna-seqblog.com)
  • This atlas spans more than 2.4 million cells from 486 individuals and gives new insights into lung biology that were not possible before. (rna-seqblog.com)
  • 4 ] in 1951 cell culturing has become one of the most widely used methods with exceptional contribution to the advances in almost all fields of contemporary biology - cell biology, genetics, cell biochemistry, physiology etc. (intechopen.com)
  • Also covered in detail was the basic cell biology of EMT and its role in cancer and fibrosis, as well as the identification of new markers to facilitate the observation of EMT in vivo. (rupress.org)
  • Cold Spring Harbor, NY -- Cold Spring Harbor Laboratory Press (CSHLP) announced the release of The Digital Cell: Cell Biology as a Data Science, available on its website in hardcover format. (cshlpress.com)
  • Reuben J. Shaw, Howard Hughes Medical Institute, Molecular and Cell Biology Laboratory, The Salk Institute for Biological Studies, 10010 N. Torrey Pines Road, La Jolla, CA 92037. (aacrjournals.org)
  • Examples of a novel series of phenanthrolinones are shown to be potent competitive inhibitors of avian prolyl 4-hydroxylase, and of collagen hydroxylation, in embryonic chick tendon cells and human foreskin fibroblasts in vitro and in the oestradiol-stimulated rat uterus in vivo. (embl.de)
  • In embryonic avian tendon, cell density regulates collagen production. (embl.de)
  • Western blot analysis showed that stromal cells of lung tumours were characterised by a statistically considerably lower phrase level of the p16 proteins as likened with that in regular lung stromal cells. (immune-source.com)
  • G protein-coupled receptors , also known as seven-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein-linked receptors , comprise a large protein family of transmembrane receptors that sense molecules outside the cell and activate inside signal. (absoluteastronomy.com)
  • Hormones are recognised by either cell surface receptors (modified amino acids, peptides, proteins) or cytoplasmic/nuclear receptors (steroids). (edu.au)
  • The main artery of the mammalian circulatory system, the aorta is supplies oxygenated blood to the other arteries of the body. (microscopyu.com)
  • Maturation occurs in the cell membrane resulting in a 180-kDa heterodimeric protein composed of a 40-kDa α-chain and a 150-kDa transmembrane β-chain with intrinsic tyrosine kinase activity ( 5 , 6 ). (spandidos-publications.com)
  • Phospholipids and the steroid compound cholesterol are major components of the membrane that surrounds each cell. (rincondelvago.com)
  • Like lipids, proteins are an important constituent of the cell membrane. (rincondelvago.com)
  • all cells come in contact with the basement membrane (like alligator teeth). (freezingblue.com)
  • The cell membrane or plasma membrane is a biological membrane that separates the interior of all cells from the outside environment. (absoluteastronomy.com)
  • The cell membrane is selectively permeable to ions and organic molecules and controls the movement of substances in and out of cells. (absoluteastronomy.com)
  • These include regulation of cell cycle, activation of mitochondrial pathway, induction of mitochondrial outer membrane permeabilization, induction of apoptosis, modulation of oxidative stress, amelioration of inflammation, modulation of insulin signaling and inhibition of angiogenesis. (mdpi.com)
  • The results demonstrate that the membrane-bound form of RANKL is sufficient for most functions of this protein but that the soluble form does contribute to physiological bone remodeling in adult mice. (cusabio.com)
  • We find that U87 mg electrotaxis is abolished under pharmacological inhibition of PI3Kγ, mTOR, AKT and ErbB2 signaling, whereas DAOY cell electrotaxis was not attenuated by these or other pathways evaluated. (nature.com)
  • These studies have served to highlight the role of AND-34/BCAR3 and p130Cas in cell adhesion and migration signaling pathways. (molvis.org)
  • Induces osteoclastogenesis by activating multiple signaling pathways in osteoclast precursor cells, chief among which is induction of long lasting oscillations in the intracellular concentration of Ca (2+) resulting in the activation of NFATC1, which translocates to the nucleus and induces osteoclast-specific gene transcription to allow differentiation of osteoclasts. (cusabio.com)
  • We show that MDCK cells silenced for the polarity gene scribble ( scrib KD ) are hypersensitive to compaction, that interaction with wild-type cells causes their compaction and that crowding is sufficient for scrib KD cell elimination. (nature.com)
  • Cell type-specific and spatially resolved gene expression patterns are largely driven by cis-regulatory regions in the genome including promoters and distal acting enhancers. (ucsd.edu)
  • Thus, identifying and characterizing these elements by single cell DNA methylome and chromatin accessibility analysis is crucial to our understanding of gene regulation in the brain. (ucsd.edu)
  • However, there is limited knowledge of the molecular mechanism and gene regulatory networks underlying cardiac disease and a lack of cell-type specific annotation of risk variants associated with cardiovascular diseases. (ucsd.edu)
  • To fill in this gap, this project employs single nucleus ATAC-seq to elucidate cardiac cell type-specific gene regulatory elements in more than 200,000 nuclei isolated from adult human hearts. (ucsd.edu)
  • However, unlike other oncogenic retroviruses, deltaretroviruses have an additional region, tax (trans-activating region of the X gene), which has regulatory functions and is oncogenic to host cells. (cdc.gov)
  • Loss of expression is rarely due to deletion, mutation, or rearrangement of the MGMT gene, but methylation of discrete regions of the CpG island of MGMT has been associated with the silencing of the gene in cell lines. (aacrjournals.org)
  • For information on therapeutic regulation of gene expression, see therapeutic gene modulation.Regulation of gene expression includes the processes that cells and viruses use to regulate the way that the information in genes is turned into gene products. (absoluteastronomy.com)
  • Regarding the central nervous system (CNS), it has been shown that the C/EBPβ gene is expressed in different areas of adult rodents [ 9 ] and different studies, including those from our group, have indicated that C/EBPβ can have important functions in the brain. (biomedcentral.com)
  • We demonstrate here that loss of the primary cilium on postnatal biliary epithelial cells (via the deletion of the cilia gene Wdr35) drives ongoing pathological remodeling of the biliary tree, resulting in progressive cyst formation and growth. (bvsalud.org)
  • Cell density regulates prolyl 4-hydroxylase activity independent of mRNA levels. (embl.de)
  • More recently we have demonstrated that C/EBPβ regulates the expression of several genes involved in inflammatory processes and brain injury [ 14 ] and mice lacking C/EBPβ showed a reduced inflammatory response after kainic acid injection and exhibited a dramatic reduction in pyramidal cell loss in the CA1 and CA3 subfields of the hippocampus [ 15 ]. (biomedcentral.com)
  • We show that pharmacological inhibition of FKBP8 phenocopies dynein motor instability associated with the loss of ZMYND10 in airway cells and that human disease-causing variants of ZMYND10 disrupt its ability to act as an FKBP8-HSP90 co-chaperone. (bvsalud.org)
  • Northwestern Medicine scientists helped develop the largest and most comprehensive cell map of the human lung in a study that will be published June 8 in Nature Medicine. (rna-seqblog.com)
  • Revealing the great diversity of cell types in the lung and key differences between health and disease, the Human Lung Cell Atlas (HLCA) will be an important new resource for lung researchers. (rna-seqblog.com)
  • The Human Lung Cell Atlas is a huge resource for the scientific and medical community," said Dr. Alexander Misharin, a senior author on the paper and associate professor of medicine in pulmonary and critical care at Northwestern. (rna-seqblog.com)
  • By pooling and integrating datasets from every major single-cell RNA-sequencing lung study published to date, the team created the first integrated Human Lung Cell Atlas. (rna-seqblog.com)
  • The human lung is composed of a ramifying network of airways and blood vessels that connect millions of alveoli to the aerosol environment. (ucsd.edu)
  • Dolly was the culmination of hundreds of cloning experiments that, for example, showed diploid embryonic and fetal cells could be parents of offspring. (wptv.com)
  • Given the lack of access, and the dispersed nature of brain tumor cells, we explore the possibility of electric fields inducing directed tumor cell migration. (nature.com)
  • Among these is the isolation of the first line of murine stem cells [ 5 , 6 ] in 1981, followed by establishment of the first human embryonic stem cell lines by Thompson [ 7 ]. (intechopen.com)
  • Adult and embryonic Brugia malayi are shown to be susceptible to inhibitors of vertebrate prolyl 4-hydroxylase, with exposed parasites exhibiting pathologies consistent with a disruption in cuticle biosynthesis. (embl.de)
  • The strain is now valued as a source of embryonic stem cells for making knockout mice. (jax.org)
  • This control is propagated through the alpha-subunit of prolyl 4-hydroxylase where protein levels were previously shown to rise fivefold with increasing cell density. (embl.de)
  • Using a fluorescent sulfhydryl probe as well as a sulfhydryl inhibitor, one observes a strong cell density response, supporting the hypothesis that cellular redox potential could alter protein stability. (embl.de)
  • Western blot analysis and in situ hybridization confirmed the presence of AND-34 RNA and protein in lens epithelial cells, particularly at the lens equator. (molvis.org)
  • Our study indicates that primary ciliary dyskinesia (PCD), caused by mutations in dynein assembly factors disrupting cytoplasmic pre-assembly of axonemal dynein motors, should be considered a cell-type specific protein-misfolding disease. (bvsalud.org)
  • The Refametinib ending changed necessary protein typically additionally absence regular efficiency but, they constitute neo-epitopes, when provided in the circumstance of MHC elements at the growth cells' surface area. (immune-source.com)
  • DeMarini, and Chapter 20, by Rice and cell death determine the size protein in several signal ing path- and Herceg). (who.int)
  • How cells compete is poorly understood, but it is generally accepted that molecular exchange between cells signals elimination of unfit cells. (nature.com)
  • Here we show that scrib KD cells are out-competed by wild-type cells through mechanical insults rather than molecular exchange. (nature.com)
  • however, there is limited knowledge of the molecular blueprint that initiates and drives immune-mediated beta cell destruction. (ucsd.edu)
  • We are generating single cell maps of these niches using single nuclei ATAC-seq and RNA-seq to unravel the molecular mechanisms underlying niche diversity and interplay. (ucsd.edu)
  • In this study we investigate the properties of populations of brain cancer undergoing electrotaxis, a phenomenon whereby cells are directed to migrate under control of an electrical field. (nature.com)
  • Persons with the most common pediatric brain malignancy, medulloblastoma, fare only slightly better than average, with a 71.9% 5-year survival, though the most common adult brain tumor, glioblastoma multiforme (GBM), incurs a mere 5.1% 5-year survival rate 2 . (nature.com)
  • The mammalian brain comprises thousands of distinct cell types and is highly spatially organized to properly execute its diverse functions. (ucsd.edu)
  • Professor Owen, relying chiefly on the structure of the brain, has divided the mammalian series into four sub-classes. (literature.org)
  • However, the mechanisms by which scrib KD cells are killed by wild-type cells are largely unknown. (nature.com)
  • We therefore took advantage of this recent observation to investigate the mechanisms of cell competition. (nature.com)
  • To investigate the mechanisms of scrib KD -mediated cell competition, we first asked whether it is mediated by soluble factors, as in other cases of in vitro cell competition 6 , 24 . (nature.com)
  • This simplified approach towards understanding the essence of the mechanisms, underlying the processes determining life and death of a cell has undoubtedly provided scientists with enormous amount of knowledge. (intechopen.com)
  • C9orf43 expression varies in megakaryocyte differentiation as seen in peripheral blood CD34 plus cells as compared to CHRF-288-11 cells. (wikipedia.org)
  • The phenotype of Pax6-/- knockout mice suggests non-redundant functions of the transcription factor in the development of glucagon-expressing alpha-cells as this cell type is absent in the mutants. (edu.au)
  • When the one-cell embryo duplicates its genetic material, both cells of the now two-cell embryo are genetically identical. (wptv.com)
  • When they in turn duplicate their genetic material, each cell at the four-cell stage is genetically identical. (wptv.com)
  • This pattern goes on so that each of the trillions of cells in an adult is genetically exactly the same - whether it's in a lung or a bone or the blood. (wptv.com)
  • George D. Snell of The Jackson Laboratory won the 1980 Nobel Prize in Physiology or Medicine for "discoveries concerning genetically determined structures on the cell surface that regulate immunological reactions. (jax.org)
  • A defined synthetic mixture of amino acids, salts, carbohydrates, vitamins and serum was shown to support cells in vitro[ 3 ], thus unifying a major variable in cell culturing experiments and providing a possibility for rapid development of this novel method. (intechopen.com)
  • HGF was cloned as a growth factor for hepatocytes ( 1 , 2 ), is identical to scatter factor (SF) and was originally discovered as a fibroblast-derived cell motility factor for epithelial cells ( 3 ). (spandidos-publications.com)
  • The Misharin laboratory also provided biological expertise, which was essential for making this integrated lung cell atlas interpretable, actionable and relevant to lung diseases. (rna-seqblog.com)
  • The team is part of the Human Cell Atlas Lung Biological Network , which has its roots in the Chan Zuckerberg Initiative Seed Networks for the Human Cell Atlas and the European Union-funded lung network DiscovAIR . (rna-seqblog.com)
  • Alternative sites for cell density regulation of the enzyme could rely on its sensitivity to sulfhydryl groups. (embl.de)
  • May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. (cusabio.com)
  • Antitumor activity of NVP-BKM120- a selective pan class 1 PI3 Kinase inhibitor showed differential forms of cell death based on P53 status of glioma cells. (mdanderson.org)
  • By combining data from nearly 40 studies, researchers from the Wellcome Sanger Institute , Northwestern University Feinberg School of Medicine , Helmholtz Munich , University Medical Center Groningen and their collaborators created the first integrated single-cell atlas of the lung, revealing rare cell types and highlighting cellular differences between healthy people. (rna-seqblog.com)
  • To further understand electrotactic migration of tumor cells, we performed RNA-sequencing for pathway discovery to identify signaling that is differentially affected by the exposure of direct-current electrical fields. (nature.com)
  • In latest years, our group was leading in showing the high immunogenicity of MSI-induced frameshift-peptides (FSP) by determining many epitopes regarded by Testosterone levels cells [7]C[10]. (immune-source.com)
  • Using the traditional reverse-immunology strategy, Testosterone levels cells from healthful HLA-A0201+ contributor are triggered by artificial FSPs. (immune-source.com)
  • This remark is certainly a stunning point in favor of a significant Refametinib contribution to growth development control by FSP-specific Testosterone levels cells in vivo , producing those peptides extremely interesting applicants for the advancement of targeted vaccination strategies. (immune-source.com)
  • The study is part of the global Human Cell Atlas (HCA), an international collaborative consortium that is creating comprehensive reference maps of all human cells - the fundamental units of life - as a basis for understanding human health and for diagnosing, monitoring and treating disease. (rna-seqblog.com)
  • Emerging evidence shows that seamless collaboration between these specialized niches is fundamental for lung function and these niches are often sites of pathogenesis. (ucsd.edu)
  • Dr. Otto Warburg first described, more than 80 years ago, that a fundamental biochemical difference between tumor cells and their normal counterparts was that tumor cells rely on aerobic glycolysis for ATP generation, unlike most normal differentiated cells of the body, which use mitochondrial oxidative phosphorylation. (aacrjournals.org)
  • It's been 20 years since scientists in Scotland told the world about Dolly the sheep , the first mammal successfully cloned from an adult body cell. (wptv.com)
  • More than 10 different cell types have been used successfully as "parents" for cloning. (wptv.com)
  • To develop the HLCA, a large team of researchers successfully combined 49 lung datasets from nearly 40 separate studies into a single integrated atlas using advanced machine learning. (rna-seqblog.com)
  • Current knowledge of cellular behavior is mainly acquired by studies concerning homogenous populations of cells cultured as monolayers. (intechopen.com)
  • Weaved into this vast organ are exquisite regional differences in the form of cellular niches best defined at single-cell resolution. (ucsd.edu)
  • Water is found in the extracellular fluids of the body (the blood plasma, the lymph, and the interstitial fluid) and within the cells themselves. (rincondelvago.com)
  • Interestingly, we found that the growth rate of scrib KD cells is not affected by conditioned medium from competing cultures ( Fig. 1b and Supplementary Fig. 1c ). (nature.com)
  • In addition, the study found common cell states between lung fibrosis, cancer and COVID-19, offering new ways of understanding lung disease, which could help identify new therapeutic targets. (rna-seqblog.com)
  • In mammals, the highest levels are found in the hair and lungs. (mighty-90.com)
  • It is found in fresh water and sea water at 0.06 ppm and mammalian blood at 0.75 ppm. (mighty-90.com)
  • Alpha-gal syndrome (AGS) is an emerging, tick bite-associated immunoglobulin E-mediated allergic condition characterized by a reaction to the oligosaccharide galactose-alpha-1,3-galactose (alpha-gal), which is found in mammalian meat and products derived from mammals, including milk, other dairy products, and some pharmaceutical products. (cdc.gov)
  • Alpha-gal syndrome (AGS) is an emerging, tick bite-associated allergic condition characterized by a potentially life-threatening immunoglobulin E (IgE)-mediated hypersensitivity to galactose-alpha-1,3-galactose (alpha-gal), an oligosaccharide found in most nonprimate mammalian meat and products derived from these mammals. (cdc.gov)
  • It increases natural killer cell activity and decreases markers of inflammation. (scitcentral.com)
  • Expressed sequence tag (EST) analysis and developmental polymerase chain reaction (PCR) studies demonstrated that Ov-phy-1 was expressed in L3 and adult parasites. (embl.de)