• Subway trains produce airborne dust particles that could damage the lungs of commuters, scientists in France are reporting in a study of the Paris subway system scheduled for the October issue of ACS' Chemical Research in Toxicology . (phys.org)
  • Subway dust contained large amounts of iron particles and very low levels of endotoxin, a potentially toxic compound produced by bacteria. (phys.org)
  • Cohen says that up to now there has been indirect evidence of the link, but his study went further - testing lung tissue samples for the concentration of silica particles. (wgbh.org)
  • As the mining machines operate, the quartz in the sandstone turns into sharp silica particles that are easily inhaled and can lodge in the lungs permanently. (wgbh.org)
  • All four of those choices will filter dust particles well, but I do have some thoughts. (sawmillcreek.org)
  • We've covered before the dangers of dust in space but we can't forget the dangers of sand, pollution and airborne particles on earth. (lung.org)
  • Whether living in a desert environment, trapped in a sand storm or working in a coal mine, dusty environments expose the respiratory system to particles (sand, dust, etc. (lung.org)
  • Very fine particles can cause serious health issues like silicosis , or scarring of the lungs caused by silica, a mineral found in sand and rock. (lung.org)
  • The airborne particles carry microbes and fungi, and can react with human lung tissue. (jstor.org)
  • The last thing humankind needs is the microbe-laden dust particles waging yet another attack on their respiratory systems. (jstor.org)
  • 1993. Lung Dosimetry: Pulmonary Clearance of Inhaled Particles. (cdc.gov)
  • 1990. Clearance and retention of inhaled diesel exhaust particles, carbon black, and titanium dioxide in rats at lung overload conditions. (cdc.gov)
  • However, very little is known about the mechanism dust particles have on pulmonary function. (emerging-researchers.org)
  • We hypothesized that dust particles exert their effects by activating not only the pro-inflammatory signaling pathways but might also have an effect on the activation of development of genes important in altering DNA damage within cells. (emerging-researchers.org)
  • Dust is made of fine particles of solid matter. (wikipedia.org)
  • Road dust consists of deposits of vehicle and industrial exhaust gas, particles from tire and brake wear, dust from paved roads or potholes, and dust from construction sites. (wikipedia.org)
  • However, some small particles may remain trapped in your lungs for long periods, especially if exposure is frequent or prolonged. (websplashers.com)
  • In the present study, we explored dust particles PM modulated intracellular Ca2+ signaling and sought to provide a therapeutic strategy by antagonizing PM-induced intracellular Ca2+ signaling in human lung fibroblasts MRC5 cells. (yonsei.ac.kr)
  • A display case at NIOSH shows a normal lung and a diseased black lung, caused by inhaling coal dust and other harmful particles while coal mining. (npr.org)
  • Respirable crystalline silica ('RCS') is very small particles of silica (dust) created by high-energy processes like cutting, sawing, grinding, drilling, blasting, polishing and crushing of silica-containing materials. (mauriceblackburn.com.au)
  • The National Institute for Occupational Safety and Health (NIOSH), Coal Workers' Health Surveillance Program (CWHSP) studies the causes and effects of respiratory diseases related to coal mine dust exposure and provides vital health information to coal miners through health screenings and surveillance. (cdc.gov)
  • Exposure to dust in coal mines can cause community and mine locations to provide health screenings several lung diseases. (cdc.gov)
  • Interstitial lung diseases (ILDs) in childhood are a diverse group of conditions that primarily involve the alveoli and perialveolar tissues, leading to derangement of gas exchange and diffuse infiltrates on radiographs. (medscape.com)
  • Occupational lung diseases are a major work health and safety concern in Australia. (safeworkaustralia.gov.au)
  • This method involves changing different positions to ensure the mucus is completely drained from the lungs and is used to treat various diseases, such as bronchiectasis. (lunginstitute.com)
  • Here, we suggest functional inhibition of TRPM2 channels as a potential therapeutic strategy for modulation of dust particle-mediated signaling and oxidative stress accompanying lung diseases. (yonsei.ac.kr)
  • Occupational lung diseases are work-related lung conditions of the respiratory system. (safeworkaustralia.gov.au)
  • Occupational lung diseases include a broad range of lung diseases that may be acute, sub-acute or chronic, and either malignant, non-malignant, or infectious in nature. (safeworkaustralia.gov.au)
  • Safe Work Australia has developed a work plan for occupational lung diseases. (safeworkaustralia.gov.au)
  • Duty holders, particularly in small to medium enterprise, are often don't know their WHS duties and how they must protect their workers from dusts that can cause occupational lung diseases. (safeworkaustralia.gov.au)
  • Improve compliance with WHS laws and improve the health and safety of workers, resulting in less workers being diagnosed with occupational lung diseases. (safeworkaustralia.gov.au)
  • h2>What diseases can be caused by silica dust exposure? (mauriceblackburn.com.au)
  • Infections, inflammatory diseases, and other factors such as the following are associated with lung granulomas. (healthline.com)
  • Lung granulomas are associated with some common variable immunodeficiency disorders (CVID) that prevent your body from fighting infections and diseases. (healthline.com)
  • The pneumoconioses, extrinsic allergic alveolitis, lung damage due to irritant gases, fumes, and smoke constitute the occupational lung diseases that affect the lung parenchyma. (nih.gov)
  • The pneumoconioses are diseases resulting from the accumulation of dust in the lungs. (nih.gov)
  • Eggshell calcification may occur in lymph nodes, and eventually the diseases may be complicated by the development of large massive areas of fibrosis in the upper lung zones. (nih.gov)
  • Introduction: Chronic respiratory diseases (CRDs) are diseases of the airways and lung parenchyma. (who.int)
  • This study aimed to characterize the common chronic respiratory diseases, along with their lung function and possible determinants in symptomatic patients attending clinics at Bishoftu General Hospital, Ethiopia. (who.int)
  • Chronic respiratory diseases (CRDs) are diseases of such as age above 50years, being a smoker, being the respiratory airways and lung parenchyma. (who.int)
  • Exposure to the subway dust triggered transient lung inflammation in the mice and increased levels of several substances produced by the immune system that might cause tissue damage. (phys.org)
  • Still other microbes penetrate deep into people's airways and react with lung tissue. (jstor.org)
  • Silica dust comes from quartz in the rock layers near coal seams, and it is significantly more harmful to lung tissue than coal dust alone. (100daysinappalachia.com)
  • Smith's lungs are riddled with fibrotic tissue. (wqln.org)
  • Coughing violently, he spit out what looked like moist and crusty bits of dark gray paper with black streaks - dead lung tissue, his respiratory therapist told us. (wqln.org)
  • The middle slide depicts a lung with fibrotic tissue resulting from simple coal workers' pneumoconiosis or black lung. (npr.org)
  • The slide on the right shows hardened and blackened lung tissue when black lung disease reaches its most advanced stage. (npr.org)
  • Tiny specks of coal and rock dust get lodged in the lungs and cause scarring, which prevents lung tissue from absorbing oxygen. (dailyyonder.com)
  • When lung tissue becomes inflamed from an infection or other cause, cells called histiocytes cluster to form nodules called granulomas. (healthline.com)
  • NPR and Frontline found thousands of recent cases of the severe disease, known as complicated black lung or progressive massive fibrosis, in just five Appalachian states. (wgbh.org)
  • Central Appalachia has seen a marked increase in the most severe form of black lung, known as progressive massive fibrosis. (100daysinappalachia.com)
  • Eleven years ago, at the age of 57, Johnson was diagnosed with progressive massive fibrosis, the most severe stage of black lung disease. (mountainstatespotlight.org)
  • from 2019 to mid-2023, nearly 30% of Americans diagnosed with progressive massive fibrosis at federally-funded black lung clinics were West Virginians, according to the Black Lung Data and Resource Center at the University of Illinois Chicago . (mountainstatespotlight.org)
  • Smith suffers from progressive massive fibrosis, or complicated black lung, an advanced, incurable and fatal stage of black lung disease. (wqln.org)
  • Progressive massive fibrosis is an especially aggressive form, blamed on inhalation of silica dust from the cutting of quartz rock and coal together. (npr.org)
  • That brings the NPR count of progressive massive fibrosis, the most serious stage of the disease known as black lung, to nearly 2,000 cases in the region, all of which were diagnosed since 2010. (npr.org)
  • The study confirmed 416 cases of the most severe form of black lung disease, Progressive Massive Fibrosis. (dailyyonder.com)
  • It's important to identify if your work processes are creating hazards such as dusts, gases, fumes or vapours, that if inhaled can cause lung disease," said Safe Work Australia Chief Executive Officer Michelle Baxter. (safeworkaustralia.gov.au)
  • If a person is exposed to a hazard at their workplace, such as dusts, gases, fumes, vapours, mists or microorganisms they are at risk for developing a disease. (safeworkaustralia.gov.au)
  • Half of the patients (50.3%) were exposed daily to vapors, dust, gases, or fumes and 58 (34.3%) were exposed to biomass smoke. (who.int)
  • Exposure to other lung irritants-such as air pollution, chemical fumes, or dust-may contribute to COPD. (medlineplus.gov)
  • DNA damage is suggested to drive pathophysiological lung processes in infant lung, pulmonary hypertension, asthma and chronic obstructive pulmonary disease. (emerging-researchers.org)
  • Restrictive lung problems include extrapulmonary causes such as obesity, spine or chest wall deformities, and intrinsic pulmonary pathology such as interstitial fibrosis, pneumoconiosis, granulomatous disease or collagen vascular disease. (aafp.org)
  • The acute reaction may produce diffuse lung injury characterized by air-space disease typical of pulmonary edema. (nih.gov)
  • According to the 2002 American Thoracic Society (ATS)/European Respiratory Society (ERS) consensus statement, IPF is defined as a distinctive type of chronic fibrosing interstitial pneumonia of unknown cause limited to the lungs and with histologic features of UIP on surgical lung biopsy or certain clinical, radiologic, and pulmonary function test findings in the absence of surgical lung biopsy. (medscape.com)
  • Most patients display restrictive pulmonary function abnormalities, including reduced lung volumes with relative preservation of airflow, a reduction in the diffusion capacity for carbon monoxide (DLCO) with hypoxemia at rest and/or with exercise. (medscape.com)
  • Chronic obstructive pulmonary disease (COPD) is a serious lung disease that makes it hard to breathe. (medlineplus.gov)
  • However, antibiotics are sometimes necessary to treat your bronchitis if you already have another lung disease, such as chronic obstructive pulmonary disease, COPD. (folkhalsomyndigheten.se)
  • campaign aims to raise awareness of the dangers of occupational lung disease to protect workers from breathing in hazardous air. (safeworkaustralia.gov.au)
  • Occupational lung disease. (medlineplus.gov)
  • campaign is the key national education and awareness activities, focusing on micro and small to medium enterprises, to raise awareness of occupational lung disease and how it can be prevented. (safeworkaustralia.gov.au)
  • A new study provides the first evidence of its kind that silica dust is responsible for the rising tide of severe black lung disease, including among coal miners in Appalachia. (wgbh.org)
  • Exposure to a toxic rock dust appears to be "the main driving force" behind a recent epidemic of severe black lung disease among coal miners, according to the findings of a new study . (wgbh.org)
  • The study, which examined the lungs of modern miners and compared them to miners who worked decades ago, provides the first evidence of its kind that silica dust is responsible for the rising tide of advanced disease, including among miners in Appalachia. (wgbh.org)
  • Cohen's study specifically looked at contemporary miners with severe disease, and what was lodged in their lungs, compared to older workers who also had severe lung disease. (wgbh.org)
  • Among them were miners in their 30s who experienced a rapid progression to advanced lung disease. (wgbh.org)
  • Whether you are a patient living with lung disease or a caregiver, join the Patient & Caregiver Network for timely education, support and connection. (lung.org)
  • The work reveals that while attention has been trained on a surge in disease among underground coal miners, surface miners are similarly at risk of contracting coal worker's pneumoconiosis, or black lung disease. (100daysinappalachia.com)
  • Black lung disease has been identified in coal miners in every coal-mining state at both surface and underground mines. (100daysinappalachia.com)
  • After decades of successful reduction in black lung disease through safety controls in coal mines, black lung disease has been on the rise among coal miners for the last two decades. (100daysinappalachia.com)
  • A recent investigation from NPR and PBS Frontline found that federal regulators and the mining industry knew that exposure to silica dust was a major factor contributing to the surge in disease but failed to act to protect miners' health. (100daysinappalachia.com)
  • The surge in disease is putting strain on the already-indebted federal Black Lung Disability Trust Fund , and as younger miners become disabled due to black lung, the strain on Appalachian mining communities continues to grow. (100daysinappalachia.com)
  • Since a mixture of nonsiliceous minerals and/or black pigment is often seen in association with classical silicosis, the determinants for the development of mixed-dust fibrotic nodules are somewhat uncertain [Silicosis and Silicate Disease Committee 1988]. (cdc.gov)
  • Because ILDs can involve the distal airspaces as well as the interstitium, the terms diffuse lung disease or diffuse infiltrative lung disease have been suggested. (medscape.com)
  • Although this nomenclature may be more accurate than ILD, childhood interstitial lung disease (chILD) has become the preferred term. (medscape.com)
  • Debbie Johnson, a nurse in Mercer County, talks about her husband Danny, a retired coal miner who has been diagnosed with silicosis and black lung disease. (mountainstatespotlight.org)
  • What disease can you get from inhaling construction dust? (dallamaids.com)
  • Byssinosis is a disease of the lungs. (medlineplus.gov)
  • Being exposed to the dust many times can lead to long-term (chronic) lung disease. (medlineplus.gov)
  • Continued exposure can lead to end-stage lung disease. (medlineplus.gov)
  • Smith, 51, suffers from an advanced and incurable stage of black lung disease. (wqln.org)
  • Danny Smith spent just 12 years mining coal before he was diagnosed with complicated black lung disease at 39. (wqln.org)
  • But if the rule is adopted, the agency predicts it would save only 63 coal miner lives and avoid 244 cases of black lung disease over 60 years. (wqln.org)
  • Coal dust is responsible for the respiratory disease known as pneumoconiosis, including coal worker's pneumoconiosis disease that occurs among coal miners. (wikipedia.org)
  • Sliced sections of lungs show the damage and disease caused by excessive exposure to coal and silica dust. (npr.org)
  • NPR's ongoing investigation of the advanced stage of the fatal lung disease that afflicts coal miners has identified an additional 1,000 cases in Appalachia. (npr.org)
  • that definitively demonstrates that we are in the midst of an epidemic of black lung disease in central Appalachia," Laney said Thursday in Morgantown, W.Va., during a presentation before a National Academy of Sciences committee investigating efforts to control the coal mine dust that causes the disease. (npr.org)
  • A 44-yr-old male presented with shortness of breath, diffuse X-ray infiltrates, and physiologic evidence of a restrictive lung disease. (nih.gov)
  • Organic dust exposure in agricultural environments results in an inflammatory response that attenuates over time, but repetitive exposures can result in chronic respiratory disease. (nebraska.edu)
  • Danger Contains Asbestos Fibers Avoid Creating Dust Cancer And Lung Disease Hazard For More Information Contact: Name:____ Address: _____ City: _____ State: __ Zip:_____ For More Information Read Msds! (firstaidandsafetyonline.com)
  • Pneumoconiosis is lung disease that is caused by breathing in certain types of dust. (safeworkaustralia.gov.au)
  • Coal workers' pneumoconiosis, commonly known as Black Lung disease, is reaching epidemic levels in the central Appalachian coalfields. (dailyyonder.com)
  • The central Appalachian coalfields are in the middle of an unprecedented epidemic of severe black lung disease. (dailyyonder.com)
  • What is black lung disease and why is it resurging? (dailyyonder.com)
  • Some young miners have contracted severe black lung disease after just eight years working in mines. (dailyyonder.com)
  • In reporting on this epidemic, the ReSource and NPR have interviewed dozens of Appalachian miners who are struggling with severe black lung disease, including Jerry Helton and Edward Brown. (dailyyonder.com)
  • Both men contracted severe black lung disease from working in mines around the same area, but they've been left in very different situations, due to differences in the benefits and medical care they've received. (dailyyonder.com)
  • The dirty disease' - both smokers and non-smokers get lung cancer. (theconversation.com)
  • nbsp;This theme asks us is to consider potential workplace hazards that cause injury and disease, and the ways in which these risks can either be eliminated, or at least minimised, by establishing proper workplace exposure standards for WA workers who frequently are working with silica dust. (mauriceblackburn.com.au)
  • When this inflammatory disease affects the lungs, symptoms may include a dry cough, shortness of breath, and wheezing. (healthline.com)
  • If this bacterial disease is in the lungs, symptoms may include a chronic cough, coughing up blood or phlegm, and chest pain. (healthline.com)
  • The ILO has established a standardized system for classification of these pneumoconioses that includes both descriptions of diffuse lung opacities and pleural disease. (nih.gov)
  • Berylliosis is a systemic disorder that in its chronic form produces granulomatous disease in the lungs. (nih.gov)
  • The reported overall prevalence of interstitial lung disease in New Mexico is 80.9 per 100,000 males and 67.2 per 100,000 females, corresponding with annual incidence rates of 31.5 per 100,000 per year in males and 26.1 per 100,000 per year in females. (medscape.com)
  • Several associations have been identified, including cigarette smoking, gastroesophageal reflux disease, occupational exposure to wood and various other occupation-related dusts, Epstein-Barr virus, and hepatitis C virus. (medscape.com)
  • Inhalation pare the effect of acute exposure to pesti- of pesticide dust, vapours, mists and gases cides of these workers with a group of may therefore represent a significant occu- workers not occupationally exposed to pational hazard [ 6 ] with workers vulnerable pesticides. (who.int)
  • The stellate nodule, as opposed to the more classical rounded silicotic nodule, has irregular extensions into the adjacent lung parenchyma, producing a "Medusa-head" lesion ( Fig. 21 ). (cdc.gov)
  • The rate and pattern of breathing are also influenced by signals from neural receptors in the lung parenchyma, large and small airways, respiratory muscles and chest wall. (aafp.org)
  • The former two entities are characterized radiographically by the presence of small rounded opacities or nodules in the lung parenchyma. (nih.gov)
  • And this summer, the federal Mine Safety and Health Administration (MSHA) finally issued a proposed new regulation to limit miners' silica dust exposure. (wqln.org)
  • The draft rule would establish a silica dust exposure limit twice as tough as it is now. (wqln.org)
  • Silica dust exposure from pitchblende processing was estimated (n = 1317). (bvsalud.org)
  • These techniques are more important, especially for those with lung health issues like COPD and chronic bronchitis . (lunginstitute.com)
  • It means that if you are suffering from COPD, your lungs will produce excess mucus, trapping a lot of dust. (lunginstitute.com)
  • Increasing age, exertional breathlessness, prior diagnosis of asthma, BMI, and clinically diagnosed COPD and asthma were independently associated with obstructed lung function. (who.int)
  • In people who have COPD, the airways-tubes that carry air in and out of your lungs-are partially blocked. (medlineplus.gov)
  • Inhalation of dust during cement production has been linked to airway symptoms and obstructive lung changes [ 4 , 5 ], but the lack of good prospective studies has made it difficult to establish exposure-response relationships [ 5 ]. (ersjournals.com)
  • You may notice that your symptoms become severe during the cold months if you have a lung problem. (lunginstitute.com)
  • Stopping exposure to the dust often improves symptoms. (medlineplus.gov)
  • If you have asthma or another respiratory condition, exposure to drywall dust can make your symptoms worse. (websplashers.com)
  • Long-term occupational exposure to cotton dust that contains endotoxin is associated with chronic respiratory symptoms and excessive decline in forced expiratory volume in 1 sec (FEV 1 ), but the mechanisms of endotoxin-related chronic airflow obstruction remain unclear. (nih.gov)
  • However, the long-term exposure-response relationship between endotoxin and change in lung function and respiratory symptoms is not well understood. (nih.gov)
  • Whether the excessive decline in lung function and the occurrence of respiratory symptoms are influenced differently by more recent or more remote exposure to endotoxin is unknown. (nih.gov)
  • New screening guidelines and recognizing early symptoms can help address the changing face of lung cancer. (theconversation.com)
  • While lung granulomas usually have no symptoms, their underlying cause may present symptoms. (healthline.com)
  • There are seldom symptoms associated with lung granulomas themselves. (healthline.com)
  • Lung granulomas with no abnormal symptoms may not need to be treated. (healthline.com)
  • Symptoms of this lung infection include fever, dry cough, chest pain, and red bumps on your lower legs. (healthline.com)
  • Additionally, indoor allergens such as dust mites, mold, and pet dander can exacerbate symptoms. (ncvc.org)
  • Conclusion: This study demonstrated a high burden of abnormal lung function in patients attending clinics due to chronic respiratory symptoms. (who.int)
  • 4 ings highlight the critical need for spirometry services to identify lung abnormalities in patients with chronic res- piratory symptoms. (who.int)
  • Exposure to silica dust likely explains Smith's complicated black lung diagnosis at the relatively young age of 39 and after just 12 years of cutting rock and coal underground. (wqln.org)
  • p>One of the most significant workplace hazards in Western Australia is exposure to silica dust, which affects many workplaces in the construction, mining, quarrying and manufacturing industries. (mauriceblackburn.com.au)
  • In some industrial settings, such as foundry work or coal mining, the inhalation of free crystalline silica in conjunction with other minerals leads to a characteristic stellate nodule of mixed-dust fibrosis. (cdc.gov)
  • Building on our previous research, the purpose of this project is to determine whether exposome-altered innate lung defense caused by organic dust inhalation negatively impacts susceptibility and pathogenesis of bacterial pneumonia, placing individuals with COVID-19 exposure, alcohol use disorders (AUD), or zinc deficiency particularly in harm's way. (unmc.edu)
  • It opens the airway and helps the lungs expel mucus by breathing in water vapor, which is known as steam treatment or steam inhalation. (dallamaids.com)
  • It's caused by the inhalation of coal mine dust, especially exposure to highly dangerous silica dust . (wqln.org)
  • Finally, hypersensitivity pneumonitis or extrinsic allergic alveolitis is a response of the lung to inhalation of antigens that may be present in the workplace. (nih.gov)
  • And while there hasn't been enough research on the subject, one study documented a 17-fold increase in asthma attacks in Barbados between 1973 and 1996, corresponding with the increase in the African dust transported to the region. (jstor.org)
  • Our results suggest that acute road dust exposure influences the expression of DNA repair genes in human lung cells and could activate asthma development in certain individuals. (emerging-researchers.org)
  • This study was conducted to evaluate the prevalence and risk factors for work-related respiratory conditions (asthma, farmer's lung, sinusitis, rhinitis, and environmental allergies, diagnosed by a physician) among farm and ranch operators in the central US. (cdc.gov)
  • Those who are sensitive to the dust can have an asthma-like condition after being exposed. (medlineplus.gov)
  • Bacteria-containing dust found at day care centers could put children at a higher risk of asthma , a new study from the European Respiratory Society suggests. (chronicleslive.com)
  • It entails coughing from deep in the lungs, thus building an adequate force to remove the mucus from the airways. (lunginstitute.com)
  • This is swelling (inflammation) of the large airways of the lungs with a large amount of phlegm production. (medlineplus.gov)
  • Drywall dust can irritate your airways and cause coughing, wheezing, and shortness of breath. (websplashers.com)
  • The irritation of the airways heals slowly, and this centre for a lung examination. (folkhalsomyndigheten.se)
  • We will also examine alterations in the metabolomic profile and correlate them to the changes in the immunometabolic function of alveolar and interstitial lung macrophages in this mouse model of WTC dust exposure. (cdc.gov)
  • Usual interstitial pneumonia (UIP) refers to a morphologic entity defined by a combination of (1) patchy interstitial fibrosis with alternating areas of normal lung, (2) temporal heterogeneity of fibrosis characterized by scattered fibroblastic foci in the background of dense acellular collagen, and (3) architectural alteration due to chronic scarring or honeycomb change. (medscape.com)
  • In this project, we are testing the hypothesis that chronic intermittent hypoxia exacerbates WTC dust exposure induced oxidative stress, lung injury, and alterations in lung function in a mouse model of WTC dust exposure. (cdc.gov)
  • Most forms of chILD require surgical lung biopsy for definitive diagnosis. (medscape.com)
  • What's more, the investigation found, federal regulators knew about excessive and toxic mine dust exposures but didn't act - retaining an old regulatory standard for mining dust that doesn't directly address silica. (wgbh.org)
  • Risk factors for respiratory conditions included exposures to grain/hay/feed dust (OR 2.41), animal confinement dust (OR 1.57), field/road dust (OR 2.11), manure/silage gasses (OR 1.66), anhydrous ammonia (OR 1.51), fuels/solvents/paints (OR 1.92), older age group >70 vs. (cdc.gov)
  • That trend is widely attributed to more frequent exposures to silica dust . (mountainstatespotlight.org)
  • Dust exposure resulted in increased bronchoalveolar lavage fluid neutrophils and macrophages after single and repetitive exposures. (nebraska.edu)
  • Lavage fluid TNFα, IL-6, keratinocyte chemoattractant, and macrophage inflammatory protein-2 were significantly increased after single and repetitive dust exposures, but were dampened in 2-wk dust-exposed mice compared with single exposure. (nebraska.edu)
  • Dust exposure induced PKCα and -ε activation in isolated tracheal epithelial cells but were dampened with repetitive exposures. (nebraska.edu)
  • Collectively, intranasal exposure to DE results in significant lung inflammatory and pathological responses marked by a modulated innate immune response to single and repetitive dust exposures that is associated with PKC activity. (nebraska.edu)
  • We hypothesised that exposure to workplace aerosols may lead to lung function impairment among cement production workers. (ersjournals.com)
  • This study investigated the effects of single vs. repetitive dust-induced airway inflammation in mice by intranasal exposure method. (nebraska.edu)
  • This is a rare but serious type of vasculitis , inflammation of the blood vessels in your nose, throat, lungs, and kidneys. (healthline.com)
  • Lung granulomas, also referred to as rheumatoid or lung nodules, occur in 20 percent of people with RA, a condition that causes joint pain and inflammation. (healthline.com)
  • Nolan's group has previously shown that markers for the metabolic syndrome, inflammation, and vascular injury detected in serum samples taken within 6 months of 9/11 were predictive for later abnormal lung function. (medscape.com)
  • 3-088- inflammation of the main passages of the lungs. (folkhalsomyndigheten.se)
  • Classification of lung function revealed 23 (15%) normal, 29 (19%) obstructive, 36(23.5%) restrictive and 61(39.9%) mixed obstructive/ restrictive patterns. (who.int)
  • Among their findings was that the more-contemporary workers - those born after 1930 - had more silica in their lungs than the miners who were born between 1910 and 1930. (wgbh.org)
  • These include black lung, to all coal miners (past and present). (cdc.gov)
  • Active coal miners can visit NIOSH-approved clinics to receive their free mandatory or voluntary black lung screenings. (cdc.gov)
  • Appalachian surface coal miners are consistently overexposed to toxic silica dust, according to new research from the National Institute for Occupational Safety and Health , and surface mine dust contains more silica than does dust in underground coal mines. (100daysinappalachia.com)
  • We know that silica and mine dust are toxic, and we have the technology to suppress it, and yet coal miners are still exposed to way too much of it. (100daysinappalachia.com)
  • 2001. A Biomathematical Model of Particle Clearance and Retention in the Lungs of Coal Miners I. Model Development. (cdc.gov)
  • For miners with black lung, the inaction has been deadly. (mountainstatespotlight.org)
  • As a black lung nurse at Bluestone Health Center in Kegley, she's used to seeing patients like Johnson - miners who get winded from walking up their front porch stairs, on a daily basis. (mountainstatespotlight.org)
  • Experts think this may be due to miners working longer hours and inhaling an especially toxic silica dust produced from cutting sandstone. (dailyyonder.com)
  • This airborne dust is considered an aerosol and once in the atmosphere, it can produce strong local radiative forcing. (wikipedia.org)
  • Advances in airborne dust control technologies and work processes may indicate that more innovative measures are available for dust control and mitigation. (safeworkaustralia.gov.au)
  • Danny Johnson, a retired coal miner who has been diagnosed with severe black lung, holds a protective mask that used to be white. (mountainstatespotlight.org)
  • According to the authors, it's the largest number of severe black lung cases ever documented, and one of the worst industrial epidemics in American history. (dailyyonder.com)
  • NPR contacted black lung clinics, physicians and attorneys across the country. (npr.org)
  • In a recent issue of the Journal of the American Medical Association federal researchers released the results of a study conducted at just three black lung clinics. (dailyyonder.com)
  • Future research involves the effects of house dust on reactive oxygen species generation and proinflammatory cellular pathways. (emerging-researchers.org)
  • It is caused by breathing in (inhaling) cotton dust or dusts from other vegetable fibers such as flax, hemp, or sisal while at work. (medlineplus.gov)
  • Moreover, the dust-which is rich in nutrients like iron-can feed the local bacteria, spiraling its population out of control. (jstor.org)
  • One of the marine bacteria that thrive on the iron-rich dust arriving in North America is Vibrio cholerae , which causes cholera. (jstor.org)
  • Abelowitz reiterated the need for more studies to explore these "complex communities of bacteria" and their potential association with long-term lung issues for children . (chronicleslive.com)
  • Phlegm and expectoration also serve as start to cough up blood or having difficulty breathing, a barrier that captures inhaled dust, bacteria and viruses. (folkhalsomyndigheten.se)
  • So, we might expect this exposure to have an impact on children's developing lungs via the different microbiota that arise in children's airway, gut or skin. (chronicleslive.com)
  • Airway hyperresponsiveness to methacholine occurred after single dust exposure but resolved after 2 wk. (nebraska.edu)
  • As such, one needs to learn practice-controlled coughing to cough effectively and release the dust in the lungs. (lunginstitute.com)
  • Cough medicines rarely have any effect when it comes throat to the lungs swell and become irritated. (folkhalsomyndigheten.se)
  • If you feel well except for a cough, you annoying at times, coughing is the body's way of protect- have no need to worry, particularly if you notice a gradual ing the lungs. (folkhalsomyndigheten.se)
  • The aim of this study is to determine the effect of house dust on viability, cytotoxicity and apoptosis in normal human bronchial epithelial cells (BEAS-2B). (emerging-researchers.org)
  • Workers in cement plants are exposed to airborne particulate matter (dust) generated from cement and raw materials during the production of cement. (ersjournals.com)
  • Senior author Anna Nolan, MD, whose lab members study predictors of lung function loss in a cohort of firefighters who were exposed to the particulate matter clouding the air of lower Manhattan on 9/11 and the ensuing days, told Medscape Medical News that the findings, while preliminary, support previous research findings on potential links between intestinal microbiota and lung function. (medscape.com)
  • Lung -inflammatory Reply to Ecological Airborne dirt and dust Direct exposure throughout Rodents Indicates one of the links to Regional The respiratory system Ailment Danger. (cyt387inhibitor.com)
  • Some of the issues include:[citation needed] Reducing dust related health risks that include allergic reactions, pneumonia and asthmatic attacks. (wikipedia.org)
  • Dynamic lung volumes were assessed by repeated spirometry testing during a mean follow-up time of 3.5 years (range 0.7-4.6 years). (ersjournals.com)
  • Spirometry is a test that evaluates how well your lungs work by measuring how much air you can inhale and exhale, and how quickly you exhale. (cdc.gov)
  • Lung function was measured by spirometry. (who.int)
  • The research is the first to specifically analyze long-term data on exposure to toxic silica dust for workers at surface mines. (100daysinappalachia.com)
  • Want updates on the latest lung health news, including COVID-19, research, inspiring stories and health information? (lung.org)
  • Black lung screenings are provided at NIOSH-approved clinics located in mining regions across the U.S. Find information about facilities on the NIOSH-Approved Facility Search and Map web page at wwwn.cdc.gov/niosh-rhd/cwhsp/FacilityMap.aspx. (cdc.gov)
  • Occupational exposure to organic dust increases lung cancer risk in the general population. (who.int)
  • Indoor dust in the house can be a significant pathway for human exposure to toxic contaminants. (emerging-researchers.org)
  • Samples of house dust were acquired by the National Institute of Standards and Technology (NIST, Gaithersburg, MD, USA), which are SRM 2584 (Trace Elements in Indoor Dust, 1% lead), and SRM 2585 (Organic Contaminants in House Dust). (emerging-researchers.org)
  • Learn how indoor air-borne contaminants end up in the lungs and body. (bioedonline.org)
  • To test this hypothesis, we examined hypoxic gene expression using real-time PCR in non-cancer lung cells exposed to Road dust and compared expression in lung cells grown under normal conditions with no road dust present. (emerging-researchers.org)
  • The effect of road dust induced DNA damage after 24 hours is comparatively higher in the expression of GADD45a, NTHL1 and APEX1 genes. (emerging-researchers.org)
  • I was tasked with culturing the cells and exposing the cells to road dust at various time points. (emerging-researchers.org)
  • Road dust is a significant contributor to the generation and release of particulates into the atmosphere. (wikipedia.org)
  • Control of road dust is a significant challenge in urban areas, and also in other locations with high levels of vehicular traffic upon unsealed roads, such as mines and landfills. (wikipedia.org)
  • Road dust may be suppressed by mechanical methods like street sweeper, vehicles equipped with vacuum cleaners, vegetable oil sprays, or with water sprayers. (wikipedia.org)
  • Controlled coughing is one of the ways you can expel dust that is trapped in the mucus. (lunginstitute.com)
  • Over time, ozone can cause permanent lung damage. (lung.ca)
  • 1993. Lung deposition, lung clearance and renal accumulation of inhaled cadmium chloride and cadmium sulphide in rats. (cdc.gov)
  • Nuclear microprobe investigation of red sludge dust deposition in rat lung. (atomki.hu)
  • This medical condition causes the lungs to produce excess mucus, thus leading to frequent coughing. (lunginstitute.com)
  • Breathe in again through the nose to ensure the mucus does not flow back to the lungs. (lunginstitute.com)
  • Postural drainage entails using gravity to drain mucus from the lungs. (lunginstitute.com)
  • Ultimately, irrespective of the position you use, you will drain out the mucus containing the dust you have inhaled. (lunginstitute.com)
  • This is because the cold air dries out the mucus in your lungs, making it difficult for it to come out. (lunginstitute.com)
  • However, steam therapy loosens the mucus in the lungs, making breathing easy. (lunginstitute.com)