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  • sarcoidosis
  • Sarcoidosis is a disease involving abnormal collections of inflammatory cells that form lumps known as granulomas. (wikipedia.org)
  • In 2015 pulmonary sarcoidosis and interstitial lung disease affected 1.9 million people globally and they resulted in 122,000 deaths. (wikipedia.org)
  • Sarcoidosis was first described in 1877 by the English doctor Jonathan Hutchinson as a non-painful skin disease. (wikipedia.org)
  • Sarcoidosis is a systemic inflammatory disease that can affect any organ, although it can be asymptomatic and is discovered by accident in about 5% of cases. (wikipedia.org)
  • Localization to the lungs is by far the most common manifestation of sarcoidosis. (wikipedia.org)
  • nodules
  • Alveolar disease is visible on chest radiography as small, ill-defined nodules of homogeneous density centered on the acini or bronchioles. (wikipedia.org)
  • The nodules coalesce early in the course of disease, such that the nodules may only be seen as soft fluffy edges in the periphery. (wikipedia.org)
  • Rheumatoid lung disease is characterized by pleural effusion, pulmonary fibrosis, lung nodules and pulmonary hypertension. (wikipedia.org)
  • 1954, rheumatoid lung nodules were found in patients with RA who were not exposed to coal dust and without pneumoconiosis. (wikipedia.org)
  • autoimmune
  • However, RF is also associated with other autoimmune diseases. (wikipedia.org)
  • Examples include autoimmune disorders, viral infections and bacterial infection like tuberculosis which may cause fibrotic changes in both lungs upper or lower lobes and other microscopic injuries to the lung. (wikipedia.org)
  • clinical
  • In Pulmonary Arterial Hypertension and Interstitial Lung Disease: A Clinical Guide, renowned experts provide a state-of-the-art overview of the problems seen by physicians in the clinical management of ILDs. (springer.com)
  • Approach to the adult with interstitial lung disease: Clinical evaluation. (mayoclinic.org)
  • Spiropoulos, K. (2008), "The alcoholic lung disease: historical background and clinical features", Medicina(Kaunas), 44 (9): 51-64, PMID 18971602 Pratibha C. Joshi, David M. Guidot (2007). (wikipedia.org)
  • Radiologic appearance alone however is not adequate and should be interpreted in the clinical context, keeping in mind the temporal profile of the disease process. (wikipedia.org)
  • Granulomatous disease in CVID: retrospective analysis of clinical characteristics and treatment efficacy in a cohort of 59 patients. (wikipedia.org)
  • Provides unparalleled depth and breadth of research and clinical expertise to diagnose and treat lung diseases. (dmoztools.net)
  • Article by Irfan Maghfoor, MD about the clinical and biologic characteristics of the disease. (dmoztools.net)
  • abnormal
  • It may occur when an injury to the lungs triggers an abnormal healing response. (wikipedia.org)
  • Multiple abnormal laboratory findings have been noted in indium lung. (wikipedia.org)
  • Other abnormal laboratory values that have been found include elevated alanine aminotransferase, elevated aspartate aminotransferase, elevated C-reactive protein, elevated interstitial lung disease markers, and elevated GM-CSF autoantibodies. (wikipedia.org)
  • tuberculosis
  • Smriti Mehra, PhD , Assistant Professor (Research), Using a nonhuman primate model of TB in rhesus macaques via infecting Mycobacterium tuberculosis aerosols to investigate pathogenesis in the lung. (lsu.edu)
  • the International Journal of Tuberculosis and Lung Disease (IJTLD) and Public Health Action (PHA). (wikipedia.org)
  • abnormalities
  • People affected by GLILD may have symptoms such as cough and breathlessness, but may also be asymptomatic, with the condition first detected through abnormalities on lung function tests or a CT scan of the lungs. (wikipedia.org)
  • causes
  • Prolonged exposure to pigeon bloom causes pigeon breeders' disease, reports the British Pigeon Fanciers Medical Research team. (ehow.co.uk)
  • Coal dust alone, even if its silica content is very low, causes a distinctive pattern of change in the lung known as coal workers' pneumoconiosis (also called black lung ). (britannica.com)
  • We also conduct research to understand the causes of deployment-related lung disease, identify new and better diagnostic tools, develop better treatment s and look for ways to prevent these devastating diseases. (nationaljewish.org)
  • In collaboration with the Department of Defense , National Jewish Health is searching for the causes of deployment-related lung diseases that impact our military personnel and veterans. (nationaljewish.org)
  • Centers
  • CDC (Centers for Disease Control and Prevention) [2013a]. (cdc.gov)
  • As one of the largest interstitial lung disease referral centers in the United States, we have access to patients, biological samples and animal models that can help solve the mysteries of these complex diseases and improve care for patients who suffer from them. (nationaljewish.org)
  • The Centers for Disease Control and Prevention estimate that 1 in 11 children and 1 in 12 adults have asthma in the United States of America. (wikipedia.org)
  • types of lung
  • Susceptibility to these types of lung disease has been investigated largely through candidate gene studies, which have been characteristically small, often providing findings that have been difficult to corroborate. (cdc.gov)
  • Exposure
  • Coalworker's pneumoconiosis, also called "black lung disease", is an interstitial lung disease caused by long-term exposure (over 10 years) to coal dust. (wikipedia.org)
  • Indium lung is an interstitial lung disease caused by occupational exposure to indium tin oxide. (wikipedia.org)
  • World Trade Center lung is a cluster of diseases caused by exposure to fallout at Ground Zero of the September 11 attacks in 2001. (wikipedia.org)
  • Although chronic beryllium disease is only caused by exposure to beryllium, inheritance of HLA-DPB1E69 carries an increased risk of between two and 30-fold in beryllium exposed workers. (cdc.gov)
  • In most cases, thickening of the pleura is not associated with disturbance of lung function or with symptoms of exposure to asbestos, although in occasional cases pleuritis is very aggressive and thus may produce symptoms. (britannica.com)
  • It is the oldest known occupational lung disease, and is caused by exposure to inhaled particles of silica, mostlyfrom quartz in rocks, sand, and similar substances. (faqs.org)
  • The 1969 law also set up a black lung disability benefits program tocompensate coal miners who have been disabled by on-the-job dust exposure. (faqs.org)
  • In-theatre exposure to open air burn pits, sandstorms, combat dust, diesel exhaust and other workplace hazards may place deployers at risk for disabling respiratory symptoms and lung diseases. (nationaljewish.org)
  • Indium lung is a rare occupational lung disease caused by exposure to respirable indium in the form of indium tin oxide. (wikipedia.org)
  • Indium lung is caused by exposure to indium tin oxide in a variety of occupational contexts, including reclamation and production. (wikipedia.org)
  • The National Institute of Occupational Safety and Health, Japan (JNIOSH) set limits for acceptable exposure at 0.0003 mg/m3 after the discovery of indium lung. (wikipedia.org)
  • complications
  • As the disease progresses, it can lead to serious, potentially life-threatening complications. (medicalnewstoday.com)
  • These cellular impairments lead to increased susceptibility to the serious complications from lung disease. (wikipedia.org)
  • Although infections and complications of infection such as bronchiectasis are more common complications of CVID in the lung, the presence of immune manifestations including GLILD is important because this has been associated with greater risk of death. (wikipedia.org)
  • Many centres screen for the development of GLILD (and other lung complications) using regular lung function tests and CT scans. (wikipedia.org)