Loading...
  • Head
  • This phase I trial studies how well talactoferrin works in treating patients with relapsed or refractory non-small cell lung cancer (NSCLC) or squamous cell head and neck cancer. (clinicaltrials.gov)
  • This phase I/II trial is studying the side effects of erlotinib and to see how well it works in treating patients with metastatic or unresectable non-small cell lung cancer, ovarian cancer, or squamous cell carcinoma (cancer) of the head and neck. (clinicaltrials.gov)
  • tumor
  • Depending on the type of tumor, paraneoplastic phenomena -symptoms not due to the local presence of cancer-may initially attract attention to the disease. (wikipedia.org)
  • And to increase the throughput of your lung cancer experiments, ATCC has lung cancer cell lines organized into tumor cell panels. (atcc.org)
  • The ATCC Lung Tumor Cell Panel combines authenticated, well-characterized cell lines with mutation data from the Sanger Institute Catalogue of Somatic Mutations in Cancer (COSMIC) to create powerful tools for cancer research and drug discovery. (atcc.org)
  • This type of cancer spreads rapidly and is more likely than other types to have metastasized (cancer cells from the original tumor have spread to another part of the body). (healthcentral.com)
  • The increased differential activity usually results in fewer troubling side effects for cancer patients, particularly less nausea , vomiting , and death of cells in the bone marrow and gastrointestinal tract , and increased effectiveness against tumor cells. (wikipedia.org)
  • In the mediastinum, the lung cancer tends at first to stay on the side where the original tumor started. (wikipedia.org)
  • In most cases, the goal of lung cancer surgery is to remove the entire tumor, including a small amount of normal tissue (about 2 centimetres, 0.8 in) at the margin. (wikipedia.org)
  • EML4-ALK positive lung cancer is a medical term that refers to a primary malignant lung tumor whose cells contain a characteristic abnormal configuration of DNA wherein the echinoderm microtubule-associated protein-like 4 (EML4) gene is fused to the anaplastic lymphoma kinase (ALK) gene. (wikipedia.org)
  • metastasis
  • This growth can spread beyond the lung by the process of metastasis into nearby tissue or other parts of the body. (wikipedia.org)
  • 13. LUNG CANCER GROWTH Very SlowIn Average, it takes 8-15 years to grow 1 centimetre in diameter.But, they have the ability to spread or metastasize to other parts of thebody early in their growth.This process is called early micrometastasis, metastasis that isnot detectable by ordinary means. (slideshare.net)
  • symptom s at the time of diagnosis often reflect invasion of the lymph node s, pleura, the other lung or the metastasis to other organs . (everything2.com)
  • If left untreated, this growth can spread beyond the lungs in a process called metastasis, into nearby tissues or other parts of the body. (wikipedia.org)
  • Deaths
  • Worldwide in 2012, lung cancer occurred in 1.8 million people and resulted in 1.6 million deaths. (wikipedia.org)
  • There will be 158,000 estimated deaths from lung cancer in 1999, which represents 28 percent of all cancer deaths. (healthcentral.com)
  • In 2002, a study in the Journal of the American Medical Association (JAMA) linked for the first time long-term exposure to fine-particle air pollution to lung cancer deaths. (encyclopedia.com)
  • Across the developed world, 90% of lung cancer deaths in men during the year 2000 were attributed to smoking (70% for women). (wikipedia.org)
  • Lung cancer is responsible for 1.3 million deaths worldwide annually, and is the most common cause of cancer-related death in men and the second most common in women. (wikipedia.org)
  • The goals of the campaign are to promote better diagnosis and treatment of the disease, increase research funding, and publicize medical advances and support services that can help reduce the deaths and suffering associated with lung cancer. (dmoztools.net)
  • cigarette
  • Relationship between cigarette consumption per person (blue) and male lung cancer rates (green) in the US over the century. (wikipedia.org)
  • ETS, otherwise known as passive smoking or second-hand smoking, where smoke is inhaled from someone else's cigarette, pipe, or cigar, can increase the risk of developing lung cancer even though you are not smoking yourself. (news-medical.net)
  • diagnosis
  • Overall, 17.4% of people in the United States diagnosed with lung cancer survive five years after the diagnosis, while outcomes on average are worse in the developing world. (wikipedia.org)
  • Because most patients have extensive lung cancer at the time of diagnosis, however, the outlook is generally poor. (everything2.com)
  • Clinical Lung Cancer publishes articles on detection, diagnosis, prevention, and treatment of lung cancer. (wikipedia.org)
  • The diagnosis of lung cancer is based on chest radiograph and computer tomography (CT) scans, and is confirmed by biopsy. (wikipedia.org)
  • Lung cancer biopsies can be taken for two different reasons: Diagnosis: To find out whether an abnormality seen on a chest x-ray or CT scan is indeed lung cancer, and what histological type it is (small cell or non-small cell). (wikipedia.org)
  • Because there is a substantially higher probability of long-term survival following treatment in localized (55%) than in advanced stage (5%), the specific rationale of lung cancer screening is to diagnose the disease in stage I. Research parameters include population cancer-specific mortality, all-cause mortality, long-term survival following diagnosis of cancer, risks of screening and cost-effectiveness. (wikipedia.org)
  • There are typically three objectives applied to the treatment of lung cancer and can vary by patient or individual diagnosis: (1) curing lung cancer, (2) controlling lung cancer, and (3) being comfortable. (wikipedia.org)
  • The Lung Institute at Columbus Regional Hospital is the first Indiana hospital to use the inReach superDimension/Bronchus system along with Cellvizio technology for the diagnosis and treatment of lung disease. (dmoztools.net)
  • Description of a simple technique for computer-aided diagnosis of lung nodules in chest radiographic images. (dmoztools.net)
  • trachea
  • Anatomy of the respiratory system, showing the trachea and both lungs and their lobes and airways. (cancer.gov)
  • prognosis
  • As with most cancers, staging is an important determinant of treatment and prognosis. (wikipedia.org)
  • In general, more advanced stages of cancer are less amenable to treatment and have a worse prognosis. (wikipedia.org)
  • Treatment and prognosis depend upon the histological type of cancer, the stage, and the patient's performance status. (wikipedia.org)
  • The underlying purpose is to describe the extent or severity of an individual's cancer, and to bring together cancers that have similar prognosis and treatment. (wikipedia.org)
  • disease
  • Many people with lung cancer don't experience symptoms until the disease is in an advanced stage. (familydoctor.org)
  • Without smoking, it is believed that lung cancer would be a rare disease. (news-medical.net)
  • The choice of treatment depends on the patient's general health , the stage or extent of the disease, and the type of cancer. (everything2.com)
  • Lung cancer is a disease characterized by uncontrolled cell growth in the lung tissue. (wikipedia.org)
  • The risk of developing lung cancer is higher for those with a family history of the disease. (wikipedia.org)
  • Lung cancer can also spread to distant organs, for example, the liver or adrenal glands, which constitutes the most advanced stage of the disease called stage IV. (wikipedia.org)
  • Staging of lung cancer is of paramount importance as treatment choices are often highly complex, even for physicians with much experience in the field, and the options largely depend on the stage of the disease. (wikipedia.org)
  • The Addario Lung Cancer Medical Institute (ALCMI voiced as Alchemy) is a patient-founded non-profit research consortium established to help make lung cancer a survivable disease. (wikipedia.org)
  • In 2005, the Center for Disease Control and Prevention (CDC) spent $204 million on breast and cervical cancer research. (wikipedia.org)
  • The lack of funding, coupled with the complexity of the disease, has helped prevent lung cancer from making significant advances in its five-year survival rate. (wikipedia.org)
  • Provides information about lung cancer through videos of people sharing their personal stories dealing with the disease. (dmoztools.net)
  • General information on many aspects of the disease from the U.S. National Cancer Institute. (dmoztools.net)
  • 2002
  • These efforts have helped reduce lung cancer death rates in men by 36% over the past two decades and in women by 11% since 2002. (cancer.org)
  • Lung cancer burden between developed and developing countries was nearly equal in 2002, and this concentration of lung cancer burden is thought to increase further in developing countries in the future. (news-medical.net)
  • palliative care
  • Smith is researching the lung cancer care needs and barriers to receiving palliative care specific to minority patients with advanced lung cancer and their caregivers. (cancer.org)
  • Smith notes that minority lung cancer patients often underutilize palliative care. (cancer.org)
  • Smith's goal is for her findings to help inform the development of a culturally-appropriate palliative care intervention to help minority lung cancer patients. (cancer.org)
  • In a 2010 study of patients with metastatic non-small-cell lung cancer, "early palliative care led to significant improvements in both quality of life and mood. (wikipedia.org)
  • chest
  • The lungs are a pair of cone-shaped breathing organs in the chest. (cancer.gov)
  • A thin membrane called the pleura covers the outside of each lung and lines the inside wall of the chest cavity . (cancer.gov)
  • The pleural cavity normally contains a small amount of fluid that helps the lungs move smoothly in the chest when you breathe. (cancer.gov)
  • these cancers are incidentally found on routine chest radiography. (wikipedia.org)
  • Research has not found two other clinically available tests - sputum cytology or chest radiograph (CXR) screening tests - to reduce the overall number of people who die from lung cancer. (wikipedia.org)
  • EML4-ALK
  • EML4-ALK Fusion-A549 Isogenic Cell Line is the first cell line derived from the parental non-small cell lung cancer cell line A549. (atcc.org)
  • Crizotinib shows benefit in a subset of non-small cell lung cancer that is characterized by the EML4-ALK fusion oncogene, and is approved by the FDA. (wikipedia.org)
  • A 2011 consensus recommendation from 37 Canadian lung cancer specialists found that, as of June 2011, there was insufficient evidence to recommend routine screening of lung cancer specimens for EML4-ALK fusions, but that may soon change. (wikipedia.org)
  • survival
  • This bill, which was included in the National Defense Authorization Act of 2013, requires the National Cancer Institute (NCI) to develop scientific frameworks for addressing cancers with survival rates of less than 50 percent. (wikipedia.org)
  • According to the American Cancer Society, the five-year survival rate has remained at approximately 15% since 1971. (wikipedia.org)
  • EGFR
  • Chong is focused on lung cancer patients who have a mutation in a gene called EGFR as this form of lung cancer very often develops resistance to the drug currently used to treat it. (cancer.org)
  • While a very large number of agents targeting various molecular pathways are being developed and tested, the main classes and agents that are now being used in lung cancer treatment include: Inhibitors of Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI's):erlotinib (Tarceva)[unreliable medical source? (wikipedia.org)
  • mediastinum
  • 14. LUNG CANCER SPREADSpread of the tumour can occur by the lymphatic vessels to lymphnodes located within the lung, mediastinum and thorax.Most cancer cells that enter the bloodstream die.If spread by the blood stream, it can lead to deposits of tumour in theliver, opposite lung, bone and brain.The process of determining whether lung cancerhas spread beyond the original tumour is calledstaging. (slideshare.net)
  • Typically, if lung cancer spreads, it first goes to close-by lymph nodes, followed by lymph nodes further away located between the lungs in a space called the mediastinum. (wikipedia.org)
  • prevention
  • One of the main ways we study lung cancer is through long-term cancer prevention studies, which we have been conducting since 1952. (cancer.org)
  • Researchers in the Society's Epidemiology Research Program continue to make new discoveries related to lung cancer by analyzing data on an ongoing basis from Cancer Prevention Study II (CPS-II), which the Society began in 1982. (cancer.org)
  • In 2011, Lung Cancer Alliance supported the Lung Cancer Mortality Reduction Act, which authorized government research agencies with the Department of Health and Human Services, Department of Defense and Department of Veterans Affairs to develop a plan of action to coordinate prevention, early detection and treatment research for lung cancer. (wikipedia.org)
  • It funds lung cancer research, supports the prevention of lung cancer by encouraging and helping people to avoid or quit smoking, and raises general awareness of lung cancer and its symptoms. (wikipedia.org)
  • In 2011 it raised a total of £2.3 million towards lung cancer prevention and care. (wikipedia.org)
  • The Bonnie J. Addario a Breath Away from the Cure Foundation (ABAFTC), now styled Bonnie J. Addario Lung Cancer Foundation (BJALCF) on their website, is a foundation created by Bonnie J. Addario to eradicate lung cancer through research, early detection, education, prevention and treatment. (wikipedia.org)
  • cells
  • The cancer cells of each type grow and spread in different ways. (cancer.gov)
  • Cancer that begins in squamous cells , which are thin, flat cells that look like fish scales. (cancer.gov)
  • Cancer that may begin in several types of large cells. (cancer.gov)
  • Cancer that begins in the cells that line the alveoli and make substances such as mucus . (cancer.gov)
  • Small cell - The cells of this form of cancer are small. (familydoctor.org)
  • They will look at the tissue under a microscope and look for cancer cells. (familydoctor.org)
  • If cancer cells are found in a biopsy, your doctor will do more testing. (familydoctor.org)
  • To breathe new life into your lung cancer research, ATCC provides numerous lung cancer cell lines, human primary cells, and h-TERT-immortalized cell lines. (atcc.org)
  • ATCC retains a vast collection of cell lines derived from the lung or head and neck cells of multiple species. (atcc.org)
  • The function of the cells is to divide, reproduce and repair worn-out or injured lung tissue and to allow for growth. (healthcentral.com)
  • Targeted therapy of lung cancer refers to using agents specifically designed to selectively target molecular pathways responsible for, or that substantially drive, the malignant phenotype of lung cancer cells , and as a consequence of this (relative) selectivity, cause fewer toxic effects on normal cells. (wikipedia.org)
  • The treatment aimed at killing the cancer can also eliminate functioning lung cells (leukocytes). (wikipedia.org)
  • The process of lung cancer development transforms healthy cells into cancer cells, which can then metastasize to different parts of the body. (wikipedia.org)
  • malignant neoplasms
  • Lung cancer is an extremely heterogeneous family of malignant neoplasms , with well over 50 different histological variants recognized under the 4th revision of the World Health Organization (WHO) typing system, currently the most widely used lung cancer classification scheme. (wikipedia.org)
  • Lung cancer is an extremely heterogeneous family of malignant neoplasms, and well over 50 different histopathological variants are currently recognized under the most widely used typing system. (wikipedia.org)