• Clear cell renal cell carcinoma (ccRCC) is the most common type of kidney cancer and accounts for approximately 60% to 70% of all renal tumors [ 1 ]. (hindawi.com)
  • Clear cell renal cell carcinoma (CCRCC) is a common tumor of the urological system for which surgery is the preferred treatment, but there is a lack of therapeutic options after surgery. (biomedcentral.com)
  • Typically, clear cell renal cell carcinoma (CCRCC) is the most important tissue subtype of renal cancer, accounting for 80% of all cases [ 4 ]. (biomedcentral.com)
  • Cabometyx (cabozantinib) developed for the treatment of patients with advanced renal cell carcinoma (RCC) and hepatocellular carcinoma (HCC). (pharmaceutical-technology.com)
  • CheckMate -67T is a Phase 3 randomized, open-label trial evaluating subcutaneous administration of Opdivo co-formulated with Halozyme's proprietary recombinant human hyaluronidase, rHuPH20, or subcutaneous nivolumab (nivolumab and hyaluronidase) compared to intravenous (IV) Opdivo , in patients with advanced or metastatic clear cell renal cell carcinoma (ccRCC) who have received prior systemic therapy. (businesswire.com)
  • Renal cell carcinoma (RCC) is the most common type of kidney cancer in adults, accounting for more than 431,000 new cases and 179,000 deaths worldwide each year. (businesswire.com)
  • Comprehensive Analysis of mC RNA Methylation Regulator Genes in Clear Cell Renal Cell Carcinoma. (cdc.gov)
  • Fig.07 Papillary renal cell carcinoma with intense nuclear and cytoplasmic PAX8 staining. (oncodianova.com)
  • Fig.10 Moderately strong nuclear PAX8 positivity in a chromophobic renal cell carcinoma. (oncodianova.com)
  • Moreover, PAX8 is found in most cases of renal cell carcinoma (all types) and in oncocytoma as well as in thymic tumours. (oncodianova.com)
  • PAX 8 is a useful IHC marker with a wide range of diagnostic applications and appears to be the most specific and sensitive marker for renal cell carcinoma and ovarian non-mucinous carcinoma. (oncodianova.com)
  • The relationship between blood pressure and risk of renal cell carcinoma. (who.int)
  • Epidemiology of Renal Cell Carcinoma: 2022 Update. (who.int)
  • Mycotoxin Exposure and Renal Cell Carcinoma Risk: An Association Study in the EPIC European Cohort. (who.int)
  • Biomarkers of the transsulfuration pathway and risk of renal cell carcinoma in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. (who.int)
  • Adenocarcinomas are most often highly heterogeneous peripheral tumors, and are thought to arise from malignant transformation of primitive cells that can exhibit differentiation characteristics of Club cells, Type II pneumocytes, bronchiolar surface cells, bronchial gland cells, or goblet cells. (wikipedia.org)
  • In such cases, these biphasic tumors are classified as a form of pulmonary blastoma because the presence of the blastomatous cells dramatically worsens the prognosis. (wikipedia.org)
  • Loss of ARID1A expression was not observed in SMBTs, clear cell tumors, or endometriosis. (hindawi.com)
  • A few studies have reported tumors coexisting with SMBTs, such as endometrioid adenocarcinoma [ 4 ] and squamous cell carcinoma [ 5 ]. (hindawi.com)
  • Clear cell tumors were also found in both ovaries. (hindawi.com)
  • CCLC (Clear cell lung carcinoma) was considered by the 2011 WHO classification of lung tumors as a rare cytologic feature of squamous cell or adenocarcinomas. (alliedacademies.org)
  • 17 ] reported the mean and maximum values of pre-SABR standard uptake value to be both significantly correlated with a complete response within 6 months after SABR treatment of lung metastases from various primary tumors. (biomedcentral.com)
  • I've had multiple types of unrelated cancer if you want to count several en situ Squamous cell skin cancer tumors that were surgically removed. (lungevity.org)
  • A family of mesenchymal tumors composed of histologically and immunohistochemically distinctive perivascular epithelioid cells. (curehunter.com)
  • The most common path is the hematogenous spread, which occurs in tumors that have direct venous drainage to the lungs. (medscape.com)
  • Lung tissue that was scarred by a disease or infection, such as scleroderma or tuberculosis , becomes at risk for tumors in that tissue. (webmd.com)
  • Fatty acid synthase expression is related to tumor-infiltrating immune cells in tumors (e.g. (aging-us.com)
  • Data mining for 5′-end CpG island methylation of TUSC3, ATRNL1, POMT1 and SAMD4A in cancer cell lines and primary tumors showed that the epigenetic defect was commonly observed among different tumor types in association with the diminished expression of the corresponding transcript. (oncotarget.com)
  • Non-Small Cell Lung Cancer (NSCLC) was one of the most common malignant tumors in the clinic, with high morbidity and mortality, accounting for about 80 % of the total number of lung cancer in China. (ijpsonline.com)
  • No reactivity has been shown for mucinous ovarian tumors or in germ cell or hematopoietic tumors. (neobiotechnologies.com)
  • This antibody is a useful aid for classification of a variety of tumors, such as some adenocarcinomas of the colon, breast carcinomas, malignant mesothelioma, uterine adenomatoid tumor, lung bronchoalveolar carcinoma, and ovarian endometrioid and serous carcinomas. (neobiotechnologies.com)
  • CMS coverage has been approved under specific clinical scenarios for liquid biopsy for patients with lung cancer , as well NSCLC, colorectal, breast, and other solid tumors . (cdc.gov)
  • The May edition of the Journal of Thoracic Oncology features a study aimed to clarify expression patterns of a novel cancer biomarker, CD24, in non-small cell lung carcinomas (NSCLC) and to correlate the findings to clinicopathologic variables, such as performance status, age, gender and prognostic significance. (scienceblog.com)
  • Stereotactic ablative radiotherapy (SABR) shows a remarkable local control of non-small cell lung cancer (NSCLC) metastases, partially as a result of host immune status. (biomedcentral.com)
  • To that effect, we investigated the ability of pre-SABR immune cells in peripheral blood to predict early tumor response to SABR in patients with lung metastases from NSCLC. (biomedcentral.com)
  • This study included 70 patients with lung metastases from NSCLC who were undergoing SABR. (biomedcentral.com)
  • A pre-SABR CD8+CD28+ T-cell count could predict early tumor response to SABR in patients with lung metastases from NSCLC. (biomedcentral.com)
  • I also had surgery for Stage 1A NSCLC adenocarcinoma. (lungevity.org)
  • I have NSCLC so I can't relate to large cell. (lungevity.org)
  • Adenocarcinoma is the most common kind of NSCLC. (webmd.com)
  • Cigarette smoking is a strong risk factor for developing non-small cell lung cancer (NSCLC). (biomedcentral.com)
  • Current National Comprehensive Cancer Network (NCCN) 2022 guidelines specific to NSCLC (V5.2022) advise plasma cell-free/circulating tumor DNA testing should not be used in lieu of histologic tissue diagnosis, although it can be considered in specific clinical circumstances (i.e., if a patient is not suitable for invasive tissue sampling, if insufficient material following pathologic confirmation or incomplete assessment of all recommended biomarkers in the initial diagnostic setting). (cdc.gov)
  • Between February 2009 and July 2013, 402 patients with clinical stage I non-small cell lung cancer (NSCLC) underwent "non-grasping en bloc MLND" conducted by one surgical team. (medscape.com)
  • By using immunohistochemistry we investigated the expression of EphA2 and EphrinA-1 in 217 early squamous cell cervical carcinomas and examine their prognostic relevance. (medsci.org)
  • The increased levels of EphA2 and EphrinA-1 in a relative high number of early stage squamous cell carcinomas suggested that these two proteins may play an important role in the development of a subset of early cervical cancers. (medsci.org)
  • Squamous cell vaginal cancer spreads slowly and usually stays near the vagina, but may spread to the lungs, liver, or bone. (oncologyforwomen.org)
  • Adenocarcinoma is more likely than squamous cell cancer to spread to the lungs and lymph nodes. (oncologyforwomen.org)
  • FA is a rare tumor, with a relative incidence estimated to be no more than 0.5% of all lung cancers. (wikipedia.org)
  • This type accounts for 30% of lung cancers, and it's more common in men and people who smoke. (webmd.com)
  • Large-cell carcinomas are a group of cancers with large cells that tend to start along the lungs' outer edges. (webmd.com)
  • Small-cell lung cancer makes up 10%-15% of lung cancers. (webmd.com)
  • Additionally, several features (e.g., gene expression, survival prognosis, genetic alteration, DNA methylation, protein phosphorylation, immune cells, or relevant cellular pathways) were gathered to evaluate the regulatory mechanism of FASN in the tumorigenesis of cancers. (aging-us.com)
  • Researchers have designed ever more potent AR-targeting drugs to overcome this hurdle, but some prostate cancers still escape - and it's not been clear why. (mskcc.org)
  • Lung cancer is the most common cancer in the world and, by 2002, there were 1.35 million new cases, representing 12.4% of all new cancers. (touchoncology.com)
  • While stabilisation or even a decrease in the number of lung cancers in males is emerging in most European countries, mortality due to lung cancer in females is increasing. (touchoncology.com)
  • It is the fourth most common cancer, accounting for 7% of female cancers, following breast, lung, and colorectal cancer. (medscape.com)
  • Seromucinous tumor cells were positive for estrogen receptor (ER) and progesterone receptor (PgR) but negative for Napsin A, p504S, and HNF1B. (hindawi.com)
  • These tumor cells had clear cytoplasm and a hobnail-shaped appearance (Figure 2(c) ). (hindawi.com)
  • Many ORs are expressed by tumor cells and tissues, suggesting that they may be associated with cancer progression or may be cancer biomarkers. (bmbreports.org)
  • When the primary tumor invades the venous system, tumor cells embolize to the lungs through the pulmonary or bronchial arteries. (medscape.com)
  • however, some tumor cells pass through the vascular wall and develop parenchymal metastasis in the alveolar space or the interstitium. (medscape.com)
  • In this paper, we consider three such features: tumor mutation burden (TMB, i.e., the total number of SPMs), SCNA burden, and the degree of (genetic) intra-tumor heterogeneity (ITH), which refers to the fact that tumor cells can be grouped in subclones such that the cells within one subclone share similar sets of somatic mutations. (biomedcentral.com)
  • In the past few years, Memorial Sloan Kettering Cancer Center (MSK) researchers found a startling reason: Some prostate tumor cells completely change their identity to survive. (mskcc.org)
  • Circulating tumor DNA (ctDNA) is a specific type of cfDNA that originates from a primary tumor, circulating tumor cells or metastasized cells. (cdc.gov)
  • [ 3 ] Lymphatic spread also occurs to the mediastinal lymph nodes through the thoracic duct, with subsequent retrograde spread to the hilar lymph nodes and then the lungs. (medscape.com)
  • Adenocarcinoma can spread to the lymph nodes, bones, or other organs such as the liver. (webmd.com)
  • FA is an epithelial tumor whose cells and architecture resemble that of fetal lung tissues in the pseudoglandular stage of development (which occurs at about 10-16 weeks gestation in the human), with complex glandular structures and morules with cell nuclei that appear clear due to the accumulation of biotin. (wikipedia.org)
  • We detect mutational signatures in cancer cell line exomes (where matched healthy tissues are not available) by adjusting for the confounding germline mutation spectra across ancestries. (nature.com)
  • In addition, ORs were recently shown to be expressed in many nonolfactory tissues and cells, indicating that these receptors have physiological and pathophysiological roles beyond olfaction. (bmbreports.org)
  • Widely expressed at low levels in adult tissues and fetal brain, lung, liver and kidney. (bioparadigms.org)
  • The term "oncotarget" encompasses all molecules, pathways, cellular functions, cell types, and even tissues that can be viewed as targets relevant to cancer as well as other diseases. (oncotarget.com)
  • Because cigarette smoking and oncogenesis alter lipid metabolism in lung tissue, we hypothesized that the lipid profiles in lung cancer tissues are influenced by cigarette smoking and can reflect the postoperative recurrence risk in smoking lung cancer patients. (biomedcentral.com)
  • Overexpression of Crk was observed at the invasive front of human lung cancer tissues and was significantly associated with poor prognosis. (elsevierpure.com)
  • Since CA125 is highly glycosylated it creates a hydrophilic environment that acts as a lubricating barrier against foreign particles and infectious agents on the apical membrane of epithelial cells.CA125 reacts with both normal tissues and neoplasms of fallopian tube, endometrium, endocervix and mesothelioma. (neobiotechnologies.com)
  • Studies have shown that CA125 reacts with approximately 80% of epithelial ovarian neoplasms of serous, endometrioid, clear cell and undifferentiated types. (neobiotechnologies.com)
  • Approximately eighty percent of endometrial carcinomas are endometrioid adenocarcinomas. (medscape.com)
  • Other histologic subtypes include adenosquamous, clear cell, and papillary serous carcinomas. (medscape.com)
  • Pulmonary carcinoids are well differentiated low to intermediate grade lung neuroendocrine tumours (LNETs), that belong to the group of lung neuroendocrine neoplasms which also include highly aggressive lung neuroendocrine carcinomas (LNECs). (who.int)
  • SFTs of the pleura are localized mesenchymal neoplasms composed of fibroblastlike cells believed to arise from the subpleural connective tissue. (medscape.com)
  • Meningiomas , as defined by the 2016 World Health Organization (WHO), are "a group of mostly benign, slow-growing neoplasms that most likely derive from the meningothelial cells of the arachnoid layer. (medscape.com)
  • These data have been combined with previously published LNET data to perform integrative analysis using multi-omics factor analysis (MOFA), resulting in a molecular map of lung neuroendocrine neoplasms for exploration. (who.int)
  • 2004). Pathology and Genetics of Tumours of the Lung, Pleura, Thymus and Heart (PDF). (wikipedia.org)
  • Immunohistochemistry and electron microscopy are invaluable techniques for diagnosis and subclassification, but our intention was to render the classification simple and practical to every surgical laboratory, so that most lung tumours could be classified by light microscopic criteria. (ersjournals.com)
  • In 1994, the WHO adopted the International Association for the Study of Lung Cancer (IASLC) pathology panel to comprise the core membership of the WHO committee, to develop a new revised classification of lung and pleural tumours. (ersjournals.com)
  • We report a sporadic case of an 84-year-old man with a pacemaker diagnosed with heart osteosarcoma, hepatocellular and prostatic adenocarcinoma and presenting with symptoms mimicking infective endocarditis. (journalmc.org)
  • Aruj Chawla, DO discusses a study that brings about a novel method to analyze vascular involvement in pancreatic ductal adenocarcinomas. (arrs.org)
  • Soft-tissue metastases from a pancreatic adenocarcinoma are extremely rare. (amjcaserep.com)
  • We report the case of a 74-year-old woman who presented with late-onset (recurrent disease), solitary, subcutaneous metastasis in the posterior aspect of the left thigh, deriving from a pancreatic head adenocarcinoma, 2 years after initial treatment with R0 resection (pancreaticoduodenectomy) and adjuvant chemotherapy. (amjcaserep.com)
  • Solitary soft-tissue metastasis from a pancreatic adenocarcinoma after initial curative treatment is very rare. (amjcaserep.com)
  • The JTO is a prized resource for medical specialists and scientists who focus on the detection, prevention, diagnosis and treatment of lung cancer. (scienceblog.com)
  • The main of this presentation is to emphasize the importance of a multidisciplinary approach including pathologists, oncologists and radiologists to confirm the diagnosis as well for an adequate therapeutic management of this unusual entity of lung cancer. (alliedacademies.org)
  • sometimes the diagnosis is changed from Large cell to adeno or squamous. (lungevity.org)
  • There were 52 patients diagnosed with stage I or II lung cancer by computed tomography and clinical diagnosis in the lung cancer group and 45 patients with benign lesions in the benign lesion group. (ijpsonline.com)
  • The recommendations based on a systematic review determined that there was insufficient evidence to inform the use of cfDNA or ctDNA for diagnosis of primary lung adenocarcinoma or identification of mutations at the time of EGFR TKI resistance. (cdc.gov)
  • Only adenocarcinoma in situ is identified in the histologic sections examined. (cancer.org)
  • Although some of the observed variants, such as chondroid meningiomas, clear-cell meningiomas, papillary meningiomas, and rhabdoid meningiomas, are associated with unfavorable prognoses, the other histologic patterns are not indicators of unfavorable biologic behavior. (medscape.com)
  • Lymphatic spread occurs to the lungs, pleura, or mediastinum. (medscape.com)
  • In this report, we highlight an unusual site of metastasis of an endometrial adenocarcinoma to the small intestine. (karger.com)
  • Our scientists pursue every aspect of cancer research-from exploring the biology of genes and cells, to developing immune-based treatments, uncovering the causes of metastasis, and more. (mskcc.org)
  • Axial CT scan in a 58-year-old man with malignant melanoma shows multiple round nodules and masses of varying sizes in both lungs, consistent with metastases. (medscape.com)
  • [ 1 ] Lungs are the second most frequent site of metastases from extrathoracic malignancies. (medscape.com)
  • [ 3 ] Malignancies can reach the lung through 5 different pathways-hematogenously through the pulmonary or bronchial artery, lymphatics, pleural space, airway, or direct invasion. (medscape.com)
  • Twenty percent of metastatic disease is isolated to the lungs. (medscape.com)
  • To identify operable lung cancer patients with risk for metastatic relapse we search for new prognostic biomarkers based on analysis of genome-wide gene expression data and conventional protein marker validation based on analysis of primary tumor tissue. (lu.se)
  • Here, we demonstrated that Crk induced EMT in A549 human lung adenocarcinoma cells through differential regulation of Rac1/Snail and RhoA/Slug, leading to decreased expression of E-cadherin and increased N-cadherin, fibronectin, and MMP2 expression. (elsevierpure.com)
  • 18 P53 transversion mutation (G:C T:A) is of high frequency in human lung cancer and probably the result of DNA damage induced by carcinogens of tobacco smoke. (touchoncology.com)
  • Proteomic grade correlations identified protein kinases having functional impact in vitro in uterine endometrial cancer cells, including MAP3K2, MASTL, and TTK. (nih.gov)
  • Fig.18 Epithelium of the uterine tuba with clear nuclear PAX8 staining. (oncodianova.com)
  • According to this hypothesis, cells exposed to GNG7 will stop further proliferation and start the differentiation process mediated by G protein signals. (biomedcentral.com)
  • Despite significant advances in understanding nephron segment patterning, many questions remain about the underlying genes and signaling pathways that orchestrate renal progenitor cell fate choices and regulate differentiation. (mdpi.com)
  • FA can occur in combination with other forms of lung cancer, particularly other variants of adenocarcinoma. (wikipedia.org)
  • There also seems to be an association with clear cell lung cancer variants. (wikipedia.org)
  • Synovial sarcomas encompass both biphasic (epithelial and spindle cell components) and monophasic (purely spindle cell) variants. (medscape.com)
  • PAX8 plays a central role for the expression of thyroid-specific genes and thus, in development of thyroid follicular cells. (oncodianova.com)
  • However, the predictors of immune cells for tumor response after SABR are unknown. (biomedcentral.com)
  • Lung-specific intercurrent clinically significant illnesses including, but not limited to, any underlying pulmonary disorder (eg, clinically significant pulmonary emboli within 3 months of treatment, severe asthma, severe chronic obstructive pulmonary disease, restrictive lung disease, clinically significant pleural effusion etc. (who.int)
  • Tissue resembling FA can also be found admixed with a component made up of primitive blastoma-like cells. (wikipedia.org)
  • In non-tumoral lung tissue, transversion and DNA adducts were more frequent in females even though tobacco exposure was less than in males. (touchoncology.com)
  • While FA can be diagnosed via biopsy, bronchial brushings, and immunocytochemistry, examination of the whole tumor is required to rule out biphasic pulmonary blastoma, a mixed tumor of higher aggressiveness, wherein FA occurs admixed with primitive blastoma cells. (wikipedia.org)
  • Many of the cysts and the low papillary growth lesions were lined by tall columnar mucinous or cuboidal ciliated serous cells (Figure 2(b) ). (hindawi.com)
  • Clinical data of 97 patients initially diagnosed with lung lesions in our hospital from January 2018 to December 2019 were collected and divided into the lung cancer group and benign lesion group. (ijpsonline.com)
  • Developmental lesions such as heterotopia of meningothelial cells in the scalp are believed to be the origin of meningiomas under the scalp and skin of the head. (medscape.com)
  • Hello everyone, I am 56-year old former smoker (quit 7 years ago) and was just diagnosed with Adenocarcinoma In Situ based on needle biopsy done on a 1.3cm nodule in my right middle robe. (cancer.org)
  • Stage 1A and resection of an en situ tumor is the best recipe for no evidence of disease (NED). (lungevity.org)
  • Pre-SABR peripheral CD8+ T cell count, CD8+CD28+ T-cell count, CD8+CD28− T-cell count, CD4+ T-cell count, and Treg-cell count were measured using flow cytometry. (biomedcentral.com)
  • Moreover, there is now a convergence between lung cancer incidence in the youngest birth cohorts, reflecting the convergence in cigarette use in males and females.6 In Europe, about 70% of lung cancer cases in females are attributed to an active smoking habit versus 85% in males, 7 whereas in Asia very few lung cancer cases in females are attributable to tobacco smoking. (touchoncology.com)
  • Background: In some settings, lung cancer incidence appears higher among disadvantaged groups. (who.int)
  • We analyzed the harmonized database of the Lung Cancer Cohort Consortium (LC3) to assess the relationship between socioeconomic status and lung cancer incidence across different world regions. (who.int)
  • Among current/former smoking participants, higher educational level was associated with decreased lung cancer incidence in nearly all cohorts. (who.int)
  • I had a grade 1, stage 1 breast cancer, and also a grade 3 stage 3 clear cell cervical. (lungevity.org)
  • The lung cancer was discovered in a routine CT scan for keeping watch for metasteses from the cervical. (lungevity.org)
  • I carry the brac2 gene but there does not seem to be any correlation with breast and primary lung cancer. (lungevity.org)
  • Different reports have shown that adenocarcinomas of lung and breast are negative for PAX8-expression. (oncodianova.com)
  • 2 In females, mortality due to lung cancer has been greater than mortality due to breast cancer since 1987. (touchoncology.com)
  • Chest tomosynthesis is another low-dose technique with higher sensitivity that is used in the detection of lung nodules. (medscape.com)
  • Multiple pulmonary nodules in my lung were first discovered by CT (taken because I was feeling shortness of breath) in 2005 and they were monitored every 6 months for three years and every year after that and no change in size was observed in any of the nodules until the last CT taken two weeks ago. (cancer.org)
  • [ 4 , 5 ] are small perivascular nodules that are histologically and ultrastructurally identical to meningothelial cells of the CNS. (medscape.com)
  • These nodules probably represent the origin of primary meningiomas in the lung. (medscape.com)
  • Ferroptosis-inducing factors can directly or indirectly affect glutathione peroxidase through different pathways, resulting in a decrease in antioxidant capacity and accumulation of lipid reactive oxygen species (ROS) in cells, ultimately leading to oxidative cell death. (nature.com)
  • The innovative project contains three topics including cell of origin, oncogenic processes, and oncogenic pathways. (boldbusiness.com)
  • The third summary paper highlights the genomic changes in 10 key signaling pathways that have the capacity to control the levels of the life cycle, growth, and death of each cell. (boldbusiness.com)
  • MSK researchers Charles Sawyers and Dana Pe'er discovered that inflammatory signaling pathways play a key role when prostate cancer cells convert to a different cell type - a transformation known as lineage plasticity. (mskcc.org)
  • It has been 17 years since the World Health Organization (WHO) classification was updated in 1981 1 , and since this time considerable progress has been made in understanding the epidemiological histogenetic and molecular biology of lung cancer. (ersjournals.com)
  • Consequently, novel objective biomarkers that reflect postoperative risk in lung cancer patients who smoke must be identified. (biomedcentral.com)
  • From our data, we propose three PC isomers, PC (14:0_18:2), PC (16:1_16:1), and PC (16:0_16:2), and a lipid peak of m/z 736.5276 as novel candidate biomarkers for postoperative recurrence risk in lung ADC and SQCC patients who are smokers. (biomedcentral.com)
  • By characterization of the genomic, transcriptional, and DNA methylation landscape in lung cancer subgroups defined by histology and other clinicopathological factors in both own and public cohorts we search for new molecular subgroups of potential clinical relevance, additional targets for synergistic treatment, and a deepened understanding of the molecular pathogenesis. (lu.se)
  • ctDNA is currently the most common form of liquid biopsy, a term used to refer to utilizing circulating cancer cells, DNA and other omic markers from blood or fluid sample. (cdc.gov)
  • Likewise, ZSCAN18 expression was significantly reduced in a panel of GC cell lines as a result of the densely methylated ZSCAN18 promoter. (biomedcentral.com)
  • We also confirmed that ZSCAN18 high expression inhibited the proliferation of GC cells, both in vitro and in vivo. (biomedcentral.com)
  • Suitability of an antigen for therapy is dependent on various factors including but not limited to the nature of the antigen (e.g. accessibility, abundance, location of expression on cancerous cells etc.), therapeutic approach, antibody affinity and other pharmacokinetic properties. (justia.com)
  • To tackle this issue, we have used cancer cells genetically deficient for the DNA methyltransferase enzymes in conjuction with circRNA expression microarrays. (oncotarget.com)
  • On physical examination, she had a temperature of 38.5°C, with bilateral wheezing at lung auscultation. (cdc.gov)