• Power lifting can improve total body bone mineral density (BMD), but improvements in the regions most susceptible to injury (femoral neck and lumbar vertebrae) have not been demonstrated. (wku.edu)
  • To examine differences in total BMD and BMD at the femoral neck and lumbar vertebrae between female power lifters (PL), Olympic lifters (OL), soccer players (SP) and recreationally active individuals (RA). (wku.edu)
  • Total BMD, BMD at lumbar vertebrae L1-L4, and BMD at the femoral neck of the dominant leg were measured along with body composition (total fat mass, lean mass, and percent body fat) with dual-energy x-ray absorptiometry. (wku.edu)
  • The lumbar vertebrae are the 5 largest and strongest of all vertebrae in the spine. (medscape.com)
  • The strongest stabilizing muscles of the spine attach to the lumbar vertebrae. (medscape.com)
  • Fractures of lumbar vertebrae, therefore, occur in the setting of either severe trauma or pathologic weakening of the bone. (medscape.com)
  • DEXA-validated lumbar VBQ was calculated using median signal intensity (MSI) of the L1-L4 vertebrae and L3 CSF. (europeanspinejournal.org)
  • Bone mineral density (BMD) of the whole-body, proximal femur and lumbar vertebrae was measured by dual-energy X-ray absorptiometry (DXA). (frontiersin.org)
  • Whole-body (WB) and lumbar spine (LS) vertebrae L1 to L4 BMC and bone mineral density (BMD) were measured. (contemporarypediatrics.com)
  • To estimate how axial rotation of lumbar vertebrae quantitatively affects bone mineral density, as measured by dual energy X-ray absorptiometry in the anteroposterior plane. (hkmj.org)
  • Cadaver lumbar vertebrae (L2 to L4) were removed from four adults. (hkmj.org)
  • The measured bone area increased approximately 24% and the bone mineral density decreased approximately 19% when the vertebrae were rotated by 45 degrees. (hkmj.org)
  • The spine scans provide bone measurements for the total spine and vertebrae L1 - L4. (cdc.gov)
  • Osteoporosis is the underlying cause of many lumbar fractures, especially in postmenopausal women. (medscape.com)
  • Midline back pain is the hallmark symptom of lumbar compression fractures. (medscape.com)
  • In the past, treatment options for lumbar fractures were quite limited, with bracing and rest prescribed most often. (medscape.com)
  • Bone loss (osteoporosis) and spinal fractures are serious side effects of this therapy. (cochrane.org)
  • Based on moderate- to high-certainty evidence, we found that bisphosphonates are beneficial in preventing new spinal fractures and preventing and treating steroid-induced bone loss at the lumbar spine and femoral neck. (cochrane.org)
  • Overall, our review supports the use of bisphosphonates to reduce the risk of spinal fractures and in the prevention and treatment of steroid-induced bone loss. (cochrane.org)
  • The corresponding increased risk of pathologic bone fractures constitutes a reduction in future quality of life. (cun.es)
  • However, this FDA-approved therapy has become even more controversial now that it has been linked to atypical bone fractures after long-term use. (anh-usa.org)
  • As osteoporosis expert Lara Pizzorno explains, bisphosphonate drugs help prevent fractures in the short-term by suppressing osteoclasts, the cells that remove injured and damaged bone. (anh-usa.org)
  • The USPSTF found convincing evidence that bone measurement tests are accurate for predicting osteoporotic fractures in women and men. (uspreventiveservicestaskforce.org)
  • While several bone measurement tests similarly predict risk of fracture, DXA directly measures bone mineral density (BMD), and most treatment guidelines use central DXA to define osteoporosis and the treatment threshold to prevent osteoporotic fractures. (uspreventiveservicestaskforce.org)
  • This study examined the impact of physical activity on bone mineral density, so those increases in BMD were natural and likely to help those participants maintain active lives while avoiding fractures. (saveourbones.com)
  • A clinical practice guideline from the American College of Physicians on treatment to prevent fractures in men and women with low bone density or osteoporosis includes six recommendations: two strong recommendations, based on high- or moderate-quality evidence, and four weak ones, based on low-quality evidence. (medscape.com)
  • Injuries to the thoracolumbar and lumbar spine constitute most of these fractures. (medscape.com)
  • This article reviews the diagnosis and management of acute lumbar vertebral fractures. (medscape.com)
  • Accordingly, cases with osteopenia also present high rates of bone fractures 5 . (bvsalud.org)
  • Such parameters may also provide useful information for the diagnosis of osteoporotic alterations and prediction of bone fractures 6,7 . (bvsalud.org)
  • Skeletal weakness leads to fractures with minor or inapparent trauma, particularly in the thoracic and lumbar spine, wrist, and hip (called fragility fractures). (msdmanuals.com)
  • Pelvic Fractures Pelvic fractures can involve the pubic symphysis, innominate bones, acetabulum, sacroiliac joint or sacrum. (msdmanuals.com)
  • The practice of multicomponent exercise has been proposed to Ejercicio improve the physical and cognitive functionality of the older adult, reduce the frequency of falls and fractures, and prevent multicomponente en sarcopenia. (bvsalud.org)
  • A literature search was performed in the Hinari, PubMed, Scopus and Embase efecto en el síndrome de databases, using the Boolean operators "AND" and "OR" and as keywords "frailty", "older adult", "falls", "fractures", "sarcopenia" to fragilidad delimit useful literature for this research. (bvsalud.org)
  • Differences in Bone Mineral Density at the Femoral Neck and Lumbar Regions across Female Soccer Players, Olympic Lifters and Power Lifters" by Woohyoung Jeon, John Michael Harrison et al. (wku.edu)
  • Olympic lifting involves both high- and odd-impact loading at the femoral neck and lumbar regions, but comparisons in BMD across sport-specific athletes have not yet been made. (wku.edu)
  • BMD at the femoral neck was greater in SP than in PL, with no difference between OL and PL. At lumbar spine sites L2 - L4, there was no difference across the three athletic groups. (wku.edu)
  • Olympic lifters showed similar BMD at the femoral neck as soccer players and similar BMD in the lumbar spine as power lifters. (wku.edu)
  • Calcium intake correlated positively with femoral (r = 0.19-0.28, p = 0.03-0.003), but not with lumbar BMD. (nih.gov)
  • Body height was the best predictor of lumbar and femoral neck area. (nih.gov)
  • Patients had decreased lumbar and femoral BMD. (cun.es)
  • Bone mineral density was above the expected range for his age on the lumbar spine and femoral neck. (fluoridealert.org)
  • Three co-primary outcomes (all reported as T-scores) were defined: BMD of the left femoral neck and the lumbar spine, and the trabecular bone score (TBS). (bmj.com)
  • In both adjusted and unadjusted analyses, PPI users had lower BMD at both the left femoral neck and the lumbar spine ( Table 1 ). (bmj.com)
  • After two years of treatment, differences in BMD were 7.6% at the lumbar spine, 4.7% at the total hip and 3.6% at the femoral neck. (pharmatimes.com)
  • After three years of treatment with Prolia, differences in bone mineral density were 7.9% at the lumbar spine, 5.7% at the total hip and 4.9% at the femoral neck. (pharmatimes.com)
  • The participants' bone mineral density was measured in the L1-L4 lumbar spine, the wrist, and the femoral neck. (b-s-h.org.uk)
  • Bone mineral density measurements were carried out using dual energy X-ray absorptiometry at both the lumbar spine [AP: L1-L4] and femoral hip (neck, trochanter). (who.int)
  • The BMD of the mandible was correlated with the BMD of the lumbar spine and femoral neck, in osteopenia and osteoporosis cases 8 . (bvsalud.org)
  • To assess determinants of bone mineral density (BMD) at the spine and proximal femur, a randomly selected sample of 140 Finnish men aged 54-63 years was measured using fan beam dual-energy X-ray absorptiometry. (nih.gov)
  • One hundred and seven patients (58 men) aged 18-60 years underwent dual-energy X-ray absorptiometry scanning of the lumbar spine and hip, radiology of the spine and biochemical studies. (nih.gov)
  • BMD was measured by dual-energy x-ray absorptiometry, at clinical remission, for lumbar spine and the neck of the femur in 38 osteosarcoma and 25 Ewing's sarcoma patients. (cun.es)
  • The most commonly used test is central dual-energy x-ray absorptiometry (DXA) of the hip and lumbar spine. (uspreventiveservicestaskforce.org)
  • Dual-energy X-ray Absorptiometry (DXA) scans were used to measure bone mineral density and total body fat percentage. (saveourbones.com)
  • Using dual energy X-ray absorptiometry, the bone mineral content, bone area, and bone mineral density were measured in the neutral position and with vertebral axial rotation in increments of 7.5 degrees, up to a maximum of 45 degrees. (hkmj.org)
  • These results suggest that for patients with rotational deformity of the spine, such as scoliosis, measurements of lumbar spine bone mineral content by dual energy X-ray absorptiometry is not affected, while bone mineral density measurements are not reliable. (hkmj.org)
  • BMD of the lumbar spine, L2-L4, and the neck of the left femur were measured by dual energy X-ray absorptiometry. (who.int)
  • Users of the 2005-2006 dual-energy X-ray absorptiometry spine bone data (DXXSPN_D) are encouraged to read the documentation before accessing the data file. (cdc.gov)
  • Diagnosis is currently based mainly on bone mineral density (BMD) measurements using dual-energy X-ray absorptiometry (DXA), considered the "gold standard" method. (bvsalud.org)
  • Osteoporosis is defined as a bone mineral density of 2.5 standard deviations or more below the mean value for a young woman at either the femur neck or the lumbar spine, or both locations, as measured by dual energy x-ray absorptiometry. (cdc.gov)
  • Combined amplitude and high-frequency training for one year had no ameliorating effect on DXA and HR-pQCT bone parameters in physically inactive postmenopausal women. (frontiersin.org)
  • This longitudinal preliminary study is the first to demonstrate that smoking and depressive symptoms in adolescent girls have a negative impact on adolescent bone accrual and may become a red flag for a future constrained by low bone mass or osteoporosis and higher fracture rates in postmenopausal years. (scienceblog.com)
  • Romosozumab was found to significantly increase bone mineral density and bone content in the spine and hip in postmenopausal women compared to baseline and also compared to teriparatide and placebo, as presented at the European League Against Rheumatism Annual Congress (EULAR 2014). (empr.com)
  • Lead investigator Professor Harry K. Genant of the University of California an Francisco reported that these results "support the continued clinical investigation of romosozumab as a potential treatment for postmenopausal women with osteoporosis with established bone mineral density deficit who are at increased risk of fracture. (empr.com)
  • ABSTRACT To test the hypothesis that regional fat and not total body weight has a protective effect on bone mineral density (BMD) in postmenopausal women, a cross-sectional study was conducted during the period from March 2008 to June 2009 on 303 healthy postmenopausal women presenting to the osteoporosis unit for screening purposes. (who.int)
  • BACKGROUND: Osteoporosis (OP) is a pathology characterized by bone fragility affecting 30% of postmenopausal women, mainly due to estrogen deprivation and increased oxidative stress. (bvsalud.org)
  • CONCLUSIONS: These results demonstrate for the first time that postmenopausal OP patients have a deficit in bone autophagy level and suggest that HUNK could be the factor linking estrogen loss and autophagy decline. (bvsalud.org)
  • Prevalence of vitamin d deficiency in patients with lumbar spinal stenosis and its relationship with pain. (vitamindwiki.com)
  • BACKGROUND: Patients with lumbar spinal stenosis (LSS) are at a great risk of a fall and fracture, which vitamin D protects against. (vitamindwiki.com)
  • A twice-yearly injection of denosumab could improve spinal bone mineral density of patients with osteoporosis caused by transfusion-dependent thalassaemia (TDT), according to a new study. (b-s-h.org.uk)
  • Quality control procedures for osteoporosis of the lumbar spinal of fracture) during menopause than were followed in accordance with the and the neck of the left femur. (who.int)
  • In the early years of the 20th century, Albee popularized bone grafting in spinal surgery. (medscape.com)
  • Since Mixter and Barr first described an operative procedure for the management of lumbar disk disease, the goals of spinal surgery have been decompression of the neural elements and preservation of normal anatomy and biomechanics. (medscape.com)
  • Quantitative CT scans are primarily used to evaluate bone mineral density at the lumbar spine and hip. (lilesnet.com)
  • Anteroposterior and lateral views of the lumbar and thoracic spines are usually the minimum studies needed. (medscape.com)
  • In most cases, rehabilitation begins with the patient in a thoracic-lumbar-sacral orthosis (TLSO). (medscape.com)
  • To evaluate the associations among the validated lumbar vertebral bone quality (VBQ) score, and cervical and thoracic VBQ scores. (europeanspinejournal.org)
  • Radiographic records of 100 patients who underwent synchronous MRI of the cervical, thoracic, and lumbar spine were retrieved. (europeanspinejournal.org)
  • Thoracic VBQ provides values representative of the validated lumbar VBQ score. (europeanspinejournal.org)
  • Three finite element (FE) models of the L1-S1 lumbar spine were established according to the three human cadaveric lumbar specimens. (biomedcentral.com)
  • Eighteen working age cadaveric lumbar motion segments (average age 49 years +/- 17 SD) were subjected to a fatigue loading regimen simulating lumbar loads when lifting a 9-kg box in three angles of torso flexion (0, 22.5, and 45 deg). (cdc.gov)
  • After World War II, scientists at the Navy Tissue Bank in Bethesda, Maryland, investigated the preservation, sterilization, and distribution of cadaveric allografts and revealed that the freezing of bone reduces its immunogenicity. (medscape.com)
  • Dual-energy radiographic absorptiometry (DRA) scanning is currently the most widely used method to measure bone mineral density. (medscape.com)
  • Bone mineral density (BMD) of the lumbar spine and the radial diaphysis were measured by dual X-ray absorptiometry (DXA), second metacarpal cortical thickness was measured on hand radiographs, and these results were expressed as Z-scores (standard deviations from the mean). (northwestern.edu)
  • 27.3 kg/m2 and obese prevalence of low bone mass is higher ergy X-ray absorptiometry (DEXA). (who.int)
  • Clinical Cases in Mineral and Bone Metabolism. (wikipedia.org)
  • Serum markers of bone metabolism were: OC, PICP, ICTP, 25-OH vit D and 1,25-(OH)(2) vit D, IGF-I, IGFBP-3 and intact PTH. (cun.es)
  • As evidenced by the present study, assessment of serum 25-OHD and bone mineral density are recommended in LSS patients with severe pain, and active treatment combining vitamin D, calcium, or bisphosphonate should be considered according to the status of the bone metabolism. (vitamindwiki.com)
  • Vitamin K functions as a coenzyme for vitamin K-dependent carboxylase, an enzyme required for the synthesis of proteins involved in hemostasis (blood clotting) and bone metabolism and other diverse physiological functions [ 3 , 5 ]. (nih.gov)
  • Skeletal manifestations include a selective cortical bone loss. (medscape.com)
  • A number of recent studies, for example, have found that heavy tea drinkers can develop skeletal fluorosis - a bone disease caused by excessive intake of fluoride. (fluoridealert.org)
  • Appreciation of the significant amounts of F in some modern preparations of tea suggested to us that [skeletal fluorosis] caused our patient's high bone mass when she recounted her remarkable volume of instant tea consumed over three decades. (fluoridealert.org)
  • Denosumab is also approved (and marketed as Xgeva) for the prevention of skeletal-related events in adults with bone metastases from solid tumours. (pharmatimes.com)
  • This skeletal disorder is characterized by bone fragility due to deterioration of the bone micro-architecture, which is related to bone strength and quality 1,2 . (bvsalud.org)
  • 15 micromol/L). Although the clinical presentation of the patients varied, all 4 had an unexpectedly elevated spine bone mineral density that was proportionately higher than the bone mineral density at the hip. (fluoridealert.org)
  • Subsequent dosage adjustment may be made based upon the individual clinical and bone mineral density responses. (centerwatch.com)
  • Effect of vitamin D supplementation on bone mass in infants with 25-hydroxyvitamin D concentrations less than 50 nmol/L: aprespecified secondary analysis of a randomized clinical trial. (contemporarypediatrics.com)
  • Clinical bone transplantation began with the transfer of a free autograft by Walther in 1820 and a free allograft by Macewen in 1878. (medscape.com)
  • However, futures studies should aim at investigating how BMD of the total body and BMAD of the lumbar spine progress when they progress further into adulthood, and what the long-term clinical implications will be. (medscape.com)
  • Lumbar BMD Z-scores were significantly greater than those for radial BMD and cortical thickness. (northwestern.edu)
  • That was based on a study of 1,468 men which showed that BMD was significantly higher at the lumbar spine after two years versus placebo. (pharmatimes.com)
  • Children with cow's milk allergy have significantly lower calcium intake and bone mineral density (BMD) scores compared with children without this allergy, according to a study published in Pediatrics . (clinicaladvisor.com)
  • Children with cow's milk allergy had significantly lower lumbar spine BMD z scores compared with controls. (clinicaladvisor.com)
  • Investigators found that while smokers entered adolescence with equivalent levels of lumbar spine and total hip BMD, overall BMD accrual across adolescence was significantly lower as smoking frequency increased. (scienceblog.com)
  • Girls with higher levels of symptoms had significantly lower lumbar spine BMD consistently across adolescence. (scienceblog.com)
  • At the hip, trabecular bone mineral density gains were significantly larger with romosozumab than teriparatide (10.8% vs. 4.2%, P =0.01). (empr.com)
  • ß-CTX levels in osteoporotic bone marrow were significantly higher. (bvsalud.org)
  • RESULTS: The protein expression level of the autophagosome marker LC3-II was significantly decreased in bone of OP patients relative to the control group. (bvsalud.org)
  • In addition, the protein expression of the hormonally upregulated neu-associated kinase (HUNK), which is upregulated by female hormones and promotes autophagy, was also significantly reduced in bone of the OP group. (bvsalud.org)
  • Similarly, the proportion of patients with a BMAD of the lumbar spine SDS of -2 or lower did not differ significantly from the expected. (medscape.com)
  • The main effects of parathyroid hormone are to increase the concentration of plasma calcium by increasing the release of calcium and phosphate from bone matrix, increasing calcium reabsorption by the kidney, and increasing renal production of 1,25-dihydroxyvitamin D-3 (calcitriol), which increases intestinal absorption of calcium. (medscape.com)
  • These prepubertal children with persistent [cow's milk allergy] had lower lumbar spine BMD z scores than children with [non-cow's milk allergies], which likely resulted from lower calcium intake," wrote the researchers. (clinicaladvisor.com)
  • et la consommation d'aliments riches en calcium. (who.int)
  • Le niveau d'activité physique était supérieur après l'intervention, mais l'apport en calcium n'avait pas augmenté ( p = 0,041). (who.int)
  • Lumbar Spine and Proximal Femur Bone Mineral Density, Bone Mineral Content, and Bone Area: United States, 2005-2008. (cdc.gov)
  • BMD and BMAD peak between ages 18-20 in girls and 18-23 in boys and are the main determinants of bone strength in later life. (medscape.com)
  • The trabecular bone score (TBS) is an indirect measure of the microarchitecture of the trabeculae, or lattice structures, that compose the trabecular (spongy) bone in the lumbar spine. (cdc.gov)
  • To evaluate the problem we measured bone mineral density (BMD) and serum markers of bone formation and resorption in a series of pediatric patients with bone tumors. (cun.es)
  • Normally, bone formation and resorption are closely balanced. (msdmanuals.com)
  • Correlation analysis showed a significant positive correlation between the degree of rotation and measured bone area, a significant negative correlation between degree of rotation and bone mineral density measurements, but no significant correlation between degree of rotation and measured bone mineral content. (hkmj.org)
  • However, little is known about the differences in sensitivity and specificity among these measurements for screening low bone mineral density (BMD). (bvsalud.org)
  • These measurements have been used as indices to predict osteopenia and osteoporosis since they are correlated with systemic bone mineral density (BMD) values measured with DXA 15 . (bvsalud.org)
  • INTRODUCTION: This study examines bone turnover marker (BTM) variations between bone marrow and peripheral blood in osteoporotic and non-osteoporotic patients. (bvsalud.org)
  • RESULTS: Osteoporotic patients exhibited elevated ß-CTX and OC levels in peripheral blood, indicating heightened bone resorption and turnover. (bvsalud.org)
  • Osteoporotic bone loss affects cortical and trabecular (cancellous) bone. (msdmanuals.com)
  • Bone microarchitecture of the distal non-dominant radius and tibia was measured by high-resolution peripheral quantitative computed tomography (HR-pQCT). (frontiersin.org)
  • Quantitative computed tomography (QCT) is a medical technique that measures bone mineral density (BMD) using a standard X-ray Computed Tomography (CT) scanner with a calibration standard to convert Hounsfield Units (HU) of the CT image to bone mineral density values. (lilesnet.com)
  • Osteoporosis is a progressive metabolic bone disease that decreases bone mineral density (bone mass per unit volume), with deterioration of bone structure. (msdmanuals.com)
  • NEW YORK (Reuters Health) - Bone mineral density increases during long-term growth hormone treatment but decreases after cessation of treatment in young adults born small for gestational age, researchers from The Netherlands report. (medscape.com)
  • Serum markers of bone formation (PICP and OC) and resorption (ICTP) were, throughout, lower than reference values. (cun.es)
  • Furthermore, severe back pain, and severe back and leg pain were also associated with higher incidence of osteoporosis and higher level of bone resorption marker (serum CTx). (vitamindwiki.com)
  • All scans were performed by regression model was done for detec- more body fat have lower rates of bone trained physicians and analysed by the tion of the independent risk factors resorption (an independent predictor researcher. (who.int)
  • After achieving its peak, bone mass plateaus for about 10 years, during which time bone formation approximately equals bone resorption. (msdmanuals.com)
  • Trabecular bone loss occurs more rapidly than cortical bone loss because trabecular bone is more porous and bone turnover is higher. (msdmanuals.com)
  • In addition, bone microarchitecture as a potential mediator of fracture risk has not been studied. (bmj.com)
  • Objectives To assess the effect of regular PPI intake on bone mineral density (BMD) and microarchitecture in patients with iRMDs. (bmj.com)
  • The latter is a measure correlating with lumbar vertebrae's microarchitecture and is measured in a subset. (bmj.com)
  • As a result, it is considered to be a textural index rather than a direct physical measurement of bone microarchitecture (Silva BC et al 2014). (cdc.gov)
  • Depression, anxiety, and smoking are associated with lower bone mineral density (BMD) in adults, but these factors have not previously been studied during adolescence, when more than 50% of bone accrual occurs. (scienceblog.com)
  • In 2013, TBS software (Med-Imap SA TBS Calculator version 2.1.0.2) was used to estimate the trabecular bone scores for individual lumbar vertebra (L1-L4), as well as an overall TBS score for the total lumbar spine, in adults aged 20 years and older with nonmissing body mass index (BMI) data. (cdc.gov)
  • Osteoporosis or low bone mass in older adults: United States, 2017-2018. (cdc.gov)
  • Matrix extracellular phosphoglycoprotein (MEPE) [ 12 ] and frizzled related protein-4 (FRP-4) have emerged as candidate mediators of the bone-renal pathophysiology as well but are rarely described in literature, so far [ 11 , 12 ]. (hindawi.com)
  • This is particularly important at menopause, where the drop in estrogen increases the turnover rate and hence the rate of loss of bone. (anh-usa.org)
  • This mainly occurs via secondary hyperparathyroidism, leading to excessive bone remodelling and ultimately to bone weakening, which in turn increases fragility fracture risk. (hindawi.com)
  • They begin at the start of the lumbar curve (ie, the thoracolumbar junction) and extend to the sacrum. (medscape.com)
  • Vitamins K2 and D3 have a protective effect on prednisolone-induced loss of bone mineral density in the lumbar spine. (greenmedinfo.com)
  • Osteoporosis is characterized by compromised bone strength due to loss of bone mass and deterioration of bone quality, resulting in increased fracture risk. (ajmc.com)
  • To evaluate the bone mineral status of children being treated for X-linked hypophosphatemia, including potential differences between cortical bone in the radial diaphysis and combined cortical and trabecular bone in the lumbar spine. (northwestern.edu)
  • A fragility fracture is one that occurs after less trauma than might be expected to fracture a normal bone. (msdmanuals.com)
  • After cessation of growth hormone (GH) due to adult height attainment, bone mineral apparent density (BMAD) of the lumbar spine deteriorates and there is a trend towards a deterioration of bone mineral density (BMD) of the total body in males," Dr. Carolina C. J. Smeets from Erasmus University Medical Center, Rotterdam, The Netherlands told Reuters Health. (medscape.com)
  • The urine can be sampled for markers of increased bone turnover, which occur in persons with osteoporosis. (medscape.com)
  • Overall, HR-pQCT, DXA bone parameters and bone turnover markers remained unaffected. (frontiersin.org)
  • We identify plausible genetic correlations between MPB and multiple sex-limited markers of earlier puberty, increased bone mineral density ( r g = 0.15) and pancreatic β-cell function ( r g = 0.12). (nature.com)
  • 25-OHD level was measured by radioimmunoassay, and bone metabolic status including bone mineral density and bone turnover markers was also measured. (vitamindwiki.com)
  • No such correlations were observed with bone marrow markers. (bvsalud.org)
  • Discrepancies between peripheral blood and bone marrow markers emphasize the need for further exploration. (bvsalud.org)
  • Participants who spent more time moving their bodies had higher bone mineral density and lower total fat percentage. (saveourbones.com)
  • More physically active participants had higher bone mineral density and lower fat percentage. (saveourbones.com)
  • Compared to an earlier investigation with older specimens (reported at last year's conference), these young specimens had higher bone mineral content and density and longer fatigue life compared to the older sample (which averaged 80 years of age). (cdc.gov)
  • Men have higher bone mass than women. (msdmanuals.com)
  • The main reason for screw loosening is that pedicle screws are mainly fixed by cancelous bone, and it is often compromised in patients with osteoporosis. (biomedcentral.com)
  • Fatigue failure of lumbar motion segments in a sample of working age specimens. (cdc.gov)
  • Bone mineral density for these specimens was 1.00 gram per square centimeter (+/- 0.25), and the average bone mineral content was 30.7 g (+/- 11.1). (cdc.gov)
  • This is most likely in spongy (trabecular) bone, and when this happens the osteoblasts can not fill that pit with the saturated solution that deposits the new bone. (anh-usa.org)
  • A 49-year-old woman from the state of Illinois, U.S.A., was referred for chronic, widespread, musculoskeletal aches and pains accompanying dense bones. (fluoridealert.org)
  • Briefly, patients with iRMDs were prospectively enrolled and assessed with DXA scans, laboratory testing, and bone-health-related questionnaires since 2015. (bmj.com)
  • A study of 9,787 Americans assessed the impact of sedentary activity and physical activity on bone mineral density and body fat percentage using questionnaires and DEXA scans. (saveourbones.com)
  • Beginning in 2005, DXA scans of the lumbar spine have been administered in the NHANES mobile examination center (MEC). (cdc.gov)
  • It is measured by evaluating gray-level variations in the pixels of an anterior-posterior lumbar spine DXA scan. (cdc.gov)
  • The patient subsequently underwent a posterior arthrodesis with iliac crest bone graft and transpedicular screw placement. (medscape.com)
  • In a recent study, the effects on bone mass did not differ between groups of infants with different levels of vitamin D supplementation. (contemporarypediatrics.com)
  • A higher dose of vitamin D supplementation is not associated with advantages in bone mass for infants born with 25-hydroxyvitamin D (25[OH]D) concentrations less than 50 nmol/L, according to a recent study. (contemporarypediatrics.com)
  • However, it is unknown if infants born with low 25(OH)D have compromised bone mineral content (BMC), or if increased vitamin D dosage is needed for improved vitamin d stores and bone health. (contemporarypediatrics.com)
  • This showed an absence of effects from vitamin D supplementation on bone mass in infants born with 25(OH)D concentrations under 50 nmol/L. (contemporarypediatrics.com)
  • Matrix Gla-protein (MGP), a vitamin K-dependent protein present in vascular smooth muscle, bone, and cartilage, is the focus of considerable scientific research because it might help reduce abnormal calcification [ 9 ]. (nih.gov)
  • Osteocalcin is another vitamin K-dependent protein that is present in bone and may be involved in bone mineralization or turnover [ 5 ]. (nih.gov)
  • From there, vitamin K is incorporated into chylomicrons, secreted into the lymphatic capillaries, transported to the liver, and repackaged into very low-density lipoproteins [ 2 , 10 ]. (nih.gov)
  • The study authors also suggested that causes of bone loss and increased fat could include higher parathyroid hormone production and a lack of Vitamin D production due to sedentary behavior and indoor activities. (saveourbones.com)
  • Vitamin D inadequacy is highly prevalent worldwide [ 1 ] and has well-known direct and deleterious consequences on bone health. (hindawi.com)
  • Osteoblasts (cells that make the organic matrix of bone and then mineralize bone) and osteoclasts (cells that resorb bone) are regulated by parathyroid hormone (PTH), calcitonin , estrogen , vitamin D , various cytokines, and other local factors such as prostaglandins. (msdmanuals.com)
  • In adolescent bone sarcoma patients, bone mass acquisition is potentially compromised at a time in which it should be at a maximum. (cun.es)
  • We found that the BMD of the lumbar spine of people taking bisphosphonates was 3.50% higher (2.90% to 4.10% higher) than in people who had no treatment. (cochrane.org)
  • Approximately three people (range 2 to 3) would need to be treated with bisphosphonates for 12 months for one person to see a minimally important difference in BMD at the lumbar spine. (cochrane.org)
  • Senior study author Dr Evangelos Terpos, of the National and Kapodistrian University of Athens, said: "Not only is denosumab associated with improved bone health and reduced pain, but its ease of administration may very well make this drug superior to bisphosphonates for the treatment of osteoporosis in patients with TDT and osteoporosis. (b-s-h.org.uk)
  • The added density caused by osteoporosis drugs like bisphosphonates happens by warping the bone remodeling process. (saveourbones.com)
  • Bone accrual trajectories from ages 11 to 19 were estimated for total-body bone mineral content (TB BMC) and lumbar spine and total hip bone mineral density (BMD). (scienceblog.com)
  • RÉSUMÉ Pour vérifier l'hypothèse selon laquelle les graisses localisées et non le poids corporel total ont un effet protecteur sur la densité minérale osseuse des femmes ménopausées, une étude transversale a été menée entre mars 2008 et juin 2009 sur 303 femmes ménopausées en bonne santé consultant le service de soins de l'ostéoporose à des fins de dépistage. (who.int)
  • nificance of individual coefficients in the en, bone mineral status is much more Daily routine calibration was done model was assessed by the Hosmer- closely associated with total body fat using the standard phantom supplied Lemeshow test for goodness of fit and [4] and in a multivariate model total fat by the manufacturer. (who.int)
  • While none of the control participants had low bone mass, it was detected in 6% of the participants with cow's milk allergy. (clinicaladvisor.com)
  • Less active participants had lower bone mineral density . (saveourbones.com)
  • The researchers found that sedentary participants had lower bone mineral density and higher fat percentage. (saveourbones.com)
  • severe chronic bone and joint pain, and kyphosis after consuming 1-2 gallons of brewed orange pekoe tea daily for more than three decades. (fluoridealert.org)
  • These phantoms contain materials that represent a number of different equivalent bone mineral densities. (lilesnet.com)
  • As noted by a team of Chinese researchers who have carefully studied the impacts of tea intake on bone health, "it is certain that some heavy-tea drinkers suffering from fluorosis from tea-drinking might not be diagnosed. (fluoridealert.org)