• Typical examples of risk estimation include use of Japanese atomic bomb survivor data to estimate future risk from radiation-related cancer among American patients receiving multiple computed tomography scans, persons affected by radioactive fallout, or persons whose livelihoods involve some radiation exposure, such as x-ray technicians, interventional radiologists, or shipyard workers. (nih.gov)
  • In early 2011 NIOSH posted a blog entry commenting on the preliminary results from the National Lung Screening Trial (NLST), funded by the National Cancer Institute, that found a 20.3% reduction in deaths from lung cancer among current or former heavy smokers who were screened with low-dose helical computed tomography (CT) versus those screened by chest X-ray (CXR). (cdc.gov)
  • The method could clearly identify abnormalities typical of the illness and involves a significantly lower radiation dose than the computed tomography methods currently in use. (tum.de)
  • The highlighted topics include basic aspects of biological dosimetry and its limitations in the range of low radiation doses, and main patterns of in vivo induction of radiation biomarkers in clinical exposure scenarios, occurring in X-ray diagnostics, computed tomography , interventional radiology , low dose radiotherapy , and nuclear medicine (internally administered 131I and other radiopharmaceuticals ). (bvsalud.org)
  • If you've smoked at least a pack a day for 20 years and have COPD, an annual chest computed tomography (CT) scan can lower your risk of death from lung cancer. (ucsd.edu)
  • Patients want to know if radiation from mammograms , bone density tests , computed tomography (CT) scans, and so forth will increase their risk of developing cancer. (harvard.edu)
  • Xstrahl, a global leader in the delivery of superficial radiation therapy devices and preclinical radiation research systems, will demonstrate Radiant Aura, a new low-dose, X-ray based, dual modality radiation therapy for treating non-melanoma skin cancers (NMSC) and keloid scarring at the American Society for Therapeutic Radiology and Oncology (ASTRO) Annual Meeting in San Diego, CA, October 1-3, 2023, booth #2216. (xstrahl.com)
  • The NCCN Radiation Therapy Compendium™ is reviewed on a continual basis to ensure that the recommendations take into account the most current evidence, and is recognized by public and is a reference for radiation oncology coverage policy. (nccn.org)
  • Most interesthasbeeninstereotacticradiation(Muranoetal) butfocal therapy maynot apply well forbreastCNScarcinomatosis inpatientsoftenpreviouslytreated  Low-dose radiationhasbeenusedtopotentiate systemicchemotherapyinheadandneck cancer (Arnoldetal) Hypothesis: Low-dose radiationpriortointrathecal trastuzumabmayinduce HER2expressionand improve treatmentefficacyinwomenwithHER2+CNScarcinomatosis. (slideshare.net)
  • Nowadays medical care extensively uses ionising radiation for diagnostic and therapy. (ises-europe.org)
  • It should involve radiology and therapy equipment manufacturers or their associations, European associations of researchers in this field, organisations having a regulatory mandate for radiation protection research from Member States or EU bodies and universities and hospitals. (ises-europe.org)
  • This form of internal radiation therapy allows for more targeted radiation treatment, designed to reduce the size of tumors and kill cancer cells. (cancercenter.com)
  • This internal radiation therapy delivers a high-dose of radiation from implants placed close to, or inside, the tumor(s) in the body in a short burst lasting a few minutes. (cancercenter.com)
  • With IORT, which stands for interoperative radiation therapy, a radiation oncologist delivers a large dose of radiation in a single treatment session during a surgical procedure. (cancercenter.com)
  • In advanced HCC, dual-energy CT may detect the effects of therapy at lower radiation dose than liver perfusion CT, researchers in France say. (mdct.net)
  • According to a French study , in advanced hepatocellular carcinoma, therapy-induced changes in morphology and perfusion may be assessed from iodine concentrations measured with dual-energy CT, possibly eliminating the need for liver perfusion CT and its higher radiation dose. (mdct.net)
  • Xstrahl attends regional conferences to meet with clinicians and discuss radiation therapy Radiation therapy is a critical treatment option for managing cancer, where X-ray therapy is often the treatment option for skin cancer. (xstrahl.com)
  • Twenty-one patients who underwent androgen ablation between June 1991 and December 1995 in addition to combined-modality radiation therapy qualified as high risk, as did 77 patients who underwent combined-radiation therapy only. (elsevierpure.com)
  • Conclusion: Longer follow-up with larger patient numbers is needed to define the role of adjuvant androgen ablation combined with radiation therapy. (elsevierpure.com)
  • The external beam radiation therapy is the largest segment of the Radiotherapy market followed by internal beam radio therapy. (medgadget.com)
  • On the basis of technology, it can be categorized to external beam radiation therapy, internal beam radio therapy and Systemic Radiation Therapy. (medgadget.com)
  • Because radiation is most harmful to quickly growing cells, radiation therapy damages cancer cells more easily than normal cells. (medlineplus.gov)
  • Intraoperative radiation therapy is delivered in the operating room while you are asleep after breast tissue is removed. (medlineplus.gov)
  • The radiation therapy is given after lumpectomy (also called) a partial mastectomy. (medlineplus.gov)
  • This approach is called adjuvant (additional) radiation therapy because it is adding a treatment beyond surgery. (medlineplus.gov)
  • Because these techniques are not as well studied as whole-breast radiation therapy, there is not full agreement about who is most likely to benefit. (medlineplus.gov)
  • Over half of cancer patients undergo radiation therapy (RT). (nature.com)
  • Radiation therapy , also called X-ray therapy, uses high levels of radiation to kill prostate cancer cells or keep them from growing and dividing while minimizing damage to healthy cells. (webmd.com)
  • Who Might Benefit From Radiation Therapy? (webmd.com)
  • Your doctor might recommend radiation therapy in several situations. (webmd.com)
  • Radiation, along with hormone therapy, might also be part of your first cancer treatment if the disease has spread beyond your prostate into nearby tissues. (webmd.com)
  • If you get surgery for prostate cancer, your doctor might recommend you get radiation therapy afterward, too. (webmd.com)
  • If you get external radiation therapy, you'll need to get regular sessions (generally 5 days per week) during a period of about 5 to 8 weeks. (webmd.com)
  • Good nutrition is an important part of recovering from the side effects of radiation therapy. (webmd.com)
  • They can help make sure that you're getting enough nutrition during your radiation therapy. (webmd.com)
  • The NCCN Radiation Therapy Compendium™ includes information designed to support clinical decision-making around the use of radiation therapy in patients with cancer and is based directly on the NCCN Guidelines. (nccn.org)
  • The NCCN Radiation Therapy Compendium™ is accessible through a subscription-based searchable user interface and includes a full complement of radiation therapy recommendations found in the current Guidelines. (nccn.org)
  • Introduction: Proton radiation therapy (PT) has become a treatment option alongside photon therapy (XRT) for lower-grade gliomas (LGG). (lu.se)
  • Background Preclinical evidence suggests that low-dose radiation may overcome the inhibitory effects of the tumor stroma and improve a tumor's response to immunotherapy, when combined with high-dose radiation to another tumor. (bmj.com)
  • Figure 2: BCC-like tumor average cross-sectional area increases with duration of UV exposure and dose of IR exposure. (nature.com)
  • IORT delivers a concentrated dose of radiation to a tumor site immediately after a tumor is removed, helping to destroy the microscopic tumor cells that may be left behind. (cancercenter.com)
  • The patients receiving PT were younger, had a lower tumor grade, more oligodendrogliomas and received a lower mean brain and brainstem dose. (lu.se)
  • This represents good evidence that we live with a partial radiation deficiency and that greater exposure to radiation would improve our health, a notion supported by 130 on the health of people living in parts of the world with higher background levels of ionizing radiation than average. (scienceblog.com)
  • 2] National Research Council of the National Academies, Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation. (cdc.gov)
  • Health risks from exposure to low levels of ionizing radiation: BEIR VII, Phase 2 [online]. (cdc.gov)
  • ICLDRR's main focus is to contribute to clarifying whether low and very low doses of ionizing radiation increase the risk of cancer. (wikipedia.org)
  • To that end, the ICLDRR has assembled and analysed virtually all published data on cancer induction in laboratory animals by low doses of ionizing radiation, and published initial findings at specialized international conferences, since 1998. (wikipedia.org)
  • In high doses it is certainly lethal and chronic exposure is linked to the development of cancer. (scienceblog.com)
  • Today, radioactivity is used in targeted therapies for certain forms of cancer, however, the use of radiation sources for treating other diseases is not currently recognized by the medical profession. (scienceblog.com)
  • His own research suggests that radiation exposure can minimize infectious disease, reduce the incidence of cancer in the young, and substantially increase average lifespan. (scienceblog.com)
  • Studies on the growth, average lifespan, and decreased cancer mortality rates of humans exposed to low-dose irradiation show improved health, explains Luckey. (scienceblog.com)
  • Ionizing radiation is a known and well-quantified human cancer risk factor, based on a remarkably consistent body of information from epidemiological studies of exposed populations. (nih.gov)
  • As a result, exposure to ionizing radiation (which includes x-rays, gamma rays, alpha and beta particles) can increase a person's risk to developing cancer. (radiationsafety.ca)
  • But ionizing radiation is used to create images of internal organs of the human body and to treat cancer. (radiationsafety.ca)
  • Last week, the U.S. Preventative Services Task Force made a draft recommendation that people who are at a high risk for developing lung cancer should receive annual low-dose CT screenings. (radiationsafety.ca)
  • Scholars@Duke publication: Low-dose fractionated radiation potentiates the effects of cisplatin independent of the hyper-radiation sensitivity in human lung cancer cells. (duke.edu)
  • In this study, the role of hyper-radiation sensitivity (HRS) in potentiating the effects of cisplatin by low-dose fractionated radiation (LDFRT) was evaluated in four human non-small cell lung cancer cell lines. (duke.edu)
  • These findings indicate that chemopotentiation by LDFRT is correlated more with the intrinsic radiation sensitivity of the non-small lung cancer cells than the HRS phenomenon whereas the mode of cell killing is both through apoptosis and clonogenic inhibition. (duke.edu)
  • For instance, the radiation may be placed in the rectum to treat rectal cancer. (cancercenter.com)
  • These implants remain in place for a set period of time depending on the cancer type, other treatments, the type of radiation source, the cancer's location and the patient's overall health status. (cancercenter.com)
  • The National Lung Screening Trial (NLST) 2 was a national randomized controlled trial launched by the National Cancer Institute (NCI) in 2002 to determine whether annual screening with low-dose helical CT would lead to earlier detection and reduced mortality from lung cancer relative to screening with CXR. (cdc.gov)
  • In this trial 53,454 participants at high risk for lung cancer-current and former heavy smokers of at least 30 pack-years between 55 and 74 years of age-were randomly assigned to receive low-dose helical CT or chest x-ray screenings once a year for three years, and then followed for 3.5 additional years with no further screening. (cdc.gov)
  • During the screening phase of the trial, 39.1% of the participants in the low-dose helical CT group and 16% of the participants in the chest X-ray group had at least one positive screening result, i.e., a finding suggestive of lung cancer. (cdc.gov)
  • Upon follow-up, 96.4% of the "positive" low-dose CT tests and 94.5% of the "positive" X-ray tests turned out to be false positives, meaning that the positive finding did not prove to be lung cancer. (cdc.gov)
  • Lung cancer was confirmed in 3.6% of the positive screenings in the low-dose CT group and in 5.5% of the positive screenings in the X-ray group. (cdc.gov)
  • Among those who did have complications, 16 participants screened with low-dose helical CT (10 of whom had lung cancer) and 10 X-ray participants (all with lung cancer) died within 60 days of a follow-up invasive diagnostic procedure. (cdc.gov)
  • Lung cancer incidence per 100,000 person-years was 645 (1,060 cancers) in the low-dose helical CT group and 572 (941 cancers) in the chest X-ray group. (cdc.gov)
  • All-cause mortality (deaths due to any cause, including lung cancer) was reduced by 6.7% for those participants who underwent low-dose helical CTs compared to those who received chest X-rays. (cdc.gov)
  • the NLST is the first randomized trial to show a significant reduction in mortality from lung cancer with low-dose CT screening. (cdc.gov)
  • It can be the first treatment for cancer that hasn't spread outside your prostate gland and is "low grade. (webmd.com)
  • The lower the grade, the more normal-looking your cancer cells are - and, in general, the more likely your cancer is slow-growing. (webmd.com)
  • If you have advanced prostate cancer, radiation could help keep the disease under control for as long as possible. (webmd.com)
  • Cytogenetic assays appeared to be a valuable tool for individualized quantifying radiation effects in patients , with high capability for assessing genotoxicity of various medical exposure modalities and providing meaningful radiation dose estimates for prognoses of radiation -related cancer risk . (bvsalud.org)
  • Screening with a low-dose CT scan can identify cancer early and save your life. (nationaljewish.org)
  • The benefits of these tests, when they're appropriate, far outweigh any radiation-associated cancer risks, and the risk from a single CT scan or nuclear imaging test is quite small. (harvard.edu)
  • But we have no clinical trials to guide our thinking about cancer risk from medical radiation in healthy adults. (harvard.edu)
  • These studies show a slightly but significantly increased risk of cancer in those exposed to the blasts, including a group of 25,000 Hiroshima survivors who received less than 50 mSv of radiation - an amount you might get from three or more CT scans. (harvard.edu)
  • We conclude that long-term exposure to low doses of [ionizing radiation] can induce formation of micronuclei in the PBL of interventional radiologists," the group wrote. (auntminnie.com)
  • In order to determine which types of fatigue protocols are most likely to induce LFF, ten individuals participated in four different fatigue experiments which induced similar reductions in maximal force output as following: (1) 2-min intermittent high-frequency stimulation (40 Hz), (2) 4-min intermittent low-frequency stimulation (20 Hz), (3) sustained 100% maximal voluntary contraction (MVC), and (4) low-force voluntary contractions (20% MVC). (nih.gov)
  • In addition to cell cycle arrest, DNA repair or/and apoptosis, ionizing radiation can also induce premature senescence, which could lead to very different biological consequences depending on the cell type. (tmu.edu.tw)
  • The ICLDRR assembles all published data and conducts analyses concerning the effects of low doses of radiation on humans and in the environment. (wikipedia.org)
  • the evidence for a radiation deficiency in humans is compelling. (scienceblog.com)
  • Professor André Maïsseu, the journal's Editor-in-Chief, and President of the World Council of Nuclear Workers WONUC) says: "This is a very bright, interesting and important paper about the real effects of ionizing radiation - radioactivity - on humans, mammals and biotopes. (scienceblog.com)
  • A dose of 400 cGy (400 rads) is equivalent in heat to only 4.184 x 10^-3 joules per gram of tissue -- enough to provoke a mini-fever of 0.001 degree Centigrade -- yet 400 cGy of ionizing radiation to the whole body, acutely delivered, will kill about half the humans exposed to it. (ratical.org)
  • Previous attempts to characterise cardiovascular risks in cohorts suggests ionising radiation increases the risk of cardiovascular disease. (bmj.com)
  • As with any scan of this kind, you will be exposed to some radiation, which has the potential for health risks. (altonmemorialhospital.org)
  • From these potential exposure pathways, calculate both the radiation doses and risks associated with these exposures. (cdc.gov)
  • Because historical records were not maintained to today's standards, the Task 4 team performed independent reviews of environmental monitoring reports and existing data on releases and also used mathematical models to estimate the radiation doses and the associated risks (ChemRisk 1999a). (cdc.gov)
  • You may want to ask your healthcare provider about the amount of radiation used during the procedure and the risks related to your situation. (rochester.edu)
  • Most of what we know about the risks of ionizing radiation comes from long-term studies of people who survived the 1945 atomic bomb blasts at Hiroshima and Nagasaki. (harvard.edu)
  • ABSTRACT Previous studies have shown that physicians tend to underestimate the risks to patients of radiation exposure. (who.int)
  • It is important to remember that while in this case, the increased radiation dose is deemed to be appropriate, for other conditions the use of routine CT screening scans may not be justified. (radiationsafety.ca)
  • As CT scanning becomes more wide-spread, the propotion of X-ray dose exposure resulting from CT scans increases. (fujifilm.com)
  • What are low-radiation-dose CT lung scans? (altonmemorialhospital.org)
  • LDCT scans have a lower radiation dose than a chest X-ray or a standard CT scan. (altonmemorialhospital.org)
  • These low-dose CT scans minimize radiation exposure. (ucsd.edu)
  • For decades, we have been told that exposure to radiation is dangerous. (scienceblog.com)
  • Then, exposure to radiation, rather than being seen as hazardous, was considered a panacea for a wide variety of ailments from arthritis to consumption. (scienceblog.com)
  • The PT patients had a significantly better PFS and OS than the XRT patients (p =.025 and.035), but in multivariate analysis radiation modality was non-significant. (lu.se)
  • Low-dose hyper-radiosensitivity (HRS) is the phenomenon whereby cells exposed to radiation doses of less than ∼0.5 Gy exhibit increased cell killing relative to that predicted from back-extrapolating high-dose survival data using a linear-quadratic model. (xstrahl.com)
  • Luckey suggests that the medical use of small samples of partially shielded radioactive waste would provide a simple solution to radiation deficiency. (scienceblog.com)
  • A few days after placement, radiation in the form of tiny radioactive pellets can go into the channels, delivering radiation from inside the balloon. (medlineplus.gov)
  • Recommended threshold for relocating people (if projected dose from radioactive contamination is greater for the coming year, relocate). (cdc.gov)
  • To explain what ionizing radiation is, we will start with a discussion of atoms, how they come to be radioactive, and how they give off ionizing radiation. (cdc.gov)
  • Ionizing radiation is energy that is carried by several types of particles and rays given off by radioactive material, x ray machines, and fuel elements in nuclear reactors. (cdc.gov)
  • These radioactive materials can be temporary (removed after the proper dose is reached) or permanent. (webmd.com)
  • We're exposed to small doses of ionizing radiation from natural sources all the time - in particular, cosmic radiation, mainly from the sun, and radon, a radioactive gas that comes from the natural breakdown of uranium in soil, rock, water, and building materials. (harvard.edu)
  • In order to understand the basis of increased cellular lethality at low doses as well as the density-mediated suppression of HRS/IRR response, effect of low gamma radiation doses was studied using additional parameters including micronucleation, apoptosis induction and cell cycle progression delay in the absence and presence of inhibitors of gap junctional intercellular communication (GJIC) and NO signaling. (radioprotection.org)
  • Of the different types and sources of ionizing radiation, this profile will discuss the three main types: alpha, beta, and gamma radiation. (cdc.gov)
  • It should also provide recommendations on radiological protection for the development of new applications of radiation in medical care, per category and per procedure. (ises-europe.org)
  • For example, the Diagnostic reference level (DRL), which is a measure of the radiation dose for radiological diagnosis, has been introduced in many countries, defining standards to promote scanning at the lowest possible dose consistent with maintaining high image quality. (fujifilm.com)
  • Clinical Applications of Biological Dosimetry in Patients Exposed to Low Dose Radiation Due to Radiological, Imaging or Nuclear Medicine Procedures. (bvsalud.org)
  • Additionally, several specific issues, examined by biodosimetry techniques , are analysed, such as contrast media effect, radiation response in pediatric patients , impact of magnetic resonance imaging , evaluation of radioprotectors, detection of patients ' abnormal intrinsic radiosensitivity and dose estimation in persons involved in medical radiation incidents. (bvsalud.org)
  • We report here that Ptch +/- mice develop primordial follicular neoplasms resembling human trichoblastomas, and that exposure to ultraviolet radiation or ionizing radiation results in an increase in the number and size of these tumors and a shift in their histologic features so that they more closely resemble human basal cell carcinoma. (nature.com)
  • It does not tell you about non-ionizing radiation, such as microwaves, ultrasound, or ultraviolet radiation. (cdc.gov)
  • Water disinfection methods that can be applied in the field include use of heat, clarification, filtration, chemical disinfection, and ultraviolet radiation (UVR). (cdc.gov)
  • Recognition of O6MeG lesions by MGMT and mismatch repair proficiency may be a prerequisite for low-dose radiation hypersensitivity. (xstrahl.com)
  • RESULTS: The mean effective dose (HE) ranged from 0.31 to 2.75 mSv at 80 kVp, 0.69 to 6.29 mSv at 100 kVp, and 1.53 to 10.7 mSv at 120 kVp. (edu.au)
  • The estimation of the effective dose by Monte carlo simulation revealed lower median dose levels 1.72 (range 0.99-2.88) msv.mGy-1.cm-1 Conclusion: Cardiac high-pitch CTA on neonates with CHD can be performed safely and dose reducing protocols can be implemented without compromising image quality. (journalcra.com)
  • Effective dose equivalent and effective dose: Comparison for common projections in oral and maxillofacial radiology. (cdc.gov)
  • In the case of low-LET radiation, the initial charged particle creating the track is the electron itself. (ratical.org)
  • One need only consider the common fever in order to ponder the very high probability that the biological potency of ionizing radiation is related to its spatial concentration along tracks, rather than to its meager addition of energy to cells ( Go81 , pp.52-53). (ratical.org)
  • At low doses, biological reactions are unique and often unrelated to those that occur at high levels. (wsu.edu)
  • This review summarized current data on the use of biological dosimetry methods in patients undergoing various medical irradiations to low doses. (bvsalud.org)
  • These units, the ones most commonly used in comparing imaging procedures, take into account the biological effect of radiation, which varies with the type of radiation and the vulnerability of the affected body tissue. (harvard.edu)
  • Vieworks introduced three new radiation dose and image processing software technologies at RSNA 2023. (auntminnie.com)
  • When beliefs are abandoned and evidence from only whole body exposures to mammals is considered, it becomes obvious that increased ionizing radiation would provide abundant health," Luckey explains. (scienceblog.com)
  • The hugely influential linear-no-threshold model-which predicted acute exposure damage can be extrapolated linearly to low dose exposures-was flawed. (wsu.edu)
  • eye -lens absorbed dose from occupational radiation exposures was 55.7 mGy (interquartile range 23.6-69.0 mGy). (cdc.gov)
  • Our results suggest that there is excess risk for cataract associated with radiation exposure from low-dose and low dose-rate occupational exposures. (cdc.gov)
  • For internal cohort measures, the summary ERR/Sv for a lagged exposure of 10 years was 0.10 (95% CI 0.01 to 0.20) with low heterogeneity. (bmj.com)
  • Much is known about the effects of high doses of ionizing radiation exposure, but little is known about the effects of low doses of ionizing radiation over extended periods of time. (sc.edu)
  • However, statistical analyses showed that low-dose ionizing radiation exposure was not associated with significant effects on sex ratio, comet response, or PBMC concentration between control and contaminated areas for the studied voles. (sc.edu)
  • Ionizing radiation exposure of the population of the United States. (cdc.gov)
  • Ionising radiation is a human carcinogen, but the evidence is less clear that exposure to low-dose ionising radiation (LDIR) increases the risk of adverse cardiovascular outcomes. (bmj.com)
  • There is a growing recognition that exposure to low-dose ionising radiation (LDIR) may increase the risk of cardiovascular disease and reduce longevity. (bmj.com)
  • Together with natural radiation, medical applications are the main contributor to the exposure of the European population to ionising radiation. (ises-europe.org)
  • This action should add clarity on detriment from new medical applications of ionising radiation in view of their fast deployment. (ises-europe.org)
  • Prospective ECG-triggering is regarded as one of the most effective approaches for reduction of radiation dose to patients during coronary CT angiography (CCTA). (edu.au)
  • Twenty-six (of 155) patients received low-dose radiation (1-20 Gy total), either as scatter from high-dose radiation or from intentional treatment of a second isocenter with low-dose radiation, were evaluated for response. (bmj.com)
  • Results The 26 patients had a total of 83 lesions for comparison (38 receiving low-dose, 45 receiving no-dose). (bmj.com)
  • Thus, using data of patients in the medical sector together with radiation exposure records will improve knowledge. (ises-europe.org)
  • It offers a quicker, more effective type of radiation treatment for some patients than traditional radiation delivered in smaller doses over a longer period of time. (cancercenter.com)
  • Background: The use of CTA in patients with CHD has been limited by concerns about high radiation exposure. (journalcra.com)
  • [ 3 ] However, various technologies and techniques have made it possible to lower the dose to less than 5 mSv, and doses of less than 1 mSv are possible in some patients. (medscape.com)
  • The study revealed the necessity of further research , which might clarify medical radiation safety concerns for patients via using stringent biodosimetry methodology . (bvsalud.org)
  • Les pratiques des médecins en termes de fréquence d'utilisation des examens radiologiques routiniers et de discussion sur les risques avec leurs patients étaient aussi médiocres. (who.int)
  • As many of 40% of patients with a low clinical suspicion and a negative D-dimer result require no further evaluation. (medscape.com)
  • OBJECTIVE: This study aimed (1) to perform a systematic review on scanning parameters and contrast medium (CM) reduction methods used in prospectively ECG-triggered low tube voltage coronary CT angiography (CCTA), (2) to compare the achievable dose reduction and image quality, and (3) to propose appropriate scanning techniques and CM administration methods. (edu.au)
  • Advances in knowledge: The suggested appropriate scanning parameters and CM reduction methods can be used to help users in achieving diagnostic image quality with reduced radiation dose. (edu.au)
  • Radiation dose parameters were modified inorder to lower the effective radiation dose. (journalcra.com)
  • Thus, the aim of this study was to assess the diagnostic performance of panoramic radiomorphometric indices and parameters in detecting low bone density. (bvsalud.org)
  • In contrast to PMA that enhanced micronucleation and reduced irradiated cell survival at low doses, LNMMA inhibited the micronucleation and enhanced survival in the irradiated cells, indicating the role of nitrosative stress in low-dose sensitivity of cells. (radioprotection.org)
  • This action should take into account the gap analysis performed by MELODI, EURADOS and EURAMED, and address the key issue of individual sensitivity and susceptibility to radiation. (ises-europe.org)
  • However, little is known about the differences in sensitivity and specificity among these measurements for screening low bone mineral density (BMD). (bvsalud.org)
  • To correlate and compare precision, sensitivity and specificity of panoramic radiomorphometric indices and fractal dimension (FD) for screening low BMD (i.e. osteopenia and osteoporosis). (bvsalud.org)
  • In addition, sensitivity and specificity of MCI, MCW and FD were estimated for screening low BMD. (bvsalud.org)
  • FD and MCI presented a significant and relatively high sensitivity, whereas MCW presented a high specificity for screening low systemic BMD. (bvsalud.org)
  • Typical dose from a chest x-ray. (cdc.gov)
  • These factors include the dose (how much), the duration (how long), and the type of radiation. (cdc.gov)
  • This is an idea for a novel clinical trial using radiation to make trastuzumab more effective based upon that discussion. (slideshare.net)
  • Radiation dosimetric biomarkers have found applications beyond radiation protection area and now are actively introduced into clinical practice. (bvsalud.org)
  • Evidence suggests that low dose exposure increases the number and activity of the immune system's white blood cells, boosts cytocrine and enzyme activity, and increases antibody production and so reduces the incidence of infection, assists in wound healing, and protects us from exposure to high doses of radiation. (scienceblog.com)
  • Dose from high altitude solar and cosmic radiation during a flight from New York City to Los Angeles. (cdc.gov)
  • In addition to solar and cosmic rays that are hazardous to astronauts' health, there is also ionizing radiation that threatens their electronic equipment. (universetoday.com)
  • Conclusions Low-dose radiation may increase systemic response rates of metastatic disease treated with high-dose radiation and immunotherapy. (bmj.com)
  • But many experts are concerned about an explosion in the use of higher radiation-dose tests, such as CT and nuclear imaging. (harvard.edu)
  • To perform a systematic review of the radiation dose and diagnostic accuracy of prospective versus retrospective ECG-gated multislice CT coronary angiography. (edu.au)
  • Port films don't provide diagnostic information, so radiation therapists can't learn about your progress from them. (webmd.com)
  • By contrast, for low-LET radiations such as X-rays and beta particles, the minimal unit is the primary ionization track left by a single high-speed electron. (ratical.org)
  • Similar vessel contrast enhancement to 120 kVp could be obtained by applying iodine delivery rate (IDR) of 1.35 to 1.45 gs-1 with total iodine dose (TID) of between 10.9 and 16.2 g at 80 kVp, and IDR of 1.08 to 1.70 gs-1 with TID of between 18.9 and 20.9 g at 100 kVp. (edu.au)
  • To reduce the Contrast Media Nephropathy (CIN) risk, efforts have been made to reduce the amount of contrast media used during low tube voltage scanning. (fujifilm.com)
  • Intelli IPV achieves an image texture similar to FBP images by making the NPS (noise power spectrum) close to that of the FBP, as well as improving the low contrast detectability by up to 2 times. (fujifilm.com)
  • Achieves image noise reduction up to 90%, radiation dose reduction up to 83%, and improves low contrast detection capability up to 2 times. (fujifilm.com)
  • Lower-extremity venogram shows outlining of an acute deep venous thrombosis in the popliteal vein with contrast enhancement. (medscape.com)
  • We show in this report that low-dose radiation-induced senescent stromal fibroblasts stimulate proliferation of cocultured breast carcinoma cells. (tmu.edu.tw)
  • The low dose of 20cGy induced significant micronucleation in cells, and inhibition of GJIC by PMA (5nM) significantly enhanced this radiation-induced micronucleation in high density cultures. (radioprotection.org)
  • On the other hand, the NOS inhibitor LNMMA reduced micronucleation induced at 20cGy, and also significantly mitigated the PMA-induced enhancement of radiation-induced micronucleation. (radioprotection.org)
  • In this study, inhibition of GJIC significantly enhanced low dose lethality in the high density tumour cell cultures, whereas NOS inhibition reversed this effect. (radioprotection.org)
  • Recent-generation CT scanner technology significantly reduces radiation exposure compared with older technology. (journalcra.com)
  • By implementing low dose radiation protocols, Case specific protocols, the radiation dose can be significantly reduced. (journalcra.com)
  • Their results have been used in support of the radiation hormesis hypothesis, wherein low-dose radiation may actually be beneficial for health. (wikipedia.org)
  • However, they noted that such damage from low-dose radiation in other radiology workers has been associated with malignancies in previous research. (auntminnie.com)
  • Long-term exposure to low-dose radiation can cause DNA damage to lymphocyte cells in interventional radiologists - yet importantly, the doctors are likely not vulnerable to an increased risk of leukemia, according to researchers in Slovakia. (auntminnie.com)
  • Using advanced genetic imaging techniques, the researchers analyzed blood samples from 12 interventional radiologists working in six various hospitals in Slovakia and 14 controls who worked in other hospital departments without radiation exposure. (auntminnie.com)
  • This study provides a detailed characterization of the dose-dependent impact of ionizing radiation on skin cells (45, 60, or 80 grays). (mdpi.com)
  • This chapter and the two other "auxiliary chapters" (Chapters 20 and 21 ) provide the support for certain points used in the proof that no safe dose of low-LET ionizing radiation exists -- either for acute exposure or for slow exposure -- with respect to human carcinogenesis. (ratical.org)
  • Lowest dose that could cause acute radiation syndrome. (cdc.gov)
  • Acute radiation syndrome: A fact sheet for physicians [online]. (cdc.gov)
  • Fourteen and 10 studies reporting external radiation doses were included in meta-analyses using SMR and ERR/Sv, respectively. (bmj.com)
  • Radiation can be given from a machine outside the body and directed at the prostate (external radiation). (webmd.com)
  • Occupational radiation exposure and risk of cataract incidence in a cohort of US radiologic technologists. (cdc.gov)
  • In terms of incidence, lower-extremity DVT is the most common venous thrombosis, with a prevalence of 1 case per 1000 population. (medscape.com)
  • In a comparison of prospectively gated 64- and 256-slice CT scanning, the 256-slice scan provided better and more stable image quality, at equivalent effective radiation dose. (medscape.com)
  • Dose received during a typical CT (Computerized Tomography) scan. (cdc.gov)
  • The test typically measures the bone density of the bones of the spine, lower arm, and hip. (rochester.edu)
  • A T-score of 1.1 to 2.4 SD below the young adult mean (-1.1 to -2.4 SD) indicates low bone mass. (rochester.edu)
  • Bone densitometry testing uses a low dose of radiation. (rochester.edu)
  • A diffusion-based deep learning model can help recover bone microstructure data from low-resolution CT images of the proximal femur. (auntminnie.com)
  • Researchers applied advances in instrumentation and molecular biology from the Human Genome Project and developed new technologies, like the microbeam, to examine cellular response to low dose radiation. (wsu.edu)
  • As we examine what is going on at the cellular level when tissue is exposed to low-LET exposure, it will become evident that the biologically important question for settling the threshold issue is not "What human studies exist at the lowest conceivable doses? (ratical.org)
  • The International Centre for Low Dose Radiation Research (ICLDRR) was established at the University of Ottawa, in 1997, with national and international support. (wikipedia.org)
  • Luckey hopes to change that viewpoint and argues that more than 3000 scientific papers in the research literature point to low doses of radiation as being beneficial in human health. (scienceblog.com)
  • Findings from the U.S. Department of Energy's new low dose radiation research program were startling. (wsu.edu)
  • In 1998, Dr. Brooks became Chief Scientist of the U.S. Department of Energy's (DOE's) new Low Dose Radiation Research Program. (wsu.edu)
  • Antone L. Brooks , Research Professor Emeritus at Washington State University Tri-Cities, holds a Master of Radiation Ecology and a Ph.D. in Physical Biology. (wsu.edu)
  • Radiation Research , 172 (3), 306-313. (tmu.edu.tw)
  • In the low-dose CT group, 649 cancers were diagnosed after a positive screening test, 44 after a negative screening test, and 367 among participants who either missed the screening or received the diagnosis after their trial screening phase was over. (cdc.gov)
  • We've long known that children and teens who receive high doses of radiation to treat lymphoma or other cancers are more likely to develop additional cancers later in life. (harvard.edu)
  • Measures are being taken worldwide to mitigate the exposed dose as the number of examinations increases. (fujifilm.com)
  • However, low-tube-voltage scanning increases image noise and the choice of exposure factors become more crucial. (fujifilm.com)
  • Iterative processing Intelli IPV maintains normal image texture, even at a high dose reduction ratio, as well as reducing the noise, resulting in improved visibility. (fujifilm.com)
  • Cervical spine injuries in children most commonly involve the upper spine, but complete lesions of the cord are associated more frequently with lower spine injuries. (medscape.com)
  • The average dose given to low-dose lesions was 7.3 Gy (1.1-19.4 Gy), and the average time to response was 56 days. (bmj.com)
  • Twenty-two out of 38 (58%) low-dose lesions met the PR/CR criteria for RECIST compared with 8 out of 45 (18%) no-dose lesions ( P = 0.0001). (bmj.com)
  • Conversely, two (4%) of the no-dose lesions responded without a corresponding response in their low-dose lesion ( P = 0.0004). (bmj.com)
  • In the cells irradiated at low density, U87 cell line has shown a highly distinguishable HRS/IRR response (Chandna et al, Radiat Res, 157, 516-525, 2002), which was mitigated at higher density. (radioprotection.org)
  • Excluding H-157 cells, the CER by LDFRT was inversely proportional to radioresistance [(determined by D(0), the dose to reduce survival by 67% from any point on the linear portion of the survival curve or surviving fraction (SF) at 2 Gy (SF(2))] of the cells. (duke.edu)
  • In addition, "hit theory," the idea that radiation only affected cells it directly traversed, yielded to a new "bystander theory," which hypothesizes that cells communicate with each other and a dose to one affects the cells around it. (wsu.edu)
  • It was expected that voles from contaminated areas would have higher male:female sex ratios, greater DNA damage as assessed through a greater proportion of cells responding to the procedure, the comet assay, and lower peripheral blood mononuclear cell (PBMC) concentrations on slide areas compared to voles from control sites. (sc.edu)
  • The elevated proliferation of breast carcinoma cells correlates with resistance to radiation as well as to adriamycin. (tmu.edu.tw)
  • We therefore hypothesized that the response of cells to low doses of radiation is dependent on the expression status of MGMT and MMR proteins. (xstrahl.com)
  • Dose that causes damage to blood cells. (cdc.gov)
  • Ionizing radiation can damage DNA, and although your cells repair most of the damage, they sometimes do the job imperfectly, leaving small areas of "misrepair. (harvard.edu)