Loss of tumor tumor suppressor proteins. Medical search. Frequent questions

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Anatomy15

Cell Line, Tumor Cell Line Abducens Nerve Tumor Cells, Cultured Cells, Cultured Fibroblasts HeLa Cells Cell Nucleus HCT116 Cells Cell Line, Transformed NIH 3T3 Cells COS Cells Epithelial Cells Cytoplasm HEK293 Cells

Organisms8

Mice, Nude Mice, Inbred C57BL Mice, Knockout Mice, Inbred BALB C Mice, Transgenic Mice, SCID Adenoviridae Papillomaviridae

Diseases41

Cell Transformation, Neoplastic Neoplasms Wilms Tumor Neoplasms, Experimental Kidney Neoplasms Brain Neoplasms Carcinoid Tumor Adenocarcinoma Breast Neoplasms Neuroendocrine Tumors Osteosarcoma Neoplasm Metastasis Liver Neoplasms Mammary Neoplasms, Experimental Carcinoma, Renal Cell Colonic Neoplasms Skin Neoplasms Neovascularization, Pathologic Carcinoma, Squamous Cell Disease Progression Neurofibromatosis 2 Carcinoma, Hepatocellular Ovarian Neoplasms Glioblastoma Glioma Lung Neoplasms von Hippel-Lindau Disease Retinoblastoma Gastrointestinal Stromal Tumors Pancreatic Neoplasms Fibrosarcoma Rhabdoid Tumor Disease Models, Animal Mammary Neoplasms, Animal Neuroblastoma Carcinoma, Ehrlich Tumor Sarcoma, Experimental Melanoma, Experimental Astrocytoma Bone Neoplasms Adenoma

Chemicals and Drugs90

Tumor Suppressor Protein p53 Tumor Suppressor Proteins Von Hippel-Lindau Tumor Suppressor Protein Tumor Suppressor Protein p14ARF Retinoblastoma Protein Proto-Oncogene Proteins c-mdm2 Tumor Markers, Biological Nuclear Proteins Neurofibromin 2 DNA-Binding Proteins Adenomatous Polyposis Coli Protein Transcription Factors Tumor Necrosis Factor-alpha Cyclin-Dependent Kinase Inhibitor p16 Proto-Oncogene Proteins Ubiquitin-Protein Ligases Neoplasm Proteins Cyclin-Dependent Kinase Inhibitor p21 Cell Cycle Proteins RNA, Messenger Cyclins Ligases Repressor Proteins E2F Transcription Factors Proteins Protein-Serine-Threonine Kinases RNA, Small Interfering Carrier Proteins DNA, Neoplasm E2F1 Transcription Factor Recombinant Fusion Proteins Suppressor of Cytokine Signaling Proteins WT1 Proteins Oncogene Proteins, Viral Transcription Factor DP1 Papillomavirus E7 Proteins Trans-Activators DNA Primers Antigens, CD2 Cyclin-Dependent Kinase Inhibitor Proteins Membrane Proteins Hypoxia-Inducible Factor 1, alpha Subunit Recombinant Proteins Retinoblastoma-Like Protein p107 Proteasome Endopeptidase Complex DNA Intracellular Signaling Peptides and Proteins Apoptosis Regulatory Proteins Cyclin-Dependent Kinases Antigens, Polyomavirus Transforming Ubiquitin Phosphoric Monoester Hydrolases Retinoblastoma-Like Protein p130 beta Catenin Phosphoproteins Cytoskeletal Proteins RNA, Neoplasm Neurofibromin 1 Adaptor Proteins, Signal Transducing Antineoplastic Agents Adenovirus E1A Proteins BRCA1 Protein Drosophila Proteins Proto-Oncogene Proteins c-myc Ubiquitins DNA, Complementary Antigens, Neoplasm MicroRNAs Luciferases Antibodies, Monoclonal Proto-Oncogene Proteins c-bcl-2 Adenovirus E1B Proteins Protein Isoforms Cyclin-Dependent Kinase 4 Carcinogens Oncogene Proteins Cyclin-Dependent Kinase Inhibitor p27 Suppressor Factors, Immunologic Hypoxia-Inducible Factor 1 Adenovirus E4 Proteins Proto-Oncogene Proteins c-akt Cyclin D1 Enzyme Inhibitors Antigens, Viral, Tumor bcl-2-Associated X Protein Cadherins Serine Cyclin-Dependent Kinase 2 Cysteine Endopeptidases Multiprotein Complexes

Analytical, Diagnostic and Therapeutic Techniques and Equipment32

Transfection Tumor Burden Blotting, Western Neoplasms, Experimental Reverse Transcriptase Polymerase Chain Reaction Immunohistochemistry Transplantation, Heterologous Models, Biological Mammary Neoplasms, Experimental Polymerase Chain Reaction Xenograft Model Antitumor Assays Immunoblotting Flow Cytometry Gene Expression Profiling Precipitin Tests Immunoprecipitation Neoplasm Transplantation Neoplasm Staging DNA Mutational Analysis Immunoenzyme Techniques Two-Hybrid System Techniques Oligonucleotide Array Sequence Analysis Disease Models, Animal Microscopy, Fluorescence Cloning, Molecular Chromosome Mapping Fluorescent Antibody Technique Tumor Stem Cell Assay Chromatin Immunoprecipitation Sarcoma, Experimental Melanoma, Experimental Blotting, Northern

Phenomena and Processes70

Genes, Tumor Suppressor Mutation Genes, p53 Gene Expression Regulation, Neoplastic Apoptosis Protein Binding Transfection Cell Cycle Cell Proliferation Signal Transduction Base Sequence Promoter Regions, Genetic Cell Division Genes, Suppressor Amino Acid Sequence Phosphorylation DNA Damage Transcription, Genetic Down-Regulation Transcriptional Activation Protein Structure, Tertiary Gene Silencing Loss of Heterozygosity DNA Methylation RNA Interference Binding Sites Gene Expression Regulation Gene Deletion Suppression, Genetic Cell Survival Cell Aging G1 Phase Gene Expression Genes, Retinoblastoma Time Factors Oncogenes Phenotype Genes, Neurofibromatosis 2 Ultraviolet Rays Cell Movement Up-Regulation Genes, ras Genes, Wilms Tumor Genes, APC Ubiquitination Cell Differentiation Genes, Reporter Genes, p16 Plasmids Sequence Homology, Amino Acid Alleles Cell Hypoxia S Phase Genetic Vectors Enzyme Activation Dose-Response Relationship, Drug Acetylation Cell Growth Processes Gamma Rays Exons CpG Islands Point Mutation DNA Repair Sequence Deletion Amino Acid Motifs Protein Stability Active Transport, Cell Nucleus Cell Cycle Checkpoints Mutagenesis Protein Transport

Disciplines and Occupations1

Immunohistochemistry

Information Science3

Molecular Sequence Data Base Sequence Amino Acid Sequence

Health Care1

Ultraviolet Rays

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science Health Care

Tumor Suppressor Protein p53 Tumor Suppressor Proteins Genes, Tumor Suppressor Von Hippel-Lindau Tumor Suppressor Protein Tumor Suppressor Protein p14ARF Cell Line, Tumor Retinoblastoma Protein Proto-Oncogene Proteins c-mdm2 Mutation Genes, p53 Molecular Sequence Data Tumor Markers, Biological Gene Expression Regulation, Neoplastic Apoptosis Protein Binding Nuclear Proteins Neurofibromin 2 Transfection Cell Line DNA-Binding Proteins Tumor Burden Adenomatous Polyposis Coli Protein Cell Cycle Transcription Factors Tumor Necrosis Factor-alpha Cell Transformation, Neoplastic Cell Proliferation Cyclin-Dependent Kinase Inhibitor p16 Signal Transduction Proto-Oncogene Proteins Abducens Nerve Base Sequence Neoplasms Promoter Regions, Genetic Ubiquitin-Protein Ligases Neoplasm Proteins Cell Division Cyclin-Dependent Kinase Inhibitor p21 Genes, Suppressor Cell Cycle Proteins Amino Acid Sequence Tumor Cells, Cultured Wilms Tumor RNA, Messenger Phosphorylation DNA Damage Blotting, Western Transcription, Genetic Down-Regulation Cyclins Neoplasms, Experimental Ligases Repressor Proteins E2F Transcription Factors Proteins Kidney Neoplasms Transcriptional Activation Reverse Transcriptase Polymerase Chain Reaction Protein Structure, Tertiary Gene Silencing Loss of Heterozygosity DNA Methylation Cells, Cultured Protein-Serine-Threonine Kinases RNA, Small Interfering Fibroblasts Carrier Proteins DNA, Neoplasm E2F1 Transcription Factor RNA Interference Binding Sites Brain Neoplasms Carcinoid Tumor Recombinant Fusion Proteins HeLa Cells Mice, Nude Immunohistochemistry Gene Expression Regulation Transplantation, Heterologous Adenocarcinoma Suppressor of Cytokine Signaling Proteins Breast Neoplasms WT1 Proteins Gene Deletion Oncogene Proteins, Viral Transcription Factor DP1 Papillomavirus E7 Proteins Cell Nucleus Suppression, Genetic Mice, Inbred C57BL Trans-Activators DNA Primers Neuroendocrine Tumors Antigens, CD2 Osteosarcoma Neoplasm Metastasis Cyclin-Dependent Kinase Inhibitor Proteins Cell Survival Mice, Knockout Models, Biological

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