• Continuous intravenous infusion of ribose (200 milligrams per kilogram per hour) for 24 hours induced a marked stimulation of cardiac adenine nucleotide biosynthesis in unanesthetized and unrestrained rats that had been treated with isoproterenol subcutaneously (25 milligrams per kilogram). (sciencemag.org)
  • The diminution of adenine nucleotides characteristic for the action of high doses of isoproterenol was entirely prevented, and the incidence of the isoproterenol-induced myocardial cell damage was significantly reduced when ribose was administered. (sciencemag.org)
  • E.S. Benson, G.T. Evans, B.E. Hallaway, C. Phibbs, E.F. Freier, Myocardial creatine phosphate and nucleotides in anoxic cardiac arrest and recovery, Amer J Physiol 201: 687-93 (1961). (springer.com)
  • But such patients will pay for the 'scientifically clean' nature of their ischemic insult by being subjected to uncontrolled reperfusion during futile resuscitation attempts, long post-arrest delays attendant to unwitnessed cardiac arrest, and/or medico-legal examination (autopsy or seizure by the medical examiner (ME) or coroner). (alcor.org)
  • To identify biomarkers of interest in nutritional studies, herein we obtained a deep-coverage transcriptome by 454 pyrosequencing of liver and skeletal muscle cDNA normalised libraries from long-term starved gilthead sea bream ( Sparus aurata ) and fish fed different diets. (biomedcentral.com)
  • In the current study, we focused on the mechanism of isoflurane interaction with the sarcK ATP channel and investigated the hypothesis that isoflurane priming involves a long-lasting modulation of channel sensitivity to intracellular nucleotides, adenosine 5′-triphosphate (ATP) and adenosine 5′-diphosphate (ADP), the important regulators of K ATP channels. (asahq.org)
  • Similar to DAG and ceramides, long-chain fatty acyl-CoA (LCFA-CoA) accumulation is associated with insulin resistance in humans, and consumption of a high-fat diet rapidly accumulates LCFA-CoA moieties in association with insulin resistance ( 10 , 11 ). (diabetesjournals.org)
  • Long chain fatty acids bind to carnitine and form long chain acyl carnitine (LCAC), to enter into the mitochondria. (nih.gov)
  • Because APRT activity was 20 fold higher than AdK with similar Km values for substrates, it appeared that adenine (A) is preferred to adenosine for AMP regeneration in the dog's myocardium. (springer.com)
  • Increasingly, public healthcare policy is coming to reflect the reality that neurologists, cardiologists and intensivists have long understood: "CC-CPR doesn't work. (alcor.org)
  • Long-chain acyl-CoA content was varied by varying the nutritional state (fed and starved states) or by addition of oleate. (biochemj.org)
  • These data suggest that the DNA content of groundwater bacteria may be more sensitive than their A(T) to the degree of carbon loading, which may have significant ramifications in the use of nucleic acids and adenine nucleotides for estimating the metabolic status of bacterial communities within more highly contaminated aquifers. (usgs.gov)
  • A useful analogy can be drawn between the ubiquitous cellular nucleotides, ATP and ADP, and the chemicals in an electrical cell or battery. (biologists.org)
  • This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). (wikipedia.org)
  • Its effects after epicutaneous application have long been described in the literature. (uni-halle.de)
  • Our results reveal that (1) This long term model allows serial myocardial sampling in the awake state for investigation of recovery from Isc. (springer.com)
  • Store at -20°C long term. (abcam.com)
  • Because the living genome is duplicated and copied into new generations, one of the merits of using DNA material is long-term data storage within heritable media. (springer.com)
  • The properties of DNA provide the potential for realization of long-term data storage, which can be maintained as archived data for hundreds to thousands of years (Bancroft et al. (springer.com)
  • The latter study involved a 3-km-long transect through a contaminant plume resulting from continued on-land discharge of secondary sewage to a shallow, sandy aquifer on Cape Cod, Mass. With the exception of the most contaminated groundwater immediately downgradient from the contaminant source, DNA and adenylate levels correlated strongly with bacterial abundance and decreased exponentially with increasing distance downgradient. (usgs.gov)