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  • TP53
  • Only one gene, TP53, is mutated in more than 20% of liver cancers while 41 genes each have hypermethylated promoters (repressing gene expression) in more than 20% of liver cancers. (wikipedia.org)
  • fasciola
  • He is best known for his early research (1880-83) into the life cycle of the sheep liver fluke (Fasciola hepatica), a distinction he shared with the German zoologist Rudolf Leuckart, his report on the eruption of Tarawera (1888) and his contribution to the development of New Zealand pedagogy. (wikipedia.org)
  • Under Rolleston's somewhat erratic supervision - his health was failing - Thomas was commissioned by the Royal Agricultural Society to investigate the sheep liver fluke (Fasciola hepatica), a parasite flatworm that in the winter of 1879-80 had caused the loss of some three million sheep in England. (wikipedia.org)
  • These are some of the most common: Fascioliasis, a parasitic infection of liver caused by a Liver fluke of the Fasciola genus, mostly the Fasciola hepatica. (wikipedia.org)
  • Viral
  • Hepatitis, inflammation of the liver, is caused by various viruses (viral hepatitis) also by some liver toxins (e.g. alcoholic hepatitis), autoimmunity (autoimmune hepatitis) or hereditary conditions. (wikipedia.org)
  • Numerous clinical studies have shown that allogeneic blood transfusions are associated with increased mortality and an increased level of serious complications, while potentially exposing the patient to viral, bacterial, or parasitic agents. (wikipedia.org)
  • 1993
  • For example, ambush predators such as Steinernema carpocapsae infect more insects on the surface, while cruising predators like Heterorhabditis bacteriophora infect insects that live deep in the soil (Campbell and Gaugler 1993). (wikipedia.org)
  • bacteria
  • fungi, bacteria and protists that feed on living plants are usually termed plant pathogens (plant diseases), and microbes that feed on dead plants are saprotrophs. (wikipedia.org)
  • Gene
  • For example: in a murine model, Crohn's disease can be precipitated by a norovirus, but only when both a specific gene variant is present and a certain toxin has damaged the gut. (wikipedia.org)
  • inflammatory disease
  • In the Western world, the most common of these is primary sclerosing cholangitis (PSC), an inflammatory disease of the bile ducts which is closely associated with ulcerative colitis (UC). (wikipedia.org)
  • Acute
  • Because people living in affected areas have often been repeatedly exposed, acute reactions are more common in tourists and migrants. (wikipedia.org)
  • therapeutic
  • Moreover, these biomarkers have potential therapeutic effects of paving the way for the development of vaccines for Chagas, which could be extended to other parasitic diseases," Dr. Ndao added. (medindia.net)
  • Neurodegenerative
  • In transthyretin-related hereditary amyloidosis, the liver produces a mutated transthyretin protein which has severe neurodegenerative and/or cardiopathic effects. (wikipedia.org)