• Using a complementary suite of analytical instruments, including liquid chromatography-mass spectrometry (LC-MS), high-performance liquid chromatography (HPLC), gas chromatography mass spectrometry (GC-MS) and nuclear magnetic resonance (NMR), Synex Synthetics offers a fast and accurate analytical service for purity screening, structure identification and structure elucidation. (clinicaltrialsarena.com)
  • High performance LC (HPLC) methods typically use columns packed with 3-μm particles or greater on pumps operating at pressures as high as 6000 psi, while UHPLC methods use 1.7-μm particle columns operating at pressures as high as 15,000 psi. (chromatographyonline.com)
  • Agilent 1260 Binary High-performance liquid chromatograph (HPLC) coupled with Quadrupole Time of Flight Mass Spectrometer (Agilent 6545 QTOF MS). (dri.edu)
  • Shimadzu Prominence HPLC coupled with a triple-quadrupole mass spectrometer (AB Sciex API 3200 LC-MS/MS), equipped with electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI) sources. (dri.edu)
  • Waters high performance liquid chromatograph (HPLC) equipped with Waters 2695 Alliance separation module, Waters 996 Photodiode Array Detector and Empower chromatography software. (dri.edu)
  • High-performance liquid chromatography (HPLC) is a laboratory technique used to separate and identify compounds. (sciencing.com)
  • HPLC differs from standard column chromatography because it uses pressure to force the solution through the column more quickly, and therefore produces quicker, and sometimes more accurate, results. (sciencing.com)
  • Because of the speed of HPLC and it reliance on different polarities of compounds, two compounds with similar structure and polarities can exit the chromatography apparatus at the same time or nearly the same time. (sciencing.com)
  • Although HPLC can often simplify and speed up this process, the cost of developing an HPLC apparatus can become tremendous. (sciencing.com)
  • Developing an HPLC apparatus, although much more efficient, is much more costly than developing other assays for separating compounds. (sciencing.com)
  • In the present study, cordycepin was prepared by preparative high‑performance liquid chromatography (prep-HPLC) and the purity obtained was 99.6%, indicating that this technique may be useful for the large‑scale isolation of cordycepin in the future. (spandidos-publications.com)
  • Preparative high performance liquid chromatography (prep-HPLC) can shorten the production cycle, has relatively low operating costs, and is simple to carry out. (spandidos-publications.com)
  • The present study describes a new method of obtaining high-purity cordycepin by prep-HPLC, which may be useful for the large-scale isolation of cordycepin in the future. (spandidos-publications.com)
  • Jorgenson's research group is also notable for some of the earliest demonstrations of the analysis of the contents of single cells, comprehensive two-dimensional separations, and the invention of ultra-high pressure liquid chromatography. (wikipedia.org)
  • Liquid chromatography is a commonly used means of purification for complex chemical mixtures, a practice generally known as preparative chromatography. (justia.com)
  • In preparative chromatography, a fluid known as the mobile phase is passed under pressure, through a compact bed of particulate material known as the stationary phase. (justia.com)
  • For the effective use of preparative chromatography, it is essential that the bed of stationary phase be prepared as a compact bed of high uniformity. (justia.com)
  • Most preparative chromatography is performed in tubular metal columns of 2, 4 or 6 inch or larger diameter. (justia.com)
  • No. 3,966,609 does produce highly efficient preparative columns which are stabilized against failure due to stationary phase compaction, the method and apparatus described in the patent do not permit the nondestructive removal of packed columns from the compressive means if it is desired to pack a new column. (justia.com)
  • Chemical Analysis of Single Neurons by Open Tubular Liquid Chromatography, R.T. Kennedy, R.L. St Claire III, J.G. White, and J.W. Jorgenson, Microchimica Acta, 1987 (II), 37-45 (1988). (wikipedia.org)
  • Quantitative Analysis of Individual Neurons by Open Tubular Liquid Chromatography with Voltammetric detection, R.T. Kennedy and J.W. Jorgenson, Anal. (wikipedia.org)
  • Longitudinally collapsible apparatus for compacting packing material within a tubular liquid chromatography column. (justia.com)
  • Samples are collected on Teflon filters, extracted with acetonitrile, and analyzed by high pressure liquid chromatography with an ultraviolet detector at 254 nanometers. (cdc.gov)
  • Waters UPLC coupled with electrospray ionization (ESI), atmospheric pressure chemical ionization (APCI) MS/MS, and Evaporative Light Scattering Detector (Waters Acquity UPLC/Quattro micro API/ELSD). (dri.edu)
  • Our students and staff have access to the facilities at the Mark Wainwright Analytical Centre including the DOC Labor Liquid Chromatography - Trace Organic Carbon Detector (LC-OCD). (edu.au)
  • Chemical substance identification in air, bio-environments, medical products, etc., by various methods (apparatus - atomic absorption spectrometer (AAS) - Varian Spektra AAZ220 , phase contrast and light-polarization microscopes, gravimetry, HI8314 membrane pH meters, etc. (rsu.lv)
  • Waters Acquity I-class ultra-high performance liquid chromatography (UPLC) coupled with electrospray ionization (ESI) triple quadrupole tandem mass spectrometer (MS/MS) (Waters Xebo TQ-S MS). (dri.edu)
  • The group currently focuses on ultra-high pressure capillary liquid chromatography combined with mass spectrometry (MS). Jorgenson's research group is best known for their breakthrough in the field of separation sciences, the invention of capillary electrophoresis (CE). (wikipedia.org)
  • A new process set-up based on this phase behavior has been proposed, in which the reaction is carried out in a homogenous phase at high rate (no mass transfer limitations) by selection of a suitable pressure, temperature and CO2 concentration. (tudelft.nl)
  • Typically, ionic liquids possess an extremely low vapor pressure, a high thermal stability, and a wide liquid range. (tudelft.nl)
  • A similar effect was observed in male rats (flow 150 at CDC Public Health Library & Information Center on July 11, 2012 molecule with a vapor pressure of 0.09 torr at 25 C, a log ml/min) with uptake efficiencies of 57, 49, 37, and 36% being observed. (cdc.gov)
  • System control, data collection, and data processing were accomplished using Waters Empower 2 Chromatography Data System software with the Method Validation Manager option. (chromatographyonline.com)
  • 38067407 tender for purchase of cadd software, fluorescent microscope, western blot apparatus, viscometer, fluorescence spectroscope, reactor ready tm lab reactor, automated multipurpose, x ray diffractometer with guidance software, spectrophotometer and ultra high resolution field emission scanning electron microscope with exd for our cicmri laboratory from manufacture/distributors/authorized dealers to participate in the competitive bidding process. (tendersinmaharashtra.com)
  • Two-Dimensional High-Performance Liquid Chromatography/Capillary Electrophoresis", J.W. Jorgenson and M.M. Bushey, U.S. Patent No. 5,131,998. (wikipedia.org)
  • Two-Dimensional High-Performance Liquid Chromatography/Capillary Electrophoresis", J.W. Jorgenson and M.M. Bushey, U.S. Patent No. 5,240,577. (wikipedia.org)
  • The catalytic epoxidation reaction of cinnamyl alcohol in the presence of ionic liquids was optimized with respect to various parameters: (i) type and amount of oxidizing agent, (ii) type and amount of catalyst, (iii) type of ionic liquids (ranging from hydrophobic to hydrophilic), and (iv) temperature. (tudelft.nl)
  • An ultrahigh-pressure liquid chromatography (UHPLC) method was developed to separate paroxetine from several of its related compounds using a systematic screening protocol that monitors combinations of selectivity factors including column chemistry, organic modifier, and pH. (chromatographyonline.com)
  • UHPLC methods take advantage of smaller particle sizes and higher linear velocities, which produce higher efficiency at faster optimum flow rates (7). (chromatographyonline.com)
  • Analytical apparatus, reagents and procedures are described, and calculations are provided for determining sample concentrations. (cdc.gov)
  • With its state-of-the-art analytical equipment, the company's experienced chemists can perform complex separations and isolations using advanced automated flash chromatography systems. (clinicaltrialsarena.com)
  • As shown by MacNair and colleagues (3,4), the use of extremely high pressures in LC can improve the efficiency and reduce analytical time for columns packed with small particles. (chromatographyonline.com)
  • In the physical chemistry courses (CHM 307 and 309), students use lasers, high resolution spectrometers and other modern analytical and diagnostic instruments to probe the energies and dynamic behavior of atoms and molecules. (conncoll.edu)
  • We developed, optimized and validated a fast analytical cycle using high throughput bar adsorptive microextraction and microliquid desorption (HT-BAμE-μLD) for the extraction and desorption of ketamine and norketamine in up to 100 urine samples simultaneously, resulting in an assay time of only 0.45 min/sample. (mdpi.com)
  • Our laboratories are designed in accordance with the standards for the implementation of the physical and chemical parameters: laboratory 1 and 2 (for physicochemical testing), laboratory 3 (for instrumental analyzes) and laboratory 4 (for liquid chromatography). (edu.mk)
  • As a result of these properties, there are many reports where ionic liquids have been used as solvents for chemical reactions. (tudelft.nl)
  • Synex Synthetics delivers high-quality custom synthesis, analysis and rare chemical sourcing. (clinicaltrialsarena.com)
  • First Responders should use a NIOSH-certified Chemical, Biological, Radiological, Nuclear (CBRN) Self Contained Breathing Apparatus (SCBA) with a Level A protective suit when entering an area with an unknown contaminant or when entering an area where the concentration of the contaminant is unknown. (cdc.gov)
  • It differs from Level A in that it incorporates a non-encapsulating, splash-protective, chemical-resistant splash suit that provides Level A protection against liquids but is not airtight. (cdc.gov)
  • The porous architecture allows adsorption of guest molecules with high efficiency, which is advantageous for rapid detection of the guest molecules. (nature.com)
  • The Agilent 8800 provides very high sensitivity and low random background, so detection limits are significantly improved. (hereon.de)
  • Therefore, the high-pressure phase behavior of ternary systems containing epoxidation reaction compounds, ionic liquids and scCO2 were measured. (tudelft.nl)
  • It is a type of column chromatography that relies on different polarities of compounds in a solution in order to separate them. (sciencing.com)
  • Method and Device for High Speed Separation of Complex Molecules", J.W. Jorgenson and C.A. Monnig, U.S. Patent No. 5,269,900. (wikipedia.org)
  • The PEG membrane provides high biological particles separation and prevents sample for clogging due to the strong hydration of functional polymers layer and their resistance to protein adsorption. (llnl.gov)
  • This invention is an improved chromatography device that utilizes the concept of a functionally graded material (FGM) for separation of components. (llnl.gov)
  • The product can be recovered with high purity from one of the two phases that is substantially free of ionic liquid. (tudelft.nl)
  • However, the preparation of high-purity cordycepin remains challenging. (spandidos-publications.com)
  • We've expanded our facilities to include a calibration chamber to conduct cone penetration tests in unsaturated soils as well as a high-performance thermal imaging camera to research progressive development of instability and failure in soil and rock samples. (edu.au)
  • Phase behavior experiments were carried out using a synthetic method in the Cailletet apparatus at five different concentrations of CO2, at temperatures and pressures up to 368 K and 12.1 MPa, respectively. (tudelft.nl)
  • 0.4 When added to oils of high quality and stored at temperatures below 25oC, vitamin A is relatively stable to changes during storage. (who.int)
  • LLNL's high throughput method involves proteome-wide screening for linear B-cell epitopes using native proteomes isolated from a pathogen of interest and convalescent sera from immunized animals. (llnl.gov)
  • First, the epoxidation reaction of cinnamyl alcohol to 3-phenylglycidol was studied in the presence of ionic liquids as solvents. (tudelft.nl)
  • In order to scale up the reaction in an ionic liquid/scCO2 miscibility switch system, a study was started to select the optimum ionic liquid in this case. (tudelft.nl)
  • Different models of the device incorporate various instrumentation such as micro analysis apparatus, double beam, single, or dual channel photometers, and bichromatic 2-wavelength photometers. (fda.gov)
  • Due to its high temperature of about 7000 K almost all molecules are atomised, excited and ionised. (hereon.de)
  • The maintenance of a Quality Management System was related to the implementation of the MKC EN ISO/IEC 17025 standard. (edu.mk)
  • However, by increasing the concentration of CO2 (more than 40 mol%) higher pressures are necessary to completely dissolve CO2 in the system containing cinnamyl alcohol compared to (2S,3S)-(-)-3-phenylglycidol. (tudelft.nl)
  • The described invention is a miniature fluidic device for separating particles suspended within a liquid sample that is introduced into the interior volume of the device. (llnl.gov)
  • Moreover, it is shown before that CO2 is able to force two immiscible liquid phases to form one homogeneous phase as CO2 pressure increases. (tudelft.nl)
  • Preparation of such large diameter columns is difficult using conventional slurry packing wherein a suspension of stationary phase is forced or "packed" into a chromatographic column using a high pressure stream of liquid to produce a homogeneous and stable column structure. (justia.com)
  • Outline an expression and purification strategy, using both traditional and high-throughput methods, to produce a sample suitable for protein crystallography. (hideyuki-ts.com)
  • In high-throughput approaches, such as the pipeline adopted by Oxford Protein Production Facility (OPPF), many variants are constructed in parallel to maximise output. (hideyuki-ts.com)
  • 3) As commonly designed, fixed oil tanks often are interconnected for both liquid and vapor, allowing contents to equalize over multiple tanks. (cdc.gov)
  • 8805;99% for the most penetrable particle sizes) and a reasonable pressure drop (up to 16.7 kPa) to accommodate high dust loading. (cdc.gov)
  • Baicalein had higher concentration and yield than other flavonoids in 2008. (auburn.edu)
  • Baicalin was higher in concentration and yield than other flavonoids in 2009.Flavonoid yield was 58% higher in the first harvest than in the second harvest in year 2 (2009). (auburn.edu)
  • Thus, the concentration dependence of volatility and high lipophilicity of naphthalene. (cdc.gov)
  • This study shows for the first-time application of microcapillary antibiotic susceptibility testing (mcAST) directly from clinical samples, using minimal equipment and simple liquid handling, and with kinetics of growth recorded using a smartphone camera. (bvsalud.org)
  • Indoor Air: Mercury can be released into indoor air as a liquid spray (aerosol) or as a vapor. (cdc.gov)
  • Agricultural: If mercury is released into the air as a liquid spray (aerosol), it has the potential to contaminate agricultural products. (cdc.gov)
  • This interesting behavior, which is known as the miscibility switch phenomenon, is generally applicable for ternary systems containing ionic liquids, CO2 and organics. (tudelft.nl)
  • Both ternary systems (cinnamyl alcohol + ionic liquid + CO2 and (2S,3S)-(-)-3-phenylglycidol + ionic liquid + CO2) only show one type of phase transition (liquid-vapor to liquid) at the highest pressures studied. (tudelft.nl)