• article{b2288a16-99b9-4595-8bca-410a9662bee1, abstract = {The 3-hydroxy fatty acids (3-OHFAs) in lipopolysaccharides (LPS) play an important role in determining endotoxin activity, and childhood exposure to endotoxin has recently been associated with reduced risk of atopic diseases. (lu.se)
  • Four chemotypes of the rough lipopolysaccharides (LPS) membrane from Pseudomonas aeruginosa were investigated by a combined approach of explicit water molecular dynamics (MD) simulations and Poisson-Boltzmann continuum electrostatics with the goal to deliver the distribution of the electrostatic potential across the membrane. (diva-portal.org)
  • We proposed MSC-derived MVs as potent regulators of microglia activation and used an in vitro model of stimulation for BV-2 cells, a microglia cell line, with lipopolysaccharides (LPS). (fraunhofer.de)
  • The microglial activation plays an important role in neurodegenerative diseases by producing several proinflammatory cytokines and nitric oxide (NO). We found that three types of isoflavones and their metabolites that are transformed by the human intestinal microflora suppress lipopolysaccharide (LPS)-induced release of NO and tumor necrosis factor (TNF)-α in primary cultured microglia and BV2 microglial cell lines. (aspetjournals.org)
  • H. pylori lipopolysaccharide (LPS) has been recognized as a primary virulence factor evoking acute mucosal inflammatory reaction. (nih.gov)
  • My undergraduate research advisor Dr. Gee Lau's laboratory has previously shown that multiple PA virulence factors, including pyocyanin, lipopolysaccharides (LPS), flagellum, and alginate are capable of causing mucus hypersecretion in airways. (illinois.edu)
  • Dexamethasone (1 mg/kg, i.p.) administered either 1 hr before or 1 hr after E. coli lipopolysaccharide (LPS, 4 mg/kg, i.p.) in conscious rats inhibited the subsequent (4 hrs) rise in plasma cytokine (interleukin [IL]-1β, tumour necrosis factor [TNF]-α), nitrate/nitrite (NO × ), soluble intercellular adhesion molecule-1 (sICAM-1) concentration and lung/liver myeloperoxidase activity indicative of an anti-inflammatory effect. (wiley.com)
  • Lipopolysaccharides-mediated increase in glucose-stimulated insulin secretion: Involvement of the glucagon-like peptide 1 (GLP1) pathway. (diabetesjournals.org)
  • Helicobacter pylori lipopolysaccharide hinders polymorphonuclear leucocyte apoptosis. (nih.gov)
  • Compositional analysis of Helicobacter pylori rough-form lipopolysaccharides. (asm.org)
  • Sodium dodecyl sulfate-polyacrylamide gel electrophoresis was used to analyze the macromolecular heterogeneity of lipopolysaccharides (LPS) from seven fresh clinical isolates and three culture collection strains of the human pathogen Helicobacter pylori. (asm.org)
  • A lipopolysaccharide (LPS) has been isolated by phenol-water extraction from the cells of the blue-green alga Mastigocladus laminosus . (springer.com)
  • The aim of this study was to assess both glycerol permeability and metabolism in undifferentiated 3T3-L1 cells (UDCs) as well as in untreated (CTL-DCs) versus lipopolysaccharide (LPS-DCs)-treated differentiated 3T3-L1 adipocytes. (mdpi.com)
  • The injection of lipopolysaccharides significantly increased the average size of bone marrow fat cells as compared to the negative controls, and such increase was significantly and markedly reduced with D-003. (ijpsonline.com)
  • It is concluded that D-003 reduced the incidence, number and percent areas of osteonecrosis lesions, and the size of bone marrow fat cells, a marker of adipogenesis, in rabbits with lipopolysaccharides-induced ostenonecrosis. (ijpsonline.com)
  • The outer membrane and its LPS [lipopolysaccharides] helps gram-negative cells excel in the intestines and other host environments. (harvard.edu)
  • De Castro C, Parrilli M, Holst O, Molinaro A (2010) Microbe-associated molecular patterns in innate immunity: extraction and chemical analysis of gram-negative bacterial lipopolysaccharides. (springer.com)
  • Characterization of lipopolysaccharides present in settled house dust. (cdc.gov)
  • We have extended this concept to birds by demonstrating that lipopolysaccharide (LPS) injected intraperitoneally (i.p.) increases body temperature (T$\sb{\rm b}$), reduces feed intake, increases somnolence, decreases plasma (Fe) and (Zn), increases plasma (Cu), and elevates plasma corticosterone. (illinois.edu)
  • A previous study indicated that lipopolysaccharides (LPS) extracted from Actinobacillus pleuropneumoniae bind two low-molecular-mass proteins, of approximately 10 and 11 kDa, present in porcine respiratory tract secretions (M. Bélanger, D. Dubreuil, and M. Jacques, Infect. (asm.org)
  • Also, a model of non-steroid and non-traumatic ON by use of a single- and low-dose lipopolysaccharide (LPS) injection in rabbits is useful to assess the pathogenesis of non-steroid ON in humans, and to investigate the potential value of preventive and therapeutic strategies [ 7 ]. (ijpsonline.com)