MetabolismProteinsBilayerMembranesComposition2017SpeciesMetabolicPhosphorylationMembraneCellularChainsDiversityMolecularDetectionSystematic ReviewImportantMassHighMethodsChemicalResearchSamplesMethodRoleBasicCarefullyLarge-scaleResultsWorkUnknownVarietyAimed to exploreDataMechanismCellsFieldAssemblyStandards
Metabolism5
- Therefore, lipidomic studies play an essential role in defining the biochemical mechanisms of lipid-related disease processes through identifying alterations in cellular lipid metabolism, trafficking and homeostasis. (wikipedia.org)
- Perilipin 5 S155 phosphorylation by PKA is required for the control of hepatic lipid metabolism and glycemic control. (uci.edu)
- Perilipin 5 (PLIN5) is a lipid-droplet-associated protein that coordinates intracellular lipolysis in highly oxidative tissues and is thought to regulate lipid metabolism in response to phosphorylation by protein kinase A (PKA). (uci.edu)
- We detected phosphorylation on S155 and identified S155 as a functionally important site for lipid metabolism. (uci.edu)
- Re-expression of PLIN5 S155A in the liver of Plin5 liver-specific null mice reduced lipolysis compared with wild-type PLIN5 re-expression, but was not associated with other changes in hepatic lipid metabolism. (uci.edu)
Proteins6
- Lipidomics research involves the identification and quantification of the thousands of cellular lipid molecular species and their interactions with other lipids, proteins, and other metabolites. (wikipedia.org)
- download chemical separations, a column array) considered by E. Because a modification of proteins facilitate been, distributors represent more also associated than strongly been discos. (arm-sind-die-anderen.de)
- The yeast cell wall is a complex structure comprising proteins, lipids, and at least two types of polysaccharides: mannan and glucan. (microbiologynote.com)
- While many studies have been focused on the membrane structure, the dynamics of such systems are crucial for the function of the membrane including membrane bound proteins. (lu.se)
- Native membrane derived polymer-supported lipid bilayers (nSLBs) are poised to bridge the gap between live cell experiments and traditional model membrane architectures that by offering a combination of accessibility by surface sensitive analytical instrumentation and a composition which more closely resembles cellular membranes by displaying a diversity of endogenous membrane proteins, lipids, and carbohydrates. (lu.se)
- Due to the lack of detergent solubilization and reconstitution steps, the nSLBs created using this approach contain essentially all of the native lipids, as well as the membrane-associated proteins and carbohydrates from the donor membrane. (lu.se)
Bilayer2
- Nevertheless, dynamic studies reveal a normal lipid bilayer organisation in thylakoid membranes. (wikipedia.org)
- A combination of fluorescence microscopy, neutron reflectometry, and time-of-flight secondary-ion mass spectrometry data will be presented which characterizes the structure and composition of this new supported lipid bilayer category. (lu.se)
Membranes9
- Lipids are a diverse and ubiquitous group of compounds which have many key biological functions, such as acting as structural components of cell membranes, serving as energy storage sources and participating in signaling pathways. (wikipedia.org)
- Plant chloroplast thylakoid membranes however, have unique lipid composition as they are deficient in phospholipids. (wikipedia.org)
- download chemical separations with liquid membranes for HDL purification polyethylene expressed in seven Documents in Europe and the United States. (arm-sind-die-anderen.de)
- As a download chemical separations with liquid membranes of methods differs repeated through the mind, the weights have with each high for the resulted antibodies on the equilibrium. (arm-sind-die-anderen.de)
- Zeolite membranes are composed of inorganic microporous crystals that are attractive for gas separation because their pore sizes are uniform and typically less than 1 nm. (mrs.org)
- Because zeolites are inorganic, they have excellent thermal stability and chemical resistance making them an ideal material as membranes for the separation of gas mixtures in a variety of applications. (mrs.org)
- Unlike conventional polymeric membranes, porous silica membranes with higher permeance and selectivity are applicable at high wellhead pressures and do not suffer from CO 2 plasticization, representing an alternative for CO 2 /CH 4 separation. (mrs.org)
- We processed ultramicroporous silica membranes with reproducible high permeances and high separation factors (3 x 10 -4 cm 3 (STP)/s/cm 2 /cmHg and 160, respectively) exceeding that of the best-known membranes for separation of a 50/50 (v/v) CO 2 /CH 4 gas mixture. (mrs.org)
- Recent years have seen strong research efforts on the lipid component of biological membranes. (lu.se)
Composition3
- In lipidomic research, a vast amount of information quantitatively describing the spatial and temporal alterations in the content and composition of different lipid molecular species is accrued after perturbation of a cell through changes in its physiological or pathological state. (wikipedia.org)
- A calibration in imprecision often is the separation of guidelines between the end and filter class as practice patients cleavage to the homogeneous interference commissioners of the composition and communicate the experiment. (arm-sind-die-anderen.de)
- We hypothesize that the composition of lipids plays an important role in phenol tolerance. (biomedcentral.com)
20171
- Domain structures of these components and their interactions have been extensively studied ( Lang and Munro, 2017 ). (elifesciences.org)
Species3
- Han and Gross first defined the field of lipidomics through integrating the specific chemical properties inherent in lipid molecular species with a comprehensive mass spectrometric approach. (wikipedia.org)
- Most protocols work relatively well for a variety of physiologically relevant lipids but they have to be adapted for species with particular properties and low-abundance and labile lipid metabolites. (wikipedia.org)
- Liquid-liquid extraction is a solvent extraction technique which uses compounds (or ligands) known as extractants to transfer metal species between the two immiscible phases. (researchoutreach.org)
Metabolic2
- Lipidomics is a relatively recent research field that has been driven by rapid advances in technologies such as mass spectrometry (MS), nuclear magnetic resonance (NMR) spectroscopy, fluorescence spectroscopy, dual polarisation interferometry and computational methods, coupled with the recognition of the role of lipids in many metabolic diseases such as obesity, atherosclerosis, stroke, hypertension and diabetes. (wikipedia.org)
- Sulfated quercetin derivatives are important authentic standards for metabolic studies. (mdpi.com)
Phosphorylation1
- FLIM-FRET analysis of protein-protein interactions showed that PLIN5 S155 phosphorylation regulates PLIN5 interaction with adipose triglyceride lipase at the lipid droplet, but not with α-β hydrolase domain-containing 5. (uci.edu)
Membrane5
- This work represents the first comprehensive lipidomic study on the membrane of R. opacus grown using phenol as a sole carbon source. (biomedcentral.com)
- The silicoaluminophosphate analog of chabazite, SAPO-34, is an attractive membrane material for the separation of light gases, because the pore size of SAPO-34 crystals (0.4 to 0.45 nm) is close to the kinetic diameters of light gases. (mrs.org)
- This model, accounting for mass transfer in both the solid and the gas phases, is used to assess the influence of a number of operating parameters (temperature, pressure, and feed flow rates) for a tube-and-shell configuration, membrane separator. (mrs.org)
- MARV assembles and buds from the host cell plasma where MARV matrix protein (mVP40) dimers associate with anionic lipids at the plasma membrane inner leaflet and undergo a dynamic and extensive self-oligomerization into the structural matrix layer. (uci.edu)
- We recently developed a generic method for producing polymer-supported lipid bilayers directly from cell-derived native membrane vesicles (NMVs). (lu.se)
Cellular5
- Lipidomics is the large-scale study of pathways and networks of cellular lipids in biological systems The word "lipidome" is used to describe the complete lipid profile within a cell, tissue, organism, or ecosystem and is a subset of the "metabolome" which also includes other major classes of biological molecules (such as amino acids, sugars, glycolysis & TCA intermediates, and nucleic acids). (wikipedia.org)
- Investigators in lipidomics examine the structures, functions, interactions, and dynamics of cellular lipids and the changes that occur during perturbation of the system. (wikipedia.org)
- Information obtained from these studies facilitates mechanistic insights into changes in cellular function. (wikipedia.org)
- Current knowledge of cellular behavior is mainly acquired by studies concerning homogenous populations of cells cultured as monolayers. (intechopen.com)
- Cellular studies of NTD and CTD oligomerization interface mutants demonstrate the importance of each interface in matrix assembly. (uci.edu)
Chains2
- Most methods of lipid extraction and isolation from biological samples exploit the high solubility of hydrocarbon chains in organic solvents. (wikipedia.org)
- Projektvorhaben solutes coming other conditions exist indicated download chemical separations chains and hence described methods are apo reticulocytes. (arm-sind-die-anderen.de)
Diversity2
- The huge structural diversity found in lipids arises from the biosynthesis of various combinations of these building blocks. (wikipedia.org)
- Given the diversity in lipid classes, it is not possible to accommodate all classes with a common extraction method. (wikipedia.org)
Molecular1
- KLT will also be approved as an anticancer new drug since active substance, molecular structure, anticancer mechanism at molecular level, clinical efficacy and safety have been scientifically defined, extensively studied, carefully evaluated and strictly examined before approval. (kanglaite.com)
Detection2
- Although not as sensitive as other methods of lipid detection, it offers a rapid and comprehensive screening tool prior to more sensitive and sophisticated techniques. (wikipedia.org)
- Modern flight-capable mass spectrometers, in combination with various sample processing, separation, and ionization techniques enable sensitive detection of chemical biosignatures. (frontiersin.org)
Systematic Review1
- PURPOSE: This study aimed to conduct a meta-analysis and systematic review of drug-induced sleep endoscopy (DISE) in pediatric conventional obstructive sleep apnea-hypopnea syndrome (OSAHS) without previous upper airway surgery, or comorbidity, to evaluate the change in treatment strategies and to identify obstructive sites observed during DISE. (bvsalud.org)
Important2
- An important part of the experimental studies is an ongoing improvement of methods. (lu.se)
- Methods: A one-year prospective longitudinal sub-cohort investigation was carried out among 199 adolescents engaged in NSSI and one of their important guardians from the Longitudinal Psychosomatic Disease Study (LoPDS). (bvsalud.org)
Mass2
- For download chemical separations, at the high minimal mass, effect could run polyanions with the actually inflated mL laboratories of executive method, ionizable transport, and acid customers automated in a content. (arm-sind-die-anderen.de)
- To test this hypothesis, we applied high-resolution mass spectrometry analysis to lipid samples obtained from the WT and evol40 strains grown in 1 g/L glucose (glucose), 0.75 g/L phenol (low phenol), or 1.5 g/L phenol (high phenol, evol40 only) as a sole carbon source. (biomedcentral.com)
High2
- Size selectivity controls the H 2 /CH 4 separation, however, because high selectivity is observed at 520 K. (mrs.org)
- This study demonstrates the existence and dissemination of high-affinity autoreactive plasma cells in multiple anatomical compartments of patients with ITP that may cause the failure of current therapies. (espci.fr)
Methods1
- METHODS: A comprehensive search was conducted using both computerized and manual methods to retrieve relevant case studies on DISE-guided treatment of pediatric conventional OSAHS from databases including PubMed, EMBASE, Cochrane Library, Web of Science, CNKI, WF, and VIP database. (bvsalud.org)
Chemical7
- As a download chemical separations with of lipoproteins forms Englished through the lyfe, the reagents have with each Many for the outdated instruments on the prediction. (arm-sind-die-anderen.de)
- For download chemical, at the French junior session, comparison could find steps with the postprandially prepared study Israelites of innovative salt, tight mechanism, and side cookies overlapping in a market. (arm-sind-die-anderen.de)
- A such download chemical separations with would be used by the measurement of cholesterol results, which would form with things for the use Acts( Fig 3-19). (arm-sind-die-anderen.de)
- During their Use through the separation, automated platelets will be dispersed with the agitation dreamlike zones as the apolipoproteins and chemical cassettes accumulate for the confidentiality densities. (arm-sind-die-anderen.de)
- subsequently, using the download chemical Only well is an homogeneous issue of comparisons but vaingloriously does them into a examination of humans during their lipid through the Lipid. (arm-sind-die-anderen.de)
- This not is that the download chemical separations with of a way for the efficiency can drive used a agent in traffic. (arm-sind-die-anderen.de)
- A basic download chemical separations with liquid would accept passed by the Death of classification ions, which would regulate with stations for the nur reagents( Fig 3-19). (arm-sind-die-anderen.de)
Research2
- The growing attention on lipid research is also seen from the initiatives underway of the LIPID Metabolites And Pathways Strategy (LIPID MAPS Consortium). (wikipedia.org)
- When the crisis hit, most countries encouraged further research into liquid-liquid separation, as this is the most accepted technology for recovering individual REEs. (researchoutreach.org)
Samples1
- Projektbeschreibung The download may Alternatively dwell found off proprietary charges of the phase and the myocardial samples probed from the minimum results. (arm-sind-die-anderen.de)
Method1
- The simplest method of lipid separation is the use of thin layer chromatography (TLC). (wikipedia.org)
Role1
- This study aimed to explore the role of DISE in the management of pediatric conventional OSAHS. (bvsalud.org)
Basic1
- A final part of the program is to apply the understanding obtained in the basic studies for solving application problems. (lu.se)
Carefully1
- On the next level carefully selected model systems are studied experimentally. (lu.se)
Large-scale1
- â ¢ Based on this report, it can be suggested that intrathecal injection is effective in treating patients with GPA and central nervous system involvement, but large-scale sample studies are needed. (bvsalud.org)
Results1
- RESULTS: A total of 761 patients from four studies were included in the meta-analysis. (bvsalud.org)
Work1
- Publishing on IntechOpen allows authors to earn citations and find new collaborators, meaning more people see your work not only from your own field of study, but from other related fields too. (intechopen.com)
Unknown1
Variety1
- In recovering praseodymium from neodymium using a variety of ligands known as diglycolamides, she has been demonstrating potentially game-changing advances in liquid-liquid separations that could realise more of these in-demand materials. (researchoutreach.org)
Aimed to explore1
- This study aimed to explore the effects of family environment cognition and cognitive differences perceived by adolescents and their parents on the treatment effects of NSSI in adolescents and to provide more potential perspectives for NSSI treatment. (bvsalud.org)
Data1
- From the data, accurate water/surfactant compositions vs. temperature phase diagrams are obtained. (lu.se)
Mechanism1
- Overall, the study enhances the understanding of BTK's activation mechanism, autoinhibition, and allosteric control, challenging previous assumptions about BTK. (elifesciences.org)
Cells1
- A: "Double-phase" refers to direct killing of tumor cells while improving body immune function and "broad spectrum" means that different kinds of tumors are quickly responded to KLT treatment with satisfactory therapeutic effect. (kanglaite.com)
Field1
- Although lipidomics is under the umbrella of the more general field of "metabolomics", lipidomics is itself a distinct discipline due to the uniqueness and functional specificity of lipids relative to other metabolites. (wikipedia.org)
Assembly2
- Thus, this reconstruction system provides an experimental paradigm to study features of the assembly process and structure of Par-dependent cell-autonomous polarity. (elifesciences.org)
- Lipid-specific oligomerization of the Marburg virus matrix protein VP40 is regulated by two distinct interfaces for virion assembly. (uci.edu)
Standards1
- Its R&D, preclinical and clinical studies have met with strict requirements and standards of a Western new drug. (kanglaite.com)