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  • concentration
  • A5 and lines selected from it have a DNA fragment missing compared to A23 and lines with normal linolenic acid concentration. (springer.com)
  • Seventy F 4:5 lines from a population segregating for linolenic acid concentration were scored for presence or absence of the fragment. (springer.com)
  • These results suggest that the reduced linolenic acid concentration in A5 was at least partially the result of a full or partial deletion of a microsomal ω-3 desaturase gene. (springer.com)
  • fatty acid metab
  • Omega-3 fatty acids can modulate the expression of a number of genes, including those involved with fatty acid metabolism and inflammation. (hmdb.ca)
  • Fatty Acid Metabolism in Carriers of Apolipoprotein E Epsilon 4 Allele: Is It Contributing to Higher Risk of Cognitive Decline and Coronary Heart Disease? (mdpi.com)
  • diets
  • Western modern diets are deficient in omega-3 polyunsaturated fatty acids, which are essential for brain health. (archives-ouvertes.fr)
  • The results of the present study show that flaxseed oil as a source of α-linolenic acid can be incorporated into the diets of goats to enrich goat meat with n -3 fatty acids, upregulate the PPARα and PPARγ, and downregulate the SCD gene expression. (mdpi.com)
  • flax
  • Industrial oil flax ( Linum usitatissimum ) and edible oil or solin flax differ markedly in seed linolenic acid levels. (plantphysiol.org)
  • Despite the economic importance of low-linolenic-acid or solin flax, the molecular mechanism underlying this trait has not been established. (plantphysiol.org)
  • Two independently inherited genes control the low-linolenic-acid trait in flax. (plantphysiol.org)
  • Furthermore, the low-linolenic-acid phenotype in flax was complemented by transformation with a wild-type gene. (plantphysiol.org)
  • Codominant DNA markers were developed to distinguish between null and wild-type alleles of both genes, and linolenic acid levels cosegregated with genotypes, providing further proof that LuFAD3A and LuFAD3B are the major genes controlling linolenic acid levels in flax. (plantphysiol.org)
  • The seed oil of flax ( Linum usitatissimum ) is notable for its high level of linolenic acid, generally around 45% to 65%, which gives it a high drying quality, making it useful for industrial purposes. (plantphysiol.org)
  • Compared to oil from traditional flax cultivars, low-linolenic-acid oil is less subject to rapid oxidation and is thus more competitive as a cooking or salad oil ( Bhatty, 1995 ). (plantphysiol.org)
  • Two recessive genes at independent loci control the low-linolenic-acid trait in flax ( Rowland, 1991 ). (plantphysiol.org)
  • Here, we present the sequences of two microsomal FAD3 desaturase cDNAs from flax and demonstrate that these two genes control the low-linolenic-acid trait in flaxseed. (plantphysiol.org)
  • genes
  • A dramatic reduction in transcript levels of both genes occurred in the low-linolenic-acid solin line, which was likely due to nonsense-mediated decay. (plantphysiol.org)
  • The aim of this study was to determine the effect of flaxseed oil or sunflower oil in the goat diet on fatty acid composition of muscle and expression of lipogenic genes in the semitendinosus (ST) muscle. (mdpi.com)
  • phospholipids
  • It is also possible that γ- linolenic acid administration results in the movement of arachidonate from phospholipids, which normally provide arachidonate for prostablandin production. (annals.org)
  • atherosclerosis
  • Flaxseed Oil Containing α -Linolenic Acid Ester of Plant Sterol Improved Atherosclerosis in ApoE Deficient Mice," Oxidative Medicine and Cellular Longevity , vol. 2015, Article ID 958217, 17 pages, 2015. (hindawi.com)
  • diet
  • 1,8 However, these foods generally do not contribute much α-linolenic acid to the diet. (ahajournals.org)
  • Cholesterol-lowering Medications -- Increasing the amount of omega-3 fatty acids in your diet may help a group of cholesterol-lowering medications known as statins work more effectively. (limamemorial.org)
  • high
  • Not enough is known yet to be able to rate alpha-linolenic acid's effect on high cholesterol. (webmd.com)
  • 0.05) upregulation of PPARα and PPARγ gene expression and downregulation of stearoyl-CoA desaturase (SCD) gene in the ST muscle for the high α-linolenic acid group compared with the low α-linolenic acid group. (mdpi.com)
  • proteins
  • Although humans and other mammals can synthesize saturated and some monounsaturated fatty acids from carbon groups in carbohydrates and proteins, they lack the enzymes necessary to insert a cis double bond at the n-6 or the n-3 position of a fatty acid. (hmdb.ca)
  • Exposure
  • The effect of fatty acids on paclitaxel chemosensitivity was determined by comparing IC(50) and IC(70) (50 and 70% inhibitory concentrations, respectively) obtained when the cells were exposed to IC(50) and IC(70) levels of paclitaxel alone and fatty acids were supplemented either before or during the exposure to paclitaxel. (chiro.org)