• One unexpected result from the study sheds light on how DNA damage is repaired in a cell. (news-medical.net)
  • This finding sheds light on the differential market reactions to macroeconomic problems in seemingly comparable countries. (lu.se)
  • This sheds light upon the role of the Smad7 protein in this system. (lu.se)
  • The study, published in Molecular Psychiatry , is the largest of its kind and may shed light on the biological mechanism by which environmental influences regulate the activity of certain genes and in turn contribute to the development of ASD and related behaviour traits. (kcl.ac.uk)
  • Nuclear-electronic (vibronic) coupling is increasingly recognized as a mechanism of major importance in controlling the light-induced function of molecular systems. (nature.com)
  • In summary, the researchers conclude that through this study, they were able to elucidate the molecular mechanisms involved in gastric carcinogenesis induced by H. pylori, gain insights into the role of the Wnt/PCP pathway in carcinogenesis, and propose it as a potential target for clinical interventions against H. pylori cagA + infections. (medicalxpress.com)
  • Researchers have identified a key process in cell death that prevents cancer from spreading through a distinct molecular mechanism of the disease's early stages. (webindia123.com)
  • The finding builds on previous studies by the team on the molecular mechanism of membrane-bound Bcl-2 to inform a more complete understanding of the early stages of apoptosis. (webindia123.com)
  • However, the molecular mechanisms that lead to such damages are unknown. (ucla.edu)
  • Because singlet oxygen does not travel very far within a cell, the molecular effects are influenced by the intracellular localization of the photosensitizer at the time of light exposure. (medscape.com)
  • Further work is now needed to investigate the exact molecular mechanisms behind the activation of p63. (elifesciences.org)
  • However, the underlying molecular mechanisms remained unclear. (europa.eu)
  • We believe that this mechanism for disarming macrophages develops early in cancer cells, enabling small tumors to survive and grow," adds Guttridge, who also is in the OSUCCC - James Molecular Carcinogenesis and Chemoprevention Program. (medicalxpress.com)
  • Fundamental studies of photoelectrochemical processes in complex materials, including photophysics and photochemistry of light-harvesting and light-emitting molecules, as well as energy and electron transfer processes in supramolecular systems and molecular-semiconductor hybrid nanomaterials. (lu.se)
  • Molecular and materials predictions of emerging solar energy technologies including Dye-Sensitized Solar Cells (DSSCs), Organic Photovoltaics (OPVs), nanoscale energy converters, Light-emitting materials, as well as Solar Fuels including Artificial Photosynthesis. (lu.se)
  • Understanding the mechanisms involved in these inherited disorders may shed light on biological mechanisms and natural history of COVID-19. (cdc.gov)
  • Despite 50 years of research, the pathophysiological mechanisms that lead some patients to develop a severe clinical form of dengue have not yet been clearly elucidated. (pasteur.fr)
  • Scientists from the Institut Pasteur in Paris and the Institut Pasteur in Cambodia, in collaboration with teams from the CNRS and Inria, have demonstrated that asymptomatic dengue infection in children is associated with activation of the immune system via control mechanisms, resulting in the elimination of viral infection without excessive immune activation. (pasteur.fr)
  • With this Perspective, we aim to summarize what is known about biosensor structure and mechanisms and, based on this foundation, provide guidelines to accelerate the development of a broader range of biosensors with performance comparable to that of the GCaMP series. (nature.com)
  • In this paper, we will review the new progress in the methods for preparing stable nanofluids and summarize the stability mechanisms. (hindawi.com)
  • This analysis discriminates between different biological mechanisms to achieve a transient signal from a sustained TGF-b input, where one mechanism is to use a negative feedback to turn the signal off. (lu.se)
  • The markers are excited to a higher energy state, from which they emit light of a longer wavelength (via fluorescence decay) when they return to the ground state. (mpg.de)
  • Fig. 6: GFP- and RFP-based biosensor structures provide insight into the mechanism of the fluorescence response. (nature.com)
  • Following blue or red light activation, porphyrins are excited to a higher energy triplet state, which can either emit light (fluorescence) or generate reactive oxygen species, such as singlet oxygen or free radicals. (medscape.com)
  • Depolarized dynamic light scattering, broadband dielectric spectroscopy, rheology, and differential scanning calorimetry were employed to systematically study the influence of MW on the mechanism of ionic transport and segmental dynamics in these materials. (osti.gov)
  • I found that progressive denervation may alter DA signaling by three independent mechanisms depending on degree of denervation and macroscopic morphology of the lesion. (jneurosci.org)
  • We conclude that non-photochemical quenching is catalysed by two independent mechanisms, with the fastest activated response catalysed within monomeric LHC proteins depending on both zeaxanthin and lutein and on the formation of a radical cation. (lu.se)
  • Scientists at Nagoya Institute of Technology (NITech) and collaborating universities in Japan have gained new insights into the mechanisms behind degradation of a semiconductor material that is used in electronic devices. (electroiq.com)
  • A new study published in Science Signaling on 18 July 2023 shares insights into the additional mechanism of oncogenic CagA action. (medicalxpress.com)
  • We are confident that these insights will contribute to a detailed understanding of light-induced phase segregation and ion migration in general. (lu.se)
  • 1] Despite tremendous efforts, the reliable and stable operation of metal halide perovskites is still hindered by dynamic phenomena such as current-voltage hysteresis,[3, 4] dynamic defect formation,[5, 6] degradation and light-induced phase segregation. (lu.se)
  • Light at a wavelength corresponding to a peak of the porphyrin excitation spectrum in tissues is used to most efficiently generate a therapeutic effect. (medscape.com)
  • Because P acnes has been shown to naturally accumulate porphyrins, blue or red light alone can also have a direct therapeutic photodynamic effect on the bacteria. (medscape.com)
  • The researchers studied an epigenetic mechanism called DNA methylation. (kcl.ac.uk)
  • In order to better understand the actual mechanism behind atomic deformation that lead to degradations, the researchers used photoluminescence to induce movement of electric charge particles and measured the speeds at which that took place. (electroiq.com)
  • A group of researchers has discovered a new mechanism of DNA repair, which opens up new perspectives for the treatment and prevention of neurodegenerative diseases. (sciencedaily.com)
  • A group of researchers, lead by Vasily M. Studitsky, professor at the Lomonosov Moscow State University, discovered a new mechanism of DNA repair, which opens up new perspectives for the treatment and prevention of neurodegenerative diseases. (sciencedaily.com)
  • A group of researchers, lead by Vasily M. Studitsky, studied the mechanism of detection of single-stranded DNA breaks at which the connection is lost between nucleotides on one strand in the places where the DNA is associated with histones. (sciencedaily.com)
  • STED microscopy radically distinguishes itself from conventional far-field light microscopy in the fact that its resolution is no longer fundamentally limited by the wavelength of light used. (mpg.de)
  • The second step involves the activation of the photosensitizer in the presence of oxygen with a specific wavelength of light directed toward the target tissue. (medscape.com)
  • Ophthalmic research into the appearance of blue light lesions has not ruled out the possibility that short wavelength light (visible light with wavelengths of less than 500 nm) may contribute to premature aging of the retina and to senile macular degeneration [6]. (who.int)
  • In a recent issue of Development, former Desplan student Mathias Wernet deciphered the transcriptional network that specifies the region of the Drosophila eye responsible for the detection of the vector of light polarization that allows insects to navigate when the sun is not present. (nyu.edu)
  • More specifically, these lights have a potential application for use in transillumination with white light for the detection of caries and calculus and the examination of existing restorations [12]. (who.int)
  • The research, 'Cryptochrome-Timeless Structure Reveals Circadian Clock Timing Mechanisms' published April 26 in Nature . (news-medical.net)
  • The Treaty Establishing the European Stability Mechanism was signed by the member states of the eurozone to found the European Stability Mechanism (ESM), an international organisation located in Luxembourg, to act as a permanent source of financial assistance for member states in financial difficulty, with a maximum lending capacity of €500 billion. (wikipedia.org)
  • It replaced two earlier temporary EU funding programmes: the European Financial Stability Facility (EFSF) and the European Financial Stabilisation Mechanism (EFSM). (wikipedia.org)
  • This led to the creation, amongst other things, of loan (pejoratively called "bailout" in the media) mechanisms: the European Financial Stability Facility (EFSF) for eurozone member states and the European Financial Stability Mechanism (EFSM) for all EU member states. (wikipedia.org)
  • The two line amendment to Article 136 of the Treaty on the Functioning of the European Union (TFEU), which was approved by the European Council on 16 December 2010, reads: The member states whose currency is the euro may establish a stability mechanism to be activated if indispensable to safeguard the stability of the euro area as a whole. (wikipedia.org)
  • Due to the intergovernmental nature of the permanent lending mechanism, which was named the European Stability Mechanism (ESM), the simplified treaty revision procedure could be used for the TFEU amendment as the EU's powers were not being increased. (wikipedia.org)
  • This paper summarizes the recent progress on the study of nanofluids, such as the preparation methods, the evaluation methods for the stability of nanofluids, and the ways to enhance the stability for nanofluids, the stability mechanisms of nanofluids, and presents the broad range of current and future applications in various fields including energy and mechanical and biomedical fields. (hindawi.com)
  • The purpose of this paper will focuses on the new preparation methods and stability mechanisms, especially the new application trends for nanofluids in addition to the heat transfer properties of nanofluids. (hindawi.com)
  • Epigenetic changes affect the expression or activity of genes without changing the underlying DNA sequence - they are believed to be one mechanism by which the environment can interact with the genome. (kcl.ac.uk)
  • In the experiments an ultrafast electronic-vibrational pulse sequence is applied to a range of donor-bridge-acceptor Pt( II ) trans -acetylide assemblies, for which infrared excitation of selected bridge vibrations during ultraviolet-initiated charge separation alters the yields of light-induced product states. (nature.com)
  • This article provides an update on photodynamic therapy for the practicing dermatologist by discussing each of the essential components in sequence: mechanisms of action, common photosensitizers, typical light sources, and applications. (medscape.com)
  • This study may help us understand key interactions between components that regulate sleep behavior in people, such as how the critical delays in the basic timing mechanism get built into the system. (news-medical.net)
  • This talk explores some strategies and approaches in defining a lighter-weight subset of ACPI. (uefi.org)
  • The widely used coelenterazine-powered Renilla luciferase was discovered over 40 years ago, but the oxidative mechanism by which it generates blue photons remains unclear. (muni.cz)
  • Cytochrome c oxidase, photo receptors on your mitochondria, capture photons of red and near-infrared light. (truthseekerforum.com)
  • As explained by Whitten, there are specific bioactive wavelengths, and they work through different mechanisms. (truthseekerforum.com)
  • These mechanisms are complex and involve several immunological, genetic and viral factors. (pasteur.fr)
  • STED microscopy: The excitation light beam (EXC beam, in blue) is steered by a mirror through the objective lens, and due to diffraction is focused to a spot ca. 200 nm in diameter on the sample. (mpg.de)
  • The excitation light excites fluorescent markers which tag molecules of interest (e.g. proteins) in the sample. (mpg.de)
  • By scanning this blue excitation spot over the sample (the cell) and recording the emitted fluorescent light with a computer, one can form an image of the sample. (mpg.de)
  • It was recently shown that infrared light excitation of intramolecular vibrations can radically change the efficiency of electron transfer, a fundamental chemical process. (nature.com)
  • Photodynamic therapy (PDT) involves the use of photochemical reactions mediated through the interaction of photosensitizing agents, light, and oxygen for the treatment of malignant or benign diseases. (medscape.com)
  • Both trimeric light-harvesting complex II (LHCII) and monomeric LHC proteins have been indicated as site(s) of the heat-dissipative reactions. (lu.se)
  • By looking at infected but asymptomatic patients, this study can help us understand the mechanisms that prevent the development of symptoms following infection. (pasteur.fr)
  • Clinical evidence supports the beneficial effect of light therapy on several diseases, including depression, cognitive dysfunction, chronic pain, and sleep disorders. (iasp-pain.org)
  • In this review, we critically evaluate current clinical evidence showing the beneficial effects of light therapy on diseases. (iasp-pain.org)
  • To identify the internal mechanisms used to control dengue virus infection in asymptomatic patients, scientists from the Institut Pasteur in Paris, the Institut Pasteur in Cambodia, the CNRS and Inria examined the composition of blood serum, immune cells and the gene expression profile in asymptomatic Cambodian children infected with the dengue virus and compared them to those of patients presenting with clinical signs. (pasteur.fr)
  • New research from a multidisciplinary team helps to illuminate the mechanisms behind circadian rhythms, offering new hope for dealing with jet lag, insomnia and other sleep disorders. (news-medical.net)
  • Clear disease mechanisms and targets for the rare genetic disorders provide a window that can help us establish a platform to develop new drugs for both the rare and common disorders. (northwestern.edu)
  • Once we know more about the interplay between Bax and Bcl-2 and how it relates to this mechanism, we'll have a more complete picture of a process that is fundamental to human life. (webindia123.com)
  • The utility model relates to a generator and particularly relates to an indicating lamp mechanism at the top end of a generator. (google.com)
  • The utility model relates to a kind of generator, especially relates to a kind of generator top indicator light mechanism. (google.com)
  • Activation follows a spring-loaded mechanism not requiring further translation of other cellular factors in oocytes and is associated with unfolding of the inhibitory structure that blocks the tetramerization interface. (elifesciences.org)
  • The interaction between the proteins is then modulated and the ability of light to reset the oscillation is changed, thus altering the circadian clock and extending the period of the fly's dormancy, which helps it survive the winter. (news-medical.net)
  • Our findings give us an insight into the biological mechanism mediating the interaction between gene and environment in autism spectrum disorder. (kcl.ac.uk)
  • The experiments, augmented by quantum chemical calculations, reveal a complex combination of vibronic mechanisms responsible for the observed changes in electron transfer rates and pathways. (nature.com)
  • Another aspartate on the rim of the catalytic pocket fine-tunes the electronic state of coelenteramide and promotes the formation of the blue light-emitting phenolate anion. (muni.cz)
  • Jianjun Qu et al, Mechanisms of the formation of wind-blown sand hazards and the sand control measures in Gobi areas under extremely strong winds along the Lanzhou-Xinjiang high-speed railway, Science China Earth Sciences (2022). (phys.org)
  • Even the subject of melanoma is rife with misunderstanding because there is research showing, mechanistically, that if you expose cells in a Petri dish to lots of UV light, you can absolutely induce DNA damage and induce cancer formation. (truthseekerforum.com)
  • Different mechanisms have been proposed: energy transfer to a lutein quencher in trimers, formation of a zeaxanthin radical cation in monomers. (lu.se)
  • Near ultraviolet and blue light may also cause the formation of cataract [7]. (who.int)
  • By studying a genetic mutation in patients with a rare Parkinson's-like disorder, Northwestern Medicine scientists are working to to understand the mechanisms behind the more common form of the disease. (northwestern.edu)
  • Scientists know quite a lot about the mechanism of the repair. (sciencedaily.com)
  • Revenue Allocation Mechanisms in Post-Conflict Cou. (idea.int)
  • One of the particularities of what is currently being negotiated between Saudi Arabia and Ansar Allah is that the parties are contemplating establishing a revenue allocation mechanism in the absence of an overarching constitutional or political framework. (idea.int)
  • The U.S. Embassy fully supports the temporary freezing of oil revenues in the National Oil Corporation (NOC) account at the Libyan Foreign Bank (LFB) until there is agreement on a revenue management mechanism. (libyaherald.com)
  • Porphyrins derived from ALA are mainly localized in the vicinity of mitochondria, which can lead to apoptosis or necrosis of malignant cells upon light exposure. (medscape.com)
  • Regular exposure, on the other hand, ameliorates this risk, as it engages innate adaptive systems in your skin, your melanin in particular, that are explicitly designed to prevent DNA damage from UV light exposure. (truthseekerforum.com)
  • Just as we require adequate nutrients from the food we eat, just as our bodies require physical movement to express normal cell function, we also require adequate light exposure to express normal cell function. (truthseekerforum.com)
  • The present investigation was undertaken on rats to demonstrate the structural changes that took place after the exposure of the gingiva to a dental visible light curing unit. (who.int)
  • This article discusses research results of studies that shed light on possible mechanisms through which low back injuries may occur and how this knowledge can be leveraged to reduce the risk of low back pain. (cdc.gov)
  • The two mechanisms described above appear at stages of denervation where tonic DA levels and tonic receptor occupancy appear normal. (jneurosci.org)
  • Neurofilament light chain has emerged as a leading candidate with enormous potential to aid ALS therapy development. (medscape.com)
  • The potential of blood neurofilament light as a marker of neurodegeneration for Alzheimer's disease. (medscape.com)
  • After adjusting for maternal, child, and environmental covariates, maternal metabolic syndrome classification during pregnancy was associated with children's LIT domain through direct effects of maternal metabolic health and indirect effects of cord blood markers (total effects), and COM and PSE domains via changes only in a child's cord blood markers (total indirect effects). (biomedcentral.com)
  • The utility model provides a kind of generator top indicator light mechanism, it mainly is to solve the existing generator of prior art in the process of operation, can only be by knowing the ruuning situation of generator in the other screen of machine or the Central Control Room, and can't in factory building, know the technical problem of the ruuning situation etc. of generator. (google.com)
  • The effects of drugs acting on cerebral 5-hydroxytryptaminergic mechanisms on amphetamine (AM) and apomorphine (APO) induced turning in mice with unilateral lesions of the nigro-striatal dopamine terminals (NSDT) were studied. (erowid.org)
  • In mediation models, significant total effects were found for MetS associations with children's development in the LIT domain at age 5. (biomedcentral.com)
  • The results allow concluding that the dominant mechanism responsible for absorption in titanium dioxide films in the near-infrared range of the spectrum is the deviation from the stoichiometric composition. (finechem-mirea.ru)
  • For the treatment of acne , preferential targeting of sebaceous glands and Propionibacterium acnes reduction are believed to be the main mechanisms involved. (medscape.com)
  • Germ cells - from which egg cells and sperm cells develop - are particularly vulnerable as they contain sensitive quality control mechanisms that kill any cell that contain damaged DNA. (elifesciences.org)
  • Top-down strategies are thought to occur in more novice meditators, where there is an emphasis on attentional control and thus, top-down executive mechanisms. (frontiersin.org)
  • The Mechanism should incorporate agreement on priority expenditures, transparency measures, and steps to ensure oversight and accountability. (libyaherald.com)
  • Blue light, Crane said, changes the chemistry and structure of cryptochrome's flavin cofactor, which allows the protein to bind the TIM protein and inhibit TIM's ability to repress gene expression and thereby reset the oscillation. (news-medical.net)
  • Visible light in the blue region of the spectrum has gained popularity as a source over ultraviolet light because of its ability to produce a greater depth of polymerization [3], and to avoid possible eye damage [4,5]. (who.int)
  • Another mechanism of action is related to the benefits of hormesis and the transient spike in reactive oxygen species. (truthseekerforum.com)
  • The update sections of each chapter briefly highlights and, in some cases, slightly modifies these findings in light of one additional year of hospitalization data, two additional years of mortality, prevalence, and incidence data, and three additional years of Medicare data on end-stage renal disease. (cdc.gov)
  • Cilia also play a role in the development of the bones, although the mechanism is not well understood. (medlineplus.gov)
  • Because the photosensitizer is preferentially absorbed by hyperproliferative tissue and the light source is directly targeted on the lesional tissue, photodynamic therapy achieves dual selectivity, minimizing damage to adjacent healthy structures. (medscape.com)
  • The exact mechanisms involved in ALA photodynamic therapy for the treatment of photoaging are not well known, but increased collagen synthesis has been demonstrated following ALA photodynamic therapy. (medscape.com)
  • In this interview, Ari Whitten, author of "The Ultimate Guide to Red Light Therapy," reviews the mechanics and basic benefits of red light and infrared light. (truthseekerforum.com)
  • Light-sensing cells (photoreceptors) in the retina also contain cilia, which are essential for normal vision. (medlineplus.gov)