• We constructed Drosophila melanogaster bacterial artificial chromosome libraries with 21-kilobase and 83-kilobase inserts in the P[acman] system. (nih.gov)
  • Drosophila melanogaster is a species of fly (the taxonomic order Diptera) in the family Drosophilidae. (wikipedia.org)
  • Drosophila melanogaster flies can sense air currents with the hairs on their backs. (wikipedia.org)
  • Drosophila melanogaster is a holometabolous insect, so it undergoes a full metamorphosis. (wikipedia.org)
  • Genetic evidence for adaptation-driven incipient speciation of Drosophila melanogaster along a microclimatic contrast in "Evolution Canyon," Israel. (nih.gov)
  • Divergence of Drosophila melanogaster repeatomes in response to a sharp microclimate contrast in Evolution Canyon, Israel. (nih.gov)
  • Naturally occurring transposable elements disrupt hsp70 promoter function in Drosophila melanogaster. (nih.gov)
  • Inducing extra copies of the Hsp70 gene in Drosophila melanogaster increases energetic demand. (nih.gov)
  • We have hybridized Drosophila melanogaster DNA sequences to polytene chromosomes of D. silvestris. (hawaii.edu)
  • Light-induced pigment granule migration in the retinular cells of Drosophila melanogaster. (cdc.gov)
  • The dependence of pigment granule migration (PGM) upon the receptor potential was examined using several strains of electroretinogram (ERG)-defective mutants of Drosophila melanogaster. (cdc.gov)
  • In Drosophila melanogaster, this is most clearly observed in ancestral African populations. (ku.edu)
  • Balancing selection also acts on AMPs in Drosophila mauritiana, an isolated island endemic separated from D. melanogaster by about 4 Myr of evolution. (ku.edu)
  • Hence, we conducted thermal preference (Tp) assays and tested if infection status and genetic variation in endosymbiont bacterium Wolbachia affected temperature choice of Drosophila melanogaster. (unifr.ch)
  • Research on this topic has been greatly facilitated by using powerful genetic model insects like Drosophila melanogaster, and more recently by advances in genome modification technology, notably CRISPR/Cas9. (ugent.be)
  • A method for efficient detection and rapid molecular identification of genes in Drosophila melanogaster. (kit.jp)
  • FAK suppressed RTKs signalling in Drosophila melanogaster epithelia by impairing MAPK pathway. (gla.ac.uk)
  • Here, we investigated, in females of both D. melanogaster and D. nigrosparsa , the gene expression between animals uninfected and infected with w Mel, using RNA sequencing to see if the two Drosophila species respond to the infection in the same or different ways. (nature.com)
  • Structure of a specific alcohol-binding site defined by the odorant binding protein LUSH from Drosophila melanogaster. (expasy.org)
  • Using the genetic amenability of Drosophila melanogaster we generated tumours with specific genotypes in the living animal and carried out a detailed systematic loss-of-function analysis to identify numerous conserved genes that enhance or suppress epithelial tumour progression. (nottingham.ac.uk)
  • Drosophila melanogaster is an established model for neuroscience research with relevance in biology and medicine. (caltech.edu)
  • We evaluated the impact of curcumin on life span, fecundity, feeding rate, oxidative stress, locomotion, and gene expression in two different wild-type Drosophila melanogaster strains, Canton-S and Ives, under two different experimental conditions. (escholarship.org)
  • When females of Drosophila melanogaster and males of Drosophila simulans are mated, the male progeny are inviable, whereas the female progeny display manifold malformations and are sterile. (gatech.edu)
  • however, it has not yet been reported in adult Drosophila melanogaster. (lu.se)
  • Drosophila melanogaster is an apt model organism to decipher these behavioural paradigms. (who.int)
  • Although arthropods represent the largest and most diverse animal group, most other Fox genes have not been investigated in detail, not even in the arthropod model species Drosophila melanogaster. (lu.se)
  • Drosophila is a valuable experimental organism can be used as a reverse genetics model. (gla.ac.uk)
  • Reverse genetics has been applied to identify novel coding gene function in Drosophila tubules. (gla.ac.uk)
  • Reverse genetics has been applied to Drosophila to achieve a gene knockdown and overexpression by using the unique Gal4/UAS system to achieve the novel gene knockdown or overexpression in specific tissue and cell types. (gla.ac.uk)
  • Drosophila serido was described in 1977 by VILELA & SENE, and in the following years populations of this species from several regions were studied by means of several genetic markers. (scielo.br)
  • We describe Drosophila antonietae (previously classified as D. serido type D by SILVA & SENE, 1991 and references thereafter) and Drosophila gouveai (previously classified as D.serido type B by SILVA & SENE, 1991 and references thereafter), in terms of morphological, genetic and ecological differences. (scielo.br)
  • By altering intracellular Ca 2+ and InsP 3 levels through genetic means, we now show that signaling through the InsP 3 R is required at multiple steps for generating the neural circuit required in air puff-stimulated Drosophila flight. (jneurosci.org)
  • We also discuss an experimental framework that may circumvent current limitations while retaining the genetic versatility and robustness that Drosophila has to offer. (ugent.be)
  • Douris V, Denecke S, Van Leeuwen T, Bass C, Nauen R, Vontas J. Using CRISPR/Cas9 genome modification to understand the genetic basis of insecticide resistance : Drosophila and beyond. (ugent.be)
  • Given the versatility of Drosophila as a model organism for genetic screening and analysis, our results suggest that high-throughput behavioral screenings of adult flies can become a valuable tool for investigating the mechanisms behind PPI. (lu.se)
  • We employed conditional translating ribosome affinity purification (TRAP) followed by RNA sequencing (TRAP-seq) for transcriptome profiling of DA neurons in transgenic Drosophila lines expressing human PARIS wild type (WT) or mutant (C571A). (nature.com)
  • RNA-seq has been chosen to investigate Drosophila Malpighian (renal) tubules to identify novel genes following a three- way comparison between three popular transcriptome profiling methods. (gla.ac.uk)
  • In the hybrid females, we find abnormal levels of messenger RNA for a large fraction of the Drosophila transcriptome. (gatech.edu)
  • Two types of novel gene have been found in Drosophila tubules, coding genes and noncoding genes. (gla.ac.uk)
  • Drosophila expression arrays and Drosophila tiling arrays all suffered from cross-hybridization, miss target detection and hybridization background noise, and also have low dynamic range for detecting lowly and highly expressed genes. (gla.ac.uk)
  • Poly(A) selected RNA-seq has been used as a discovery tool for searching novel genes in Drosophila Malpighian tubules in this thesis. (gla.ac.uk)
  • A TopHat and Cufflinks pipeline has been used as an analytical pipeline for novel gene discovery and differential gene expression analysis between Drosophila tubules and whole flies in order to find the tubule-enriched genes. (gla.ac.uk)
  • Antimicrobial peptides (AMPs) are innate immune effector genes, playing a key role in pathogen clearance in many species, including Drosophila. (ku.edu)
  • In Drosophila , the BX-C cluster contains the three most posterior Hox genes, where their collinear activation incorporates progressive replacement of histone modifications, reorganization of 3D chromatin architecture and sequential activation of boundary elements and cis -regulatory regions. (biorxiv.org)
  • nov. are members of the D. buzzatii cluster of the D. repleta species group of the genus Drosophila. (scielo.br)
  • The serido sibling set is part of the buzzatii cluster ( buzzatii complex) of the genus Drosophila . (scielo.br)
  • The results support Muller's hypothesis that the chromosomal elements have been largely conserved in the evolution of the genus Drosophila. (hawaii.edu)
  • Here, using a microfluidic platform, we exposed a small segment of the axons of embryonic Drosophila motor neurons to specific cytoskeletal disruption drugs. (illinois.edu)
  • Drosophila ciD encodes a hybrid Pangolin/Cubitus interruptus protein that diverts the Wingless into the Hedgehog signaling pathway. (uzh.ch)
  • Unlike mammals that have four TIF1 members, Drosophila only encodes one member of the family, Bonus. (elifesciences.org)
  • In Drosophila, males instinctively pursue females with a lengthy and elaborate courtship ritual triggered by activation of sexually dimorphic P1 interneurons. (cdc.gov)
  • In direct contrast, here we demonstrate that much of the pattern variability in Drosophila courtship song can be explained by taking into account the dynamic sensory experience of the male. (zotero.org)
  • Mutants in the gene encoding the InsP 3 R ( itpr ) in Drosophila exhibit a range of defects including altered wing posture, increased spontaneous firing, and loss of rhythmic flight patterns in response to an air puff stimulus. (jneurosci.org)
  • In Drosophila RIM mutants, there is a large decrease in evoked synaptic transmission because of a significant reduction in both the clustering of Ca 2+ channels and the size of the readily releasable pool of synaptic vesicles at active zones. (jneurosci.org)
  • Here we identify Drosophila RIM (Rab3 interacting molecule) and demonstrate that it localizes to active zones at the larval neuromuscular junction. (jneurosci.org)
  • We demonstrate that isogenic flies infected with Wolbachia preferred lower temperatures compared with uninfected Drosophila. (unifr.ch)
  • Our data not only demonstrate that Drosophila song production is not a fixed action pattern, but establish Drosophila as a valuable new model for studies of rapid decision-making under both social and naturalistic conditions. (zotero.org)
  • To validate our findings, we demonstrate that PPI in Drosophila can be partially reverted by the N-methyl D-aspartate (NMDA) receptor antagonist MK-801, known for inducing sensorimotor gating deficits in rodent models. (lu.se)
  • Here, this model was now tested in the Drosophila background. (uni-marburg.de)
  • The results of this work were used in the assembly of a working model for the molecular mechanism of the H-P switch in Drosophila. (uni-marburg.de)
  • In a Drosophila disease model lacking Parkin (park(25) null mutant), we tested the effect of zinc supplementation. (uzh.ch)
  • Here, we use both a linear model and control-gene-based approach to show that balancing selection is an important force shaping AMP diversity in Drosophila. (ku.edu)
  • In vertebrates this subfamily contains four proteins: TIF1α/TRIM24, TIF1β/TRIM28, TIF1γ/TRIM33, and TIF1δ/TRIM66, while only one protein, Bonus (Bon), is present in Drosophila , making it an attractive model to understand the conserved functions of TIF1 proteins. (elifesciences.org)
  • In this paper, we propose a dynamical model for the molecular events underlying these early nuclear division cycles in Drosophila. (vt.edu)
  • In a light/dark T-maze, approximately 70% of a group of Drosophila fruit flies choose the bright arm of the T-Maze, while the remaining 30% walk into the dark. (uni-regensburg.de)
  • Drosophila tiling microarrays also have a high false-positive detection rate, which may lead to overestimate the transcriptional activities of the genome. (gla.ac.uk)
  • This suggests that balancing selection may be broadly acting to maintain adaptive diversity in Drosophila AMPs, as has been found in other taxa. (ku.edu)
  • In this study, we use anterior-posterior (AP) segmentation in the fruit fly ( Drosophila ) to understand how gene regulation dynamics control noise. (soton.ac.uk)
  • This important study advances our understanding of the functions and regulation of the Drosophila transcriptional regulator Bonus, an ortholog of mammalian TIF1 family members. (elifesciences.org)
  • The Wolbachia strain w Mel was recently found to increase locomotor activities and possibly trigger cytoplasmic incompatibility in the transinfected fly Drosophila nigrosparsa . (nature.com)
  • This article incorporates text from the United States National Library of Medicine, which is in the public domain. (wikipedia.org)
  • Here, we extend this nomenclature to the adult thoracic and abdominal neuromeres, the ventral nerve cord (VNC), to provide an anatomical description of this major component of the Drosophila nervous system. (caltech.edu)
  • We addressed this question by studying the spatial restriction of melanization in the Drosophila wing. (biologists.com)
  • The aim is to create a nomenclature, definitions, and spatial boundaries for the Drosophila VNC that are consistent with other insects. (caltech.edu)
  • Login is currently restricted to library staff. (caltech.edu)
  • We discuss this progress for a series of different insecticide targets, but also report a number of unsuccessful or inconclusive attempts that highlight some inherent limitations of using Drosophila to characterize resistance mechanisms identified in arthropod pests. (ugent.be)
  • Three-way analysis of Drosophila expression microarrays, Drosophila tiling micrarrays and Drosophila RNA-seq reveal that most gene expression levels are well correlated between the three technologies. (gla.ac.uk)
  • Drosophila expression microarrays and RNA-seq are correlated better than the correlation between Drosophila tiling microarrays and RNA-seq. (gla.ac.uk)
  • However, Drosophila expression microarrays and tiling microarrays still remain useful. (gla.ac.uk)
  • Drosophila Malpighian (renal) tubules are important epithelial tissue in which to study transport mechanisms. (gla.ac.uk)
  • The D. willistoni 17A2 strain was collected in 1991 in the state of Rio Grande do Sul, Brazil (30°05'S, 51°39'W), and has been maintained since then at the Drosophila laboratory of UFRGS. (scielo.br)
  • Here is how the modern biologist can go to his electronic library, and search out software titles: Go to the biology software and data library at Indiana U: gopher ftp.bio.indiana.edu 1. (bio.net)
  • A connection between DNA breaks and topoisomerase activity appears not to exist in Drosophila spermatids. (uni-marburg.de)
  • In Drosophila , InsP 3 R activity is required in aminergic interneurons during pupal development for normal flight behavior. (jneurosci.org)
  • IMSEAR is the collaborative product of Health Literature, Library and Information Services (HELLIS) Network Member Libraries in the WHO South-East Asia Region. (who.int)
  • Pages on library web site, for example research guides, library policies and procedures, hours and events. (unlv.edu)