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  • mRNA
  • b. to measure mRNA hepcidin expression in two different hepatic cell lines (HepG2 and Huh-7) exposed to patients and controls sera to assess whether circulating factors could influence hepcidin transcription in different pathological conditions. (pubmedcentralcanada.ca)
  • HAMP mRNA expression in Huh-7 cells exposed to sera form C-Donors, HFE -HH and THAL reproduced, at lower level, the results observed in HepG2, suggesting the important but not critical role of HFE in hepcidin regulation. (pubmedcentralcanada.ca)
  • hemoglobin
  • Mice with increased hepcidin expression also demonstrated an increase in the lifespan of their red cells, reversal of ineffective erythropoiesis and splenomegaly, and an increase in total hemoglobin levels. (jci.org)
  • protein
  • Insulin treatment corrects hepcidin but not YKL-40 levels in persons with type 2 diabetes mellitus matched by body mass index, waist-to-height ratio, C-reactive protein and Creatinine. (sigmaaldrich.com)
  • Patients in all three groups were matched by Body Mass Index, Waist-to-Height Ratio, C-Reactive Protein and creatinine levels. (sigmaaldrich.com)
  • There are few studies analysing the relationship between hepcidin transcript and related protein expression profiles in humans. (pubmedcentralcanada.ca)