• However, the relationship between adiposity and cancer remains poorly understood at the mechanistic level. (usda.gov)
  • Trunk-to-limbs, trunk-to-total, abdominal-to-trunk skinfold ratios, and total adiposity were calculated. (human-biology-and-public-health.org)
  • Total adiposity, which was also measured by clinical CT scans, represented the sum of visceral adipose tissue, subcutaneous adipose tissue, and intramuscular adipose tissue each individual patient carried. (medscape.com)
  • The mortality risk was highest among patients with both sarcopenia and high levels of total adiposity, among whom the relative risk for mortality was 89% higher than that in patients without sarcopenia and with low levels of total adipose tissue. (medscape.com)
  • Indeed, only patients in the highest tertile of total adipose tissue but without sarcopenia had a significantly higher risk for death by some 40% compared with those with low total adiposity without sarcopenia. (medscape.com)
  • Conversely, the risk for death was increased regardless of the level of total adiposity among patients with sarcopenia compared with patients with no sarcopenia and low total adiposity levels. (medscape.com)
  • Studies using higher dose, pharmacologic growth hormone (GH) administration have resulted in reduced visceral adiposity in this population, but are associated with increased insulin resistance and side effects [10-13]. (natap.org)
  • To compare objectively measured habitual physical activity, sedentary time, and indices of adiposity in adolescents from rural and urban areas of Kenya. (humankinetics.com)
  • Rural Kenyan adolescents are significantly more physically active (and less sedentary) and have lower indices of adiposity compared with urban adolescents and this is a likely refection of the impact of urbanization on lifestyle in Kenya. (humankinetics.com)
  • changes of serum resistin were compared with changes of BMI, body composition, fat distribution, and several indices of insulin sensitivity derived from plasma glucose and serum insulin levels measured during 75-g oral glucose tolerance test. (elsevierpure.com)
  • Ciliary neurotrophic factor is increased in the plasma of patients with obesity and its levels correlate with diabetes and inflammation indices. (nih.gov)
  • Insulin Resistance-Varying Associations of Adiposity Indices with Cerebral Perfusion in Older Adults: A Population-Based Study. (bvsalud.org)
  • Several adiposity indices were proposed to assess obesity , while their linkage with brain health in older adults remained unclear. (bvsalud.org)
  • Here we aimed to examine the associations of adiposity indices with global and regional cerebral blood flow (CBF) in older adults , while considering insulin resistance . (bvsalud.org)
  • We estimated eight adiposity indices based on anthropometric measures . (bvsalud.org)
  • We determined the predictive value of mid-life adiposity, including body mass index and tricep and subscapular skinfold thickness, on the risk of developing dementia in a large multiethnic cohort of men and women followed for an average of 27 years. (bmj.com)
  • For excess general adiposity, triceps and subscapular skinfold above the 90th percentile were simultaneously considered. (bvsalud.org)
  • Association between CNTF Polymorphisms and Adiposity Markers in European Adolescents. (nih.gov)
  • Male adolescents with excess peripheral, central and general adiposity were more likely of having high systolic blood pressure and high diastolic blood pressure when presenting high general adiposity. (bvsalud.org)
  • Are Physical Activity and Sedentary Screen Time Levels Associated With Food Consumption in European Adolescents? (who.int)
  • These factors, alone and in combination with each other, could have pre-determined effects on a child's size, adiposity and future metabolic outcomes later in life. (news-medical.net)
  • In patients, VAT levels were correlated with age, disease duration and occurrence of metabolic syndrome and cardiac dysfunction. (nih.gov)
  • Other clinical features, such as Kussmaul respiration and altered level of consciousness due to metabolic derangement, are commonly observed during acute deterioration. (medscape.com)
  • Conversely, after transfer to short, winter-like photoperiods, these hamsters become sexually quiescent, while their adiposity increases ( Bartness and Wade, 1985 ). (frontiersin.org)
  • Tandem mass spectrometry analysis of plasma from obese mice under CR showed no difference in Cur metabolite levels between groups supplemented with Cur alone or combined with Pip. (springer.com)
  • Middle-aged and older men (≥50 years), especially those who are obese and suffer from comorbidities, not uncommonly present with clinical features consistent with androgen deficiency and modestly reduced testosterone levels. (medscape.com)
  • In contrast, many middle-aged and older men (defined here as aged 50 years or older), especially when obese and suffering from comorbid illness, present with clinical features resembling organic androgen deficiency and modestly to occasionally severely low testosterone levels, yet they do not have recognizable intrinsic structural HPT pathology. (medscape.com)
  • 4 In the United Kingdom Prospective Diabetes Study, a 1 percent lower A1C level was associated with a 21 percent lower risk of death related to diabetes, a 14 percent lower risk of myocardial infarction, and a 37 percent lower risk of microvascular complications. (aafp.org)
  • 6 Therefore, although it has been proven that among persons with diabetes who have lower A1C levels there are fewer deaths, heart attacks, and microvascular complications, there is not yet conclusive evidence that lowering A1C levels through exercise leads to a corresponding risk reduction in patient-oriented outcomes (a benefit that has been demonstrated for tight control of blood pressure and lipid levels in patients with diabetes). (aafp.org)
  • This article discusses an overview of the risk factors, cellular and genetic levels of the process, immune response, complications, and treatment of NASH. (nursingcenter.com)
  • Abdominal adiposity is a risk factor for obesity-related complications, and there is increasing evidence that abdominal adiposity may be a contributing factor to complications not related to adiposity at the waist (4,5). (cdc.gov)
  • Genome-wide association studies have identified common genetic variants robustly associated with anthropometric indicators of adiposity. (nature.com)
  • The aim of our study was to examine the relationship of serum resistin level to body composition, insulin resistance, and related obesity phenotypes in humans. (elsevierpure.com)
  • Assessment of obesity before old age may be a more accurate representation of adiposity as the ratio of lean to fat mass changes with ageing, 5 resulting in a decreased body mass index. (bmj.com)
  • 8 Obtaining weight measurements many years before the onset of dementia, as well as other measures of adiposity, would provide stronger evidence of causality between obesity and increased risk of dementia. (bmj.com)
  • The Amish we studied had very high levels of physical activity, which may contribute to their low prevalence of obesity. (lww.com)
  • However, in animals and adults in the United States, serum cholesterol and triglyceride levels were paradoxically reduced, despite the obesity ( 1 - 4 ). (cdc.gov)
  • As we continue to investigate precision-based interventions to intercept the link between obesity and cancer, it is imperative to reiterate the importance of maintaining a healthy weight and lifestyle from an early age and incorporate it widely into cancer prevention strategies at all levels with immediate implementation," the editorialists conclude. (medscape.com)
  • The aim is to determine the body mass index (BMI), the risk level, and the presence of truncal obesity. (medscape.com)
  • Researchers from the Singapore Institute for Clinical Sciences assessed the association of maternal lifestyle and environmental factors, fetal epigenetics, and fetal genetics on birth weight and adiposity in early childhood. (news-medical.net)
  • The clinical significance of a 0.6 percent reduction in A1C levels resulting from exercise might be extrapolated by a comparison with the average 1 to 2 percent reduction achieved with most classes of oral hypoglycemic agents. (aafp.org)
  • Working with Dr Stuart, she will undertake clinical research on fetal adiposity in utero in the Ultrasound Departments of both Mount Carmel Hospital and the Coombe Women & Infants University Hospital. (ucd.ie)
  • Daily probiotic yogurt consumption may improve energy metabolism and reduce body fat levels by up to 4%, say results of a placebo-controlled, double-blind cross-over clinical trial in Canada. (nutraingredients.com)
  • Testosterone therapy should be considered primarily for men who have significant clinical features of androgen deficiency and unequivocally low testosterone levels. (medscape.com)
  • Male hypogonadism is a syndromic diagnosis based on consistent clinical symptoms and signs of androgen deficiency and repeatedly low serum testosterone levels. (medscape.com)
  • A new article, published in the journal BMC Medicine, reports the largest epigenome-wide association study to date that provides evidence that factors contributing to childhood adiposity (level of body fat) begin before birth and are influenced by mother's lifestyle, and fetal genetic and epigenetic factors. (news-medical.net)
  • Analysis of fetal DNA (from umbilical cord blood) revealed that genetic markers commonly associated with high BMI in adults were detectable in fetal DNA and found to be related to birth weight and adiposity in childhood. (news-medical.net)
  • DNA methylation patterns from fetal DNA revealed several regions of DNA that were associated with BMI at birth and child weight during early development (between 3 and 48 months years old).The methylation pattern at three of these identified regions were also associated with maternal factors including smoking, blood glucose levels and BMI. (news-medical.net)
  • For example, we are both committed to investigating fetal adiposity in utero. (ucd.ie)
  • This new research will examine the relationship between maternal sugar levels during pregnancy and fetal adiposity in utero. (ucd.ie)
  • Prospectively, TEE, AEE, physical activity level, and MVPA, but not sedentary activity, were positively associated with changes in BMI (P = 0.0001-0.051) and FFM (P = 0.0001-0.037), but not percent FM. (usda.gov)
  • Conclusions: TH9507 reduced truncal fat, improved the lipid profile and did not increase glucose levels in HIV-infected patients with central fat accumulation. (natap.org)
  • In this study, we assessed the effect of TH9507, a novel growth hormone releasing factor (GRF) analog, over 12 weeks in HIV-infected men and women with evidence of fat redistribution and increased truncal adiposity. (natap.org)
  • However, abdominal adiposity may be more predictive of CVD risk than BMI. (cdc.gov)
  • Incidence rates tended to be higher with increasing adiposity and serum cholesterol levels. (cdc.gov)
  • The latter exerts an independent contribution to excess adiposity over and above the potential mediating role of individual-level lifestyle and socio-economic position (SEP). (uea.ac.uk)
  • The role of the obesogenic environment on excess adiposity is more pronounced for women than men. (uea.ac.uk)
  • Overall, our results highlight that policies that aim to tackle excess adiposity should address both people and places. (uea.ac.uk)
  • Recent studies also suggest that growth hormone levels are reduced in HIV-infected patients, and correlate inversely with excess visceral fat accumulation [8,9]. (natap.org)
  • Now, through a long-term study involving thousands of women and children, researchers have found that elevated maternal blood glucose levels even below those meeting traditional GDM diagnostic criteria increase the risk of future type 2 diabetes in mothers and impaired glucose metabolism and greater excess fat in children ages 10 to 14 years post-delivery. (nih.gov)
  • Additionally, while the vet can just pull a quick blood sample and measure basal or resting levels of ACTH or insulin levels, oftentimes it's best to perform dynamic testing. (thehorse.com)
  • The BCAAs have variable effects on glucose metabolism, insulin levels, and response. (medicinenet.com)
  • Visceral fat in one's spare tire can raise insulin levels, furthering type 2 diabetes. (bcmj.org)
  • In adipocytes, the sterol regulatory element binding protein pathway is increased, resulting in increases in levels of sterol regulatory element binding protein 1 and fatty acid synthase. (cdc.gov)
  • A 65-year-old woman with new-onset type 2 diabetes and an A1C level of 8 percent wants to know if she can control her diabetes without taking medications or insulin. (aafp.org)
  • First, despite evidence that exercise reduces adiposity in patients with type 2 diabetes, exercise should not be recommended as a primary means for weight loss (particularly short-term weight loss) because of the lack of a short-term net reduction in body mass index. (aafp.org)
  • In some women, these changes can cause their blood glucose levels to rise to such a degree that they are diagnosed with and treated for a condition called gestational diabetes (GDM), a form of diabetes that is diagnosed during pregnancy and is not clearly identified as either preexisting type 1 or type 2 diabetes. (nih.gov)
  • The pertinent public health question is whether or not an individual can attenuate the influence of their genetic risk for adiposity by healthy lifestyle behaviours? (nature.com)
  • Sarcopenia, or low levels of skeletal muscle mass, is a highly prevalent though largely unrecognized risk factor for overall mortality in women with stage II and III nonmetastastic breast cancer, an observational study suggests. (medscape.com)
  • At the same time, patients in the highest tertile of adiposity had a 35% higher relative risk for death compared with patients in the lowest tertile, and this association did not vary significantly by age, BMI, cancer stage, or estrogen receptor status, the researchers add. (medscape.com)
  • Traditional approaches to diagnosing GDM in the United States include a screening test 24 to 28 weeks into pregnancy, during which women are given a sugary drink and then tested for blood glucose levels to see if they are at risk. (nih.gov)
  • Women identified as at-risk then go through further testing to see if their blood glucose levels exceed certain threshold values for diabetes. (nih.gov)
  • Studying a racially and ethnically diverse international cohort of over 23,000 pregnant women and their babies, the HAPO researchers found that elevated maternal blood glucose levels below those diagnostic of GDM were associated with increased risk of multiple adverse outcomes for the mother and child. (nih.gov)
  • Analysis of a large number of potential risk factors showed GBM cases were associated with increased dietary glucose and carbohydrate levels, low alcohol consumption including wine, and solvent exposure, especially carbon tetrachloride. (cdc.gov)
  • suggesting higher, but not diabetic levels of blood glucose confer a risk, thus, effective preventive strategies may prove successful in prediabetes. (lu.se)
  • Increased hepatic levels of glycerol 3-phosphate (3-GP) after ethanol ingestion are related to an increase in the ratio of the oxidized form of nicotinamide adenine dinucleotide (NAD + ) to the reduced form (NADH) in the liver. (medscape.com)
  • Overall, the relative contribution of demographics (age and gender) becomes less evident moving to higher quantiles of the BMI distribution, while that of obesogenic environment, individual-level lifestyle and SEP measures becoming more relevant. (uea.ac.uk)
  • New research being presented at the Annual Meeting of the European Association for the Study of Diabetes (EASD) in Hamburg, Germany (2-6 Oct) has linked infant formula and the early introduction of fizzy drinks with higher levels of body fat later in childhood. (eurekalert.org)
  • Lysophosphatidylinositol (LPI) 18:0 showed higher levels in patients with IBD than in control subjects whereas LPI 20:4 was elevated in both CRC and IBD. (nature.com)
  • However, some studies show higher levels of activation of Hedgehog pathways in patients with the most advanced fatty liver disease. (medscape.com)
  • A lower decline in control was associated with higher levels of exposure in women in the intervention group. (bmj.com)
  • female players display higher levels of adiposity compared with their male counterparts. (humankinetics.com)
  • Positional differences exist: Center players are heavier and have higher body fat levels compared with perimeter players. (humankinetics.com)
  • Therefore, this study aimed to determine the difference in heart rate variability (HRV) of Malay male young adult with their BMI and adiposity level. (inbodybwa.com)
  • The CHDS published an article in the New Zealand Medical Journal last year called Childhood predictors of adult adiposity . (otago.ac.nz)
  • In middle-aged and older men, functional (late-onset, age-related onset, or adult onset) hypogonadism is usually associated with low or normal gonadotropin levels. (medscape.com)
  • No association was observed between physical activity level and inflammatory markers. (who.int)
  • However, BMI is a crude measure of adiposity in childhood. (eurekalert.org)
  • In this study, we aimed to expand on this prior research by examining associations of infant feeding practices with a more precise measure of childhood adiposity (percent fat mass). (eurekalert.org)
  • The study's authors conclude: "Infant feeding patterns, especially shorter breastfeeding duration, early soda introduction and their joint effect, may influence body fat levels later in childhood. (eurekalert.org)
  • Eleven of 30 maternal factors, including maternal adiposity, smoking, blood glucose and plasma unsaturated fatty acid levels influenced birth weight. (news-medical.net)
  • Pinealectomy, however, totally reversed the decreased levels of insulin under short days and the photoperiodic variations in mean levels of blood glucose (i.e., reduction and increase in long and short days, respectively). (frontiersin.org)
  • Controlling maternal blood glucose levels through lifestyle change (modifications to diet and exercise) and/or with injections of the hormone insulin, if needed, can mitigate some of these risks. (nih.gov)
  • In 2008, the landmark NIH-funded Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study reported findings of health problems associated with glucose levels during pregnancy that were above normal (hyperglycemia), but not high enough to be considered diabetes. (nih.gov)
  • Strikingly, the HAPO researchers observed that even modestly elevated maternal blood glucose levels were associated with risks, which increased with maternal blood glucose levels in a linear fashion for most outcomes. (nih.gov)
  • Because HAPO only included women whose glucose levels were not high enough for a diagnosis of GDM at the time, they were not considered to have this disease and thus were not treated for it. (nih.gov)
  • these criteria include lower blood glucose level threshold values for a GDM diagnosis. (nih.gov)
  • Insulin resistance was assessed using the triglyceride - glucose index and then dichotomized into high and low levels according to the median. (bvsalud.org)
  • C-reactive protein level had a significant association with body mass index (r = 0.18), adiposity (r = 0.23), smoking (r = 0.20), carbohydrate intake (r = 0.19) and saturated fatty acid (r = 0.20). (who.int)
  • 5 However, this study did not demonstrate that therapies targeted to reduce A1C levels improved patient-oriented outcomes. (aafp.org)
  • Data on nutritional intake, physical activity level and smoking habits were collected through a questionnaire. (who.int)
  • Serum vitamin D levels were determined with high performance liquid chromatography, food intake was measured by semiquantitative frequency and nutritional status was assessed by anthropometry. (bvsalud.org)
  • In Paper III, a series of causal-inference experiments from VHU and publicly available genome-wide association study (GWAS) summary statistics were used to triangulate evidence of the direct and mediated effects by adiposity and physical activity, of macronutrient intake (fat, carbohydrates, protein and sugar) and cardiometabolic disease. (lu.se)
  • Individuals with Down syndrome (DS) have been shown to display high levels of adiposity and a unique body shape. (aahd.us)
  • 2 (16.60%), where most of the individuals with normal level were grouped. (bvsalud.org)
  • Beyond our "at the mean" analysis, Shapley decomposition combined with unconditional quantile regression analysis allow us to explore the relative contribution of small-area level proxies of the obesogenic environment as opposed to our set of individual-level characteristics, across the whole adiposity distribution. (uea.ac.uk)
  • Overall, until now, most epidemiologic studies have examined BMI at one timepoint, "missing the opportunity to delineate the contribution of adiposity throughout the life course," editorialists Shi and Cao explain. (medscape.com)
  • Regular exercise reduces A1C levels, adiposity, and triglyceride levels. (aafp.org)
  • This Cochrane review provides strong evidence that exercise programs ranging in duration from eight weeks to one year reduce A1C levels by approximately 0.6 percent, as well as reducing adipose tissue and triglyceride levels. (aafp.org)
  • 73% were women and 61% belonged to medium socio-economic level. (bvsalud.org)
  • Increased CNTF levels in adults with autism spectrum disorders. (nih.gov)
  • Although young people are more active than adults are (1), many young people do not engage in recommended levels of physical activity (47,48). (cdc.gov)
  • Inducing de-differentiation by Xbp1s overexpression promotes tumor progression despite lower adiposity. (usda.gov)
  • The purposes of this study were to characterize the physical activity (PA) levels in an Old Order Amish farming community and to examine measures of adiposity in this group. (lww.com)
  • they should be concerned about a woman's muscle level as it is as important a prognosticator as high adiposity for survival," Caan emphasized. (medscape.com)
  • Third, reductions in A1C levels were noted across a wide range of activity levels-from low-intensity, once-weekly qigong to high-intensity progressive resistance training. (aafp.org)
  • Few jobs in modern society require the same high levels of energy expenditure that were required of North American residents 150 yr ago. (lww.com)
  • 95% confidence interval (CI) 51.7 - 65.0) had dyslipidaemia, 16.3% (n=24/147) had low HDL-C levels, 53.8% (n=78/145) had high LDL-C levels and 14.9% (n=22/148) had raised TG levels. (who.int)
  • In the Paediatric Diabetes Unit at Tygerberg Hospital (TBH) correlated, while HDL particle size was negatively correlated, the practice has been to monitor fasting lipid profiles annual y in to HbA1c levels. (who.int)
  • The primary indicator was change in adiposity with a goal of 3% loss in weight across the intervention. (cdc.gov)
  • Simple baseline survey-assessment defined employees who reported room to change their dietary and physical activity patterns as well as an accurate realization of their level of excessive adiposity. (cdc.gov)
  • Serum vitamin D levels depend on sunlight, diet, and other factors. (bvsalud.org)
  • In a previous study, the RVD-hemopressin-α, an endogenous anorexigenic peptide, proved to be a negative allosteric modulator of CB1 [43] and to inhibit hypothalamic NE levels following peripheral administration despite being ineffective against DA and 5-HT levels [30]. (researchgate.net)
  • This creates a microbiome which favors fat oxidation over fat storage, by populating the gut with protective bacteria and preventing the proliferation of pathogenic bacteria, which may ultimately lead to a reduction in body adiposity and transformation of body composition. (nutraingredients.com)
  • The prostaglandin E2 (PGE2) level, brain-derived neurotrophic factor (BDNF), interleukin-10 (IL-10), and IL-1β gene expression were evaluated in the cortex. (researchgate.net)
  • In the same experimental system, IL-10 and BDNF gene expressions increased, and in HypoE22 cells, the extract decreased the extracellular dopamine level and increased the DAT gene expression due to the direct interaction of parthenolide with the DAT. (researchgate.net)
  • The mechanisms responsible for the increased adiposity are changes in gene expression of multiple enzymes and transcription factors by the virus ( 8 - 15 ). (cdc.gov)
  • Conclusions While the intervention did not improve women's diets and physical activity levels, it had a protective effect on intermediate factors-control and self-efficacy-suggesting that a more prolonged exposure to the intervention might improve health behaviour. (bmj.com)
  • Another aim was to correlate the levels of these adipokines and the severity of autistic symptoms as measured by the Social Responsiveness Scale (SRS). (karger.com)