• Parental exposure to bisphenol A (BPA) during pregnancy is associated with decreased birth weight of offspring, compared with offspring from families without parental BPA exposure in the workplace, according to researchers. (sciencedaily.com)
  • Women exposed to high levels of bisphenol A early in their pregnancy had an 83 percent greater risk of miscarriage than women with the lowest levels, according to new research. (lactobacto.com)
  • Bisphenol S (BPS), a common substitute for bisphenol A (BPA) in consumer products, may have similar toxic effects on the heart as previously reported for BPA, a new study finds. (lactobacto.com)
  • Examples include bisphenol A (BPA), polychlorinated biphenols (PCBs), perfluoroalkyl substances (PFAs) and organochlorines (OCs). (thyroid.org)
  • Bisphenol A, or BPA, is widely used to soften plastics. (cancerlive.net)
  • Bisphenol A (BPA) is a man-made compound used in polycarbonate (hard)plastics like water and baby bottles, household equipment, toys, and tin cans. (naturalfertilityandwellness.com)
  • One study shows that the endocrine disrupting chemical bisphenol-A works in a fashion that is comparable to diethylstilboestrol at the cell and developmental level and research has clearly shown that many industrial chemicals can affect thyroid function. (hindustantimes.com)
  • Chevy Chase, MD -- In utero exposure to bisphenol A (BPA) can be associated with decreased thyroid function in newborn sheep, according to a recent study accepted for publication in Endocrinology, a journal of The Endocrine Society. (clinicalnews.org)
  • Specifically, her laboratory focuses on the impact of maternal exposure to native steroids (testosterone, estradiol), and environmental pollutants such as bisphenol-A in altering developmental trajectory of fetus and programming adult reproductive and metabolic diseases. (umich.edu)
  • The much debated EDC bisphenol A (BPA) was used for a case study in a large part of this work. (5dok.org)
  • Bisphenol A (BPA) is a classic example. (bitterrootbugle.com)
  • Most BPA-free plastics contain another chemical, bisphenol S (BPS), in BPA's place. (bitterrootbugle.com)
  • Both animal and human studies have shown that BPA can pass through the placental barrier and that fetuses are likely to be exposed to similar (if not higher) levels of BPA as those of mothers, explained the researchers. (sciencedaily.com)
  • The current study used sheep, a relevant model for human pregnancy and thyroid regulation and ontogeny, and analyzed the internal exposures of the fetuses and their mothers to BPA and determined to what extent those exposures may be associated with thyroid disruption. (clinicalnews.org)
  • Although the finding needs to be confirmed by additional studies, the study provides preliminary evidence that maternal exposure to BPA during pregnancy may have an adverse effect on fetal growth, said De-Kun Li, MD, PhD, the principal investigator of the study, senior author of the new publication, and a reproductive and perinatal epidemiologist at the Kaiser Permanente Division of Research in Oakland, Calif. (sciencedaily.com)
  • Chemicals in pregnant women can cross the placenta and in some cases can accumulate in the foetus resulting in higher foetal exposure than maternal exposure. (hindustantimes.com)
  • Using both animal models and human pregnancy cohort Dr. Padmanabhan's research focuses on understanding the fetal origin of pubertal and adult reproductive and metabolic disorders. (umich.edu)
  • For the last 20 years, data has accumulated suggesting changes in pubertal timing and a possible role for exposure to endocrine disrupting chemicals (EDCs). (desdaughter.com)
  • Human evidence of altered pubertal timing after exposure to endocrine disrupting chemicals is equivocal. (desdaughter.com)
  • In 2003, the National Institute for Environmental Health Sciences (NIEHS) initiated the Breast Cancer and the Environment Research Program (BCERP) with support from the National Cancer Institute (NCI) to specifically examine whether environmental exposures during the pubertal WOS affect the timing of puberty, a risk factor for breast cancer. (biomedcentral.com)
  • This study was done to determine whether exposure to air pollution during late pregnancy affects the mother's and/or the baby's thyroid function and birth weight. (thyroid.org)
  • Janssen BG et al Fetal thyroid function, birth weight, and in utero exposure to fine particle air pollution: a birth cohort study. (thyroid.org)
  • Most investigations have focused on reproductive functions, but there is evidence that BPA might have negative effects on other endocrine systems including thyroid function. (clinicalnews.org)
  • Our study is the first to show that BPA can alter thyroid function of pregnant animals and their offspring in a long-gestation species with similar regulation of thyroid function as humans," said Catherine Viguié, PhD, of Toxalim, Research Centre in Food Toxicology in Toulouse, France and lead author of the study. (clinicalnews.org)
  • Because of the potential consequences of maternal/fetal thyroid disruption on neural and cognitive development, we think that our study warrants the need for further investigations on the effect of BPA on thyroid function. (clinicalnews.org)
  • Results showed that maternal and fetal exposure to BPA was associated with disruption of thyroid function of both the pregnant ewes throughout pregnancy and the newborns as characterized by a decrease in circulating thyroxine levels. (clinicalnews.org)
  • As a consequence, although this study clearly indicates that BPA has the potential to alter thyroid function in living pregnant animals and their offspring, it cannot be considered as fully conclusive in terms of risk for human health in the actual conditions of exposure of human populations. (clinicalnews.org)
  • So, like the chicken and egg question - does BPA help cause PCOS symptoms, or do PCOSer's just unable to eliminate toxins as effectively? (naturalfertilityandwellness.com)
  • Robust scientific evidence has emerged over the past 15 years demonstrating that preconception and prenatal exposure to toxic environmental toxins can have a profound and lasting effect on reproductive health across the life course and an analysis of National health and Nutrition Examination Survey data from 2003-2004 found that every women is exposed to 43 different chemicals. (hindustantimes.com)
  • Such fetal exposure to toxins during critical stages of development can cause permanent and irreversible brain and organ damage, not just at birth but even decades later. (inalliancepse.org)
  • A March 2015 study showed that high concentrations of BPA inhibited sperm motility and motion kinematics by significantly decreasing ATP levels in spermatozoa. (naturalfertilityandwellness.com)
  • BPA concentrations in the mother blood in this experiment were fluctuating between injections from 15 to 1 time the highest blood levels reported in pregnant women in the literature," notes Viguié. (clinicalnews.org)
  • Oxytocin didn't signal from mother to baby in either rodent model, the researchers found, and as a result, chloride built to higher concentrations than it should have inside fetal neurons. (science20.com)
  • The AT also plays a role in the toxicokinetics of POPs since it can store these chemicals for a long time and, in that sense, may be protective during acute exposure. (ecog-obesity.eu)
  • However growing evidence suggests that these chemicals can be released from the AT at a low level. (ecog-obesity.eu)
  • Dr Shruti N Mane elaborated, "Exposure to environmental chemicals is linked to various adverse health consequences, and patient exposure at any point in time can lead to harmful reproductive health outcomes. (hindustantimes.com)
  • Highlighting that exposure to some pesticides can interfere with all developmental stages of reproductive function in adult females, including puberty, menstruation and ovulation, fertility and fecundity, she said, "Most environmental chemicals have entered the marketplace without comprehensive and standardized information regarding their reproductive or other long-term toxic effects. (hindustantimes.com)
  • The series includes numerous tips for pregnant women and families to take action to reduce exposure to lead and mercury and the chemicals found in pesticides, cleaning products, plastics, paint, personal care products and the air. (littledotapp.com)
  • Chemicals called PFAS were found in high levels in the first study of female firefighter health. (pops.int)
  • Therefore, exposure to environmental pollutants such as Endocrine disrupting chemicals (EDCs) during critical periods of development can result in delayed/advanced puberty and long-term reproductive consequences. (desdaughter.com)
  • BPA and genistein are endocrine-disrupting chemicals, so they can mess with the hormones of an animal and potentially humans. (missouri.edu)
  • They used socio-communication testing to determine whether developmental exposure to these chemicals led to deficits in these behaviors, which are reminiscent of those seen in children with autism spectrum disorder (ASD). (missouri.edu)
  • Then there is the issue of chemical cocktails - the simultaneous exposure to numerous environmental chemicals to which most people and animals are currently exposed. (bitterrootbugle.com)
  • In the Sam's Choice and Acadia brands levels of some chemicals exceeded legal limits in California as well as industry-sponsored voluntary safety standards. (ewg.org)
  • Also in Walmart's Sam's Choice brand, lab tests found a cancer-causing chemical called bromodichloromethane at levels that exceed safety standards for cancer-causing chemicals under California's Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 65, OEHHA 2008). (ewg.org)
  • These same chemicals also polluted Giant's Acadia brand at levels in excess of California's safety standards, but this brand is sold only in Mid-Atlantic states where California's health-based limits do not apply. (ewg.org)
  • The long time from exposure to potentially harmful chemicals until breast cancer occurrence poses challenges for designing etiologic studies and for implementing successful prevention programs. (biomedcentral.com)
  • Adolfsson‐Erici M, Åkerman G, McLachlan MS. Measuring bioconcentration factors in fish using exposure to multiple chemicals and internal benchmarking to correct for growth dilution. (comprehensivephysiology.com)
  • Agay‐Shay K, Martinez D, Valvi D, Garcia‐Esteban R, Basagana X, Robinson O, Casas M, Sunyer J, Vrijheid M. Exposure to endocrine‐disrupting chemicals during pregnancy and weight at 7 years of age: A multi‐pollutant approach. (comprehensivephysiology.com)
  • A new study led by Mount Sinai researchers in collaboration with scientists from Cornell University and the U.S. Centers for Disease Control and Prevention, has found higher prenatal exposure to phthalates-manmade chemicals that interfere with hormonal messaging-to be connected with disruptive and problem behaviors in children between the ages of 4 and 9 years. (csn-deutschland.de)
  • But what this study suggests is that it's not enough to regulate childhood exposure to these chemicals. (csn-deutschland.de)
  • Studies to date on phthalates have been inconsistent, with some linking exposure to these chemicals to hormone disruptions, birth defects, asthma, and reproductive problems, while others have found no significant association between exposure and adverse effects. (csn-deutschland.de)
  • Contamination can occur due to exposure to e.g. pesticides or toxic chemicals in food and indoor air as many human biomonitoring programmes and projects have found out by testing breast milk on various substances. (blogspot.com)
  • Research shows that the placenta does not provide a defense against harmful chemicals, as previously thought.67 Persistent and bio-accumulative chemicals remain in the human body long after exposure and can be passed from mother to baby, in utero and via breast milk. (blogspot.com)
  • Children exposed to chemicals like EDCs, even at very low levels are more likely to develop health problems later in life such as cancer, infertility, or diabetes, particularly with exposure during certain windows of prenatal development.68 EDCs can also cause multigenerational harm. (blogspot.com)
  • A number of chemicals can interfere with normal growth, especially when exposure occurs during pregnancy, which is why babies with the highest in-utero exposures tend to be born smaller. (keepyourchildsafe.org)
  • Both epidemiological and experimental evidences demonstrate that BPA affects reproduction-related gene expression and epigenetic modification that are closely associated with infertility. (naturalfertilityandwellness.com)
  • Her research primarily focused on how genistein, a soy-derived phytoestrogen, and BPA, an industrial chemical, affects the behavior of mice. (missouri.edu)
  • Besides examining for mRNA that encodes for proteins that can act within or outside of a cell, Butler and Rosenfeld also are the first group to examine whether developmental exposure to BPA and genistein affects the expression of so-called junk RNA within the brain. (missouri.edu)
  • While other research groups have examined how BPA affects miR patterns in the placenta and testes, no previous research group has done so in the brain, even though this organ is vulnerable to early exposure to BPA and genistein. (missouri.edu)
  • Reproductive risk of toxicant exposure includes fetal effects, especially congenital anomalies. (medscape.com)
  • Hence, this chapter summarizes the biological plausibility of EDCs exposure and elucidates the mechanism of action underlying EDCs affecting the regulatory circuits of the mammalian HPG axis and reproductive function. (intechopen.com)
  • The researchers explained that BPA is believed by some to be a highly suspect human endocrine disrupter, likely affecting both male and female reproductive systems. (sciencedaily.com)
  • While their reproductive organs are being developed in utero, these hormone disruptors can wreak havoc and cause future problems for these poor little babes. (naturalfertilityandwellness.com)
  • Ovary, uterus and other reproductive organs are also targets of BPA. (naturalfertilityandwellness.com)
  • BPA exposure impairs the structure and functions of female reproductive system in different times of life cycle and may contribute to infertility. (naturalfertilityandwellness.com)
  • BACKGROUND: It has been suggested that antenatal exposure to environmental endocrine disruptors is responsible for adverse trends in male reproductive health, including male infertility, impaired semen quality, cryptorchidism and testicular cancer. (diagenode.com)
  • To mimic exposure to BPA during embryonic development, for two weeks following implantation the mice were fed BPA - in amounts in line with those seen in pregnant American women - as the cells produced humanized prostate tissue. (cancerlive.net)
  • However, in humans Thalidomide interfered with embryonic and fetal development in ways not observed in rodent tests. (asu.edu)
  • Maternal consumption of alcohol (ethanol) during pregnancy can result in a continuum of embryonic developmental abnormalities that vary depending on the severity, duration, and frequency of exposure of ethanol during gestation. (asu.edu)
  • In brief, CA-AhR-expressing plasmid and AhR-expressing plasmid were each transfected into neural stems cells in the developing cerebrum by in utero electroporation on embryonic day 14.5. (waseda.jp)
  • By injecting the mothers with bumetanide, however, the researchers were able to reduce chloride levels to their appropriate amount -- and in turn, to restore the GABA switch mechanism (it went from excitatory to inhibitory, as expected). (science20.com)
  • Frequent use of aerosol sprays and air fresheners by mothers during pregnancy is associated with higher levels of diarrhea and earache in their children. (littledotapp.com)
  • PUFAs especially DHA plays an important role in fetal brain and retina development when consumed by pregnant mothers. (ufaocity.xyz)
  • The mothers were not informed of their phthalate metabolite levels and the researchers were unaware of their exposures when testing the children. (csn-deutschland.de)
  • Funded by the U.S. National Institute of Occupational Safety and Health, this latest study adds to emerging human evidence questioning the safety of BPA, a chemical created in the production of polycarbonated plastics and epoxy resins found in baby bottles, plastic containers, the linings of cans used for food and beverages, and in dental sealants. (sciencedaily.com)
  • The scientists said their new study adds to evidence that low levels of the ubiquitous chemical, used to make polycarbonate plastic and found in some food cans and paper receipts, may affect human reproduction. (lactobacto.com)
  • Exposure of the fetus to BPA in utero is of particular concern, because the chemical, which mimics the hormone estrogen , has been linked to several kinds of cancer, including prostate cancer, in rodent models. (lactobacto.com)
  • Swan also explores links between chemical exposure in utero and later gender-related sexual behavior, citing dozens of relevant studies. (commondreams.org)
  • Concerns about BPA were initially raised in 1997, when Dr Fred vom Saall, a developmental biologist at the University of Missouri-Columbia, discovered that mice fed low doses of the chemical while pregnant gave birth to male pups that developed enlarged prostates. (archetypeltd.co.nz)
  • They exert their negative effects on the environment through two processes, long range transport, which allows them to travel far from their source, and bioaccumulation, which reconcentrates these chemical compounds to potentially dangerous levels. (wikipedia.org)
  • Exposure to this chemical - used widely in plastic products, canned goods and more - in utero has been linked to altered brain function and organ development. (bitterrootbugle.com)
  • The bottled water industry promotes an image of purity, but comprehensive testing by the Environmental Working Group (EWG) reveals a surprising array of chemical contaminants in every bottled water brand analyzed, including toxic byproducts of chlorination in Walmart's Sam's Choice and Giant Supermarket's Acadia brands, at levels no different than routinely found in tap water. (ewg.org)
  • By focusing on environmental chemical exposure during specific WOS, scientists and their community partners may identify when prevention efforts are likely to be most effective. (biomedcentral.com)
  • Infact, prenatal development is one of the most susceptible stages to health risks caused by chemical exposure. (blogspot.com)
  • It's believed that children accumulate as much as half of their lifetime cancer risk by age two, largely as a result of early chemical exposures. (keepyourchildsafe.org)
  • Chemical exposures have been known to trigger autoimmune disorders such as asthma or allergies. (keepyourchildsafe.org)
  • As a result, chemical exposures have been linked to conditions like ADHD or disruptive mood disorders. (keepyourchildsafe.org)
  • While we still know very little about the root cause of autism, one factor that has withstood the test of time is chemical exposure, which remains a leading candidate of things that contribute to autism. (keepyourchildsafe.org)
  • Weil, 1995) In fact, a number of skin conditions are related to chemical exposures. (keepyourchildsafe.org)
  • Perinatal exposure to several endocrine disruptors leads to increased body weight later in life as well as to several metabolic disorders, which may partially contribute to the obesity epidemics and interact with other risk factors. (ecog-obesity.eu)
  • The second study, published in May 2010 in the Journal of Andrology , found that increasing BPA levels in urine are associated with worsening male sexual function. (sciencedaily.com)
  • The third study, published in Fertility and Sterility , showed that an increasing urine BPA level was significantly associated with decreased sperm concentration, decreased total sperm count, decreased sperm vitality and decreased sperm motility. (sciencedaily.com)
  • Due to the retrospective nature of the study, estimated exposure levels in the past, rather than maternal urine BPA level, was used to classify the exposure dosage during the index pregnancy. (sciencedaily.com)
  • Although researchers have demonstrated that the estimated BPA exposure was correlated with current urine BPA, it is still possible that the association between BPA exposure and birth weight was impacted due to inaccurate classification of BPA exposure categories. (sciencedaily.com)
  • Previous studies have shown that people who avoided all contact with plastics or other BPA-containing objects for up to a month or more still had BPA in their urine, which means they must have come into contact with BPA in the last 24 to 48 hours, since it clears the body rather quickly,' said Prins, who is director of the UIC andrology laboratory. (cancerlive.net)
  • For the study, phthalate metabolite levels were analyzed in prenatal urine samples of a multiethnic group of 404 women who were pregnant for the first time. (csn-deutschland.de)
  • They found a significant positive association between phthalate exposure and ADHD, meaning that the higher the concentration of phthalate metabolites in the urine, the worse the ADHD symptoms and/or test scores. (csn-deutschland.de)
  • Two determinations must be made when a physician responds to a patient's concerns about a specific exposure: (1) whether any quantity of the toxicant has known adverse effects on reproduction in humans and (2) whether the substance is present in sufficient quantity to affect the patient or population exposed. (medscape.com)
  • This study is the fourth in a series published by Dr. Li and his colleagues that examine the effect of BPA in humans. (sciencedaily.com)
  • The thing is, t he BPA analogs -- and BPS is one of them -- have not been tested for safety in humans. (lactobacto.com)
  • BPS and other BPA analogs need to be evaluated before further use by humans. (lactobacto.com)
  • BPA has actually been suspected of being hazardous to humans since 1930. (naturalfertilityandwellness.com)
  • BACKGROUND: Prenatal cortisol exposure is essential for neurodevelopment. (bvsalud.org)
  • In addition to dose-related concerns, factors such as maternal genetics and metabolism and the timing of alcohol exposure during prenatal development also impact alcohol-related birth defects. (asu.edu)
  • Prenatal exposure to alcohol (ethanol) in human and animal models results in a range of alcohol-induced developmental defects. (asu.edu)
  • The study, which is the first to examine the effects of prenatal phthalate exposure on child neurobehavioral development, will be published January 28, on the Environmental Health Perspectives website. (csn-deutschland.de)
  • But it's their mother's contact with phthalate-containing products that causes prenatal exposure. (csn-deutschland.de)
  • The use of radiation for diagnostic imaging in the pregnant woman is usually associated with a high level of anxiety for the woman, her family, and, often, the physician. (medscape.com)
  • BPA acts like estrogen in the body and should be kept away from pregnant women and children in critical windows of development, according to researchers who have linked it to cancer, infertility, brain, nervous system and cardiovascular abnormalities, diabetes, obesity and other serious disorders. (naturalfertilityandwellness.com)
  • Some of the pregnant ewes received daily subcutaneous injections of BPA while the remainder were allocated to the control group. (clinicalnews.org)
  • When we get pregnant, we're routinely told to skip alcohol so our kids aren't born with fetal alcohol syndrome, and to stop smoking to reduce the risk of miscarriage, stillbirth, or Sudden Infant Death Syndrome . (inalliancepse.org)
  • Smog studies in major cities indicate that, depending on the specific pollutant and timing of exposure, a pregnant woman's exposure to high levels of outdoor air contaminants may affect the development of the fetus. (littledotapp.com)
  • The researchers administered a control, a genistein diet, a low dose BPA and a higher dose BPA diet to pregnant mice. (missouri.edu)
  • While the reasons for falling sperm counts are still being investigated, it is clear that the fetus is particularly susceptible to the effects of pollutants, and that impacts at the fetal stage of life can significantly shape the adult. (commondreams.org)
  • Our findings call into question the safety of BPA-free products containing BPS," he said. (lactobacto.com)
  • The findings of adverse effects of BPA in human tissue are highly relevant and should encourage agencies like the Food & Drug Administration to re-evaluate their policies in the near future. (cancerlive.net)
  • New Orleans, LA - Exposure to tiny air pollution particles may lead to reduced sperm production, suggests new research in mice, presented Monday, March 25 at ENDO 2019 , the Endocrine Society's annual meeting. (desdaughter.com)
  • The research demonstrates for the first time that exposure to air pollution of a large city impairs production of sperm through epigenetics, mainly in exposure after birth, Costa said. (desdaughter.com)
  • In adults, exposure may lead to cancer, high blood pressure, obesity and sperm damage. (bitterrootbugle.com)
  • On postnatal day 14, mice transfected in utero with CA-AhR, but not those transfected with AhR, exhibited drastically reduced dendritic arborization of layer II/III pyramidal neurons and impaired neuronal positioning in the developing somatosensory cortex. (waseda.jp)
  • The onset of puberty strongly depends on organizational processes taking place during the fetal and early postnatal life. (desdaughter.com)
  • The results point to less socialization among the mice exposed during the pre- and postnatal period to genistein or a low dosage of BPA. (missouri.edu)
  • Exposure to this powerful neurotoxic metal can cause permanent brain damage, nervous system disorders, behavior and learning difficulties, and hyperactivity. (inalliancepse.org)
  • Blood samples were taken from jugular blood, amniotic fluid, placenta samples and cord blood to determine levels of BPA, thyroid-stimulating hormone (TSH) and thyroxine. (clinicalnews.org)
  • The evidence of another 2015 study shows that BPA can interfere with endocrine function of hypothalamic-pituitary axis , such as by changing gonadotropin-releasing hormones (GnRH) secretion in hypothalamus and promoting pituitary proliferation. (naturalfertilityandwellness.com)
  • Prins investigated the effect of BPA on human cells by implanting human prostate stem cells taken from deceased young-adult men into mice. (cancerlive.net)
  • Adult male exposure to pesticides has been associated with altered semen quality, sterility, and prostate cancer. (hindustantimes.com)
  • Supported by epidemiological data and experimental studies, specific mechanisms have been defined linking environmental perturbations, disrupted fetal and neonatal development and adult ill-health. (mdpi.com)
  • To investigate whether exposure to atomic bomb radiation altered the prevalence of hepatitis C virus (HCV) infection or accelerated the progress toward chronic hepatitis after HCV infection, the seropositivity of antibody to hepatitis C virus (anti-HCV) was determined for 6,121 participants in the Adult Health Study of atomic bomb survivors in Hiroshima and Nagasaki. (bioone.org)
  • More research is needed to examine the effects of cumulative exposure to phthalates on child development. (csn-deutschland.de)
  • She added, "Plastic polymers could be also transformed in size (macro-, micro-, and Nano plastics) and in shape (spheres, fibres, and fragments) upon exposure to UV light, heat, or waves in the aquatic environment, or by biological degradation,it forms microplastics. (hindustantimes.com)
  • Researchers in Washington State found high levels of PCBs in the packaging of foods like cheese and cracker snack packs, macaroni and cheese, and taco shells, among others. (inalliancepse.org)
  • The amount of BPA we fed the mice was equivalent to levels ingested by the average person,' Prins said. (cancerlive.net)
  • After the tissue was allowed to mature for one month, the mice were given estrogen to mimic the naturally rising estrogen levels seen in aging men. (cancerlive.net)
  • Prins found that a third of tissue samples taken from mice fed BPA had either pre-cancerous lesions or prostate cancer, compared to only 12 percent in a control group of mice fed oil. (cancerlive.net)
  • If the prostate stem cells were exposed to BPA before implantation and again as they produced prostate tissue in the mice, 45 percent of the tissue samples had pre-cancerous lesions or cancer. (cancerlive.net)
  • She is Contact PI for the U-M Children's Environmental Health and Disease Protection Center on the theme: "Lifecourse exposures and diet: Epigenetics, maturation, and metabolic syndrome," and serves as Associate Director of the Michigan Nutrition and Obesity Research Center (MNORC). (umich.edu)
  • She is the director of pediatric endocrine research at the University of Michigan, and is the co-PI for the University of Michigan Children's Environmental Health and Disease Prevention Center on the theme, Lifecourse exposures & diet: Epigenetics, maturation & metabolic syndrome. (umich.edu)
  • Japanese scientists have found that women with Poly cystic Ovary Syndrome actually had higher serum levels in their blood than women with normal ovary function. (naturalfertilityandwellness.com)
  • We were diagnosed with a fetal syndrome called Twin-to-Twin Transfusion Syndrome. (issuu.com)
  • Because there is a disconnect between the research taking place, medical practitioners, and those that have been and will be facing a fetal syndrome diagnosis, this is where Connexions comes in. (issuu.com)
  • They arise during early fetal development and produce and maintain a man's prostate tissue throughout his life. (cancerlive.net)
  • In this revision, we focused our attention on the mechanisms of action and impact of EDCs exposure as a contributor to the present epidemics of obesity and MetS. (openbiotechnologyjournal.com)
  • Low testosterone levels in men can lead to obesity, low sex drive, and symptoms of depression. (commondreams.org)
  • Since 2009, she has been doing research in ELEMENT (Early Live Exposure in Mexico to Environmental Toxicants project) and PROGRESS (Program Research in Obesity, Growth, Environment and Social Stressors) birth cohorts. (umich.edu)
  • However, in addition to adulthood exposure, the perinatal effects are very important, since it may allow a change in the metabolic programming, promoting the further development of obesity and MetS. (openbiotechnologyjournal.com)
  • As PhD students, we found it difficult to access the research we needed, so we decided to create a new Open Access publisher that levels the playing field for scientists across the world. (intechopen.com)
  • Couples suffering from infertility or recurrent miscarriages would be best advised to reduce BPA exposure because it has the potential to adversely affect fetal development, " wrote the scientists, led by Dr. Ruth Lathi, a Stanford University associate professor of obstetrics and gynecology. (lactobacto.com)
  • Certain fetal and maternal conditions have been shown to have environmental and genetic components. (medscape.com)
  • The primary exposures include diagnostic radiographs, radiopharmaceuticals, workplace exposures, and environmental exposures such as those that occurred after the Three Mile Island and Chernobyl nuclear reactor accidents. (medscape.com)
  • The roentgen equivalent man (rem) unit of measure and sievert (Sv) unit are used to quantify radiation exposure over time (eg, environmental releases). (medscape.com)
  • The outcomes were obtained for the third trimester of pregnancy and the average exposure value was used after correction for environmental factors such as temperature and humidity. (thyroid.org)
  • According to the Environmental Working Group (EWG) website they quoted a recent study done by the CDC, and it showed that 93% of the people tested are contaminated with BPA. (naturalfertilityandwellness.com)
  • Miatta's research uses data from two Mexico City-based birth cohorts, namely: i) Early Live Exposure in Mexico to Environmental Toxicants (ELEMENT) study and ii) the Environmental Pollution and Birth Outcomes in Mexico study. (umich.edu)
  • How can harmful environmental exposures impact pregnancy? (littledotapp.com)
  • Thus, this tissue constitutes an endogenous source of chronic exposure to POPs. (ecog-obesity.eu)
  • With assistance from Jiude Mao in the Rosenfeld lab, they set out to test whether developmental exposure to BPA and genistein could alter miR decrease in ASD patients. (missouri.edu)
  • The present results indicate that over-activation of AhR perturbs neuronal migration and morphological development in mammalian cortex, supporting previous observations of impaired dendritic structure, cortical dysgenesis, and behavioral abnormalities following perinatal dioxin exposure. (waseda.jp)
  • There is increasing evidence that phthalate exposure is harmful to children at all stages of development," said Stephanie Engel, PhD, lead study author and Associate Professor of Preventive Medicine at Mount Sinai School of Medicine. (csn-deutschland.de)
  • The researchers explained that it is possible that offspring in this group had relatively higher levels of in-utero BPA exposure than those in other groups. (sciencedaily.com)
  • Spouses of exposed fathers, although not directly exposed to BPA in the workplace, were more likely to have a higher BPA exposure level than women in the unexposed group. (sciencedaily.com)
  • Higher maternal serum cortisol levels were associated with higher prevalence of offspring ASD traits at three years of age in the total study cohort and in boys after stratifying for offspring sex. (bvsalud.org)
  • The more BPA detected in the women's blood, the higher their risk of miscarriage, according to the researchers. (lactobacto.com)
  • The EPA confirms that albacore contains higher mercury levels than canned light tuna. (ufaocity.xyz)
  • The dendritic cells of elite controllers, however, were found to contain higher levels of HIV DNA, probably because of limited expression of a protein called SAMDH1 that usually blocks reverse transcription in several types of immune cells. (regenerativemedicine.net)
  • The dendritic cells of elite controllers also appear to produce higher levels of a DNA-sensing protein called cGAS that recognizes the presence of HIV and induces rapid expression of type 1 interferons. (regenerativemedicine.net)
  • Plausible physiologic and biologic mechanisms: For example, positing that a major change in organ formation was due to late-trimester pesticide exposure would not be plausible because organogenesis would have been completed before the exposures. (medscape.com)
  • Exposure in this group could occur through exposure to contaminated clothing, through workplace visits with spouses, and through residence proximity to factories, explained the researchers. (sciencedaily.com)
  • The researchers measured myoglobin and creatine kinase levels in subjects who were running the Boston marathon. (enrichgifts.com)
  • BPA, a major molecule used in the plastic industry, has been shown to be an endocrine disruptor that could exert deleterious effects on human health. (clinicalnews.org)
  • In their 2005 review of the literature(2), Drs vom Saall and Claude Hughes wrote that, as of December 2004, there were "115 published in vivo studies concerning low-dose effects of BPA, and 94 of these report significant effects. (archetypeltd.co.nz)
  • Many things, such as smoking, exposure to cigarette smoke, and drinking alcohol can have harmful effects during pregnancy. (littledotapp.com)
  • Exposure to certain everyday substances in our homes, workplaces and outdoor environment can also have harmful effects during pregnancy. (littledotapp.com)
  • Particular emphasis has been given to a discrimination of the effects of external γ-ray exposure and internal α-particle exposure due to incorporated plutonium. (bioone.org)
  • Also, associations between exposure to such substances and endocrine-related health effects in the general population, as well as in wildlife, have been increasingly reported. (5dok.org)
  • Regulatory agencies commonly gave more weight to standard than non-standard studies in risk assessment of BPA, despite the growing amount of research indicating that toxic effects at low doses were being overlooked. (5dok.org)
  • Only after many years, and a plethora of published research showing its toxic effects, did some manufacturers begin to remove BPA from their products. (bitterrootbugle.com)
  • A new class-action lawsuit in the US alleges Coca-Cola and Simply Tropical fruit juice deceived customers with claims of an all-natural, healthy product when the juice has been found to be contaminated with toxic PFAS at levels "hundreds of times" above federal advisory limits for drinking water. (pops.int)
  • In other words, although our study clearly indicates that BPA-induced thyroid disruption is possible, it does not indicate how probable such a disruption is to occur in real conditions," added Viguié. (clinicalnews.org)
  • How does exposure occur? (inalliancepse.org)
  • And damaging exposure can occur as early as in the womb, impacting on the lives and health of our children before they are born. (archetypeltd.co.nz)
  • The first study, published in November 2009 in the Oxford Journals' Human Reproduction, found that exposure to high levels of BPA in the workplace increases the risk of reduced sexual function in men. (sciencedaily.com)
  • DNA methylation changes from primary cultures through senescence-bypassin Syrian hamster fetal cells initially exposed to benzo[a]pyrene. (diagenode.com)
  • This study shows for the first time that exposure to air pollution decreases cord Free T 4 and increases cord Free T 3 level. (thyroid.org)
  • Mercury used in ASGM translates into increases in mercury exposure to women and children. (blogspot.com)
  • To probe if model predictions were in line with this particular premise, we predicted the biomass level as being a function on the WOA uptake charge in treated cultures with and without having gene expression improvements. (pdpksignaling.com)
  • In 2005, a smaller study i n Japan found that 45 women who had three or more first-trimester miscarriages had three times more BPA in their blood than 32 women with no history of pregnancy problems. (lactobacto.com)
  • Fetal exposure t o a commonly used plasticizer found in products such as water bottles, soup can liners and paper receipts, can i ncrease the risk for prostate cancer later in life , according to a study. (lactobacto.com)
  • Exposure to PM2.5 after birth seemed to be the most harmful to testicular function, the study found. (desdaughter.com)
  • It can also slow down a child's growth, both in utero and after birth. (inalliancepse.org)
  • moreover, many risk factors are not conducive to population-level intervention. (biomedcentral.com)
  • Following the results the survey shows a mixed picture: POPs like PCDD and PCFD have fallen steadily from their earlier high level indicating the effectiveness of intervention measures. (blogspot.com)
  • When I first heard of BPA and the dangers it poses, I was about 22 years old and my awareness of the problem and the extent of my concern was my water bottle. (naturalfertilityandwellness.com)
  • Since then, we've learned a lot more about the extent of the damage possible because of BPA exposure and absorption. (naturalfertilityandwellness.com)
  • This half settled my nerves, but I still found myself seeking out items labeled "BPA-free" because it seemed to me that unnecessary exposure to a known toxin didn't seem right. (naturalfertilityandwellness.com)
  • Mercury is also found in compact fluorescent light bulbs and older thermometers, though the largest exposure by far comes from eating mercury-tainted seafood. (inalliancepse.org)
  • We found hope through fetal surgery and today our girls are healthy, active, and bring joy to our lives in ways we could never have imagined. (issuu.com)
  • high exposure route for young children due to playing and crawling on numerous surfaces. (littledotapp.com)
  • Associations between maternal cortisol (continuous and tertiles) and offspring ASD or ADHD traits were examined in regression models adjusted for offspring sex, maternal age, pre-pregnancy BMI, parity, maternal education level, parental psychiatric disorders, and maternal smoking and stratified for offspring sex. (bvsalud.org)
  • [ 2 ] A number of modalities may be required for diagnosis and treatment of exposures in pregnancy. (medscape.com)
  • Exposure to BPA has been reported to reduce birth weight in animal studies at relatively high levels of exposure. (sciencedaily.com)
  • Tuna is famous because it has very low levels of fat and very high levels of protein, minerals, vitamins and PUFAs. (ufaocity.xyz)
  • These are high level, chronic exposures that start before the child is even born, but continue throughout their life. (csn-deutschland.de)
  • It provides the health risk associated with local air pollution levels and advice about when to be active and when to take it easy. (littledotapp.com)
  • This led to the creation of the Fetal Health Foundation. (issuu.com)
  • Connexions is an annual publication of the Fetal Health Foundation, a nationally registered 501(c)(3), non-profit organization located in Colorado. (issuu.com)
  • a glimpse at the fetal health team. (issuu.com)
  • Gamble, Dalia utilizes her expertise in global services, implementing and managing technology, overseeing call centers, and establishing and maintaining strong relationships to help provide strategic direction to the Fetal Health Foundation. (issuu.com)
  • 2010, p. 34) Even when toxic exposures aren't directly involved in creating a particular condition, they can make health problems in general worse by interfering with the functioning of a child's immune response. (keepyourchildsafe.org)