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  • effect
  • Comparison of effect of bcg, glucan and levamisole on b16 melanoma met" by J W. Proctor, B G. Auclair et al. (jax.org)
  • Comparison of effect of bcg, glucan and levamisole on b16 melanoma metastases. (jax.org)
  • and Shibata, H, "Comparison of effect of bcg, glucan and levamisole on b16 melanoma metastases. (jax.org)
  • fluorouracil
  • Levamisole is used with another cancer medicine (fluorouracil) to help make it work better against cancer of the colon. (mayoclinic.org)
  • British researchers reporting in a recent issue of the Journal of the National Cancer Institute offer a study-based explanation of why levamisole and fluorouracil (5-FU), used together, can lengthen survival for certain colon cancer patients, while neither drug alone has consistently been shown to make a difference. (cancernetwork.com)
  • On the basis of laboratory experiments with colon cancer cells, investigators at the University of Leeds (England) propose that levamisole and fluorouracil have complementary effects at the level of RNA activity. (cancernetwork.com)
  • The findings suggest, the investigators say, that levamisole both reduces the toxicity that fluorouracil would otherwise exhibit because of its general suppression of RNA synthesis, and at the same time augments the therapeutic benefit of 5-FU through selective effects on certain messenger RNAs. (cancernetwork.com)
  • A total of 401 eligible patients with resected stages B and C colorectal carcinoma were randomly assigned to no-further therapy or to adjuvant treatment with either levamisole alone, 150 mg/d for 3 days every 2 weeks for 1 years, or levamisole plus fluorouracil (5-FU), 450 mg/m2/d intravenously (IV) for 5 days and beginning at 28 days, 450 mg/m2 weekly for 1 year. (gsajournals.org)
  • cyclosporin
  • In cases of steroid resistant/dependent INS several types of treatment are used, including course of methyloprednisolone "pulses", alkylating agents, cyclosporin A, levamisole and mycophenolate mofetil. (readbyqxmd.com)
  • clinical
  • Michal Šmahel, Ingrid Poláková, Eva Sobotková, and Eva Vajdová, "Systemic Administration of CpG Oligodeoxynucleotide and Levamisole as Adjuvants for Gene-Gun-Delivered Antitumor DNA Vaccines," Clinical and Developmental Immunology , vol. 2011, Article ID 176759, 7 pages, 2011. (hindawi.com)
  • Laboratory values and clinical data were analyzed for three separate periods for each patient: 1 year prior to the initiation of levamisole therapy (Pre-Lev), during 1 year of levamisole therapy (During-Lev), and the year following cessation of levamisole therapy (End-Lev). (biomedsearch.com)
  • receptor
  • Chimeric genes were created to analyse key motifs in gpa unc 38.1 that may affect receptor function and levamisole sensitivity. (bl.uk)
  • Murine and human neutrophils exposed to levamisole demonstrated enhanced NET formation through engagement of muscarinic subtype 3 receptor. (jci.org)
  • biopsy
  • Cutaneous biopsy material obtained from individuals exposed to levamisole suggests that neutrophils produce NETs in areas of vasculitic inflammation and thrombosis. (jci.org)
  • drench
  • The Food and Drug Administration (FDA) is amending the animal drug regulations to reflect approval of a supplemental new animal drug application (NADA) filed by Schering-Plough Animal Health Corp. The supplemental NADA revises the description of various internal parasites in labeling for levamisole powder, used to make a drench solution for oral administration to cattle and sheep. (federalregister.gov)
  • Schering-Plough Animal Health Corp., 1095 Morris Ave., Union, NJ 07083, filed a supplement to NADA 112-051 for LEVASOLE (levamisole) Soluble Drench Powder revising the description of various internal parasites in labeling for levamisole powder, used to make a drench solution for oral administration to cattle and sheep. (federalregister.gov)
  • autoimmune
  • Aberrant NET formation and degradation have been implicated in idiopathic autoimmune diseases that share features with levamisole-induced autoimmunity as well as in drug-induced autoimmunity. (jci.org)
  • Some individuals who consume levamisole-adulterated cocaine can develop a life-threatening autoimmune syndrome. (readbyqxmd.com)
  • agent
  • Levamisole is a known immunomodulating agent frequently used as a cutting agent in cocaine consumed in the United States today. (hindawi.com)
  • CONCLUSION: Thus, our study showed that levamisole is a safe and effective steroid-sparing agent, with long-lasting effect even 12 months after withdrawal. (biomedsearch.com)
  • The use of levamisole, an antihelmithic agent and cancer drug, was discontinued in Canada in August 2005. (biomedcentral.com)
  • Treatment
  • Do not use levamisole without first talking to your doctor if you are pregnant or could become pregnant during treatment. (pharmacy-network.com)
  • Discuss with your doctor the appropriate use of birth control during treatment with levamisole if necessary. (pharmacy-network.com)
  • Your doctor will determine the correct amount and frequency of treatment with levamisole depending upon the type of cancer being treated and other factors. (pharmacy-network.com)
  • Avoid contact with people who have colds, the flu, or other contagious illnesses and do not receive vaccines that contain live strains of a virus (e.g., live oral polio vaccine) during treatment with levamisole. (pharmacy-network.com)